Clinical trials: Intense Exercise
Hypertension,Essential, Exercise Activity
Effect of High-Intensity Interval Training Compared to Hydrochlorothiazide on Ambulatory Blood Pressure
The number of persons with hypertension is increasing and with it the number of related cardiovascular events and related functional or cognitive declines.
- Trial name
- DIISCCO (NCT04103411)
- Testing
- 24h-Ambulatory Blood Pressure
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Anil Nigam
Exercise Training, Physical Activity
Histamine H1/H2 Receptors and Training Adaptations
Exercise training is beneficial for both health and performance. Histamine has been shown to be involved in the acute exercise response.
- Trial name
- NCT04450134
- Testing
- Lactose, Fexofenadine Hydrochloride, Famotidine
- Where
- Belgium
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University Ghent
Cognitive Decline
Exercise Adherence and Cognitive Decline
The purpose of this study is to conduct a small-scale test of a goals-based program to help people to exercise more and learn what people like or don't like about the procedures.
- Trial name
- MOVE (NCT06769022)
- Testing
- Goal Setting and Exercise Intensity Intervention
- Where
- 3 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Schizophrenia
Acute Psychological Effects of High Intensity Exercise With Schizophrenia
The purpose of this study is to study the acute psychological effects in patients with schizophrenia after one session of high intensity exercise.
- Trial name
- NCT01310998
- Testing
- High intensity exercise
- Where
- Norway
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Baro-reflex Sensitivity, Heart Rate Variability
Low Intensity Exercise in Different Normobaric/Hypobaric Normoxic/Hypoxic Conditions.
The main goal of this project is to investigate how low intensity cycling exercise (1.5W/kg, for 6 minutes) influences cerebral functions, such as: Cerebral blood flow, oxygenation, and other physiological variables in different…
- Conditions
- Baro-reflex Sensitivity, Heart Rate Variability, EEG, Microstates, Cerebral Blood Flow Regulation
- Trial name
- Hypoxia (NCT03439202)
- Testing
- Hypoxia
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fliegerärztliches Institut
Chronic Low-back Pain, Exercise Therapy
Technology Supported High Intensity Training at Home for Persons With Chronic Low Back Pain
1. Background 1.1 Introduction Chronic low back pain (CLBP) is the most disabling musculoskeletal disorder worldwide4. Exercise therapy can improve CLBP, but effect sizes remain modest.
- Conditions
- Chronic Low-back Pain, Exercise Therapy, Telerehabilitation
- Trial name
- HIT-HOME (NCT05234008)
- Testing
- High intensity training at home
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Hasselt University
Greater Trochanteric Pain Syndrome
Effectiveness of High Intensity Laser Therapy in Patients With Greater Trochanteric Pain Syndrome
Greater trochanteric pain syndrome causes pain on the outer side of the hip. This study examined whether adding high-intensity laser therapy to exercise improved hip pain and function more than exercise alone.
- Trial name
- HILT-GTPS (NCT07838935)
- Testing
- Exercise Program, High Intensity Laser Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Uşak University
Sexual Wellness, Aerobic Capacity
The Effect of Lemongrass on Aerobic Performance
The goal of this experimental study is to examine the influence of Lemongrass extract on aerobic training parameters following a 6-week training programme in males.
- Conditions
- Sexual Wellness, Aerobic Capacity, Exercise Efficiency
- Trial name
- NCT07195240
- Testing
- Active: Lemongrass
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Osteoarthritis, Knee
Efficacy of High-Intensity Laser Therapy in Early-Stage Symptomatic Knee Osteoarthritis
This randomized, double-blind, sham-controlled clinical trial evaluated the effectiveness of high-intensity laser therapy (HILT) in patients with early-stage symptomatic knee osteoarthritis.
- Trial name
- HILT-ESCOA (NCT07859878)
- Testing
- High-Intensity Laser Therapy (HILT), Standardized Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Ege University
Type 2 Diabetes Mellitus
BFR Walking for Insulin and Aerobic Improvement in Type 2 Diabetes
This clinical trial examines the impact of Blood-Flow Restriction Walk Training (BFRw) on insulin sensitivity and aerobic capacity in individuals with Type 2 Diabetes (T2D).
- Trial name
- BRAID (NCT06290947)
- Testing
- BFR Cuffs for Intervention Group, Standard Walking Training Program
- Where
- Palestinian Territories
- Volunteers
- 60 people
- Sponsor
- Arab American University (Palestine)
Cancer, Cancer Cachexia
Protein-rich Nutritional Therapy Combined With Time-efficient Exercise in Cancer Therapy
This study aims to evaluate the effects of a 12-week protein-rich individualized nutritional therapy combined with different time-efficient exercise programs on overall physical fitness (cardiorespiratory fitness and muscular…
- Conditions
- Cancer, Cancer Cachexia, Inflammation
- Trial name
- PROTECT (NCT04065815)
- Testing
- Resistance Training, WB-EMS, High-intensity interval training (HIIT)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Healthy
The SKyRoCKeT Study
The SKyRoCKeT Study (Surface-Knit and Reformulate CADENCE-Kids for Translation) will recruit a sex- and age-balanced sample of 360 young people 6-20 years of age to develop an integrative, physiologically-coherent…
- Trial name
- SKyRoCKeT (NCT05770817)
- Testing
- N/A: SKyRoCKeT is an observational study
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Charlotte
Adult Population
The Acute Effects of Caffeine on Exercise and Cognition
The effects of moderate intensity aerobic exercise and caffeine ingestion on cognition (more specifically working memory) in non-caffeine drinker and caffeine drinkers will be examined.
- Trial name
- AEC (NCT03400423)
- Testing
- Caffeine, Moderate Intensity Exercise
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Achilles Tendinopathy
The Effect of Loading Speed and Intensity During Exercise on the Immediate Structural Changes in the Achilles Tendon
Aim: To assess the influence of loading speed and intensity during eccentric heel drop exercise on the immediate changes in Achilles tendon thickness and stiffness in healthy controls.
- Trial name
- NCT06057779
- Testing
- Slow and heavy exercise therapy, Slow and light exercise therapy, Fast and heavy exercise therapy
- Where
- Belgium
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Overweight and Obesity, Body Weight Changes
FatMax Training on Metabolic and Epigenetic Parameters
Exercise is an essential pillar for the health of all individuals, as it contributes to physical, mental, and emotional well-being.
- Trial name
- NCT06553482
- Testing
- FatMAx training intervention, FatMax and physical endurance exercise intervention, Control
- Where
- Mexico
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Breast Cancer
Health Benefits of HIT for Breast Cancer Patients
Treatment of cancer patients should not only involve removing the cancer, but should also focus on maintaining good health and well-being and quality of life.
- Trial name
- NCT03176888
- Testing
- Reduced-exertion, high-intensity interval training (REHIT), Cognitive behavioral therapy (CBT)
- Where
- United Kingdom
- Sponsor
- University of Stirling
Exercise-induced Muscle Soreness, Exercise-induced Joint Pain
Effects of Eggshell Membrane and Curcumin Extract Supplementation, Separately or Combined, on Recovery From Intense Exercise
Eggshell membrane and Curcumin supplementation prior to intense exercise may reduce inflammation, muscle and joint pain, and promote recovery.
- Conditions
- Exercise-induced Muscle Soreness, Exercise-induced Joint Pain, Exercise-induced Joint Stiffness, Exercise-induced Cartilage Turnover
- Trial name
- NCT07766720
- Testing
- NEM® brand eggshell membrane powder, curQ+® brand highly absorbable curcumin, NEM® plus curQ+® combination
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ESM Technologies, LLC
Menopause, Blood Pressure
Effect of Different Exercise Modalities on Cardiovascular and Cognitive Response in Postmenopausal Women
Menopause is a natural stage in female aging, increasing cardiometabolic risk and making cardio-neuro-vascular disease (CNVD) the leading cause of mortality in women over 60.
- Conditions
- Menopause, Blood Pressure, Cognitive Decline
- Trial name
- WOMEN-EX-MOD (NCT06533982)
- Testing
- High intensity interval exercise session, Isometric neuromuscular exercise session
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Poitiers
Obesity, Insulin Resistance
Effects of Obesity and Intensity of Exercise on Ghrelin Levels
This study is investigating the effect of different intensities of exercise on levels of the hormone, ghrelin. In addition, we will be examining the relationship between any exercise induced changes in ghrelin and insulin…
- Conditions
- Obesity, Insulin Resistance, Cardiovascular Risk Factor
- Trial name
- NCT04581980
- Testing
- Exercise
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Dialysis, Cardioprotection
Exercise Intensity
Patients receiving regular hemodialysis (HD) treatments are at a higher risk of cardiovascular events and death as HD can cause a decrease in the pumping of the heart during treatment called 'stunning'.
- Trial name
- NCT07119593
- Testing
- Intradialytic Cycling
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's