Clinical trials: Insulin Dependent Diabetes
Type 1 Diabetes
Pilot Study 3 of Outpatient Control-to-Range: Safety and Efficacy With Day-and-Night In-Home Use
The purpose of this study is to see if an automated insulin management system ("study system") can safely be used at home to manage blood sugar.
- Trial name
- CTR3 (NCT02137512)
- Testing
- Closed-Loop Control System, Sensor-Augmented Pump (SAP)
- Where
- 6 sites in United States, France and 2 more
- Volunteers
- 30 people
- Sponsor
- Jaeb Center for Health Research
Type 1 Diabetes Mellitus
A Study Comparing LY900014 to Insulin Lispro (Humalog) in Children and Adolescents With Type 1 Diabetes
The reason for this study is to compare the study drug LY900014 to insulin lispro (Humalog) in children and adolescents with type 1 diabetes (T1D).
- Trial name
- PRONTO-Peds (NCT03740919)
- Testing
- LY900014, Insulin Lispro, Insulin Glargine
- Where
- 111 sites in United States, Austria and 16 more
- Volunteers
- 751 people
- Sponsor
- Eli Lilly and Company
Diabete Type 1, Educational Videos
Interactive Educational Video for Paediatric Type 1 Diabetes
The primary aim of this study is to evaluate the effectiveness of an interactive educational video (Luca's Journey: Managing Type 1 Diabetes) delivered in addition to the standard educational programme, in improving metabolic…
- Trial name
- Intedu (NCT07639307)
- Testing
- Interactive Educational Video (Luca's Journey: Managing Type 1 Diabetes), Traditional Face-to-Face Education
- Volunteers
- 110 people
- Sponsor
- G. d'Annunzio University
Diabetes Mellitus, Type 1
UVA Islet Cell Transplantation in Patients With Type I Diabetes
This protocol will provide islet cell transplantation to two separate populations in need of a pancreas transplant: Group I: Islet Cell Transplantation in Type I Diabetics without Kidney Problems Group II: Islet Cell…
- Trial name
- NCT00605592
- Testing
- Pancreatic Islets of Langerhans Cell Transplant
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Virginia
Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus
CGM Utilization With IV Insulin EndoTool and Subcutaneous Insulin in the Neuro ICU
The goal of this study (CGM utilization with IV Insulin EndoTool and Subcutaneous Insulin in the Neuro ICU) is to understand how CGM technology utilized in conjunction with EndoTool IV insulin could improve glycemic management in…
- Conditions
- Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus, Hyperglycemia
- Trial name
- NCT05857007
- Testing
- Libre 2.0 CGM in patients taking subcutaneous insulin with concomitant high dose glucocorticoids
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Wake Forest University Health Sciences
Diabetes Mellitus, Type 1 Diabetes
Tandem Predictive Low Glucose Suspend Inpatient Feasibility Study
The goal of this study is to assess the functionality of an integrated predictive low glucose suspend system designed to minimize the incidence and duration of hypoglycemia by suspending insulin delivery if hypoglycemia is…
- Conditions
- Diabetes Mellitus, Type 1 Diabetes, Insulin Pump
- Trial name
- NCT02877771
- Testing
- t:slim insulin pump with predictive low glucose suspend
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Tandem Diabetes Care, Inc.
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Application of UCPCR as a Testing Tool for Identification of MODY Patients in the UAE
The study aims to investigate the validity of 2 hour post-prandial UCPCR test in paediatric and adult patients with diabetes duration greater than 2 and 5 years, respectively, for the purposes of distinguishing between patients…
- Conditions
- Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Maturity-onset Diabetes of the Young
- Trial name
- NCT03607604
- Testing
- Next generation sequencing (NGS)
- Where
- United Arab Emirates
- Volunteers
- 778 people, healthy volunteers welcome
- Sponsor
- Imperial College London Diabetes Centre
Type 2 Diabetes
Insulinotropic Effect of GLP-1 and GIP After Dexamethasone
In this study we examine whether inducing insulin resistance by dexamethasone in healthy volunteers will lead to a decreased insulinotropic effect of the hormones GLP-1 and GIP.
- Trial name
- NCT02235584
- Testing
- Dexamethasone
- Where
- Denmark
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Type I Diabetes
Measurement of Total Retinal Blood Flow in Patients With Diabetes and Healthy Subjects
The prevalence of diabetes and diabetes-associated complications is still increasing. Several major long-term complications of diabetes such as cardiovascular disease, chronic renal failure, diabetic retinopathy and others relate…
- Trial name
- NCT01843114
- Testing
- FDOCT, Dynamic Vessel Analyzer
- Where
- Austria
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Alopecia Areata, Depressive Episode
The Epidemiology, Management, and the Associated Burden of Related Conditions in Alopecia Areata
This study series consists of four related studies and aims to explore and describe many important elements of alopecia areata over three key areas: (1) the current epidemiology of alopecia areata, (2) the prevalence and…
- Conditions
- Alopecia Areata, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorders
- Trial name
- NCT04239521
- Testing
- Exposure of interest (studies 2 & 3).
- Where
- United Kingdom
- Volunteers
- 51,955 people
- Sponsor
- Momentum Data
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Implementing Continuous Glucose Monitoring in Primary Care for Patients With Diabetes
The overarching goal of this study is to decrease disparities and increase access to continuous glucose monitoring (CGM) for patients with diabetes, regardless of where people receive their diabetes care.
- Conditions
- Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Continuous Glucose Monitoring
- Trial name
- PREPARE4CGM (NCT05336214)
- Testing
- Virtual CGM initiation service, Online educational module on CGM, Practice facilitation
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- University of Colorado, Denver
Diabetes Mellitus, Type 1
The Diabetes Patient-Reported Outcome Measures Trial
The study aim to evaluate the use of Patient-Reported Outcome Measures in clinical diabetes consultations.
- Trial name
- DiaPROM (NCT03471104)
- Testing
- PAID in clinical diabetes consultations
- Where
- Norway
- Sponsor
- Haukeland University Hospital
Diabetes Mellitus, Type 1
The Effects of a Low Carbohydrate, Non-Ketogenic Diet Versus Standard Diabetes Diet on Glycemic Control in Type 1 Diabetes
This randomized, crossover nutrition intervention seeks to examine the effects of a non-ketogenic low carbohydrate (CHO) diet (60-80g per day) on glycemic control, lipids, and markers on inflammation in individuals with Type 1…
- Trial name
- T1DLoCHO (NCT03544892)
- Testing
- Low carbohydrate diet, Standard of care diet
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Oklahoma
Diabetes Mellitus, Type 1
Insulin-plus-pramlintide Closed-loop Strategy to Regulate Glucose Levels Without Carbohydrate Counting
Closed-loop system systems that are shown to alleviate the burden of carbohydrate counting without degrading glucose control are still lacking.
- Trial name
- Dual (NCT03800875)
- Testing
- 27-hour inpatient intervention
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- McGill University
Diabetes, Diabetes Mellitus, Type 1
A Survey on Low Blod Sugar Among Insulin-treated Patients With Diabetes
This study is conducted globally. The aim of this study is to describe the proportion of patients with hypoglycaemic episodes and estimate the incidence of various types of hypoglycaemia in the retrospective and prospective…
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- NCT02306681
- Testing
- No treatment given
- Where
- 8 sites in Bangladesh, Colombia and 6 more
- Volunteers
- 7,315 people
- Sponsor
- Novo Nordisk A/S
Type 1 Diabetes,, Bone
Skin Blood Flow in Patients With Type 1 Diabetes Mellitus Compared to Normal Controls
The effects of high serum glucose on bone could be direct or could be indirect through its effects on the microvasculature. Previous studies by Rendell et al and Brugler et al have found significant differences in skin blood flow…
- Trial name
- NCT01592539
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Creighton University
Type 1 Diabetes, Type 2 Diabetes
The Genetics of Diabetes in Southern California Chinese Americans
The purpose of this research study is to investigate the genetic causes of diabetes. Specifically, we are interested in the mitochondrial genome and how variants in the mitochondrial genome influence a person's risk to develop…
- Conditions
- Type 1 Diabetes, Type 2 Diabetes, Metabolic Syndrome
- Trial name
- NCT00824395
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine
Diabetes Mellitus
Diabetes Type 1 and Fitness.
The Diab1Fit Study project aims to a multidirectional assessment of physical activity and its impact in people with type 1 diabetes (DM1).
- Trial name
- Diab1Fit (NCT04968171)
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Poznan University of Medical Sciences
Type 1 Diabetes
Use of an Automated Insulin Delivery System Compared to Sensor Augmented Pump at Patients With Type 1 Diabetes (T1D)
Title: An open-label, three-center, randomized, cross-over study to evaluate the safety and efficacy of day and night closed-loop control using the MD-Logic automated insulin delivery system compared to sensor augmented pump…
- Trial name
- DREAM5 (NCT02636491)
- Testing
- MD-Logic-Automated Insulin Delivery System, MiniMed Paradigm® Veo™ System
- Where
- Germany
- Volunteers
- 45 people
- Sponsor
- Kinderkrankenhaus auf der Bult
Diabetes Mellitus
Evaluation of an Ascensia Blood Glucose Meter and App System
The purpose of this study is to assess the usability of the Onyx system in the hands of subjects with Insulin Dependent Diabetes Mellitus (IDDM) or insulin-using subjects with Non-IDDM.
- Trial name
- NCT02568384
- Testing
- Onyx BG Meter / App System
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Ascensia Diabetes Care
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