Clinical trials: Internal Hernia
Inguinal Hernia
Open and Laparoscopic Hernia Repair. A Comparative Study
A retrospective comparative study in a pediatric surgery center to compare the outcomes of 2 approaches of hernia repair in the pediatric population.
- Trial name
- NCT05011786
- Testing
- hernia repair/ligation of the hernial sac
- Where
- Jordan
- Volunteers
- 155 people
- Sponsor
- Ibrahim Khrais
Ventral Hernia
Regional Differences In Indication for Ventral Hernia Repair
The aim of the present study is to investigate whether there are differences in indication for ventral hernia repair and surgical approach among hernia surgeons from different geographical regions of Denmark.
- Trial name
- NCT02263625
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Hernia, Abdominal, Recurrence
Nationwide Long-term Outcome Surveillance of Physiomesh® vs. Other Meshes in Laparoscopic Incisional Hernia Repair
The primary aim of the present study was to show how a national clinical register combined with other nationwide administrative registers may serve as a tool for pre- and post-marketing evaluation of new mesh and mesh fixation…
- Conditions
- Hernia, Abdominal, Recurrence, Postoperative Complications
- Trial name
- NCT03846661
- Testing
- Physiomesh
- Where
- Denmark
- Volunteers
- 3,338 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Congenital Diaphragmatic Hernia
CDH - Optimisation of Neonatal Ventilation
To determine the appropriate volume (size) of ventilator breath during volume-targetted ventilation for infants born with congenital diaphragmatic hernia.
- Trial name
- CDH-ONV (NCT02849054)
- Testing
- Measurement of PTPdi, TTV at 4ml/kg, TTV at 5ml/kg
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- King's College London
HERNIA, VENTRAL
ProLOVE - Prospective Randomized Study of Midline Incisional Hernia Treatment
This purpose of this study is to compare the recovery after an operation of an incisional hernia within the limits of the rectus muscles of the abdominal wall.
- Trial name
- ProLOVE (NCT00472537)
- Testing
- Retromuscular Mesh repair of midline incisional hernia, Laparoscopic repair of midline incisional hernia
- Where
- 7 sites in Sweden
- Volunteers
- 157 people
- Sponsor
- Skane University Hospital
Inguinal Hernia Unilateral, Inguinal Hernia Bilateral
Reversing InGuinal Hernia Trial: The Evaluation of Sex Hormones to Reverse Inguinal Hernias in Males
This is a prospective, single-center, two-arm Phase 1 safety and feasibility trial evaluating anti-estrogen therapy in men age 50 years and older with symptomatic unilateral inguinal hernias.
- Conditions
- Inguinal Hernia Unilateral, Inguinal Hernia Bilateral, Inguinal Hernia Without Obstruction or Gangrene, Inguinal Hernia, Without Mention of Obstruction or Gangrene
- Trial name
- RIGHT (NCT07604272)
- Testing
- Fulvestrant, Anastrozole (ARIMIDEX™)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Northwestern University
Congenital Diaphragmatic Hernia
3D Animation and Models to Aid Management of Fetal CDH
We wish to use the images a mother would have done as part of her normal medical care and make both 3D animations and 3D models of the baby and it's CDH.
- Trial name
- NCT03750266
- Testing
- No intervention data collected through routine scans
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Gastroschisis, Intestinal Ischemia
Regional Blood Saturation Levels in Gastroschisis
Gastroschisis is one of the most common neonatal surgical conditions, and is increasing in incidence. Postnatal bowel ischemia leading to necrosis, bowel loss and short-bowel syndrome, occurs in a few instances, with significant…
- Trial name
- NCT03533439
- Testing
- Near infrared spectroscopy
- Volunteers
- 19 people
- Sponsor
- NHS Lothian
Hernia, Ventral, Incisional Hernia
A Prospective Trial of a Bio-absorbable Mesh in Challenging Laparoscopic Ventral or Incisional Hernia Repair
The objective of this study is to collect additional data on safety, performance and effectiveness of Phasix™ ST in subjects receiving laparoscopic ventral or incisional hernia repair at high risk for surgical site occurrence…
- Trial name
- ATLAS (NCT02712398)
- Testing
- Phasix™ ST
- Where
- 16 sites in United States
- Volunteers
- 120 people
- Sponsor
- C. R. Bard
The Prevalence of Surgery for Small Bowel Obstruction After LGBP Procedure.
Internal Hernia After Laparoscopic Gastric Bypass
To see if closing the mesenteric defects created at a Laparoscopic Gastric Bypass is better than leaving them open.
- Trial name
- NCT01137201
- Testing
- Suturing of mesenteric defects
- Where
- Sweden
- Volunteers
- 2,507 people
- Sponsor
- Region Örebro County
Inguinal Hernia
Inguinal Hernia Study Using Biodesign IHM
Aim is to evaluate outcomes of inguinal hernia repair incorporating the standard Lichtenstein (open) repair using Biodesign IHM in a double blind (physician evaluator and patient will be blinded), randomized, prospective…
- Trial name
- NCT00393887
- Testing
- Biodesign IHM, Polypropylene mesh
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Cook Group Incorporated
Congenital Diaphragmatic Hernia
Pilot Trial of Fetoscopic Endoluminal Tracheal Occlusion (FETO) in Severe Left Congenital Diaphragmatic Hernia (CDH)
Despite advances in prenatal diagnosis and postnatal therapies, including ECMO (Extracorporeal Membrane Oxygenation), inhaled nitric oxide therapy, and ventilator strategies that minimize ventilator-induced lung injury, morbidity…
- Trial name
- NCT04583644
- Testing
- Fetoscopic Endoluminal Tracheal Occlusion Surgery
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Hanmin Lee
Ventral Hernia, Umbilical Hernia
Case-control Study of Mesh-infection After a Size Tailored Hernia Repair With C-Qur V-Patch
Ventral hernias, such as umbilical, epigastric and trocar-site hernias, are best repaired with abdominal wall reinforcement by mesh implantation.
- Conditions
- Ventral Hernia, Umbilical Hernia, Epigastric Hernia, Trocar-site Hernia
- Trial name
- Re-SITUP (NCT01761708)
- Testing
- primary ventral hernia repair with mesh
- Where
- Belgium
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Hernia, Inguinal
Effects of Using Divided Mesh and Using a Non Divided Mesh on Testicular Blood Flow and Volume in Laparoscopic Hernia Repair
Laparoscopic inguinal hernia repair techniques has been compared with the open techniques in several studies. However, no one studied about the different uses of the same type of mesh on the same surgical technique, and effects…
- Trial name
- NCT03421925
- Testing
- Laparoscopic totally extraperitoneal procedure for inguinal hernia
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Okan University
Inguinal Hernia Repair, Postoperative Pain
Spinal Anesthesia Versus Erector Spina Plane Block
The primary aim of our study was to use spinal anesthesia for unilateral inguinal hernia surgery and lumbar erector spina block supported by local infiltration anesthesia in terms of operation time, intraoperative hemodynamic…
- Conditions
- Inguinal Hernia Repair, Postoperative Pain, Peripheral Nerve Blocks
- Trial name
- NCT05073055
- Testing
- İnguinal Hernia Repair
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Nigde Omer Halisdemir University
Congenital Diaphragmatic Hernia
Type of Material in Repair of Congenital Diaphragmatic Hernia
The objective of this study is to evaluate the use of 2 different types of biosynthetic material for the repair of congenital diaphragmatic hernia.
- Trial name
- NCT00257946
- Testing
- Repair of CDH w/SIS Gold, Repair of CDH w/Alloderm
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Children's Mercy Hospital Kansas City
Umbilical Hernia Repair
Topical Tranexamic Acid Spray Versus No Spray on Postoperative Outcomes Following Mesh Repair of Umbilical Hernia
Umbilical hernia is a type of ventral hernia that occurs commonly in adulthood, and mesh reinforcement is well established since there is a reduced recurrence rate when compared to suture repair.
- Trial name
- NCT07845370
- Testing
- Topical Tranexamic Acid Spray, No Topical Tranexamic acid
- Where
- Pakistan
- Volunteers
- 252 people
- Sponsor
- Dr Mudassar Saeed Pansota
Hernia, Ventral, Ventral Incisional Hernia
Use of Mosquito Net Mesh for Ventral Hernia Repair
It´s a pilot study, randomized, realized in the Central Hospital "Dr. Ignacio Morones Prieto", SLP, Mexico. Hypothesis: The polyethylene mesh is secure in open ventral repair.
- Trial name
- NCT03324854
- Testing
- Rives technique, Drainage, Prophylactic
- Volunteers
- 20 people
- Sponsor
- Hospital Central "Dr. Ignacio Morones Prieto"
Analgesia
Pediatric Postoperative Analgesia Herniorrhaphy Study
This is a Phase 2 study in pediatric subjects undergoing inguinal herniorrhaphy.
- Trial name
- NCT03922048
- Testing
- HTX-011, Bupivacaine HCl, Luer Lock Applicator
- Sponsor
- Heron Therapeutics
Congenital Diaphragmatic Hernia
Gene Mutations and Rescue in Human Congenital Diaphragmatic Hernia
Congenital diaphragmatic hernia (CDH) occurs when the diaphragm, the muscle that separates the chest cavity from the abdominal cavity, does not form properly.
- Trial name
- NCT01098929
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital