Clinical trials: Intensity Care
Perioperative Care
The Impact of Preoperative Statin Therapy and and Its Intensity on Postoperative and Mortality and Morbidity
Statins are among the most widely prescribed drugs worldwide, and their benefits in cardiovascular risk reduction are well established.
- Trial name
- STIMM (NCT07575737)
- Where
- 2 sites in Sweden
- Volunteers
- 70,000 people
- Sponsor
- Karolinska Institutet
Cardiac Catheterization
The Effect of Changing Angle of Bed on Pain Severity and Vascular Complications Among Cardiac Catheterization Patients
Care of CVD patients in Egypt is very complex and sensitive because of the high incidence and high mortality rate. In 2019, approximately 18.6 million deaths were attributed to CVD globally.
- Trial name
- NCT05539092
- Testing
- changing angle of bed
- Volunteers
- 82 people
- Sponsor
- Mansoura University
Pain, Chronic
Mobile-Based Contingency Management to Promote Daily Self-monitoring in Primary Care Patients
This project examines the efficacy and feasibility of contingency management (CM), delivered using a novel, fully automated CM app (DynamiCare Rewards), to promote daily self-monitoring of pain symptom severity and related…
- Trial name
- ProMPT (NCT03962491)
- Testing
- Daily Self-Monitoring Surveys + Contingency Management, Daily Self-Monitoring Surveys
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Virginia Commonwealth University
Alzheimer's Disease, Dementia
High Intensity Light Therapy in Alzheimer's Disease
The purpose of this study is to determine whether bright light improves the sleep, mood, and behavior of persons with Alzheimer's disease and related dementias (AD) who live in long-term care settings and, if so, to determine the…
- Trial name
- NCT00065689
- Testing
- high-intensity light therapy
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Shock, Aortic Valve Disease
Non-invasive Prediction of Fluid and Noradrenaline Responsiveness Using the Carotid Wave Intensity.
The goal of this observational study is to study a new method to compute ventricular-arterial coupling (VAC) in adult intensive care patients after cardiac surgery.
- Conditions
- Shock, Aortic Valve Disease, Coronary Artery Disease, Mitral Valve Disease
- Trial name
- VACC (NCT06197321)
- Where
- Netherlands
- Volunteers
- 120 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Delivery of Health Care
Evaluation of a Cross-sectional Coordinated, Severity Stepped, Evidence-based Care Model for Mental Disorders
This study evaluates a cross sectional, severity stepped, evidence-based care model for patients with mental disorders (RECOVER).
- Trial name
- RECOVER (NCT03459664)
- Testing
- RECOVER, Treatment as usual
- Where
- Germany
- Volunteers
- 905 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Urinary Incontinence, Quality of Life
Effect of HIFEM® Treatment of Urinary Incontinence in Women in Primary Care. A Randomized Controlled Trial
Urinary incontinence (UI) is a condition with involuntary leakage of urine. UI has a significant impact on health related quality of life, poorer sleep quality and sexual function, reduced participation in social and physical…
- Conditions
- Urinary Incontinence, Quality of Life, Menopause, Mental Health Issue
- Trial name
- NCT06485167
- Testing
- HIFEM- chair
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Lung Cancer
Determinants of Intensity of Care of Lung Cancer Patients With Organ Failure
Investigators will evaluate determinants of the patients' care type : palliative, medical or intensive care. The place of patient or family on care's decision will be noticed.
- Trial name
- CBP-DO (NCT01999621)
- Where
- France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Grenoble
Dermatitis, Atopic
A Multicenter Randomized Control Trial in Children With Moderate to Severe Atopic Dermatitis to Assess the Benefit of a Nurse-led One-to-one Education Program in Addition to Standard Care Compared to Standard Care Alone on the Long Term Control of Disease Severity at 6 Months
Atopic dermatitis is a chronic relapsing disease, which is highly prevalent in children (15%). Therapeutic patient education (TPE) has been recognized as a key priority topic for future AD research.
- Trial name
- EDUDA (NCT02634905)
- Testing
- Individual session therapeutic education, Phone Call
- Where
- 11 sites in France
- Volunteers
- 178 people
- Sponsor
- Nantes University Hospital
Fatigue, Chemotherapy
Prevalence, Severity and Determinants of Cancer-related Fatigue (CRF) in Asian Breast Cancer Patients
There is a paucity of studies that focus on the symptom burden of cancer patients in Singapore, particularly the clinical effects of cancer-related fatigue (CRF).
- Conditions
- Fatigue, Chemotherapy, Breast Cancer, Supportive Care
- Trial name
- NCT02304640
- Where
- Singapore
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Intensive Care Unit Delirium, Encephalopathy
Automating Delirium Severity in the ICU
The goal of this observational study is to develop a passive digital marker (PDM) for delirium severity and examine its performance in comparison to validated delirium severity tools in ICU patients >50 years of age.
- Conditions
- Intensive Care Unit Delirium, Encephalopathy, Delirium
- Trial name
- ADS-ICU (NCT06172491)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Mayo Clinic
Schizophrenia
Effect of Genotyping for CYP450 Polymorphisms Versus Intense Clinical Monitoring on Antipsychotic Drug Treatment
The purpose of this study is to determine whether genotyping for CYP2D6 and 2C19 polymorphisms or intense clinical monitoring of treatment and adverse effects improves the antipsychotic treatment in patients with schizophrenia.
- Trial name
- NCT00707382
- Testing
- (1) Genotyping for CYP4502D6 and 2C19 polymorphisms, (2) Intense clinical monitoring, (3) Control
- Where
- Denmark
- Volunteers
- 311 people
- Sponsor
- Gesche Jurgens
Acute Myeloid Leukemia
Reduced Intensity Conditioning Transplantation Versus Standard of Care in Acute Myeloid Leukemia
This study compares overall survival between patients with acute myeloid leukemia, who are in complete remission following initial treatment with chemotherapy and whose remission is maintained either with a transplantation of…
- Trial name
- NCT00342316
- Testing
- Reduced Intensity Conditioning Stem Cell Transplantation
- Where
- 25 sites in Australia, Canada and 7 more
- Volunteers
- 340 people
- Sponsor
- Vastra Gotaland Region
Intensive Care Units, Pediatric
Validation of Severity of Illness Scoring Systems in Paediatric Intensive Care Units in Canada
This is a study of the validation of severity of illness scoring systems in Paediatric Intensive Care Units (PICUs) in Canada.
- Trial name
- NCT00175799
- Where
- Canada
- Volunteers
- 10,000 people
- Sponsor
- University of British Columbia
Empathy, Sleep
PAIN Empathy Assessment in Sleep Deprived Emergency & Acute Care Clinicians
Cognitive Empathy is relevant in clinical practice and will be assessed based on the accuracy of pain recognition and the pain intensity evaluation in a computerised task using facial expressions.
- Conditions
- Empathy, Sleep, Pain
- Trial name
- PAIN-EASE (NCT05235035)
- Testing
- Night shift work
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Claude Bernard University
Preoperative Care, Colorectal Neoplasms
Assessing The Effectiveness of a Preoperative High Intensity Interval Training Programme In Older Colorectal Cancer Patients
The primary aim of this study is to determine whether an improvement in aerobic fitness, as judged by an increase in VO2peak, can be achieved within 31 days via HIT programme in a group of older, colorectal cancer patients.
- Conditions
- Preoperative Care, Colorectal Neoplasms, Aged, Exercise
- Trial name
- HITCa (NCT02188342)
- Testing
- HIT
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- University of Nottingham
Glioblastoma, Recurrent Glioblastoma
Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM
The brain is protected from any toxic or inflammatory molecule by the blood-brain barrier (BBB). This physical barrier is located at the level of the blood vessel walls.
- Conditions
- Glioblastoma, Recurrent Glioblastoma, GBM
- Trial name
- SONOBIRD (NCT05902169)
- Testing
- SonoCloud-9 (SC9), Carboplatin, Lomustine
- Where
- 56 sites in United States, Austria and 9 more
- Volunteers
- 560 people
- Sponsor
- CarThera
Nausea and Vomitting, Distension; Bowel
Reiki After Bariatric Surgery
The aim of this clinical trial was to determine whether Reiki administered to patients after bariatric surgery reduced abdominal distension, nausea and vomiting, and pain severity, and improved their comfort levels.
- Conditions
- Nausea and Vomitting, Distension; Bowel, Pain, Comfort
- Trial name
- NCT07887035
- Testing
- reiki
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- TC Erciyes University
Distress, PTSD
Scaling-up Psychological Interventions With Syrian Refugees in Switzerland
The current refugee crisis across the Middle East and Europe has large effects on individual refugees' psychological well-being, as well as on the healthcare systems of countries hosting refugees.
- Conditions
- Distress, PTSD, Anxiety, Depression
- Trial name
- STRENGTHS_CH (NCT03830008)
- Testing
- Problem Management Plus
- Where
- Switzerland
- Volunteers
- 59 people
- Sponsor
- University of Zurich
Thirst
Palliation of Thirst in ICU Patients
Patients in Intensive Care Units are often extremely thirsty due to their medicines, illness, treatments or medicines that they receive.
- Trial name
- NCT01015755
- Testing
- combined therapy treatment
- Where
- United States
- Volunteers
- 353 people
- Sponsor
- University of California, San Francisco