Clinical trials: Insulin Resistance Syndrome
Metabolic Syndrome
A Study on the Effects of Nutritious Mushrooms in Adults With Metabolic Syndrome
Obesity, characterized by an increase in body weight that results in excessive fat accumulation, is a global health problem. Recently, it has also been shown that obesity is associated with low-grade chronic systemic inflammation…
- Trial name
- NCT04081818
- Testing
- Nutritious Mushrooms
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Harokopio University
Cardiovascular Syndrome, Metabolic
Personalized Concurrent Exercise for Cardiovascular Risk Control and Fitness in Adults
Aim: To determine the efficacy of a personalized concurrent exercise prescription guide combined with pharmacological treatment compared to pharmacological treatment alone in controlling cardiovascular risk factors and physical…
- Trial name
- NCT06509282
- Testing
- Concurrent training
- Where
- Chile
- Volunteers
- 39 people
- Sponsor
- Universidad San Sebastián
Overweight, Hypertriglyceridemic Waist
Characterization of the Metabolic Fate of an Oral Arginine Form
The purpose of this study is to compare the metabolic fate of two oral forms of L-Arginine in healthy subjects featuring metabolic syndrome related risk factors
- Trial name
- NCT02352740
- Testing
- A form Arginine, B form Arginine
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Metabolic Syndrome
Mechanisms by Which Strength Training Ameliorates the Metabolic Syndrome
Prevention and treatment strategies for diabetes use exercise as the cornerstone. Even though endurance training and strength training both improve insulin resistance, strength training may be better suited for persons at risk…
- Trial name
- NCT00727779
- Testing
- strength training
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- East Tennessee State University
Prediabetic State, Obesity
Pancreatic Islet Function, Insulin Sensitivity, and Chronic Complications in Pre-Diabetes
We, the investigators at National Taiwan University Hospital, want to compare patients' islet cell function, insulin sensitivity and risk of chronic complications with normal subjects.
- Conditions
- Prediabetic State, Obesity, Metabolic Syndrome X
- Trial name
- NCT00172796
- Where
- Taiwan
- Sponsor
- National Taiwan University Hospital
Metabolic Syndrome
Lifestyle-related Early Detection and Intervention for Older Adults & Elderly at Risk for Metabolic Syndrome
In GATEKEEPER intervention, Big Data Analytics techniques will be exploited to address risk stratification and early detection, based on lifestyles analysis including: pattern recognition for the improvement of public health…
- Trial name
- GATEKEEPER (NCT05031299)
- Testing
- Standard care, Health-promotion application for self-management, Wearables and devices
- Where
- 2 sites in Greece
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Metabolic Disease
Efficacy of Laflavon in Lowering Triglycerides and Raising High-Density Lipoprotein (HDL)
A trial of LaFlavon in Patients with Metabolic Syndrome to Evaluate its Effectiveness in Lowering Triglycerides and Raising High-Density Lipoprotein (HDL).
- Trial name
- LaFlavon (NCT01286909)
- Testing
- LaFlavon
- Where
- Lebanon
- Volunteers
- 40 people
- Sponsor
- Omicron Pharmaceuticals
Metabolic Syndrome, Insulin Resistance
High-intensity Interval, Low Volume Training in Metabolic Syndrome
The primary objective of the study is to compare the efficacy of an intervention with high-intensity interval, low volume training (HIIT-LV) or continuous aerobic exercise (CAE) on insulin resistance, insulin sensitivity and…
- Trial name
- Intraining-MET (NCT03087721)
- Testing
- HIIT-LV, CAE
- Where
- Colombia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Hypertension, Metabolic Syndrome
Comprehensive Lifestyle Modification for Patients With Hypertension and Metabolic Syndrome: a Multicenter Randomized Controlled Trial
Different forms of diet, e.g. Mediterranean diet, DASH diet, or fasting, have demonstrated efficacy in reducing elevated blood pressure.
- Trial name
- NCT02099968
- Testing
- Comprehensive Lifestyle Modification, Standard Lifestyle Modification / modified DASH
- Where
- 2 sites in Germany
- Volunteers
- 145 people
- Sponsor
- Universität Duisburg-Essen
Metabolic Syndrome, Obesity & Overweight
Effect of Empagliflozin on Metabolic Outcomes in Adults Living With HIV Receiving Dolutegravir-Based Therapy
We investigate the role of empagliflozin in the treatment of obesity in PLWH.
- Conditions
- Metabolic Syndrome, Obesity & Overweight, HIV (Human Immunodeficiency Virus)
- Trial name
- NCT07336797
- Testing
- Empagliflozin (oral)
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Abdelrahman Mahmoud
Atherosclerosis, Metabolic Syndrome
Risk Factor Analysis for Coronary Atherosclerosis Measured by MDCT
Coronary MDCT (multi-detector computed tomography) has been useful screening imaging modality for the coronary artery disease. Recently, novel adipokines and hepatokines as well as various inflammatory markers have been known as…
- Trial name
- NCT01589224
- Where
- South Korea
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Korea University
Sepsis
The Degree, Duration and Frequency of Insulin Resistance in Non-operated Patients With Sepsis
Surgery induces insulin resistance lasting for 2-3 weeks. We wanted to elucidate if stress-metabolic, medical conditions carry the same effect.
- Trial name
- NCT04969159
- Testing
- no intervention
- Where
- Denmark
- Volunteers
- 18 people
- Sponsor
- Jens Rikardt Andersen
Menopause, Metabolic Syndrome
Lacto-ovo-vegetarian Diet Riched in Omega-3 Fatty Acids in Menopausal Women
Healthy lifestyle, based on healthy diet and exercise, is a key factor to prevent the most common menopausal disorders and chronic diseases to which women are more exposed during this life stage.
- Conditions
- Menopause, Metabolic Syndrome, Hepatic Steatosis
- Trial name
- NCT02816814
- Testing
- Diet rich in omega-3 fatty acids, Diet with extra virgin olive oil
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Sedentary, Cardiometabolic Syndrome
Effect of Interrupting Sedentary Time With Different Frequencies of Physical Activity on Cardiometabolic Risk Factors
The knowledge gap on sedentary behavior and sedentary breaks includes whether detrimental effects of sedentary behavior can be fully attenuated by 1.) sedentary breaks 2.) physical activity or 3.) both combined.
- Conditions
- Sedentary, Cardiometabolic Syndrome, Physical Activity
- Trial name
- NCT05622006
- Testing
- Sedentary breaks
- Where
- Norway
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Metabolic Syndrome
Early Vascular Wall Changes by Magnetic Resonance Imaging (MRI) in Metabolic Syndrome Versus Metabolically Normal Pre-Menopausal Women: A Pilot Study
The purpose of this study is to compare the vascular permeability of blood vessel walls (of the carotid artery) in pre-menopausal women who have metabolic syndrome (syndrome of having at least 3/5 following features- increased…
- Trial name
- NCT01068535
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Washington
Metabolic Syndrome, Gastric Cancer
Omentectomy for Metabolic Syndrome in Gastric Cancer Patients
Many features of the metabolic syndrome are associated with insulin resistance. And, metabolic syndrome and insulin resistance are related to visceral obesity.
- Trial name
- NCT02641925
- Testing
- Omentum preserving, Total omentectomy
- Where
- 3 sites in South Korea
- Volunteers
- 60 people
- Sponsor
- Keimyung University Dongsan Medical Center
Metabolic Syndrome
Hämeenlinna Metabolic Syndrome Research Program: Effects of Rapeseed Oil on Serum Lipids and Platelet Function
In this study, the effects of dietary intake of cold-pressed turnip rapeseed oil (CTPRO) and milk fat are compared in men with metabolic syndrome having already participated in HMS-02 study.
- Trial name
- HMS-03 (NCT01119690)
- Testing
- Cold-pressed turnip rapeseed oil (CTPRO), milk fat
- Where
- 4 sites in Finland
- Volunteers
- 43 people
- Sponsor
- Kanta-Häme Central Hospital
Diabetes Mellitus, Non-alcoholic Fatty Liver Disease
Transplantation of Microbes for Treatment of Metabolic Syndrome & NAFLD
Non-alcoholic fatty liver disease (NAFLD) occurs when excess fat is deposited in the liver. Almost all patients also have obesity and insulin resistance (the inability of the body to effectively use insulin).
- Trial name
- FMT (NCT02496390)
- Testing
- Autologous, Allogeneic
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Heart Failure, Cardiometabolic Syndrome
Hyperpolarized MR Imaging with Carbon-13 Pyruvate in the Human Body
Positron emission tomography with 18F fluorodeoxyglucose (FDG) is the conventional imaging technique to provide information regarding tissue glucose uptake and has been highly clinically successful.
- Conditions
- Heart Failure, Cardiometabolic Syndrome, Cancer Diagnosis, Cardiovascular Diseases
- Trial name
- POLARIC-13 (NCT06645691)
- Testing
- Hyperpolarized 13C-pyruvate
- Where
- Singapore
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Heart Centre Singapore
Heart Diseases, Type 2 Diabetes
Effectiveness of Tele-exercise Training on Cardiorespiratory Fitness in Patients With Cardiometabolic Multimorbidity
This trial aimed to assess whether assumed increase in physical activity after tele-exercise training can improve cardiorespiratory fitness of patients with cardiometabolic multimorbidity.
- Conditions
- Heart Diseases, Type 2 Diabetes, Metabolic Syndrome, Coronary Artery Disease
- Trial name
- NCT05245110
- Testing
- tele-exercise training
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Tri-Service General Hospital (TSGH)