Clinical trials: Insulin Dependent Diabetes
Type 1 Diabetes
Fear of Hypoglycemia and Glycemic Variability
Subjects with type 1 diabetes are invited to provide usual blood glucose monitoring and a blood glucose profile (Pre/ post prandial Blood Glucose + Night Blood Glucose) on 3 occasions in a 2 week time period, in addition to the…
- Trial name
- VARDIA (NCT02790060)
- Where
- 9 sites in France
- Volunteers
- 600 people
- Sponsor
- Poitiers University Hospital
Type 1 Diabetes Mellitus
Optimizing Adherence and Glycemia in Youth With New Insulin-dependent Diabetes Mellitus (IDDM)
This 2-year randomized, controlled trial examined the impact of a clinic-based, family teamwork intervention on glycemic control in youth with recently diagnosed type 1 diabetes.
- Trial name
- NCT00745342
- Testing
- Family Teamwork Intervention
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Joslin Diabetes Center
Type 1 Diabetes
The Effect of Sea Buckthorn Extract in Patients With Type 1 Diabetes
Type 1 diabetes (T1D) is an autoimmune disease characterized by the destruction of insulin-producing β-cells by autoreactive T cells.
- Trial name
- SBTT1D (NCT07787754)
- Testing
- Sea buckthorn
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Type 1 Diabetes Mellitus
Endothelial Dysfunction and Diabetes
The aim of the study is to progress in the understanding of the early retinal vascular and neural abnormalities in patients with diabetes, using a new device, the Dynamic Vessel Analyzer.
- Trial name
- DENDI (NCT01097551)
- Testing
- Trinitrin, Neosynephrine 10% collyrium, Iontophoresis with acetylcholine delivery
- Where
- France
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetes Mellitus, Type 1, Adolescent Behavior
Pet Ownership and Glucose Control in Early Adolescents With Type 1 Diabetes
This study evaluates the short-term effects of incorporating the structured care of a pet fish into a diabetes self-care routine on glucose control in early adolescents with type 1 diabetes.
- Trial name
- NCT03761251
- Testing
- Pet Fish
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Texas Southwestern Medical Center
Type 1 Diabetes Mellitus, Covid19
Evaluation of Quality of Life in Patients With Type 1 Diabetes Mellitus During the Covid-19 Pandemic
During the COVID-19 pandemic, the time spent at the home of patients has increased because of national quarantine policies and patients' fear of getting sick.
- Trial name
- NCT04558645
- Testing
- Online Survey
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Gazi University
Diabetes Type 1
A Study of LY900014 and Insulin Lispro With an External Continuous Subcutaneous Insulin Infusion System in Adult Participants With Type 1 Diabetes
The purpose of this study is to evaluate the compatibility and safety of LY900014 and insulin lispro with an external continuous subcutaneous insulin infusion system in adult participants with type 1 diabetes.
- Trial name
- PRONTO-Pump (NCT03433677)
- Testing
- LY900014, Insulin lispro
- Where
- 5 sites in United States, Spain
- Volunteers
- 49 people
- Sponsor
- Eli Lilly and Company
Educational Activities
The SUPPORT-Pro Online Platform for Healthcare Professionals Treating Individuals Living With T1D
Health care professionals (HCPs) help an support patients living with type 1 diabetes (PWT1D) who need to achieve optimal blood glucose control in order to prevent short and long term complications of T1D.
- Trial name
- SUPPORT-Pro (NCT04859205)
- Testing
- Intervention
- Where
- Canada
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- McGill University
Type1diabetes
Self Efficacy Levels, Attachment Style and Resiliency of Youth With Type 1 Diabetes
This project will assess self-efficacy levels(SE) ,resiliency and attachment style of adolescent with type 1 diabetes and their caregivers.SE and attachment style of patients and parents will be compared with each other as well…
- Trial name
- NCT04172077
- Where
- Canada
- Volunteers
- 170 people
- Sponsor
- The Hospital for Sick Children
Type 1 Diabetes Mellitus
Check It! Positive Psychology Intervention to Improve Adherence in Adolescents With T1D
Problems with diabetes management in adolescents with type 1 diabetes are common - occurring at rates as high as 93% - and have serious health consequences, including poor blood sugar control and risk for later complications.
- Trial name
- NCT02746627
- Testing
- Positive Affect, Education
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Vanderbilt University Medical Center
Type 1 Diabetes
Sweetgoals for Type 1 Diabetes
The study will test an app and web-delivered intervention designed to improve glycemic control (HbA1c) among young adults with Type 1 diabetes.
- Trial name
- NCT04646473
- Testing
- Coaching, Incentives, Sweetgoals app
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Trustees of Dartmouth College
Type 1 Diabetes, Diabetes Mellitus
Community Health Workers in Pediatric Patients With Newly Diagnosed Type 1 Diabetes
The primary aim of this pilot randomized controlled trial is to determine if the integration of a Community Health Worker (CHW) into the healthcare team of children with newly diagnosed type 1 diabetes is associated with an…
- Conditions
- Type 1 Diabetes, Diabetes Mellitus, Psychosocial Problem, Compliance, Patient
- Trial name
- NCT04238949
- Testing
- Community Health Worker added to diabetes team
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Children's Hospital of Philadelphia
T1DM - Type 1 Diabetes Mellitus
JAK1 Inhibitor Ivarmacitinib for Improving Pancreatic Islet Function in T1D
This is a double-blind, randomized, placebo-parallel-controlled, multicenter study. The objective is to evaluate the efficacy and safety of Ivarmacitinib 8 mg administered for 52 weeks in preserving pancreatic β cell function in…
- Trial name
- INSPIRE-T1D (NCT07845955)
- Testing
- Ivarmacitinib
- Where
- China
- Volunteers
- 132 people
- Sponsor
- Huijie Zhang
Type1 Diabetes Mellitus
The Survey of Treatment and Metabolic Status of Type 1 Diabetes Mellitus (T1DM).
This study is a multicenter cross-sectional research project, planning to enroll 1000 patients with Type 1 Diabetes Mellitus (T1DM).
- Trial name
- NCT06606509
- Testing
- Continuous Glucose Monitoring System (GX-01S)
- Where
- 101 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Type 1 Diabetes Mellitus
IMCY-T1D-002: Long-term Follow-up Study of T1D Patients Previously Treated With IMCY-0098 or Placebo
This study is the follow-up of study IMCY-T1D 001 (EudraCT: 2016-003514-27, NCT03272269) in which patients with recent onset T1D have been treated with IMCY-0098 or placebo.
- Trial name
- IMCY-T1D-002 (NCT04190693)
- Where
- 19 sites in Belgium, Denmark and 5 more
- Volunteers
- 30 people
- Sponsor
- Imcyse SA
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
GLUCOME USABILITY STUDY
The GlucoMe device, in its original packaging, along with the user manual and QuickStart guide will be provided to the patient in a simulated home use environment.
- Trial name
- NCT02488278
- Testing
- GlucoMe Glucose Monitoring Device
- Sponsor
- GlucoMe
Type 1 Diabetes Mellitus
Repeated Dosing Study With a New Insulin Glargine Formulation and Lantus® in Patients With Type 1 Diabetes Mellitus
Primary Objective: To assess the safety and tolerability of two dose levels of a new insulin glargine formulation in a once-daily multiple dosing regimen Secondary Objective: To compare the pharmacokinetic and pharmacodynamic…
- Trial name
- NCT01349855
- Testing
- Insulin glargine HOE901
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Sanofi
Diabetes Mellitus, Type I, IDDM
SteadiSet™ Pilot Study (SteP Study)
This study will evaluate the safety and effectiveness of how well blood glucose is managed when a participate wears the investigational SteadiSet™ Infusion Set (SteadiSet device) for up to 14 days post-insertion when compared to…
- Conditions
- Diabetes Mellitus, Type I, IDDM, Diabetes Mellitus, Insulin-Dependent, 1, Type 1 Diabetes
- Trial name
- NCT04591925
- Testing
- Control Device insulin infusion devcie, Investigative insulin infusion devcie
- Where
- Austria
- Volunteers
- 13 people
- Sponsor
- Capillary Biomedical, Inc.
Type 1 Diabetes (T1D)
Feasibility Study of a Continuous Glucose-Ketone Monitoring Device in People With Type 1 Diabetes
The goal of this study is to evaluate a CGM-CKM device during insulin suspension in patients with type 1 diabetes. 10 patients with T1D will be recruited for a pilot study. The patients will visit CTRU at Stanford Medical School.
- Trial name
- NCT06977633
- Testing
- Temporary Insulin Suspension, Glucose and ketone sensor
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mahla Poudineh
Type1diabetes
Personalized Automated Determination of Insulin Pump Setting for Subjects With Type 1 Diabetes Switching From MDI to Pump Therapy and Vice Versa- Safety and Efficacy Feasibility Study
The "MD-Logic Switch Advisor" is a software product that is designed to assist in insulin dosage decision making and has two components: A.
- Trial name
- NCT03574558
- Testing
- MD-Logic Switch Advisor
- Where
- Israel
- Volunteers
- 28 people
- Sponsor
- Rabin Medical Center
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