Clinical trials: Intensive Care Unit Survivors
Circadian Dysregulation, Sleep Fragmentation
Compromised Sleep and Circadian Health After Critical Illness: From Diagnosis to Prediction (CHRONOCRIT)
The intensive care unit (ICU) is recognizably detrimental to sleep and circadian health, and critical survivors frequently report the presence of alterations in this regard after hospital discharge.
- Trial name
- CHRONOCRIT (NCT05995132)
- Where
- Spain
- Volunteers
- 271 people
- Sponsor
- Institut de Recerca Biomèdica de Lleida
Cardiorespiratory Failure
Mobile Coping Skills Training to Improve Cardiorespiratory Failure Survivors' Psychological Distress
This is a pilot randomized clinical trial involving adult survivors of cardiorespiratory failure treated in intensive care units (ICUs) that is designed to test the acceptability, feasibility, and clinical impact of a coping…
- Trial name
- Blueprint (NCT04329702)
- Testing
- Coping skills training mobile app with call from CST therapist, Coping skills training mobile app only
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Duke University
Chronic Pain, Post Intensive Care Unit Syndrome
The Post-ICU Pain Study
BACKGROUND: ICU survivors may experience serious psychological, physical and cognitive impairments following ICU admission, collectively termed Post Intensive Care Syndrome (PICS).
- Conditions
- Chronic Pain, Post Intensive Care Unit Syndrome, Quality of Life, Pain Disorder
- Trial name
- PIP (NCT07180407)
- Where
- 4 sites in Denmark
- Volunteers
- 800 people
- Sponsor
- Zealand University Hospital
Unable to Sit-to-stand, ICU Survivor
Effect of Sit-to-Stand Intervention in the Intensive Care Unit Survivors
"Sit-to-stand" is key to independent living. For intensive care unit (ICU) survivors, failure to perform sit-to-stand results in bed-bound status, unable participating in important activities of daily living (ADLs) or…
- Trial name
- NCT04640441
- Testing
- Sit-to-stand Intervention
- Where
- Taiwan
- Volunteers
- 246 people
- Sponsor
- National Taiwan University Hospital
Critical Illness, Delirium
A Multi-Modal Combination Intervention to Promote Cognitive Function in Older Intensive Care Unit Survivors
Up to 25% of intensive care unit (ICU) survivors experience cognitive impairment comparable in severity to mild Alzheimer's disease and related dementias after hospital discharge.
- Conditions
- Critical Illness, Delirium, Cognitive Impairment, Cognitive Decline
- Trial name
- SLEEP-COG (NCT06411561)
- Testing
- SLEEP + COG, COG, SLEEP
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Washington
Post-Intensive Care Syndrome (PICS), Symptom Burden
Post-Intensive Care Syndrome and Associated Symptom Burden Among Danish ICU Survivors
The study aims to estimate the prevalence of post-intensive care syndrome (PICS) 12 months after ICU admission among adult ICU survivors in Denmark and to describe how this prevalence is distributed across the physical…
- Conditions
- Post-Intensive Care Syndrome (PICS), Symptom Burden, Intensive Care Unit (ICU) Patients
- Trial name
- PICAS-DK (NCT07373561)
- Volunteers
- 800 people
- Sponsor
- Zealand University Hospital
Critical Illness, Stress, Psychological
Virtual Reality-Based Transitional Care for ICU Survivors
This study aims to evaluate the effectiveness of a virtual reality (VR)-based transitional care program for adult survivors of intensive care unit (ICU) care.
- Conditions
- Critical Illness, Stress, Psychological, Intensive Care Units
- Trial name
- VRICU (NCT07482722)
- Testing
- Virtual Reality-Based Transitional Care
- Where
- 2 sites in Taiwan
- Volunteers
- 150 people
- Sponsor
- Mackay Memorial Hospital
Cardiorespiratory Failure
Optimizing a Mobile Mindfulness Intervention for ICU Survivors
This is a factorial experimental trial involving adult survivors of cardiorespiratory failure treated in intensive care units (ICUs) that is conceptualized as the Optimization Phase of a multiphase optimization strategy (MOST)…
- Trial name
- LIFT2 (NCT04038567)
- Testing
- Mobile mindfulness-based training
- Where
- 3 sites in United States
- Volunteers
- 247 people
- Sponsor
- Duke University
Chronic Fatigue Syndrome, Intensive Care Unit
Chronic Fatigue Etiology in Intensive Care Unit Survivors: the Role of Neuromuscular Function
Chronic fatigue is the most common and debilitating symptom in intensive care unit (ICU) survivors. Indeed, it has been widely reported that patients who stayed in ICU for prolonged periods report a feeling of tiredness for…
- Conditions
- Chronic Fatigue Syndrome, Intensive Care Unit, Muscle
- Trial name
- FatPostRéa (NCT03849326)
- Testing
- Questionnaires, blood test, Maximal effort test
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Gastroesophageal Reflux Disease, Critically Ill
Gastroesophageal Reflux Disease (GERD) Among ICU Survivors
Gastro-esophageal reflux disease (GERD) is a condition characterized by reflux of stomach contents causing troublesome symptoms and complications.
- Trial name
- NCT05193266
- Where
- India
- Volunteers
- 116 people
- Sponsor
- Sanjay Gandhi Postgraduate Institute of Medical Sciences
Stress Disorders, Post Traumatic, Anxiety
Preventing Post-traumatic Stress in ICU Survivors: A Pilot Randomized Controlled Trial of ICU Diaries
The main objective of the study is to test the feasibility of the ICU diaries intervention in the ICU. The investigators do not have sufficient power to detect differences in the hypotheses below, but will use the present pilot…
- Conditions
- Stress Disorders, Post Traumatic, Anxiety, Depression, Quality of Life
- Trial name
- NCT02067559
- Testing
- ICU Diary, Psychoeducation
- Where
- Canada
- Volunteers
- 59 people
- Sponsor
- University of Manitoba
ICU Hospitalization, Chronic Pain
Chronic Pain After Intensive Care Unit: Clinical Predictors
Thanks to medical advances, more patients now survive their stay in the Intensive Care Unit (ICU). However, many people who leave the ICU face long-term health problems, known as Post-Intensive Care Syndrome (PICS).
- Trial name
- NCT07117396
- Where
- Greece
- Volunteers
- 92 people
- Sponsor
- Attikon Hospital
Critical Illness, Cognitive Impairment
Optimal Timing of Computerized Cognitive Training for Older Intensive Care Unit Survivors
More than 60% of intensive care unit (ICU) patients are adults ages 60 and older, who are at high risk for ICU-acquired cognitive impairment.
- Conditions
- Critical Illness, Cognitive Impairment, Circadian Dysrhythmia, Intensive Care Unit Delirium
- Trial name
- OPTIMIZE (NCT05467410)
- Testing
- COG-AM, COG-PM
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Washington
Adult Patients, Intensive Care Unit
Functional Recovery Over the First Year After ICU Discharge
Intensive Care Unit Acquired Delirium (ICU-AD) and Intensive Care Unit Acquired Weakness (ICU-AW) are common in critically ill, mechanically ventilated adult patients.
- Trial name
- NCT04206306
- Where
- Taiwan
- Volunteers
- 407 people
- Sponsor
- National Taiwan University Hospital
Depression, Anxiety, Post Traumatic Stress Disorder
Effects of a Digital Diary on the Psychological Well-being of Former ICU Patients.
Previous research on the impact of a diary on mental symptoms of PICS, PICS-F, and quality of life in former ICU patients and their relatives has focused specifically on a paper diary.
- Conditions
- Depression, Anxiety, Post Traumatic Stress Disorder, Quality of Life
- Trial name
- DIPIC (NCT06237699)
- Testing
- Digital ICU diary
- Where
- 4 sites in Netherlands
- Volunteers
- 400 people
- Sponsor
- Erasmus Medical Center
Post-acute COVID-19 Syndrome, Long-COVID
Sociodemographic, Clinical, Quality of Life and Health Care Conditions in COVID-19 Survivors.
Sociodemographic, Clinical, Quality of Life, and Health Care Conditions After Hospital Discharge in Patients Who Required Admission to the Intensive Care Unit for COVID-19 at the Hospital Universitario Nacional Between April 2020…
- Conditions
- Post-acute COVID-19 Syndrome, Long-COVID, COVID-19, Long COVID
- Trial name
- NCT05185674
- Testing
- Exposure: Coronavirus disease 2019 (COVID-19)
- Where
- Colombia
- Volunteers
- 114 people
- Sponsor
- Javier Eslava
Intensive Care Unit Survivors, Informal Caregivers (Family and Friends)
Improving Psychological Distress Among Critical Illness Survivors and Their Caregivers
Patients who receive life support in intensive care units commonly suffer from persistent depression, anxiety, and post-traumatic stress disorder (PTSD) symptoms after discharge.
- Trial name
- NCT01983254
- Testing
- coping skills training, education program
- Where
- 4 sites in United States
- Volunteers
- 417 people
- Sponsor
- Duke University
Delirium, Critical Illness
Driving Rehabilitation and Innovation for Evaluating Risk in Post-Intensive Care Unit Survivors
Older adults are at risk for ICU-acquired cognitive decline discernible from clinical, biological, and imaging- related changes in the brain following delirium and critical illness.
- Conditions
- Delirium, Critical Illness, Drive
- Trial name
- DRIVE-PICS (NCT05999903)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Baylor Research Institute
Post-Intensive Care Syndrome (PICS), Critical Illness Recovery
I-WEAR: Evaluating Wearables and Health Summaries in ICU Survivors
This pilot study investigates the use of wearable health technology and bi-weekly digital health summaries in patients recovering from intensive care.
- Conditions
- Post-Intensive Care Syndrome (PICS), Critical Illness Recovery, Coronary Artery Disease
- Trial name
- I-WEAR (NCT07035106)
- Testing
- Wearable Health Monitoring, Digital Health Summary and Lifestyle Counseling
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Ludwig Boltzmann Gesellschaft
Intensive Care (ICU), Intensive Care Unit (ICU) Admission
Supply Induced Demand in Intensive Care Unit: a Retrospective Trial
Intensive Care Unit (ICU) represents a high-level healthcare and expensive resource in hospitals. The causes of hospitalization in critical care are therefore multiple, and over the years numerous prognostic scores have been…
- Conditions
- Intensive Care (ICU), Intensive Care Unit (ICU) Admission, Intensive Care Unit Survivors, SID
- Trial name
- NCT07768410
- Where
- Italy
- Volunteers
- 1,500 people
- Sponsor
- Saint Camillus International University of Health Sciences