Clinical trials: Insulin Pump Therapy
Type 1 Diabetes, Insulin Pump Therapy
MD Logic Pump Advisor- Adults Study
Prospective, randomized, controlled, 30-78 days trial comparing MD-Logic pump algorithm to the standard of care of patients with type 1 diabetes.
- Trial name
- NCT01157923
- Testing
- MD Logic Pump Advisor
- Where
- 2 sites in Israel, Slovenia
- Volunteers
- 18 people
- Sponsor
- Rabin Medical Center
Diabetes Mellitus, Type 1
A Study of LY900014 Formulation in Participants With Type 1 Diabetes Mellitus Using Insulin Pumps
This study evaluated a blood sugar lowering insulin, LY900014, delivered by an insulin pump continuously under the skin. The study was conducted in participants with type 1 diabetes mellitus to investigate how the human body…
- Trial name
- NCT02703324
- Testing
- LY900014, Insulin Lispro
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Eli Lilly and Company
Type 1 Diabetes
Cross-over Study to Evaluate the Safety and Efficacy of Night Closed-loop Control Using the MD-Logic Automated Insulin Delivery System Compared to Sensor Augmented Pump Therapy in Poorly Controlled Patients With Type 1 Diabetes
The MD-Logic Automated Insulin Delivery System is intended for patients with type 1 diabetes mellitus for subcutaneous infusion of insulin and the continuous measurement of interstitial glucose to aid in the management of their…
- Trial name
- NCT02733211
- Testing
- MD- Logic Closed Loop System, sensor augmented pump therapy
- Where
- 2 sites in Germany, Israel
- Sponsor
- Rabin Medical Center
Closed Loop, Diabetes Mellitus, Type 1
Diabeloop WP6.2 : Crossover Evaluation of Glycemic Control
The study will be conducted in crossover trial, with two 72-hour hospitalization separated by a period Wash-out of at least one week. Each hospitalization is a period of treatment.
- Trial name
- WP6-2 (NCT02627911)
- Testing
- Diabeloop System, Continuous Glucose Monitoring, Accelerometer and heart rate monitor
- Where
- 9 sites in France
- Volunteers
- 36 people
- Sponsor
- Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète
Diabetes Insulin Dependent
Evaluation of Interests of FIT Therapy on Diabetics Children Insulin-dependent
Evaluation of interests of the functional insulin therapy (FIT Therapy) on metabolic control, hypoglycemia prevention and life quality of diabetics children insulin-dependent treated with insulin pump.
- Trial name
- DIABFIT (NCT01443741)
- Testing
- Therapeutic education
- Where
- 6 sites in France
- Volunteers
- 88 people
- Sponsor
- University Hospital, Angers
Type 1 Diabetes
Accu-Chek Combo in Young Patients
This is an open, prospective, descriptive study aiming to evaluate the change in treatment satisfaction of primary care givers of young children who use the Accu-Chek Combo System.
- Trial name
- NCT01657630
- Testing
- Accu-Chek Combo System
- Where
- Israel
- Volunteers
- 13 people
- Sponsor
- Rabin Medical Center
Type 1 Diabetes Mellitus, Cognitive Change
The VRIF Trial: Hypoglycemia Reduction With Automated-Insulin Delivery System
The objective of this pilot study is (i) to test the use of an Artificial Pancreas (AP) System as a viable therapy treatment for two vulnerable populations: 6 to 10 year-old and adults older ≥65 years old with T1D; (ii) to assess…
- Trial name
- NCT03674281
- Testing
- SAP, CLC
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Virginia
Type 1 Diabetes
Energy Balance Following Islet Transplantation
Islet transplantation may be appropriate in up to 10% of adults with Type 1 diabetes who suffer repeated episodes of hypoglycaemia with severely impaired awareness of hypoglycaemia (IAH) (1).
- Trial name
- EBFIT (NCT03063229)
- Testing
- Accelerometer, Anthropomentry, Blood tests
- Where
- United Kingdom
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Insulin Pump Therapy
Closed Loop Pumps vs. Traditional Open Loop Pumps in Managing Blood Glucose Levels in T1DM Patients Fasting in Ramadan.
Our proposed study aims to build upon the existing findings by conducting a first-of-its-kind randomized controlled trial (RCT) that directly compares Advanced Hybrid Closed Loop (AHCL) and open-loop insulin delivery (OLID)…
- Trial name
- HybridRam (NCT06416202)
- Testing
- Advanced hybrid closed loop insulin pump, Open Loop Insulin Delivery system
- Where
- Saudi Arabia
- Volunteers
- 75 people
- Sponsor
- King Fahad Medical City
Diabetes Type 1
Transition of T1DM Patients Aged Over 65 Years Into AHCL (780G) Insulin Pump
Older people with diabetes have a higher risk for cognitive impairment and for physical disability whether this may be effected by an improvement in glucose indices is unknown.
- Trial name
- 780G65+ (NCT06207838)
- Testing
- MiniMed 780G system
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Jagiellonian University
Type 1 Diabetes
Closing the Loop in Adults With Type 1 Diabetes (CLEAR)
The main objective of this study is to determine whether home use of fully closed-loop glucose control applying ultra-rapid Lispro insulin is superior to standard insulin pump therapy with continuous glucose monitoring (CGM) in…
- Trial name
- NCT04977908
- Testing
- CamAPS HX, Standard insulin pump therapy with CGM
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- University of Cambridge
Diabetes Mellitus, Type 2
A Study to Evaluate Eli Lilly's Insulin Dosing Algorithm to Control Glycemia in Insulin-treated Adults With Type 2 Diabetes
The objective of this study is to generate preliminary data in an inpatient setting to help optimize an insulin dosing logic (that decides how much to deliver insulin) for Eli Lilly's system.
- Trial name
- NCT05514080
- Testing
- Insulin closed-loop
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- McGill University
Type 1 Diabetes
Use of an Automated Insulin Delivery System Compared to Sensor Augmented Pump at Patients With Type 1 Diabetes (T1D)
Title: An open-label, three-center, randomized, cross-over study to evaluate the safety and efficacy of day and night closed-loop control using the MD-Logic automated insulin delivery system compared to sensor augmented pump…
- Trial name
- DREAM5 (NCT02636491)
- Testing
- MD-Logic-Automated Insulin Delivery System, MiniMed Paradigm® Veo™ System
- Where
- Germany
- Volunteers
- 45 people
- Sponsor
- Kinderkrankenhaus auf der Bult
Diabetes Mellitus, Insulin-Dependent
Insulin Pump Therapy in Adolescents With Newly Diagnosed Type 1 Diabetes (T1D)
Within 4 weeks after diagnosis of type 1 diabetes, 10 subjects (pubertal males, 12-17 years old) will be randomized to either receive multiple daily injection (MDI) using Lantus insulin, or continuous subcutaneous insulin…
- Trial name
- NCT00357890
- Testing
- Insulin pump therapy, Multiple daily injections using insulin glargine + rapid acting analog
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Nemours Children's Clinic
Type 1 Diabetes Mellitus
Web-Based Follow-Up Using Cellular Phone in Type 1 Diabetic Patients Under Insulin Pump Therapy : The PumpNet Study
The purpose of this study is to determine if telecare using modern telecommunication devices can improve the metabolic control and the quality of life of type 1 diabetic patients.
- Trial name
- NCT00324584
- Testing
- Telemonitoring of glucose values using GlucoNet device
- Where
- 2 sites in France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Grenoble
Hyperglycemia
Sensor-Augmented Insulin-Pump Therapy in New-onset Diabetes After Transplantation
The SAPT-NODAT study will test the hypotheses that intensive subcutaneous insulin treatment with short acting insulin, applied continuously through an insulin pump, (i) improves glycemic control, (ii) reduces the prevalence of…
- Trial name
- SAPT-NODAT (NCT01680185)
- Testing
- Insulin lispro, Humalog (Eli Lilly) in insulin pump, Human insulin isophane, Humulin N (Eli Lilly), Standard of care
- Where
- Austria
- Volunteers
- 85 people
- Sponsor
- Medical University of Vienna
Diabetes Mellitus, Type 1
Treatment of Low Blood Sugar With Glucagon Among Patients With Type 1 Diabetes
Background: Patients with type 1 diabetes (T1D) need a lifelong supply of external insulin and are advised to aim for near-normalization of blood glucose levels through intensive insulin therapy.
- Trial name
- GluST1 (NCT02232971)
- Testing
- Glucagon, Isotonic saline solution
- Where
- Denmark
- Volunteers
- 8 people
- Sponsor
- Hvidovre University Hospital
Diabetes Mellitus
Closed-loop Insulin Delivery in the General Ward
The study assesses the efficacy and safety of closed-loop glucose control in patients with insulin-treated type 2 diabetes. Phase 1 The study objective is to compare conventional insulin therapy with closed-loop glucose control…
- Trial name
- ANGIE02 (NCT01774565)
- Testing
- Fully Automated Closed-Loop Insulin Delivery, Conventional insulin therapy
- Where
- 2 sites in Switzerland, United Kingdom
- Volunteers
- 43 people
- Sponsor
- University of Cambridge
Type 1 Diabetes
Absorption of Insulin Following Subcutaneous Bolus Administration With Different Bolus Durations
To cover meal-related insulin requirements, insulin pumps allow insulin to be delivered at high rates over a short period of time (bolus delivery).
- Trial name
- NCT01792323
- Testing
- Insulin LISPRO
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- Medical University of Graz
Type 1 Diabetes
The Performance of an Artificial Pancreas at Home in People With Type 1 Diabetes
The overall aim of the study is to evaluate the performance of Artificial Pancreas or Closed Loop Glucose-Sensing Insulin-Delivery system in comparison to current best available technology represented by Sensor Augmented Pump…
- Trial name
- NCT02040571
- Testing
- Closed Loop, Open Loop
- Where
- Australia
- Volunteers
- 28 people
- Sponsor
- St Vincent's Hospital Melbourne