Clinical trials: Intensive Care Neurological Disorder
Fatigue, Sleep Deprivation
Effect and Utilization of Protected Time Among Interns on Extended Duty-Hour Call Shifts
This study will test the feasibility and effectiveness of protected time for physicians in training during 30 hour shifts in a medical intensive care unit. The primary outcome will be fatigue.
- Conditions
- Fatigue, Sleep Deprivation, Depression
- Trial name
- NCT00983008
- Testing
- Protected time and Dedicated time
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Providence Health & Services
Immersive Virtual Reality, Discomfort
Effect of a Virtual Reality Program on Patient Comfort in the Surgical Intensive Care Unit
Admission to a surgical intensive care unit (ICU) following major surgery is associated with a number of discomforts, not only related to the disease itself, but also to the care provided or the ICU environment itself (lights…
- Conditions
- Immersive Virtual Reality, Discomfort, IPREA, Intensive Care Unit
- Trial name
- ZION (NCT06830369)
- Testing
- HypnoVR, usual health care
- Where
- France
- Volunteers
- 194 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Delirium
Prevention of Delirium With Light in the Intensive Care Unit
The purpose of this multicenter randomised controlled trial is to investigate if circadian light at the patients bedside (using Philips HealWell system, CE marked)significantly reduces prevalence of delirium in mechanically…
- Trial name
- PreDeLight-ICU (NCT01727375)
- Testing
- Circadian light
- Where
- Germany
- Sponsor
- Charite University, Berlin, Germany
Delirium, Sleep Fragmentation
Direct Noise Reduction in the Intensive Care Units (ICU) Using Earplugs and Noise Canceling Headphones
This study seeks to examine the effects of overnight noise reduction in critically ill patients who are receiving mechanical ventilation.
- Trial name
- NCT01343095
- Testing
- Foam Earplugs, Noise Canceling Headphones
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Wake Forest University
Critical Illness Polyneuropathies
Role of Anabolic Steroids on Intensive Care Unit-Acquired Weakness
The researchers intend to investigate possible anabolic effects of bi-weekly exogenous testosterone administration during intensive care unit (ICU) stay for up to 8 weeks.
- Trial name
- RAS-ICU (NCT03038919)
- Testing
- Testosterone cypionate, Standard nutrition and physical therapy at ICU
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Critical Illness, Intensive Care (ICU) Myopathy
Early Goal-Directed Nutrition in ICU Patients - EAT-ICU Trial
An increasing number of patients survive critical illness and intensive care, but describe having impaired physical function several years after discharge as a consequence of extensive loss of muscle mass.
- Conditions
- Critical Illness, Intensive Care (ICU) Myopathy, Muscle Wasting, Loss of Physical Function
- Trial name
- EAT-ICU (NCT01372176)
- Testing
- Early Goal-Directed Nutrition, ASPEN-guidelines
- Where
- Denmark
- Volunteers
- 203 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Persistent Ductus Arteriosus, Complication of Prematurity
The Preterm Infants' Paracetamol Study
Present randomized, controlled, double-blind trial investigates the efficacy and safety of early (<24 h) intravenous paracetamol therapy for pain medication in very small premature infants.
- Conditions
- Persistent Ductus Arteriosus, Complication of Prematurity, Pain or Discomfort in Intensive Care of Preterm Infants
- Trial name
- PreParaS (NCT01938261)
- Testing
- paracetamol, 0.45 % saline solution
- Where
- Finland
- Volunteers
- 120 people
- Sponsor
- University of Oulu
Neuromuscular Electrical Stimulation, Intensive Care Unit Acquired Weakness
Effects of Neuromuscular Electrical Stimulation on Muscle Mass and Strength in Critically Ill Patients After Cardiothoracic Surgery
The purposes of this study are 1) to determine whether neuromuscular electrical stimulation (NMES) is effective in preventing loss of muscle mass and strength and 2) to observe the time variation of MLT and strength from…
- Conditions
- Neuromuscular Electrical Stimulation, Intensive Care Unit Acquired Weakness, Muscle Wasting, Muscle Loss
- Trial name
- Catastim 2 (NCT02391103)
- Testing
- Compex 3 Professional (CefarCompex Medical AB) stimulator
- Volunteers
- 54 people
- Sponsor
- Medical University of Vienna
Traumatic Brain Injuries, Brain Injuries,Traumatic
Doppler Ultrasonography Parameters and Mortality in Traumatic Brain Injury
The purpose of this study is to find out whether blood flow measurements of the brain and neck arteries, obtained with bedside Doppler ultrasonography are associated with neurological outcome and survival in adult patients with…
- Trial name
- NCT07890259
- Testing
- Transcranial and Carotid Doppler Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Inonu University
Critical Illness, Delirium
Family Integration in Therapy Activities in the Intensive Care Unit: The FIT-ICU Feasibility Study
An ICU admission is stressful for not only patients but their families as well. Research has shown that involving family members during a loved one's ICU stay can be helpful for them, but there is not clear direction on the best…
- Trial name
- FIT-ICU (NCT06071793)
- Testing
- Family involvement
- Where
- 3 sites in Canada
- Volunteers
- 20 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Brain Damage
Transcranial Doppler and Quantitative Pupillometry as Neurological Prognostic Factors in Brain Damaged Patients Admitted to Intensive Care Unit
Transcranial Doppler is performed daily in Intensive Care Unit in brain damaged patients. For a few years now, the measurement of the photomotor reflex by quantitative Pupillometry has been routinely performed in Intensive Care…
- Trial name
- NCT04846738
- Testing
- Transcranial Doppler, Pupillometry.
- Where
- France
- Volunteers
- 73 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Brain Injuries
Cases With Traumatic and Non Traumatic Brain Damage Treated in the Intensive Care
Cases of traumatic and nontraumatic brain damage have high rates of morbidity and mortality. In this study of cases being treated in the ICU for a diagnosis of brain damage, it was aimed to evaluate the relationship between…
- Trial name
- NCT02475226
- Testing
- type of the brain injury
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Umraniye Education and Research Hospital
Pain, Traumatic Brain Injury
The NRC Dataset. Developing a Minimum Dataset for Multidisciplinary Rehabilitation: a Modified E-Delphi Study
Several rehabilitation datasets are presently in use for specific patient groups in England. The 'National Clinical Audit of Specialist Rehabilitation for patients with complex needs following major injury' (NCASRI) evaluated…
- Conditions
- Pain, Traumatic Brain Injury, Major Trauma, Multiple Sclerosis
- Trial name
- NCT06726135
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- ThomasCorbett
Critical Illness Myopathy
Rehabilitation Following Critical Illness
The principal research question to be answered by this study is whether an exercise based rehabilitative intervention following critical illness can generate improvements in exercise capacity and quality of life beyond current…
- Trial name
- NCT00976807
- Testing
- Pulmonary Rehabilitation
- Where
- 2 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Delirium
Dexmedetomidine to Lessen Intensive Care Unit (ICU) Agitation
The primary aim of the DahLIA trial is to determine, in patients with ICU-associated delirium and agitation who are otherwise pathophysiologically stable (as defined), the number of ventilator-free hours in the incident ICU…
- Trial name
- DahLIA (NCT01151865)
- Testing
- Dexmedetomidine
- Where
- 7 sites in Australia
- Volunteers
- 96 people
- Sponsor
- Austin Health
Traumatic Brain Injury
Observational Study of Cortical Spreading Depression in Human Brain Trauma
Since the primary damage from traumatic brain injury (TBI) is irreversible, the focus of medical management of TBI is preventing secondary injury that can be life-threatening and worsen patient outcome.
- Trial name
- COSBID-TBI (NCT00803036)
- Where
- 5 sites in United States, United Kingdom
- Volunteers
- 165 people
- Sponsor
- University of Cincinnati
Intensive Care Unit, Mortality
Analysis of the Evolution of Mortality in an Intensive Care Unit
The intensive care units is of the main components of modern healthcare systems. Formally, its aim is to offer the critically ill health care fit to their needs; ensuring that this health care is appropriate, sustainable, ethical…
- Conditions
- Intensive Care Unit, Mortality, Epidemiology, Respiration, Artificial
- Trial name
- NCT05261607
- Where
- Spain
- Volunteers
- 27,463 people
- Sponsor
- Hospital Universitario Getafe
Copd, Heart Failure
The Effect of Using Virtual Reality Glasses on Post-Care Pain and Comfort Level in Intensive Care Patients
The aim of this study is to determine the level of pain and comfort associated with the implementation of virtual reality prior to nursing care in patients undergoing treatment in the intensive care unit.
- Conditions
- Copd, Heart Failure, Intensive Care Unit Syndrome, Renal Failure
- Trial name
- NCT06923982
- Testing
- virtual reality, experimental group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Çankırı Karatekin University
Muscular Atrophy
Relation Between Bioelectrical Impedance Analysis (BIA) and CT-scan Analysis in the ICU
Aim of the present study is to determine whether muscle mass as assessed by bioelectrical impedance analysis correlates with and corresponds to muscle mass as assessed by CT scan analysis in critically patients admitted to the…
- Trial name
- ICUBIACT (NCT02555670)
- Testing
- BIA
- Volunteers
- 222 people
- Sponsor
- Amsterdam UMC, location VUmc
Coma, Heart Arrest
Predictive Outcome in Comatose Patients
Evaluating the prognosis of comatose patients after cardiac arrest (CA) in the intensive care unit (ICU) remains challenging. It requires a multimodal approach combining standardized clinical examination, serum biomarkers…
- Conditions
- Coma, Heart Arrest, Cardiopulmonary Resuscitation
- Trial name
- PRECOM (NCT05321459)
- Testing
- Neurological prognosis
- Where
- 7 sites in France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris