Clinical trials: Intense Exercise, open to volunteers
Affect and Exertion During and Post-exercise
Manipulating Exercise Intensity and Affective Responses for Cardiac Rehabilitation Program Acute Coronary Syndrome Patients
The goal of this clinical trial is to learn if pleasure-oriented exercise intensity manipulation increases physical activity (PA) behavior in patients who have suffered acute coronary syndrome during a cardiac rehabilitation…
- Trial name
- NCT07105943
- Testing
- Control, Experimental
- Where
- 2 sites in Portugal
- Volunteers
- 52 people
- Sponsor
- Instituto Politécnico de Leiria
Esophageal Cancer, Gastric Cancer (Diagnosis)
Exercise Training After Upper Gastrointestinal Cancer Surgery
This randomized controlled trial aims to determine the optimal exercise intensity for improving postoperative recovery in patients with upper gastrointestinal cancer.
- Conditions
- Esophageal Cancer, Gastric Cancer (Diagnosis), Upper Gastrointestinal Cancer
- Trial name
- NCT07561840
- Testing
- High-Intensity Interval Training (HIIT), Low-Intensity Continuous Training (LICT)
- Where
- 2 sites in Japan
- Volunteers
- 171 people
- Sponsor
- Kansai Medical University
Physical Activity, Exercise Training
Home-based Exercise and Physical Activity Intervention After Kidney Transplantation: Impact of Exercise Intensity
This multicentre two-phased RCT aims to evaluate implementation potential, cost-effectiveness, effectiveness, and the role of exercise intensity of a home-based exercise and physical activity intervention to improve de novo…
- Conditions
- Physical Activity, Exercise Training, Kidney Transplantation, Physical Fitness
- Trial name
- PHOENIX-Kidney (NCT06260579)
- Testing
- Exercise/physical activity
- Where
- 2 sites in Belgium
- Volunteers
- 147 people
- Sponsor
- KU Leuven
Urinary Continence, Urinary Incontinence
Trampoline-Induced Changes in Pelvic Structure and Continence
The goal of this clinical trial is to evaluate whether a short bout of high-intensity trampoline jumping induces urinary leakage or measurable changes in pelvic floor morphology in active females aged 18-40 who do not report…
- Conditions
- Urinary Continence, Urinary Incontinence, Urinary Incontinence (UI), Urinary Incontinence , Stress
- Trial name
- TRAM (NCT07183800)
- Testing
- Water
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Behavior
Acute Effects of Mat Pilates on Blood Pressure Response to Mental Stress in Higher Education Teachers
This study will investigate the acute effects of a moderate-intensity Mat Pilates session on blood pressure responses to mental stress in higher education teachers.
- Trial name
- NCT07872592
- Testing
- Acute Exercise, Control
- Where
- Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Federal University of Mato Grosso
Non-Small Cell Lung Cancer
Preoperative Structured Exercise Programme on Patients With Non-Small Cell Lung Cancer
INTRODUCTION: Lung cancer is among the leading cancers, and surgery has a major role in treatment. Patients diagnosed with Non-Small Cell Lung Cancer (NSCLC) who are eligible for surgical treatment have a high risk of…
- Trial name
- READY-LUNG (NCT07401056)
- Testing
- Prehabilitation (Structured Preoperative Exercise Programme)
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Hacettepe University
Lung Cancer (Diagnosis)
The Effects of Low Intensity Endurance Exercise on Improving Mitochondrial Function, Cell Bioelectrical Impedance Phase Angle, Fatigue and Quality of Life in Lung Cancer Patients With Cancer-related Fatigue
To conduct a randomized controlled trial (RCT) targeting lung cancer patients with cancer-related fatigue to achieve the following objectives: Objective 1: To investigate whether a low-intensity endurance exercise intervention…
- Trial name
- NCT07806682
- Testing
- Low-Intensity Endurance Continuous Exercise, Low-Intensity Endurance Interval Exercise
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Taipei Medical University
Cardiovascular Risk Markers, Postprandial Metabolism
Exercise Intensity and Postprandial Effects of Breaking Sedentary Behavior in Overweight Adults
The purpose of this study is twofold: (1) to determine whether breaking up prolonged sitting with aerobic or sprint cycling breaks reduces postprandial blood glucose, insulin, CRP, and blood pressure, which are established risk…
- Conditions
- Cardiovascular Risk Markers, Postprandial Metabolism, Exercise Physiology, Substrate Oxidation
- Trial name
- NCT07229963
- Testing
- Aerobic Exercise Intervention, Sprint Exercise Intervention, Sedentary Behaviour Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Exercise Induced Hypoalgesia, Circadian Rhythm
Pain Perception and Exercise-Induced Hypoalgesia Across Circadian Rhythms
The goal of this randomized crossover clinical trial is to investigate whether exercise-induced hypoalgesia (EIH) is influenced by circadian rhythm in healthy adults aged 18-40 years.
- Conditions
- Exercise Induced Hypoalgesia, Circadian Rhythm, Pain Perception, Healthy Participants
- Trial name
- NCT07290465
- Testing
- High-Intensity Functional Training (HIFT), Supervised Deep Breathing
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Medipol University
Stroke
HIT-Stroke Trial 2
People who had a stroke at least 6 months prior and who still have difficulty with walking will each be randomly assigned to receive either moderate or vigorous intensity walking exercise.
- Trial name
- HST2 (NCT06268041)
- Testing
- Moderate-Intensity Aerobic Training, High-Intensity Interval Training
- Where
- 3 sites in United States
- Volunteers
- 156 people
- Sponsor
- University of Cincinnati
Cardiovascular Diseases, Cardiac Rehabilitation
Threshold-Based Versus Range-Based Exercise Intensity Prescription in Cardiac Rehabilitation
Cardiac rehabilitation is an important part of the treatment of patients with cardiovascular disease. Supervised aerobic exercise improves physical fitness, functional capacity, and quality of life.
- Trial name
- T-REXI-CR (NCT07908810)
- Testing
- Threshold-Based Aerobic Exercise Intensity Prescription, Range-Based Aerobic Exercise Intensity Prescription
- Where
- 9 sites in Belgium
- Volunteers
- 230 people
- Sponsor
- Hasselt University
Mild Cognitive Impairment
Low-intensity Physical-cognitive Exercise and Cognitive Function
This study aims to examine the effects of low-intensity, combined physical-cognitive exercise on cognitive function of older people with mild cognitive impairment (MCI) and identify the mechanisms by which this exercise protocol…
- Trial name
- NCT06201533
- Testing
- combined physical-cognitive exercise
- Where
- Thailand
- Volunteers
- 64 people
- Sponsor
- Chiang Mai University
HFpEF - Heart Failure With Preserved Ejection Fraction
Cardiopulmonary Exercise Testing-based High-intensity Interval Training For Improving Heart Failure With Preserved Ejection Fraction
Cardiovascular-Kidney-Metabolic (CKM) Syndrome is a continuous clinical disease spectrum integrating cardiovascular, renal, and metabolic disorders.
- Trial name
- CPHIT-HFpEF (NCT07693049)
- Testing
- High-intensity interval training
- Where
- 13 sites in China
- Volunteers
- 192 people
- Sponsor
- Peking University Third Hospital
Weight Loss, Obese Children and Adolescents
The Therapeutic Effect of Different Exercise Intensities on Weight Loss in Obese Children
The incidence of childhood obesity is increasing, followed by metabolic diseases related to overweight and obesity in children. High intensity interval training (HIIT) has recently been shown to improve the body composition and…
- Trial name
- NCT06205563
- Testing
- high-intensity interval training, moderate intensity continuous training
- Volunteers
- 388 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Melanoma (Skin), Skin Cancer
High-Intensity Exercise and High-Fiber Diet for Immunotherapy Outcomes in Melanoma Patients: The DUO Trial
The purpose of this study is to determine whether high-intensity exercise and high-fiber diet are feasible and improve various health outcomes among participants with advanced melanoma receiving immunotherapy.
- Conditions
- Melanoma (Skin), Skin Cancer, Advanced Melanoma
- Trial name
- NCT06298734
- Testing
- Exercise Program, Diet Program
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Fred Hutchinson Cancer Center
Exercise-induced Myocardial Damage, Right Ventricular Diastolic Dysfunction
Effects of Exogenous Ketones on Acute Changes and Recovery of the Heart Muscle After Intense Exercise.
It is well known that scar tissue on the heart muscle can cause (life-threatening) arrhythmias. However, the exact cause of this scar tissue is not entirely clear.
- Trial name
- NCT06715748
- Testing
- Ketone Monoester (KE)
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Jessa Hospital
Prediabetes
Effects of Hourly Stair-Climbing Exercise Snacks on Metabolic and Vascular Health in Adults With Prediabetes
This study will examine whether very short bouts of stair climbing performed throughout the day can improve blood sugar control and cardiovascular health in adults with prediabetes.
- Trial name
- RISE UP (NCT07847684)
- Testing
- Hourly 3-Minute Light Walking Breaks, Hourly Stair-Climbing Exercise Snacks
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- St. Louis University
Pregnancy Related
The Effect of Long-Term Moderate Intensity Exercise During Pregnancy on Maternal and Fetal Cardiovascular System
The investigators aim to evaluate the effect of long-term moderate intensity physical activity during pregnancy in maternal and fetal cardiovascular system.
- Trial name
- NCT06572943
- Testing
- Moderate intensity physical activity
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- George Makrydimas
Aging, Cognitive Impairment
Effect of Gerofit Exercise on Cognition in Older Veterans
Over 50% of the Veterans enrolled for VA health care are over the age of 65. Dementia prevalence increases with age, and with the increase in the population of people ages 65 and older, the total number of people with dementia is…
- Conditions
- Aging, Cognitive Impairment, Physical Activity
- Trial name
- NCT06107842
- Testing
- Gerofit exercise, Health education
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Exercise
High-Intensity Functional Training (HIFT) vs Moderate-Intensity Continuous Training (MICT) in College Students
The purpose of this study is to compare two types of exercise programs in college students: high-intensity functional training and moderate-intensity continuous training.
- Trial name
- NCT07745270
- Testing
- High-Intensity Functional Training (HIFT), Moderate-Intensity Continuous Training (MICT)
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Miami