Clinical trials: Insulin Dependent Diabetes
Type 1 Diabetes Mellitus
Beta Cell Imaging During and Shortly After the Honeymoon Phase of T1D
The primary goal is to correlate beta cell mass to beta cell function from measurements during and shortly after the honeymoon phase of type 1 diabetes, to improve understanding of the change in metabolic control after the…
- Trial name
- Honeymoon (NCT03917238)
- Testing
- gallium-68-exendin injection followed by PET/CT scan
- Where
- 2 sites in Netherlands
- Volunteers
- 14 people
- Sponsor
- Radboud University Medical Center
Diabetes, Diabetic Foot
Optimized Care of People With Diabetes and Foot Complication in Primary Care
The goal of this observational study is to create and evaluate and new management, by using eHealth tools, to prevent diabetic foot ulcers. The main questions it aims to answer are: 1. Validation a.
- Conditions
- Diabetes, Diabetic Foot, Diabetes Mellitus, Diabetes Mellitus, Type 2
- Trial name
- NCT05692778
- Testing
- Patients being foot examined by using an eHealth tool, Patients being foot examined in traditional manner
- Where
- Sweden
- Volunteers
- 140 people
- Sponsor
- Sahlgrenska University Hospital
Diabetes Mellitus, Type 1
Sulfonylurea Effects on Glucagon Regulation During Hypoglycemia in Type 1 DM
We aim to demonstrate that oral administration of glibenclamide stimulates pancreatic glucagon secretion during hypoglycemia in insulin-deficient (C-peptide negative) patients with type 1 diabetes when compared to type 1 diabetic…
- Trial name
- NCT00515801
- Testing
- glibenclamide
- Where
- Switzerland
- Volunteers
- 18 people
- Sponsor
- University Hospital, Basel, Switzerland
Diabetes Mellitus, Type 1
Prolonged Remission Induced by Phenofibrate in Children Newly Diagnosed With Type 1 Diabetes.
The goal of this clinical trial is to evaluate of the effect of phenofibrate on the functions of beta cells in children with new diagnosis of type 1 diabetes.
- Trial name
- PRIFEN (NCT05909800)
- Testing
- Phenofibrate
- Where
- 2 sites in Poland
- Volunteers
- 102 people
- Sponsor
- Medical University of Warsaw
Type 1 Diabetes
Impact of Food Carbohydrate and Insulin Dose Computing by on Smart Phone on Glucose Control in Patients With Diabetes
During this study, we will assess a new smart phone application which aims at helping patients with Type 1 diabetes to compute food carbohydrates and meal insulin doses.
- Trial name
- GLUCAL (NCT02676609)
- Testing
- Automated carbohydrate and meal insulin dose computing
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Montpellier
Type 1 Diabetes
Use of Insulin Adjustment Device DreaMed Advisor Pro During Routine Clinical Use for Subjects With Diabetes Type 1
The DreaMed Advisor Pro, is a software which automatically analyses treatment information, learns patient's needs and accordingly suggests adjustments in insulin dosing (FDA approved decision support system).
- Trial name
- NCT04271228
- Testing
- DreaMed Advisor Pro
- Where
- Israel
- Volunteers
- 70 people
- Sponsor
- Rabin Medical Center
Diabetes Mellitus Type 1 Pre-Existing, Pregnancy Related
Closed-Loop Insulin in Mothers With Type 1 Diabetes and Baby Feeding Practices
This study will is a parallel two-group randomized controlled trial that will use the MiniMed 670G hybrid closed-loop system's continuous glucose monitor (GCM) insulin pump and computer algorithm to deliver insulin when in "auto…
- Conditions
- Diabetes Mellitus Type 1 Pre-Existing, Pregnancy Related, Feeding Behavior, Infant Development
- Trial name
- CLIMB (NCT04420728)
- Testing
- Early auto-mode, Delayed auto mode
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Diabetes Mellitus, Type 1
Imaging Inflammation in Autoimmune Diabetes
The purpose of this study is to determine whether magnetic resonance imaging (MRI) with ferumoxtran-10 can be used to detect changes in the pancreas associated with autoimmune diabetes.
- Trial name
- NCT00585936
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Joslin Diabetes Center
Type 1 Diabetes
Islet Allotransplantation in Type 1 Diabetes
Islet transplantation can provide physiologic insulin replacement to patients with type 1 diabetes without the complications associated with whole pancreas transplantation.
- Trial name
- NCT01705899
- Testing
- Human Pancreatic Islets
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Ohio State University
Type 1 Diabetes Mellitus
Structured Carbohydrate-Counting Education in Adults With Type 1 Diabetes
This study evaluated changes in glycemic outcomes following a structured carbohydrate-counting education program in adults with type 1 diabetes using continuous glucose monitoring (CGM).
- Trial name
- NCT07834801
- Testing
- Carbohydrate counting education
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Acibadem University
Type 1 Diabetes
Short Term Closed-loop Glucose Control in Adults With Type 1 Diabetes
The main objective of this study is to determine the feasibility, efficacy and safety of automated closed-loop glucose control in the home setting over a short term period.
- Trial name
- AP@home02 (NCT01666028)
- Testing
- FlorenceD or similar closed loop glucose control system, CSII with real-time CGM
- Where
- 3 sites in Austria, Germany and 1 more
- Volunteers
- 18 people
- Sponsor
- University of Cambridge
Diabetes Mellitus, Type 1
Pilot Study of Brief Intervention to Support Diabetes Health-Related Quality of Life
The aims of this pilot study are to evaluate the feasibility, acceptability, preliminary impact, and costs of a brief, behavioral intervention delivered remotely by diabetes educators to people with type 1 diabetes and their…
- Trial name
- T1DALPilot (NCT05234944)
- Testing
- Type 1 Diabetes and Life
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- Baylor College of Medicine
Diabetes, Diabetes Mellitus, Type 1
Safety and Efficacy of NovoLog vs. Humalog in Insulin Pumps in Children and Adolescents
This trial is conducted in the United States of America (USA). It is demonstrated that intensive insulin therapy resulting in good glycaemic control can reduce or delay the incidence of complications secondary to Type 1 Diabetes.
- Trial name
- NCT00097071
- Testing
- insulin lispro, insulin aspart
- Where
- 52 sites in United States
- Volunteers
- 299 people
- Sponsor
- Novo Nordisk A/S
Type 1 Diabetes Mellitus
Pilot Study 1 of Outpatient Control-to-Range - System and Monitoring Testing
A single arm, single treatment study is proposed to assess the feasibility of a portable artificial pancreas system outside of a hospital based clinical research center.
- Trial name
- NCT01470807
- Testing
- portable artificial pancreas system with CTR algorithms
- Where
- Italy
- Volunteers
- 5 people
- Sponsor
- University of Virginia
Diabetes, Diabetes Mellitus, Type 1
Surveillance Study of NovoRapid® for New Drug Re-examination
This study is conducted in Asia. The aim of this study is to observe the safety and efficacy of insulin aspart (NovoRapid®) administered via vial and three different devices.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- NCT01490112
- Testing
- insulin aspart
- Where
- South Korea
- Volunteers
- 1,239 people
- Sponsor
- Novo Nordisk A/S
Type 1 Diabetes
Study of A Cell-Phone System to Improve Health of Youth With Diabetes
FL3X is an integrated diabetes self-management system that incorporates modern cell phone technology with behavioral modification approaches to improve diabetes self-management in high-risk youth.
- Trial name
- FL3X (NCT02280564)
- Testing
- health coaching with technology support
- Where
- 3 sites in United States
- Volunteers
- 74 people
- Sponsor
- University of North Carolina, Chapel Hill
Diabetes Mellitus - Type 1, Diabetes Mellitus - Type 2
The BRIGHT Study (Device Name: HALO System)
The purpose of the BRIGHT study is to evaluate safety and performance of the HALO SYSTEM in subjects with diabetes mellitus. The primary objectives of this clinical investigation are 1) the evaluation of sensor's performance by…
- Conditions
- Diabetes Mellitus - Type 1, Diabetes Mellitus - Type 2, Diabetes Mellitus, Ketoacidosis, Diabetic
- Trial name
- NCT07745998
- Testing
- The HALO System
- Volunteers
- 12 people
- Sponsor
- Indigo Diabetes NV
Type 1 Diabetes, Diabetes Mellitus, Type 1
Glycemic Effects of the COVID-19 Booster Vaccine in Type 1 Diabetes
Vaccines for COVID-19 are an essential part of combating the coronavirus pandemic. Vaccines "prime" the immune system against an invader (in this case the SARS-CoV-2 virus) by causing a temporary increased immune or inflammatory…
- Trial name
- NCT05233592
- Testing
- CGM
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Johns Hopkins University
Diabetes Mellitus, Type 1
Different Dietary Interventions and Glycemia in T1DM
The aim of the present study was to compare the effects of three different dietary patterns on glycemia in individuals with type 1 diabetes (T1D).
- Trial name
- NCT04343131
- Testing
- Dietary intervention
- Volunteers
- 15 people
- Sponsor
- National and Kapodistrian University of Athens
Type 1 Diabetes
EFFECT OF HYBRID CLOSED-LOOP SYSTEMS ON CARDIOVASCULAR MARKERS IN TYPE 1 DIABETES.
This is a prospective, non-randomized, observational cohort study conducted in adult patients with type 1 diabetes.Participants with poorly controlled T1D under multiple daily injection (MDI) treatment will be assigned to one of…
- Trial name
- NCT07241702
- Testing
- HCLS, SGLT2 inhibitor, MDI
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Attikon Hospital
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