Clinical trials: Intermittent Fasting, open to volunteers
Hip Osteoarthritis, Arthroplasty, Replacement, Hip
Preoperative Fasting and the Gut Microbiome Before Hip Replacement
Postoperative complications occur in 5-15% of patients undergoing elective primary total hip arthroplasty (THA), including periprosthetic joint infection (PJI), thrombosis, wound healing disorders, and metabolic dysregulation.
- Conditions
- Hip Osteoarthritis, Arthroplasty, Replacement, Hip, Postoperative Complications, Surgical Wound Infection
- Trial name
- PreFAST-Hip (NCT07651462)
- Testing
- Buchinger Fastenbox + intermittent fasting (20-day preoperative schedule)
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- Charite University, Berlin, Germany
Chronic Insomnia, Overweight/Obesity
Cognitive Behavioral Therapy for Insomnia as an Adjunct to Time-restricted Eating on Weight Loss in Adults With Overweight or Obesity and Chronic Insomnia
Obesity (being overweight due to excess body fat) is a common health condition that increases the risk of developing problems such as diabetes, high blood pressure, and heart disease.
- Trial name
- NCT07770516
- Testing
- Flexible Time-restricted eating group (FTRE), Flexible Time-restricted eating plus cognitive behavioural therapy for insomnia group (CBTI+FTRE)
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- Chinese University of Hong Kong
Nutrition, Health and Wellbeing
Early Time-Restricted Eating Combined With Exercise in Older Adults
This randomized controlled trial aims to investigate the effects of Early Time-Restricted Eating (eTRE) combined with a multicomponent exercise program on bone health, physical function, and fall risk in healthy older adults.
- Conditions
- Nutrition, Health and Wellbeing, Aging, Time Restricted Eating
- Trial name
- NCT07695961
- Testing
- Early Time-Restricted Eating (eTRE)+Exercise Intervention
- Where
- Tunisia
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Manouba
Metabolic Syndrome
Effects of Restricted-time and Psychochrononutritional Feeding in People With Metabolic Syndrome
Metabolic syndrome is a cluster of risk factors, including abdominal obesity, high blood pressure, high triglycerides, and insulin resistance, that increase the risk of developing type 2 diabetes and cardiovascular disease.
- Trial name
- PSICRONUT (NCT07389603)
- Testing
- Time restricted eating, Psychochrononutritional intervention
- Where
- Mexico
- Volunteers
- 64 people
- Sponsor
- University of Guadalajara
Breast Cancer
Impact of Intermittent Fasting on Biomarkers of Inflammation and Health-Related Quality of Life: A Feasibility Trial for Women With HR+/HER2- Early Breast Cancer
This single-arm study is designed to test the hypothesis that a six-month intermittent fasting (IF) intervention is feasible for patients to adhere to and improves health-related quality of life while subjects are on adjuvant…
- Trial name
- NCT06106477
- Testing
- Intermittent Fasting
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical College of Wisconsin
Melanoma (Skin Cancer)
Clinical Study on High-fiber Diet and Short-term Fasting in Melanoma Under Immunotherapy With Checkpoint Inhibition
The treatment of melanoma has improved significantly in recent years. A modern form of cancer treatment known as immunotherapy with checkpoint inhibitors plays a key role in this.
- Trial name
- Melafit (NCT07680452)
- Testing
- High-Fiber Diet, High-Fiber Diet and Short-Term Fasting
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Charite University, Berlin, Germany
Perioperative Care, Intermittent Fasting
Intermittent Fasting Versus Carbohydrate Drinks Before Surgery
The purpose of this study is to investigate whether time-restricted feeding, a form of intermittent fasting, before surgery improves insulin resistance around the time of surgery, compared to carbohydrate drinks and standard…
- Conditions
- Perioperative Care, Intermittent Fasting, Carbohydrate Loading, Preoperative Fasting
- Trial name
- PRINCESS (NCT05760339)
- Testing
- Time-restricted feeding, Carbohydrate loading
- Where
- Netherlands
- Volunteers
- 75 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Type 2 Diabetes Mellitus (T2DM), Time Restricted Eating
Time Restricted Eating in Patients With Microalbuminuria
This is a clinical trial to assess how time-restricted eating (TRE) may improve kidney health and filtration patients with type 2 diabetes and increased protein content in their urine.
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Time Restricted Eating, Microalbuminuria
- Trial name
- TREK (NCT06884059)
- Testing
- Time Restricted Eating
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of California, San Diego
Bipolar Disorder, Time Restricted Eating
Healthy Lifestyles in Bipolar Disorder: Bay Area Study
The goal of this clinical trial is to understand how level of adherence with time-restricted eating (TRE) predicts change in diurnal rhythms (as measured using the amplitude of diurnal peripheral clock gene expression), and how…
- Trial name
- NCT06555406
- Testing
- Time-restricted eating for 8 weeks
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of California, Berkeley
Cardiometabolic Syndrome, Type 2 Diabetes
Circadian Intervention to Improve Cardiometabolic Health
The overall goal is to examine the efficacy of a circadian intervention in people with overweight and obesity and habitual short sleep duration (HSSD).
- Conditions
- Cardiometabolic Syndrome, Type 2 Diabetes, Sleep, Time Restricted Feeding
- Trial name
- TOCS (NCT05943626)
- Testing
- Circadian Intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Utah
Gastric Emptying, Glucagon-Like Peptide-1 Receptor Agonists
Effect of Glucagon-like Peptide-1 Receptor Agonists (GLP-1 RA) on Gastric Emptying
This study aims to assess the effect of using Glucagon-like peptide-1 receptor agonists (GLP-1) receptor agonists on gastric emptying on surgical patients and whether specific guidelines need to be established for these patients.
- Conditions
- Gastric Emptying, Glucagon-Like Peptide-1 Receptor Agonists, Intermittent Fasting, Intraoperative Complication Due to Anesthesia
- Trial name
- NCT07140289
- Testing
- Ultrasound of gastric contents
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wael Saasouh, MD
Weight Loss, Weight Gain
Time Restricted Eating for WeIght LoSs MainTenance-2
The TWIST 2.0 Study is a 12-month, 2-arm RCT in adults with recent weight loss. We will examine the efficacy of TRE on weight (Aim 1a) and fat mass (Aim 1b) regain, and describe changes in subjective appetite following a…
- Conditions
- Weight Loss, Weight Gain, Weight Loss Maintenance
- Trial name
- TWIST-2 (NCT07190170)
- Testing
- TRE, Weight-Loss Maintenance Advice
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- NYU Langone Health
Adolescent Obesity
The Effect of Time-Restricted Feeding on Body Composition and Some Metabolic Parameters in Obese Adolescents
Obesity is now recognized as a serious public health problem. It is known that obesity seen in adolescence is largely carried over to adulthood.
- Trial name
- NCT06616454
- Testing
- Intervention group - Time restricted feeding
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sümeyra Başar
Central Obesity, Time Restricted Eating
Impact of Chronotype-Based Time-Restricted Eating on Visceral Fat and Metabolic Health in Physically Inactive Adults With Central Obesity
Time-restricted eating (TRE) has gained attention as a promising dietary strategy for enhancing body composition and metabolic health.
- Trial name
- NCT07062315
- Testing
- Chronotype-matched time-restricted eating, Chronotype-unmatched time-restricted eating
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Chinese University of Hong Kong
Psoriasis, PreDiabetes
Effect of Addition of Pyramidal Exercise to Intermittent Fasting on Dryness of Eye in Pre-diabetic Psoriasis Patients
insulin resistant psoriatic obese patients may complain problems of dryness of eye. Intermittent fasting may improve dryness of eye, obesity, insulin resistance, and psoriasis.
- Conditions
- Psoriasis, PreDiabetes, Obesity, Dry Eye
- Trial name
- NCT06893913
- Testing
- pyramidal training plus intermittent fasting, intermittent fasting
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Mild Cognitive Impairment, Alzheimer Disease
TREAD: Time Restricted Eating Intervention for Alzheimer's Disease
The goal of this clinical trial is to learn if restricting the time of eating to allow for prolonged fasting at night may reduce sleep disturbances, cognitive decay, and pathology in patients diagnosed with Mild Cognitive…
- Conditions
- Mild Cognitive Impairment, Alzheimer Disease, Alzheimer's Disease
- Trial name
- TREAD (NCT06548191)
- Testing
- Time-restricted eating
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Cancer
Effect of Meal Timing During Adjuvant Treatment for Cancer
The goal of this clinical trial is to test meal-timing as a novel and sustainable interventional approach during cancer treatment to improve therapeutic response, patient well-being and long-term metabolic health.
- Trial name
- NCT07524218
- Testing
- Time-restricted eating, Questionnaire Administration, Biospecimen Collection
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Fred Hutchinson Cancer Center
Type 2 Diabetes Mellitus (T2DM), Insulin Resistance
Validation of the Snouda Metabolic Score for Phenotyping and Guiding Reversal in Type 2 Diabetes
This study tests a new tool called the Snouda Metabolic Score (SMS) that helps doctors identify the specific metabolic problems driving Type 2 Diabetes in each individual patient.
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Insulin Resistance, Metabolic Syndrome
- Trial name
- SMS-VAL (NCT07606872)
- Testing
- Phenotype-Matched Dietary Protocol, Structured Progressive Exercise Protocol, Targeted Nutritional Supplementation
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- Salah Snouda
Bipolar Disorder (BD), Bipolar Disorder Depression
Time Restricted Eating (TRE) in Bipolar Disorder
This is a randomized controlled trial investigating the effects of an 8-TRE intervention compared to a wait list (control) on metabolic health and body composition in people diagnosed with BD and who are currently obese and at…
- Conditions
- Bipolar Disorder (BD), Bipolar Disorder Depression, Overweight (BMI > 30)
- Trial name
- TREBD (NCT07211217)
- Testing
- Time Restricted Eating
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital
Obesity & Overweight, Bariatric Surgery
Time-Restricted Eating After Bariatric Surgery
This study aims to compare the effects of time-restricted eating (TRE, 16/8) in adults with obesity who have and have not undergone bariatric surgery (BS).
- Conditions
- Obesity & Overweight, Bariatric Surgery, Weight Regain, Weight Regain Post Bariatric Surgery
- Trial name
- NCT07672821
- Testing
- Time-Restricted Eating (16:8)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Medipol University