Clinical trials: Intensive Care Patients
Intensive Care Ventilation
Pressure Support Ventilation With the Anesthetic Conserving Device
Sevoflurane inhalational anesthetic has got pulmonary effects such as bronchodilatation. These effects could be of interest in intensive care patients ventilated in pressure support ventilation mode.
- Trial name
- NCT01017744
- Testing
- Anesthetic Conserving Device
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Clermont-Ferrand
Pressure Sores, Intensive Care
The Effect of Antioxidants on the Immune Response and Wound Healing in Critically Ill Patients
The purpose of this study is to investigate whether the addition of omega-3 and antioxidants to nutritional support in critically ill patients in the intensive care unit influences the immune and anti-inflammatory systems and so…
- Trial name
- NCT00487097
- Testing
- Eicosapentanoic acid, docosahexaenoic acid
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Rabin Medical Center
Delirium, Agitation
A Comparison of Dexmedetomidine and Haloperidol in Patients With Intensive Care Unit (ICU)-Associated Agitation and Delirium
The purpose of the study is to determine whether dexmedetomidine is a more effective medication than haloperidol in the treatment of agitation and delirium in patients receiving mechanical ventilation in an intensive care unit.
- Conditions
- Delirium, Agitation, Ventilator Weaning, Respiration, Artificial
- Trial name
- Dex (NCT00505804)
- Testing
- dexmedetomidine, haloperidol
- Volunteers
- 20 people
- Sponsor
- Austin Health
Intensive Care Patients on a Ventilator
Safety of the Automatic Respiration Transfer System- Timer
The Israel Terminally Ill Law, 2005 allows patients who are terminally ill and ventilated to have their ventilator placed on a timer which at a specific time in the future stops the ventilator, maintains the patient on positive…
- Trial name
- Timer (NCT01735292)
- Testing
- Automatic Respiration Transfer System- Timer
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Hadassah Medical Organization
Intensive Care
Crystalloid Versus Hydroxyethyl Starch Trials
The aim of this study is to determine whether patients in the Intensive Care Unit who receive fluid resuscitation with either hydroxyethyl starch (a synthetic colloid solution) or saline (a salt solution), have an increased rate…
- Trial name
- CHEST (NCT00935168)
- Testing
- 6% Hydroxy-ethyl starch (130/0.4), Saline
- Where
- Australia
- Volunteers
- 7,000 people
- Sponsor
- The George Institute
Child Comfort, Morphine
Alfentanil Versus Sufentanil for Pain in Children During for Tracheal Suction
The main objective is to assess the efficacy of Alfentanil for pain in children treated by tracheal suction in pediatric intensive care units in France, compared to Sufentanyl, the current standard treatment.
- Conditions
- Child Comfort, Morphine, Intensive Care Units, Pediatric
- Trial name
- DOLOREAPEDIA (NCT01235637)
- Testing
- Alfentanil, Sufentanil
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Grenoble
Intensive Care Unit Days
Proactive Ethics Intervention to Improve Intensive Care Unit (ICU) Care
The primary aim of the study is to demonstrate the value of a preemptive approach to ethics consultation in an ICU. The investigators hope to answer the question: Will proactive ethics interventions by a skilled and experienced…
- Trial name
- PEI (NCT00996814)
- Testing
- Proactive Ethics Intervention
- Where
- United States
- Volunteers
- 386 people
- Sponsor
- California Pacific Medical Center Research Institute
Newborn Morbidity, Pain
Epidemiology of Painful Procedures in Neonates
Sick or premature neonates are exposed to frequent painful and stressful procedures during their stay in neonatal intensive care units.
- Conditions
- Newborn Morbidity, Pain, Procedures, Intratracheal Intubation
- Trial name
- EPIPPAIN (NCT01346813)
- Where
- 21 sites in France
- Volunteers
- 1,000 people
- Sponsor
- Hôpital Armand Trousseau
Mechanical Ventilation, Children
Pediatric Ventilatory Care in Finland 2010
This observational study includes questionnaires send to doctors in all units treating pediatric patients with mechanical ventilation in Finland.
- Conditions
- Mechanical Ventilation, Children, Neonates, Pediatric Intensive Care
- Trial name
- NCT01348295
- Testing
- Observation
- Where
- Finland
- Volunteers
- 210 people
- Sponsor
- University of Oulu
Delirium, Intensive Care Unit Syndrome
Influence of Light Therapy on Confusion in Patients at the Intensive Care Unit
Our purpose of this study is to determine whether bright light therapy is effective for reducing the incidence and the duration of delirium compared to the usual treatment in patients at the Intensive Care Unit.
- Trial name
- NCT01343433
- Where
- Netherlands
- Volunteers
- 70 people
- Sponsor
- Onze Lieve Vrouwe Gasthuis
Intensive Care, Blood Transfusion
Restrictive and Liberal Transfusion Strategies in Intensive Care
The most effective transfusion practice in critically ill ICU patients is unknown. Currently the data is unclear as to whether a liberal or restrictive transfusion policy is of most benefit to patients in the short and longer…
- Conditions
- Intensive Care, Blood Transfusion, Anemia
- Trial name
- RELIEVE (NCT00944112)
- Testing
- Restrictive RBC Transfusion, Liberal RBC Transfusion
- Where
- 6 sites in United Kingdom
- Volunteers
- 100 people
- Sponsor
- University of Edinburgh
Immobility and Weakness Associated With Long Intensive Care Unit Stays
Early Progressive Mobility in the CVICU: Assessing Current Status
The current study is proposed to assess the frequency and type of progressive mobility procedures currently performed in the CVICU The study will evaluate the type and frequency of progressive mobility orders, whether or not…
- Trial name
- NCT01295541
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Hill-Rom
Pneumonia, Intensive Care Unit
Effects of Isolated Rooms on the Prevalence of Hospital Acquired Pneumonia in a Respiratory ICU
This study will carry out in the ICU. Objectives of the study are to determine the frequency of HAP and the effect of isolated rooms on the frequency of pneumonia in the ICU.
- Trial name
- NCT01250691
- Testing
- ward-type ICU
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 532 people
- Sponsor
- Eskisehir Osmangazi University
Critical Illness, Intensive Care
Critical Illness Outcomes Study
We will test whether the way that an intensive care unit is organized can influence patient related outcomes such as mortality. We will test whether who works in the ICU, and how the ICU is managed will affect the care received…
- Conditions
- Critical Illness, Intensive Care, Intensive Care Unit
- Trial name
- CIOS (NCT01109719)
- Where
- United States
- Volunteers
- 6,000 people
- Sponsor
- National Institute of General Medical Sciences (NIGMS)
APACHE Scoring Systems, Intensive Care Units
The Study of Clinical Value of Acute Physiologic and Chronic Health Evaluation (APACHE) Scoring System in Medical Intensive Care Unit
Objective: To evaluate and compare the outcome predictive power of Acute Physiologic and Chronic Health Evaluation (APACHE) Ⅳ、Ⅲ、Ⅱ scoring systems for intensive ill patients in an independent medical intensive care unit (MICU)…
- Conditions
- APACHE Scoring Systems, Intensive Care Units, Outcome Prediction, Mortality
- Trial name
- NCT01162408
- Volunteers
- 450 people
- Sponsor
- Sun Yat-sen University
Consciousness Disorders, Communication
Analysis of Vital, Facial and Muscular Responses Front to Music or Message in Coma, Vegetative State or Sedated Patients
Objectives: (1) To check music or voice message influence on vital signs, facial expressions or muscular tonus of coma, vegetative or sedated patients; (2) To connect the existence of patient's responsiveness with the Glasgow…
- Conditions
- Consciousness Disorders, Communication, Intensive Care
- Trial name
- NCT01141790
- Testing
- Music and voice message
- Where
- Brazil
- Sponsor
- University of Sao Paulo
Smoking, Mechanical Ventilation
Effect of Daily Nicotine Patch Application on Mechanical Ventilation Weaning in Smoking Patients
Nicotine patches are frequently used in smoking patients during their stay in the ICU in order to avoid tobacco's weaning symptoms which are likely to interfere with mechanical ventilation weaning.
- Conditions
- Smoking, Mechanical Ventilation, Intensive Care
- Trial name
- NICOREA (NCT01104896)
- Testing
- Nicotine patch
- Where
- France
- Volunteers
- 600 people
- Sponsor
- University of Paris 5 - Rene Descartes
Critical Illness, Length of Stay
Advantages and Disadvantages of Long Term Sedation in Intensive Care Unit Patients
The purpose of the study is to determine whether sedation of the critical ill patient prolongs the time receiving mechanical ventilation.
- Conditions
- Critical Illness, Length of Stay, Respiration, Artificial, Intensive Care Units
- Trial name
- NCT00466492
- Testing
- Sedation or no sedation during mechanical ventilation
- Where
- Denmark
- Volunteers
- 140 people
- Sponsor
- Odense University Hospital
Anesthesia, Intensive Care
Pressure Course in the Tube Cuff During Swallowing
Leakage of fluid from the subglottic space to the lungs occurs along the longitudinal folds within the wall of endotracheal tube (ETT) cuffs.
- Trial name
- NCT00862797
- Testing
- pressure measurement during swallowing
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Freiburg
Analgesia, Sedation
Surgical Stress Index as a Tool for Monitoring Analgesia and/or Sedation in Critically Ill Patients
The hypothesis of the study is: Does the Surgical Stress Index (SSI) correlate with the Behavioral Pain Scale (BPS), the Ramsay Sedation Scale (RSS)and/or the Behavioral Pain Scale(BPV) and can therefore be used to monitor the…
- Conditions
- Analgesia, Sedation, Mechanical Ventilation, Pain
- Trial name
- NCT00789412
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital Schleswig-Holstein