Clinical trials: Insulin Resistance
Insulin Resistance
The Effects of L-Arabinose and D-xylose on Intestinal Sucrase Activity in Man
The purpose of this study is to investigate the effect of L-arabinose and D-xylose in a sugar-rich drink on intestinal sucrase activity in healthy volunteers by measuring postprandial blood glucose and insulin, and selected…
- Trial name
- M192 (NCT01957098)
- Testing
- Active comparator: 4% D-xylose, Active comparator: 8% D-xylose, Active comparator: 8% L-arabinose
- Where
- Denmark
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Metabolic Syndrome
Metformin and Dietary Restriction to Prevent Age-related Morbid Events in People With Metabolic Syndrome
Phase III randomized controlled trial on men and women with Metabolic syndrome (MetS) to test the hypothesis that comprehensive life-style changes and/or metformin treatment prevent age-related chronic non-communicable diseases…
- Trial name
- MeMeMe (NCT02960711)
- Testing
- Metformin Hydrochloride 850 MG Oral Tablet [Glucophage], Ludipress, mg stereate, micronized hydrated silica, talcum
- Where
- Italy
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Prediabetes
Effect of a Nutritional Product Containing Carob Extract on Carbohydrate Metabolism in Glucose-intolerant Subjects
Randomized, controlled, double-blind clinical trial with two parallel arms based on the product consumed (experimental product and placebo product) and conducted at a single center, to measure the efficacy of the liquid NUTIFOOD…
- Trial name
- NUTIFOOD (NCT07420998)
- Testing
- Experimental Product, Control product
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Insulin Resistance
The Effect of 12-week Circuit Training on Insulin Sensitivity and Endothelial Function in Women With Insulin Resistance
During the last 10 years many studies concerning the impact of physical training on whole-body insulin sensitivity have been published, but there is a lack of an extended investigation on the potential clinical benefits of novel…
- Trial name
- NCT04528693
- Testing
- Circuit training (combination of strength and endurance exercises)
- Where
- Poland
- Volunteers
- 49 people
- Sponsor
- Poznan University of Physical Education
Metabolic Syndrome
Pilot Study to Evaluate the Effect of Two Microalgae Consumption on Metabolic Syndrome
The purpose of this study is to evaluate the effect of the consumption of two microalgae Chlorella vulgaris and Arthrospira platensis (Spirulina) on some biomarkers of metabolic syndrome: Total cholesterol, HDL cholesterol, LDL…
- Trial name
- ALGAENERGY (NCT05343858)
- Testing
- Experimental: Group 1: Spirulina platensis, Experimental: Group 2: Chlorella vulgaris
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Shift-Work Related Sleep Disturbance, Metabolic Syndrome
Health Effect of Canola Oil Consumption in Shift Workers
Shift work is associated with a higher risk of the development of cardiometabolic syndrome (CMtS) than in people working only during the day.
- Conditions
- Shift-Work Related Sleep Disturbance, Metabolic Syndrome, Diet Modification, Work-Related Condition
- Trial name
- NCT03977558
- Testing
- Intervention group, Control group
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Poznan University of Life Sciences
Metabolic Syndrome
Exercise Training on Metabolic Syndrome Severity in Employees
Hypothesis: An occupational 6 months physical exercise training will lead to better health behaviour and improve the severity of the metabolic syndrome.
- Trial name
- NCT03293264
- Testing
- Exercise training group
- Where
- Germany
- Volunteers
- 314 people
- Sponsor
- Hannover Medical School
Aging, Menopause
Gonadal Hormone, Gonadotropin and Cardiovascular Events
Deficiency in gonadal hormone has been considered to play a role in ageing related increased incidence of cardiovascular events. But the mechanism has not been fully elucidated.
- Trial name
- NCT02810821
- Where
- China
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Shandong Provincial Hospital
Metabolic Syndrome X
Effects the Glycemic Index on Metabolic Risk Markers
Recent population studies have shown that the glycemic index (GI) of food products is positively associated with the risk of developing type 2 diabetes and cardiovascular disease (CVD).
- Trial name
- NCT00695825
- Testing
- Low GI+high GI, High GI+low GI
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Dyslipidemias
Efficacy and Safety of Pitavastatin/Ezetimibe in Dyslipidemia Patients With Metabolic Syndrome: An Observational Study
The purpose of this study is to evaluate the efficacy and safety of Pitavastatin/Ezetimibe tablets (a fixed-dose combination of Pitavastatin and Ezetimibe) in patients with dyslipidemia who also have metabolic syndrome in a…
- Trial name
- PIVOT (NCT07523971)
- Where
- South Korea
- Volunteers
- 10,000 people
- Sponsor
- JW Pharmaceutical
Prolactinoma, Insulin Resistance
Insulin Resistance in Women With Prolactinoma
Prolactin is suggested to influence insulin resistance, but scarce data is available on the metabolic profile of patients with prolactinoma.
- Conditions
- Prolactinoma, Insulin Resistance, Hyperlipidemia
- Trial name
- NCT00481299
- Where
- Brazil
- Volunteers
- 2,004 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Metabolic Syndrome, Insulin Resistance
EFFECTS OF OLEUROPEIN ON BLOOD PARAMETERS AND INFLAMMATORY MARKERS IN ADULTS WITH METABOLIC SYNDROME
The aim of this study is to determine the effect of 6 weeks supplementation of oleuropein on individuals diagnosed with metabolic syndrome.
- Conditions
- Metabolic Syndrome, Insulin Resistance, Obesity, Abdominal, Obesity
- Trial name
- NCT06673914
- Testing
- Control Group: Diet Group, Oleuropein and Diet Group
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Atlas University
Metabolic Syndrome, Obesity
Observational Cohort of Pancreatic Echo-endoscopy
Metabolic syndrome is defined by the presence of at least two of the following five criteria: abdominal perimeter> 94 cm in men, 80 cm in women, high triglycerides, low HDL cholesterol, HTA and hyperglycemia.
- Conditions
- Metabolic Syndrome, Obesity, Hepatic Steatosis
- Trial name
- OBELIX (NCT04226014)
- Testing
- Endoscopic ultrasound
- Where
- 5 sites in France
- Volunteers
- 97 people
- Sponsor
- Centre Hospitalier Saint Joseph Saint Luc de Lyon
Metabolic Syndrome
Effect of Stablor on Visceral Fat Loss in Patients With a Metabolic Syndrome
The purpose of the study is to evaluate the impact of the intake of a dietary supplement STABLOR™ on the change of the abdominal visceral fat mass in patients with a metabolic syndrome.
- Trial name
- NCT01755104
- Testing
- Stablor
- Where
- 2 sites in Canada, France
- Volunteers
- 118 people
- Sponsor
- Laboratoires Nutrition et Cardiometabolisme
Stroke, Myocardial Infarction
Insulin Resistance Intervention After Stroke Trial
The purpose of this study is to determine if pioglitazone is effective in preventing future strokes or heart attacks among non-diabetic persons who have had a recent ischemic stroke.
- Conditions
- Stroke, Myocardial Infarction, Diabetes
- Trial name
- IRIS (NCT00091949)
- Testing
- pioglitazone
- Where
- 183 sites in United States, Australia and 6 more
- Volunteers
- 3,876 people
- Sponsor
- Yale University
HIV, Metabolic Diseases
Study of Lifestyle Modification in HIV Lipodystrophy
This study is designed to determine the effects of an intensive lifestyle modification program in patients with HIV and Metabolic Syndrome.
- Trial name
- NCT00111358
- Testing
- Lifestyle Modification, No lifestyle modification
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Massachusetts General Hospital
PCOS, Insulin Resistance
Effect of Bromocriptine on Insulin Resistance in Polycystic Ovarian Syndrome - A Pilot Study
The primary aim of this study is to determine the effect of dopamine agonist therapy on insulin resistance in lean vs. obese women with polycystic ovary syndrome.
- Trial name
- PCOS-Pilot (NCT02133755)
- Testing
- Bromocriptine
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- IWK Health Centre
Metabolic Syndrome
Exercise Training and Respiratory Muscle Training in Individuals With Metabolic Syndrome(METS)
The study will be conducted on individuals with Metabolic Syndrome. There are many studies showing that aerobic exercise provides significant improvements in waist circumference, fasting glucose, high-density lipoprotein…
- Trial name
- METS (NCT05413434)
- Testing
- exercise, inspiratory muscle training
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Hacettepe University
Metabolic Syndrome
Parenting Intervention and Metabolic Syndrome
This study aimed to test the effect of a parenting intervention on metabolic syndrome in African American youth. The investigators hypothesized that a parenting intervention would produce reductions in metabolic syndrome…
- Trial name
- NCT03139214
- Testing
- Parenting Intervention
- Volunteers
- 391 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Post-prandial Glycaemic Response, Satiety
Effect of Peas in Muffins on Blood Glucose and Appetite Control
This study is part of a group of studies whose overall goal is to accurately define the physiochemical and structural effects of pea varieties and relate these to blood glucose attenuation and appetite related sensations in…
- Trial name
- PEA3 (NCT03306706)
- Testing
- Whole pea muffins, Split pea muffins, Wheat muffins
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- St. Boniface Hospital