Clinical trials: Intensive Care Medicine
Tongue Edema, Tongue Enlarged
Tongue Edema Caused by Intubation Tube in Intensive Care Unit Patients
Tongue edema (TE) is an enlargement of the tongue that can be noticed with the naked eye and protrudes from the mouth. Endotracheal intubation tube, which can exert high pressure on the tongue for a long time, may cause TE.
- Conditions
- Tongue Edema, Tongue Enlarged, Mechanical Ventilation Complication, Intubation Complication
- Trial name
- NCT05249738
- Testing
- Measuring tongue cross-sectional area by submental ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Selcuk University
Diaphragm Ultrasound, Intensive Care Unit
The Value of Diaphragmatic Ultrasound in Non-invasive Oxygen Therapy
In this study, a single-center, prospective, observational study was adopted to set the cut-off values of diaphragmatic ultrasound results and arterial blood gas results，with the choice of non-invasive oxygen therapy as the gold…
- Trial name
- NCT04355559
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Chinese PLA General Hospital
Liver Cirrhosis, Viral Pneumonia
Liver Cirrhosis Patients With Invasive Pulmonary Aspergillosis: in Depth Understanding Clinical Host Risk Factors
Invasive pulmonary aspergillosis (IPA) is a life-threatening fungal infection of the respiratory system, caused by a specific fungus called Aspergillus species.
- Conditions
- Liver Cirrhosis, Viral Pneumonia, Fungal Infection, Invasive Pulmonary Aspergillosis
- Trial name
- LIVERIPA (NCT07238114)
- Where
- Belgium
- Volunteers
- 450 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Type II Diabetes, Cardiovascular Disease
Intensive Discharge Intervention in Diabetes
The goal of this study is to design and implement an intensive discharge intervention for inpatients with type 2 diabetes and cardiovascular disease, and determine the effects of the intervention on post-discharge insulin…
- Trial name
- IDID (NCT02122926)
- Testing
- Intensive discharge intervention
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Brigham and Women's Hospital
Vasoplegia
Midodrine for the Early Liberation of Vasopressor Support in the ICU (LIBERATE Multi-Site)
Vasopressors are medications that are given intravenously to increase the blood pressure of patients with illnesses that cause dangerous blood pressure drops.
- Trial name
- NCT05058612
- Testing
- Midodrine
- Where
- Canada
- Volunteers
- 870 people, healthy volunteers welcome
- Sponsor
- University of Alberta
SARS-CoV-2, Coronavirus
Personalized Health Education Against the Health Damage of Novel Coronavirus (COVID-19) Outbreak in Hungary
The additional effect of personalized health education compared to general education following the internationally accepted principles will be evaluated in the prevention of the serious course of the novel coronavirus infection.
- Conditions
- SARS-CoV-2, Coronavirus, COVID-19, 2019-nCoV
- Trial name
- PROACTIVE-19 (NCT04321928)
- Testing
- Personalized health education, General health education
- Where
- Hungary
- Volunteers
- 449 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Fever, Hyperthermia
The Fever and Antipyretic in Critically Illness Evaluation Study
The purpose of this multination multicenter observational study is to determine the impact of fever and antipyretic on outcomes in critically ill patients.
- Trial name
- FACE (NCT00940654)
- Testing
- Antipyretic therapy
- Where
- 2 sites in Japan, South Korea
- Volunteers
- 1,426 people
- Sponsor
- Japanese Society of Intensive Care Medicine
Transportation of Patients, PET / CT
To Evaluate Transport Safety Between Different Scanning Methods for Patients in the Intensive Care Unit (ICU)
The goal of this study is to assess how safe it is for critically ill patients in the Intensive Care Unit (ICU) to undergo a PET scan. A PET scan is a type of medical imaging used to help determine why a patient is sick.
- Conditions
- Transportation of Patients, PET / CT, Intensive Care Medicine
- Trial name
- CASA (NCT06912464)
- Where
- Netherlands
- Volunteers
- 208 people
- Sponsor
- University Medical Center Groningen
Acute Coronary Syndrome
Ticagrelor Removal Study Using CytoSorb® 300 mL Device During CPB in Patients Undergoing Emergent Cardiothoracic Surgery
The aim of CyTation is to demonstrate intra-operative removal of ticagrelor by CytoSorb® hemadsorption in patients on ticagrelor undergoing emergent cardiothoracic surgery requiring CPB, using platelet reactivity to adenosine…
- Trial name
- CyTation (NCT04625764)
- Testing
- Blood sampling and analysis
- Where
- 4 sites in Germany, Luxembourg
- Volunteers
- 6 people
- Sponsor
- CytoSorbents Europe GmbH
Shock, Septic
COMPACT 2 - COMbining Plasma-filtration and Adsorption Clinical Trial 2
The study objective is to clarify whether the application of high doses CPFA (coupled plasma-filtration adsorption) in addition to the current clinical practice is able to reduce hospital mortality in septic shock patients in…
- Trial name
- COMPACT-2 (NCT01639664)
- Testing
- High doses CPFA
- Where
- 13 sites in Italy
- Volunteers
- 115 people
- Sponsor
- Gruppo Italiano per la Valutazione degli Interventi in Terapia Intensiva
Patient Satisfaction
Patient Survey as a Tool to Quality Assurance and Quality Improvement 2024
One goal of the investigators of the Department of Anesthesiology and Intensive Care Medicine CCM/CVK, Charité - Universitätsmedizin Berlin is a continuous improvement in the quality of care to the patients.
- Trial name
- NCT06224231
- Where
- 2 sites in Germany
- Volunteers
- 624 people
- Sponsor
- Charite University, Berlin, Germany
Delirium
Retrospective Evaluation of Delirium Data From Previous Study Patients for Studies at the Clinic for Anesthesiology and Intensive Care Medicine CCM/CVK/CBF
Evaluation of several studies of the Clinic for Anesthesiology and Intensive Care Medicine CCM/CVK/CBF to create a register with the delirium data from anesthesiology study patients between 18 - 100 years.
- Trial name
- NCT05913531
- Where
- Germany
- Volunteers
- 5,000 people
- Sponsor
- Charite University, Berlin, Germany
Infection, Bacterial
Therapeutic Drug Monitoring of Anti-infectious Drugs in Intensive Care Unit
This research targets four anti-infectives commonly prescribed in intensive care: ceftazidime, cefepime, cefotaxime and meropenem, used for severe infections For patient hospitalized in intensive care unit , there is little or no…
- Trial name
- STP-ATB-REA (NCT03339869)
- Testing
- Blood sample
- Volunteers
- 180 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
PTSD, Post ICU Syndrome
Intensive Care Unit (ICU) Diary Project
Psychological morbidity in both patients and family members related to the intensive care unit (ICU) experience is an often overlooked, and potentially persistent, healthcare problem recognized by the Society of Critical Care…
- Trial name
- NCT04305353
- Testing
- Diary (blank journal) plus PTSD psycho-education, PTSD psycho-education alone
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Tulane University School of Medicine
Intensive Care Unit, Antibiotic Therapy
Therapeutic Monitoring of Antibiotics in Intensive Care Patients: a Cohort Study PopTDM-ICU
Intensive care patients are exposed to serious infections. Mortality linked to these infections remains high and antibiotic therapy treatment optimization is one of the key points of therapeutic success .
- Conditions
- Intensive Care Unit, Antibiotic Therapy, Pharmacokinetic
- Trial name
- NCT05367011
- Volunteers
- 2,500 people
- Sponsor
- Poitiers University Hospital
Prevalence of Burn-out Among Intensive Care Professionals
Evaluating the Effectiveness of the "Hello Bundle" Intervention in Reducing Burnout Among ICU Healthcare Professionals
Burnout among healthcare professionals in intensive care units (ICUs) is a prevalent concern with significant implications for both staff well-being and patient care outcomes.
- Trial name
- HELLO (NCT06453616)
- Testing
- Hello bundle
- Where
- Belgium
- Volunteers
- 7,300 people
- Sponsor
- Saint-Louis Hospital, Paris, France
Respiratory Insufficiency, Pressure Injury
Effectiveness of Platform-Based Lateralization Therapy in Reducing Interface Pressure Between The Patient And The Support Surface
Pressure injury (PI) is characterized as damage to the skin and/or underlying tissues resulting from sustained pressure or a combination of pressure and shear forces between the patient and the support surface.
- Conditions
- Respiratory Insufficiency, Pressure Injury, Intensive Care Medicine, ARDS
- Trial name
- PREVENT-ICU (NCT06819943)
- Testing
- Automated Lateral Rotation Therapy
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- University of Sao Paulo General Hospital
Influence of Nebulized Bronchodilatators on Selected, Electrophysiological Parameters
Nebulized Bronchodilators and Cardiac Repolarization
Patients of the ICU's often require bronchodilatory treatment due to bronchospasm caused by conditions like : acute respiratory distress syndrome (ARDS), chronic obstructive pulmonary disease (COPD) or asthma.
- Trial name
- NCT01714401
- Testing
- Salbutamol 2,5 mg, Salbutamol 5mg
- Where
- 2 sites in Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Gdansk
Drug Therapy
Safety Analysis of Antimicrobial Pharmacotherapy in Intensive Care Unit at Pediatric Hospital
Changes in the metabolic ability of cytochrome P-450 during child development can affect both bioavailability and elimination depending on the involvement of intestinal and hepatic metabolic processes.
- Trial name
- NCT04141657
- Testing
- Pharmacogenetic test
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- Anna Vlasova
Acute Kidney Injury, Hemodialysis
Comparison of Slow Efficiency Daily Dialysis (SLEDD) With Unfractionated Heparin Versus Citrasate in Critically Ill Patients.
The purpose of this study is to compare the feasibility, safety and efficacy of hemodialysis with unfractionated heparin compared to hemodialysis with Citrasate in Critically Ill Patients.
- Trial name
- NCT01228292
- Testing
- Unfractionated heparin, Citrasate
- Where
- Belgium
- Volunteers
- 250 people
- Sponsor
- University Hospital, Antwerp