Clinical trials: Intensive Care Unit Admission
Acute Respiratory Distress Syndrome, Inflammation
Dexmedetomidine to Improve Outcomes of ARDS in Critical Care COVID-19 Patients
A continuous infusion of Dexmedetomidine (DEX) will be administered to 80 patients admitted to Critical Care because of signs of Respiratory Insufficiency requiring non-invasive ventilation.
- Conditions
- Acute Respiratory Distress Syndrome, Inflammation, Dexmedetomidine, Cytokine Storm
- Trial name
- COVID-DEX (NCT04358627)
- Testing
- Dexmedetomidine Injectable Product
- Volunteers
- 80 people
- Sponsor
- Hospital Clinic of Barcelona
COVID-19
Immune Profiling of COVID19-patients Admitted to ICU
SARS-CoV-2 is the novel coronavirus responsible for COVID-19, coronavirus disease 2019. This new coronavirus was first detected in Wuhan, China in late December 2019.
- Trial name
- IMPROVISE (NCT04473131)
- Testing
- No intervention
- Where
- Qatar
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Cardiac Output, High, Cardiac Output, Low
Using Minimally Invasive Cardiac Output Data vs. Standard Care for Patients Emergently Admitted to the Intensive Care Unit Who Are Hemodynamically Unstable
The purpose of this study is to evaluate if the continuous availability of minimally invasive cardiac output data during treatment in the intensive care unit (ICU) for hemodynamic instability, in comparison to standard of care…
- Trial name
- NCT00354211
- Testing
- minimally invasive cardiac output system consisting of arterial line sensor and cardiac output bedside monitor (device)
- Where
- 3 sites in Finland, Switzerland
- Volunteers
- 392 people
- Sponsor
- Edwards Lifesciences
Platelets/Albumin and Aki
Platelets to Albumin Ratio for Prediction of Acute Kidney Injury in Patients Admitted to the Intensive Care Unit
To evaluate the role of platelet to albumin ratio to detect Acute kidney injury in patients admitted to intensive care
- Trial name
- NCT06554977
- Testing
- Laboratory
- Volunteers
- 140 people
- Sponsor
- Assiut University
Critical Illness, Intensive Care Unit Acquired Weakness
PRotEin Provision in Critical IllneSs
Rapid skeletal muscle wasting during critical illness had a detrimental impact on both short and long term outcomes following ICU admission.
- Trial name
- PRECISe (NCT04633421)
- Testing
- PRECISe protocol EN 8g protein/100kcal, PRECISe protocol EN 5g protein/100kcal
- Where
- 10 sites in Belgium, Netherlands
- Volunteers
- 935 people
- Sponsor
- Maastricht University Medical Center
Gastric Retention
the Effect of Abdominal Massage on the Gastric Residual Volume.
The goals of this randomized controlled trial are: 1. To determine the mean gastric residual volume in ICU admitted adult patients before and after intervention. 2.
- Trial name
- NCT06062381
- Testing
- Abdominal Massage
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- University of Health Sciences Lahore
Motor Delay, Premature Birth
Effects of a Physical Therapy Intervention on Motor Delay in Infants Admitted to a Neonatal Intensive Care Unit
Study Aims Pilot study: Due to the large recruitment goal and length of the project, the study team/PIs will evaluate the first cohort of 6-10 participants to refine study procedures and study-related materials.
- Conditions
- Motor Delay, Premature Birth, Intraventricular Hemorrhage, Hypoxic-Ischemic Encephalopathy
- Trial name
- NCT05568264
- Testing
- Physical Therapy intervention
- Where
- 3 sites in United States
- Volunteers
- 222 people
- Sponsor
- Shirley Ryan AbilityLab
Hemoperfusion, Multiorgan Failure
Hemoperfusion in Critical Patients With Septic Multiorgan Dysfunction Syndrome.
Low-level interventional clinical trial to evaluate the effectiveness and safety of extracorporeal support with hemoperfusion in critical patients with septic multiorgan dysfunction syndrome.
- Conditions
- Hemoperfusion, Multiorgan Failure, Sepsis
- Trial name
- NCT05044403
- Testing
- Extracorporeal support with haemoperfusion, Conventional treatment
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- Hospital Clinic of Barcelona
Adult Patients With Septic Shock Admitted in Intensive Care Unit
Remote Ischemic Postconditioning in Septic Shock
Septic shock is a leading cause of death worldwide despite intensive research efforts. Only a few interventions have been proven to be effective in improving patient-centered outcomes.
- Trial name
- RIPOST-sepsis (NCT07273942)
- Testing
- Remote ischemic conditioning, No intervention
- Where
- 23 sites in France
- Volunteers
- 720 people
- Sponsor
- Hospices Civils de Lyon
Bacterial Pneumonia
Cx611-0204 SEPCELL Study
The purpose of this randomised, multicentre, double-blind, placebo-controlled, phase Ib/IIa study is to assess the safety, tolerability and efficacy of eASCs (Cx611) administered intravenously as adjunctive therapy, therefore in…
- Trial name
- SEPCELL (NCT03158727)
- Testing
- Cx611
- Where
- 33 sites in Belgium, France and 4 more
- Volunteers
- 84 people
- Sponsor
- Tigenix S.A.U.
Body Temperature Changes
Effect of Probe Placement in Delivery Room on Temperature at the Admission of Premature Infants?
The aim of the study is to compare the effect of 3 different skin temperature placement probe in the case room on the admission temperature to the NICU in preterm infants.
- Trial name
- NCT02769468
- Testing
- The Back, Chest, Left Axilla
- Where
- Canada
- Volunteers
- 121 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Critically Ill
24 Hour Intensivist Coverage in the Medical Intensive Care Unit
The Hospital of the University of Pennsylvania's Medical ICU (MICU) is implementing a model of 24-hour intensivist staffing in September 2011.
- Trial name
- NCT01434823
- Testing
- Nocturnal coverage
- Where
- United States
- Volunteers
- 1,609 people
- Sponsor
- University of Pennsylvania
Perinatal and Neonatal Outcomes in Pregnancies With Type 2 Diabetes Mellitus (T2DM)
Antenatal Myo-inositol Supplementation in Pre-existing Diabetes
This feasibility pilot study aims to gather data that can guide the design of a larger, more comprehensive trial to establish the effects of myo-inositol supplementation on supporting healthy outcomes in pregnancies complicated…
- Trial name
- AMulet (NCT07241221)
- Testing
- Myo-inositol and folic acid supplement, Folic acid supplement
- Where
- Singapore
- Volunteers
- 182 people
- Sponsor
- National University Hospital, Singapore
Protein-Energy Malnutrition
Usefulness of Protein-enriched Infant Formula in Pediatric Intensive Care.
A multicenter prospective randomized controlled trial (RCT) will be performed in three hospitals. Patients meeting inclusion criteria will be randomly allocated to one of three enteral feeding formula with different protein…
- Trial name
- NCT03901742
- Testing
- Protein-enriched nutrition, High Protein-enriched Nutrition, Standard Enteral Nutrition
- Where
- 3 sites in Spain
- Volunteers
- 90 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Frailty, Mortality
Determining the Prevalence of Frailty and Evaluating Its Relationship With Mortality.
Covid-19 patients admitted to the intensive care unit of Selcuk University Hospital were included in the study. Clinical frailty score was given during admission to the intensive care unit.
- Conditions
- Frailty, Mortality, COVID-19
- Trial name
- NCT06330883
- Testing
- Prognosis
- Where
- Turkey (Türkiye)
- Volunteers
- 148 people
- Sponsor
- Selcuk University
Cardiac Disease, Cardiac Ischemia
Assessment of Patients Undergoing Cardiac Surgery and Admitted to the Intensive Care Unit
The objective of this study is to investigate the incidence of death and early postoperative complications, identify potential risk factors, and examine the demographic characteristics of patients and epidemiology of…
- Conditions
- Cardiac Disease, Cardiac Ischemia, Cardiac Valve Disease
- Trial name
- BraSIS-2 (NCT06154473)
- Testing
- Open heart surgery group., Percutaneous cardiovascular surgery group.
- Where
- Brazil
- Volunteers
- 528 people
- Sponsor
- Hospital Israelita Albert Einstein
Metabolic Acidosis, Acid-Base Imbalance
Frequency of Metabolic Acidosis in the Pediatric Intensive Care Unit
Metabolic acidosis is one of the most common acid-base disturbances encountered in critically ill children and often reflects underlying disease severity.
- Conditions
- Metabolic Acidosis, Acid-Base Imbalance, Critical Illness in Children
- Trial name
- NCT07803263
- Volunteers
- 140 people
- Sponsor
- Assiut University
Intensive Care Units, Pediatric
Validation of Severity of Illness Scoring Systems in Paediatric Intensive Care Units in Canada
This is a study of the validation of severity of illness scoring systems in Paediatric Intensive Care Units (PICUs) in Canada.
- Trial name
- NCT00175799
- Where
- Canada
- Volunteers
- 10,000 people
- Sponsor
- University of British Columbia
Preoperative Anesthesia Assesment
AI Assisted Preoperative Assessment for ASA Classification and ICU Admission
This prospective observational study evaluates the performance of artificial intelligence (AI) models in preoperative anesthesia assessment.
- Trial name
- NCT07783334
- Testing
- AI-assisted preoperative assesment
- Where
- Turkey (Türkiye)
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Respiratory Failure, Delirium
Delirium, Agitation/Sedation, Pain and Dyspnea in Respiratory Intensive Care Unit (NIVILIUM)
Non-Invasive Mechanical Ventilation (NIV) has been increasingly used in the treatment of acute respiratory failure. Notwithstanding failure rates still remains high, ranging from 5% to 60%.
- Conditions
- Respiratory Failure, Delirium, Agitation,Psychomotor, Pain
- Trial name
- NIVILIUM (NCT03880084)
- Testing
- Observation
- Where
- Italy
- Volunteers
- 92 people
- Sponsor
- University of Modena and Reggio Emilia