Clinical trials: Intensive Care Ventilation
Respiratory Insufficiency, Pressure Injury
Effectiveness of Platform-Based Lateralization Therapy in Reducing Interface Pressure Between The Patient And The Support Surface
Pressure injury (PI) is characterized as damage to the skin and/or underlying tissues resulting from sustained pressure or a combination of pressure and shear forces between the patient and the support surface.
- Conditions
- Respiratory Insufficiency, Pressure Injury, Intensive Care Medicine, ARDS
- Trial name
- PREVENT-ICU (NCT06819943)
- Testing
- Automated Lateral Rotation Therapy
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- University of Sao Paulo General Hospital
Nutrition Disorders, Malnutrition
Isolated or Combined Use of NUTRIC Score and NRS-2002 to Predict Mortality in the Intensive Care Unit
The objective of this investigation was to assess the predictive capacity of the NUTRIC Score and NRS-2002, separately or combined, in forecasting hospital, 28-day and 3-month mortality in patients with respiratory failure…
- Conditions
- Nutrition Disorders, Malnutrition, Mortality
- Trial name
- NCT06115525
- Testing
- mNUTRIC score, NRS-2002
- Where
- Turkey (Türkiye)
- Volunteers
- 750 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Respiratory Failure
Use of Neurally Adjusted Ventilatory Assist in Infants Respiratory Failure
The present protocol will demonstrate the feasibility and efficacy of a newly developed mode of mechanical ventilation, Neurally Adjusted Ventilatory Assist, commonly known as NAVA.
- Trial name
- NAVA (NCT00603174)
- Testing
- neurally adjusted ventilatory assist (NAVA)
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- St. Justine's Hospital
ICU-acquired Weakness, Mechanical Ventilation
eCASH and Early Goal-Directed Mobilization to Prevent ICU-Acquired Weakness
This single-center, prospective, randomized controlled trial aims to evaluate whether an eCASH concept-based analgesia and sedation strategy combined with early goal-directed mobilization can reduce the incidence of intensive…
- Conditions
- ICU-acquired Weakness, Mechanical Ventilation, Critical Illness
- Trial name
- eCASH-EGDM (NCT07677488)
- Testing
- eCASH-Based Analgesia and Sedation Strategy Combined With Early Goal-Directed Mobilization, Routine ICU Nursing Care
- Where
- China
- Volunteers
- 70 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Post-intensive Care Syndrome, COVID-19
Clinical and Functional Characteristics of Patients Admitted for Severe COVID-19 Pneumonia
This research protocol aims to evaluate the impact of severe COVID-19 pneumonia requiring invasive mechanical ventilation (IMV) on health-related quality of life (HRQoL), functional capacity, muscle strength, and nutritional…
- Trial name
- EQOL-COVID (NCT06727474)
- Testing
- Health-Related Quality of Life (HRQoL) with EQ-5D-3L
- Where
- Argentina
- Volunteers
- 51 people
- Sponsor
- Hospital Nacional Profesor Alejandro Posadas
Respiratory Failure, Tracheostomy Complication
Ventilation Weaning Strategies and Correlation to Outcomes in Tracheostomized Patients in the Lausanne ICU
This retrospective study aims to study characteristics of patients tracheotomized in the Lausanne ICU, both overall and by primary reasons of intubation.
- Trial name
- NCT04987398
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- Piquilloud Imboden Lise
COVID-19 Acute Respiratory Distress Syndrome
T-Cell Mitochondrial Respiration Response to Ketone Monoester Supplement in Healthy Volunteers and COVID-19
T-Cell Mitochondrial Respiration Response to Ketone monoester (Ketoneaid) in Healthy Volunteers and COVID-19
- Trial name
- NCT05798260
- Testing
- Agilent Seahorse XF Cell Mito Stress Test
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Duke University
ICU's Patients Under Mechanical Ventilation
Effect of Drainage of Subglottic Secretions on Pneumonia Acquired Under Mechanical Ventilation
The purpose of this study is to determine whether drainage of subglottic secretions is effective to reduce the incidence of pneumonia acquired under mechanical ventilation in ICU's patients.
- Trial name
- NCT00219661
- Testing
- drainage of subglottic secretions (HiLo Evac tube)
- Where
- 4 sites in France
- Volunteers
- 440 people
- Sponsor
- Poissy-Saint Germain Hospital
Surgical Patients, Pulmonary Complication
Prophylactic Noninvasive Ventilation in vs Postoperative Standard Care in High Risk Patients According to ARISCAT Score
Postoperative pulmonary complications are one of the most common complications after surgery. Noninvasive ventilation has been proposed post-operatively to prevent postoperative pulmonary complications.
- Trial name
- ANTICIPUSC (NCT03629431)
- Testing
- Prophylactic non-invasive ventilation, postoperative standard care
- Where
- 3 sites in France
- Volunteers
- 266 people
- Sponsor
- Institut Cancerologie de l'Ouest
Respiratory Insufficiency
Outcome Evaluation of Patients After Percutaneous Tracheostomy Due to Respiratory Failure in an Intensive Care Unit
To determine the morbidity and mortality of patients who have undergone percutaneous tracheostomy due to respiratory failure in the critical care unit and after intensive care in the internal medicine department, including…
- Trial name
- NCT01693705
- Testing
- Tracheostomy
- Where
- Israel
- Volunteers
- 55 people
- Sponsor
- Hillel Yaffe Medical Center
Critically Ill, Subacute Adult Patients, Mechanically Ventilation
Effect of Inspiratory Muscle Training on Ventilated Patients in an Intensive Care Unit
The goal of this clinical trial is to learn if inspiratory muscle training facilite the liberation of mechanical ventilation. The main questions it aims to answer are: Does inspiratory muscle training facilitate weaning from…
- Trial name
- NCT06611683
- Testing
- Inspiratory muscle training, Routine care
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung University
ICU(Intensive Care Unit) Patients, Mechanical Ventilation After Surgery
Respiratory Volume Measure Using ExSpiron 1Xi
The purpose of this study was to determine the accuracy of one-time respiratory volume measured by RVM(Respiratory Volume Monitor) compared to the one-time respiratory volume measured by mechanical ventilation in post-operative…
- Trial name
- NCT02998294
- Testing
- Respiratory Volume Monitor(RVM), artificial respirator
- Where
- South Korea
- Volunteers
- 63 people
- Sponsor
- Yonsei University
Covid19, SARS-Associated Coronavirus as Cause of Disease Classified Elsewhere
Evaluation of the Efficacy of Nicotine Patches in SARS-CoV2 (COVID-19) Infection in Intensive Care Unit Patients
There is currently no known treatment for COVID19. Active smokers are infrequent among patients with COVID-19 which has led our team to hypothesize that nicotine is responsible for this protective effect via the nicotinic…
- Trial name
- NICOVID-REA (NCT04598594)
- Testing
- Patch, Nicotine
- Where
- 18 sites in France
- Volunteers
- 220 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Covid19, Acute Respiratory Failure
Noninvasive Respiratory Support in COVID-19 (CATCOVID-AIR)
COVID-19 pneumonia can cause severe acute hypoxemic respiratory failure. The usefulness of noninvasive respiratory support (NIRS), by means of nasal high-flow oxygen (NHFO), continuous positive airway pressure (CPAP), or…
- Conditions
- Covid19, Acute Respiratory Failure, Corona Virus Infection
- Trial name
- CATCOVID-AIR (NCT04668196)
- Testing
- High-flow nasal cannula treatment, Continuous positive airway pressure (CPAP) treatment, Noninvasive ventilation treatment
- Where
- 10 sites in Spain
- Volunteers
- 367 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
ARDS, TTM
TwichView-guided Atricurium Dose Adjustment Trial
The goal of this clinical trial is to learn if using a monitor that measures muscle response can lower the amount of muscle relaxant medicine needed in adults who are treated in an intensive care unit (ICU) and need a continuous…
- Conditions
- ARDS, TTM, ECMO, Neuromuscular Blockade Monitoring
- Trial name
- NCT07807046
- Testing
- EMG-based quantitative TOF-guided atracurium titration
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Fu Jen Catholic University Hospital
COVID-19
Short-term Physical Function Outcomes in Severe COVID-19 Patients Admitted to ICU for Invasive Mechanical Ventilation
Little is known about the physical function outcomes in patients with severe COVID-19 patients who are admitted to Intensive Care Unit (ICU) for invasive mechanical ventilation.
- Trial name
- NCT04400461
- Testing
- Data collection and clinical testing of subjects
- Where
- 2 sites in Spain
- Volunteers
- 71 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Mechanical Ventilation Complication, Respiratory Acidosis
VentilO Prospective Study
This is a randomized, open-label study comparing intial settings made by clinicians with settings recommandation made by the VentilO application immediately after intensive care unit admission.The study will allow direct…
- Trial name
- VentilO (NCT06826794)
- Testing
- Clinicians, VenitlO
- Where
- Canada
- Volunteers
- 76 people
- Sponsor
- Laval University
ARDS, COVID19
Evaluation of Airway Pressure Release Ventilation in COVID-19 ARDS
The 2020 pandemic of the coronavirus (SARS-CoV2) has lead to an increase in ARDS cases requiring invasive mechanical ventilation in the ICU (Intensive Care Unit).
- Trial name
- APRV-COVID19 (NCT04386369)
- Testing
- Airway pressure release ventilation
- Where
- France
- Volunteers
- 17 people
- Sponsor
- Central Hospital, Nancy, France
Acute Respiratory Distress Syndrome
Prediction of Duration of Mechanical Ventilation in ARDS
The investigators are planning to perform a secondary analysis of an academic dataset of 1,303 patients with moderate-to-severe acute respiratory distress syndrome (ARDS) included in several published cohorts (NCT00736892…
- Trial name
- PIONEER (NCT05993377)
- Testing
- Logistic regression Cross validation Area under the RIC curves Machine learning analysis. .
- Where
- 20 sites in Spain, United Kingdom
- Volunteers
- 1,303 people
- Sponsor
- Hospital Universitario de Gran Canaria Doctor Negrín
Respiratory Insufficiency, Ventilator Weaning
Correlation of Two Methods for Cough Peak Flow Measurement in Intubated Patients
Cough Peak Flow (CPF) seems to be an efficient tool to assess cough capacity for the intensive care unit (ICU) ventilated patient.
- Trial name
- COUGH-ICU (NCT03357198)
- Where
- France
- Volunteers
- 62 people
- Sponsor
- Centre Hospitalier Régional d'Orléans