Clinical trials: Intensive Care Neurological Disorder
Stroke
Breakfast Group Interventions in Stroke Rehabilitation
Current evidence shows that many people living with stroke experience major problems with eating and drinking. We know that this can lead to malnutrition, dehydration, reduced muscle strength and depression.
- Trial name
- BISTRo (NCT05102812)
- Testing
- Breakfast Group Intervention
- Where
- United Kingdom
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Covid-19
Recovery After Critical Covid-19 Infection
The study focuses on the recovery of respiratory, cardiovascular and neurological/neuropsychological recovery after intensive care treatment for covid-19.
- Trial name
- RECOVID (NCT04864938)
- Where
- Finland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Disorders of the Autonomic Nervous System, Cardiovascular Abnormalities
Electrocardiographic Autonomic Function Measures in Mechanically Ventilated Patients
This research proposal has two main objectives. The first is to increase understanding of the underlying physiological interactions that occur between the cardiovascular, pulmonary, and ANS during transition between positive…
- Conditions
- Disorders of the Autonomic Nervous System, Cardiovascular Abnormalities, Respiratory Disorders
- Trial name
- NCT00844935
- Where
- United States
- Sponsor
- University of California, San Francisco
Critical Illness, Sleep Disturbance
Mobilisation in the EveNing to TreAt Delirium
Patients with severe illness require lifesaving treatment in intensive care units. Around a third of patients admitted to intensive care develop delirium. This is a severe state of confusion.
- Conditions
- Critical Illness, Sleep Disturbance, Mobility Limitation, Intensive Care Unit Delirium
- Trial name
- MENTAL (NCT05401461)
- Testing
- Evening mobilisation
- Where
- 2 sites in United Kingdom
- Volunteers
- 58 people
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Thoracic Diseases, Analgesia
Comparison of Tramadol, Pethidine and Morphine in the Treatment of Pain After Thoracic Surgery
Comparison of analgesic effects of tramadol, aldolan and morphine under thoracic surgery
- Trial name
- NCT06172920
- Testing
- Tramadol hydrochloride, Aldolan, Morphine hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Baskent University
Analgesia, Deep Sedation
Implementation and Evaluation of a Pediatric Nurse-driven Sedation Protocol in a PICU
Management of analgesia and sedation is an integral component of the medical care of a critically-ill child. Its role is to assure comfort and safety to a patient undergoing painful cares and technical procedures; it can also be…
- Trial name
- SEDATIDE (NCT02829710)
- Testing
- Nurse-driven sedation protocol
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Hospices Civils de Lyon
Brain Death, Organ Donation
Donation Network to Optimize Organ Recovery Study
This study consists in an cluster-randomized clinical trial involving near 60 Brazilian intensive care units (ICUs) with a high notification rate of potential donors of organs and tissues.
- Trial name
- DONORS (NCT03179020)
- Testing
- Checklist use, Usual care
- Where
- 63 sites in Brazil
- Volunteers
- 1,535 people
- Sponsor
- Hospital Moinhos de Vento
ICU Hospitalization, Sleep Deprivation
Impact of Sleep Deprivation on Malnutrition in ICU (Intensive Care Unit) Patients
Study Design This study is a prospective cohort design conducted at Zhongshan Hospital affiliated with Fudan University. It will involve systematic assessments of sleep quality, nutritional status, and associated clinical…
- Conditions
- ICU Hospitalization, Sleep Deprivation, Malnutrition Severe
- Trial name
- NCT07032441
- Testing
- PSG
- Volunteers
- 150 people
- Sponsor
- Shanghai Zhongshan Hospital
Delirium
Non-Invasive Eye Tracking for the Diagnosis of Delirium on ICU
In this trial, the investigators seek to demonstrate the feasibility of a system in continuously detecting 'inattention' as a subset of CAM-ICU in a small representative sample of patients in the Intensive Care Unit (ICU) at…
- Trial name
- CONfuSED (NCT04589169)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Sleep Disorder (Disorder), Critical Care
Electrophysiological Analysis of Gamma-Hydroxybutyrate-induced Sleep in Intensive Care Patients
In intensive care, sleep disturbances are extremely common and represent a major source of discomfort for patients. Restorative sleep is very limited.
- Trial name
- GAMMA-SLEEP (NCT07596342)
- Testing
- GHB
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Delirium, Postoperative Delirium
Projection of Visual Material on Postoperative Delirium in Patients Undergoing Cardiac Surgery
The aim is to evaluate the impact of visual projection of images of relatives or loved ones in patients undergoing cardiac surgery in the immediate postoperative period, and its influence on the incidence and development of…
- Conditions
- Delirium, Postoperative Delirium, Cardiac Surgery
- Trial name
- VisualMaterial (NCT05932394)
- Testing
- Projection of Visual Material on Postoperative Delirium in Patients Undergoing Cardiac Surgery, the usual unit treatment
- Where
- Spain
- Volunteers
- 105 people
- Sponsor
- University of Huelva
Myocardial Injury, Lung Injury
Neurogenic Myocardial and Lung Injury in SAH Patients
Up to this day, little is known whether the extent of brain damage in patients with SAH correlates with the degree neurogenic myocardial injury and neurogenic lung injury.
- Conditions
- Myocardial Injury, Lung Injury, Subarachnoid Hemorrhage
- Trial name
- NCT05408988
- Testing
- hs-TnT (high-sensitive cardiac troponin T) plasma concentration, CK-MB (creatine kinase myocardial band) plasma concentration, CPK (creatine phosphokinase) plasma concentration
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Medical University of Silesia
Neonatal Disorder
Soft Tissue Therapy in Managing Procedural Pain Among Neonates.
Effect of Soft tissue Therapy in managing Procedural Pain among neonates admitted in neonatal intensive care unit. This study focuses on the Procedural pain management with the help of Soft tissue manipulation which includes…
- Trial name
- NCT04309162
- Testing
- Soft tissue therapy
- Where
- India
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Asir John Samuel
Brain Death
Determining ICU Staffs Conceptions, Opinions, Views, Experiences and Reflection of Brain Death and Organ Donation
The study aims to gather information regarding the individual perceptions, opinions, beliefs, and conceptual understanding of healthcare professionals working in the intensive care units at the University Hospital Basel, the…
- Trial name
- DISCOVER (NCT06640088)
- Where
- Switzerland
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Delirium, Critical Illness
Driving Rehabilitation and Innovation for Evaluating Risk in Post-Intensive Care Unit Survivors
Older adults are at risk for ICU-acquired cognitive decline discernible from clinical, biological, and imaging- related changes in the brain following delirium and critical illness.
- Conditions
- Delirium, Critical Illness, Drive
- Trial name
- DRIVE-PICS (NCT05999903)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Baylor Research Institute
Postoperative Delirium, Intensive Care Psychiatric Disorder
Incidence and Risk Factors of PostopeRativE Delirium in ICU in China
Postoperative delirium (POD) is a common postoperative complication that can occur in patients of any age. POD brings great burden to patients and their families, as the following cognitive decline may persist for months to years…
- Trial name
- PREDICt (NCT03704324)
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Shanghai Zhongshan Hospital
Delirium
ORIC-I: Optimizing Recovery From Intensive Care: Mechanical Ventilation and Delirium
The purpose of this study is to determine if treating delirious intensive care unit patients with haloperidol improves mortality.
- Trial name
- NCT00300391
- Testing
- haloperidol
- Volunteers
- 40 people
- Sponsor
- University of Pittsburgh
Analgesia, Sedation
A Study Comparing Two Analgesia/Sedation Regimens, Remifentanil/Propofol Versus Sufentanil/Propofol In Mechanically Ventilated Intensive Care Patients Requiring Analgesia And Sedation.
This prospective, randomized, multicenter, open-label study will compare two analgesia-based regimens for sedation (remifentanil/propofol vs.
- Trial name
- NCT00421720
- Testing
- Sufentanil, Remifentanil
- Where
- 10 sites in Germany
- Volunteers
- 164 people
- Sponsor
- GlaxoSmithKline