Clinical trials: Internal Limiting Membrane Peeling, open to volunteers
Myopic Traction Maculopathy
Predictors of Vitrectomy Outcomes in Myopic Foveoschisis
This prospective pilot study evaluates factors that predict outcomes after vitrectomy for myopic foveoschisis (MFS), a sight-threatening complication of high myopia that can lead to progressive visual loss, foveal detachment…
- Trial name
- NCT07774637
- Testing
- pars plana vitrectomy
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- Singapore National Eye Centre
Idiopathic Epiretinal Membranes
Clinical Evaluation of With or Without Internal Limiting Membrane Peeling for Idiopathic Epiretinal Membrane Surgery: A Randomized Controlled Trial
Idiopathic epiretinal membrane (ERM) is an age-related degenerative retinal condition. One of the primary treatment approaches is vitrectomy combined with epiretinal membrane peeling.
- Trial name
- NCT07142785
- Testing
- Epiretinal membrane peeling, Epiretinal membrane peeling combined with internal limiting membrane peeling
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Macular Holes
PEELED INTERNAL LIMITING MEMBRANE REPOSITION
Macular hiatus (MH) refers to a tissue defect in the photoreceptor cell layer of the inner boundary membrane of the optic disc in the macular region.
- Trial name
- NCT06359548
- Testing
- Peeled ILM Reposition, ILM Peeling
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Retinal Detachment, Proliferative Vitreoretinopathy
Internal Limiting Membrane Peeling in Retinal Detachment Surgery
Despite advances in surgical techniques over the recent decades, proliferative vitreoretinopathy (PVR) remains the main obstacle to successful rhegmatogenous retinal detachment (RRD) repair, accounting for nearly 75% of all…
- Trial name
- IMPURITY (NCT05538156)
- Testing
- Control group, Intervention group
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Macular Hole Surgery, ILM Peeling
Comparison Between Outcomes of Closure of Idiopathic Macular Hole Using Autologus Tenon Capsule Graft and Internal Limiting Membrane Flap Techniques (Pilot Study)
The aim of this study is to compare the functional visual outcomes, anatomical closure rate and macular perfusion changes assessed by OCT and OCTA after surgical repair of macular hole using Tenon capsule graft versus ILM flap.
- Conditions
- Macular Hole Surgery, ILM Peeling, Tenon Capsule, ILM Flap
- Trial name
- NCT07633457
- Testing
- vitrectomy under topical anesthesia [Proparacaine HCL (Alcaine®)]
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Ain Shams University
Macular Holes
Full-Thickness Macular Hole Surgery: A Comparison of Ten Techniques
This study compares ten modern vitreoretinal surgical techniques for full-thickness macular hole repair. Participants will be randomly assigned to one of the surgical approaches during pars plana vitrectomy, using stratified…
- Trial name
- FTMH-10 (NCT07606404)
- Testing
- Pars Plana Vitrectomy (PPV)-Based Macular Hole Surgery, Autologous Platelet-Rich Plasma (PRP), Human Amniotic Membrane (hAM) Graft
- Where
- Kazakhstan
- Volunteers
- 120 people
- Sponsor
- Kazakh Eye Research Institute
Retinal Detachment Rhegmatogenous, ILM Peeling
1ry Versus 2ry ILM Peeling in RD
Patients with uncomplicated rhegmatogenous retinal detachment will be recruited. All eyes will underwent 23G PPV with silicon oil tamponade. The eyes will be classified into two groups according to the timing of ILM peeling.
- Trial name
- NCT07346560
- Testing
- Primary ILM peeling, Secondary ILM peeling
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Macular Hole, Macular Hole Surgery
No Endotamponade for Macular Hole Repair: the NEMAR Study
Full-thickness macular hole (MH) is a common sight threatening macular condition with a prevalence of 3.3 per 1000 individuals. Prompt surgical repair of MH is imperative in preventing irreversible vision loss from MH as the…
- Trial name
- NEMAR (NCT06908824)
- Testing
- Conventional surgery, ILM flap with no gas tamponade
- Where
- 3 sites in Hong Kong, Poland and 1 more
- Volunteers
- 180 people
- Sponsor
- Chinese University of Hong Kong