Clinical trials: Internal Fixation
Fracture of Calcaneus, Pilon or Tibial Plateau
Vacuum Assisted Closure as a Treatment for Soft Tissue Injuries
This project is designed as a prospective, randomized, comparative study evaluating the use of a negative pressure vacuum device in treating soft tissue injuries and the surgical incision following open reduction and internal…
- Trial name
- VAC-ST (NCT00582998)
- Testing
- Standard Wound Dressing, Vacuum Assisted Closure Device
- Where
- United States
- Volunteers
- 249 people
- Sponsor
- University of Alabama at Birmingham
Distal Femur Fractures
Dynamic Locking Screws 5.0 vs. Standard Locking Screws in Fracture of Distal Femur Treated With Locked Plate Fixation
The purpose of this study is to evaluate the performance of Dynamic Locking Screws (DLS) used to stabilize the shaft component of distal femur fractures in comparison to standard locking screws (SLS).
- Trial name
- NCT01693367
- Testing
- DLS 5.0 (Dynamic locking screws), SLS (Standard locking screw)
- Where
- 12 sites in United States, Austria and 2 more
- Volunteers
- 5 people
- Sponsor
- AO Innovation Translation Center
Hip Fractures
Computer-Assisted Fixation of Trochanteric Femur Fractures
The purpose of this study is to assess whether the Stryker© ADAPT™ augmented-reality platform can assist surgeons in optimizing placement of the lag screw component of the Stryker© Gamma™ cephalomedullary nail.
- Trial name
- NCT04528459
- Testing
- Stryker© ADAPT™ platform, Traditional fluoroscopy
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Columbia University
Leg Injuries, Fracture
Soft Part Management for Surgical Fractures of the Lower Limb
The assessment consists in comparing corticoids injection versus placebo in surgery of lower limb fractures The aim of study is to assess (state cutaneous, efficacy, safety) corticoids injection on a prospective, randomized…
- Conditions
- Leg Injuries, Fracture, Edema
- Trial name
- ICOMI (NCT03915223)
- Testing
- leg fracture
- Where
- France
- Volunteers
- 104 people
- Sponsor
- University Hospital, Clermont-Ferrand
Supracondylar Femoral Fractures, Femoral Fractures
Robot-Assisted Closed Reduction and Internal Fixation for Distal Femoral Fractures
This study aims to evaluate the clinical efficacy and safety of an intelligent robotic system for the closed reduction of extra-articular supracondylar femoral fractures (Arbeitsgemeinschaft für Osteosynthesefragen/Orthopaedic…
- Trial name
- NCT07738406
- Testing
- Robot-assisted closed reduction, Conventional fracture reduction and internal fixation
- Where
- 2 sites in China
- Volunteers
- 80 people
- Sponsor
- Beijing Jishuitan Hospital
Body Contouring Surgery
RIBOSS-01: Prospective Controlled Clinical Trial to Evaluate the Safety and Effectiveness of Rib Osteotomy With Osteosynthesis Stabilization for Waist Narrowing
The goal of this observational study is to learn about the long-term effects of RIBOSS intervention and demonstrate non-inferiority of postoperative respiratory function (FEV1, FVC, FEV1/FVC) at 6 months in the RIBOSS group…
- Trial name
- (RIBOSS) (NCT07705295)
- Where
- Colombia
- Volunteers
- 160 people
- Sponsor
- Research Inc
Radius Fracture Distal
WALANT in Distal Radius Fracture Osteosynthesis
The purpose of this study is to assess the applicability and potential benefits of Wide Awake Local Anesthesia No Tourniquet (WALANT) or Local Anesthesia No Tourniquet ("LANT) versus locoregional anesthesia (LRA) and tourniquet…
- Trial name
- NCT05421000
- Testing
- WALANT, Locoregional anesthesia and tourniquet
- Where
- Spain
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Hospital Arnau de Vilanova
Radius; Fracture, Lower or Distal End
Role of the Pronator Quadratus in Distal Radius Fractures
The skin, the bones, and most muscles received branches from the source arteries of at least two angiosomes, thus revealing one of the important anastomotic pathways by which the circulation is reconstituted in those cases where…
- Trial name
- NCT03371030
- Testing
- Pronatus quadratus reparation
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Arthrosis
Minimal Invasive TLIF Arthrodesis Using Augmented Reality Navigation for Percutaneous Pedicle Aiming
Surgery for degenerative spondylolisthesis requires decompression of the narrow lumbar canal and fixation by osteosynthesis-arthrodesis. Conventional surgery is done through the open route.
- Trial name
- ARSN (NCT05077410)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Strasbourg, France
Le Fort; I
Accuracy of LeFort I Osteotomy Fixation Using Two Plates Versus Four Plates Patient Specific Osteosynthesis
Virtual Surgical planning (VSP) has significantly improved many aspects of oral and maxillofacial surgery. A very important aspect is surgical accuracy and precise transfer of the surgical plan to the operating theatre and…
- Trial name
- NCT05908370
- Testing
- Maxillary orthognathic surgery using 4 patient specific osteosynthesis (4-Plates)
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Femoral Fractures
Nails Versus Plates for Femur Fractures in Dar es Salaam, Tanzania
This is a prospective observational study of patients with femur fractures in Dar es Salaam, Tanzania comparing two different surgical techniques: intramedullary nailing (IMN) and open reduction internal fixation (ORIF) with a…
- Trial name
- NCT01548456
- Testing
- Intramedullary Nailing, Open Reduction Internal Fixation
- Where
- Tanzania
- Volunteers
- 332 people
- Sponsor
- University of California, San Francisco
Lumbar Disc Herniation
Lumbar Intervertebral Disc Herniation
The purpose of this study is to compare safety and outcomes of the following treatments of lumbar disc herniation: (1) discectomy with posterior dynamic stabilization with those of (2) discectomy alone or (3) discectomy with…
- Trial name
- LIDH (NCT02110186)
- Testing
- Dynamic Stabilization, Discectomy, Instrumentation and fusion
- Where
- China
- Volunteers
- 195 people
- Sponsor
- Third Military Medical University
Foot Fracture, Pain, Acute
Tramadol Simultaneously With Sciatic Nerve Block for Calcaneus Fracture Osteosynthesis
Comparison of duration of efficient analgesia after painful surgical repair od foot fractures between groups treated with sciatic nerve block alone and sciatic nerve block simultaneously with i.m. tramadol
- Trial name
- TramIsch (NCT03477851)
- Testing
- Tramadol Hydrochloride
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Medical University of Warsaw
Sternal Wound Infection, Sternal Non-union
Evaluation of Primary Plating in Sternotomy Patients for Osteosynthesis and Pain
The goal of this study is to evaluate sternal osteosynthesis, chest wall pain and return to normal activity in open heart surgery patients who had their breast bone closed either with wires or plates.
- Conditions
- Sternal Wound Infection, Sternal Non-union, Pain, Mediastinitis
- Trial name
- RESTORE (NCT00819286)
- Testing
- SternaLock Rigid Fixation Plates, wire (control)
- Where
- 6 sites in United States, Germany
- Volunteers
- 140 people
- Sponsor
- Zimmer Biomet
Acetabular Fracture
Quadrilateral Surface Plate (QSP) Focused Registry
The absence of methodologically, prospectively and retrospectively collected information on the use of the Quadrilateral Surface Plate (QSP) in the given indication requires a multicenter approach.
- Trial name
- NCT01839565
- Testing
- Quadrilateral Surface Plate
- Where
- 6 sites in Germany, Italy and 1 more
- Volunteers
- 13 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Distal Radius Fracture
Opiate Sparing Protocol Randomized Controlled Trial in Open Distal Radius Fracture Repair
A comparison of oral morphine equivalents between an opiate sparing cohort and an opiate based cohort following open reduction internal fixation of a distal radius fracture.
- Trial name
- NCT05215236
- Testing
- Opiate Sparing, Opiate Based
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Campbell Clinic
Proximal Humerus Fracture
Study on Outcomes of Proximal Humerus Fractures
Patients undergoing either operative or non-operative treatment of proximal humerus fractures will be studied with the goal of understanding which treatment modality provides optimal post-injury outcomes.
- Trial name
- NCT07060664
- Testing
- open reduction internal fixation, intramedullary nail, reverse total shoulder arthroplasty
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Massachusetts, Worcester
Supracondylar Humerus Fractures
Treatment Of Supracondylar Fractures Closed Reduction And Circular Ring External Fixation Versus Open Reduction and Internal Fixation
Patients treated with circular external fixation will have better outcomes (as measured by range of motion (ROM), alignment, outcome surveys) than those treated with open reduction and internal fixation (ORIF).
- Trial name
- NCT02196311
- Where
- United States
- Sponsor
- Baylor College of Medicine
Patella Fracture
Management Of Patellar Fractures By Craniofacial Mesh Plate Osteosynthesis Augmented by Screws
Patellar fractures are challenging orthopedic injuries. Fractures that result in disruption of the extensor mechanism led to significant functional deficits.
- Trial name
- NCT06205914
- Testing
- fixation of patella fractures by craniofacial mesh plate osteosynthesis augmented by screws
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Pain, Postoperative
Celecoxib in Postoperative Analgesia for Radius Fracture Surgery
Patients scheduled for elective osteosynthesis of the distal radius will be randomized to receive celecoxib 100 mg orally (PO) at 6 in the morning before surgery and every 12 hours for 2 days thereafter, or a placebo pill in the…
- Trial name
- NCT05288374
- Testing
- Celecoxib 100 mg
- Where
- 2 sites in Czechia
- Volunteers
- 42 people
- Sponsor
- Charles University, Czech Republic