Clinical trials: Internalizing Disorder
Anxiety, Depressive Symptoms
A Single-Session Intervention for Adolescents and Young Adults With Internalizing Problems
With the increasing number of adolescents and young adults (AYA) experiencing depression and anxiety, paired with the lack of time, access, and funding towards social services, AYA need a mental health intervention that is…
- Trial name
- NCT05826392
- Testing
- Adolescent/Young Adult Self-Administered Web-Based Single-Session Intervention
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Child Behavior Problem
Effectiveness of Group CBT in Children With Mixed Psychiatric Disorders
This study aims to examine the immediate and longer-term effectiveness of a group cognitive behavioral therapy intervention (GCBT) in reducing internalizing and externalizing symptoms in children treated for mixed psychiatric…
- Trial name
- NCT05519943
- Testing
- The Friends program, TAU condition
- Volunteers
- 103 people
- Sponsor
- Helsinki University Central Hospital
Depressive Disorder, Depressive Symptoms
Super Skills for Life Effectiveness in the Online Modality
The study aims to evaluate the effectiveness of the transdiagnostic program Super Skills for Life (SSL). This protocol targets children aged 8 to 12 with emotional problems (anxiety, depression, low self-esteem, and lack of…
- Conditions
- Depressive Disorder, Depressive Symptoms, Anxiety Disorders, Anxiety Disorders and Symptoms
- Trial name
- NCT05589090
- Testing
- Super Skills for Life program
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Miguel Hernandez de Elche
Social Anxiety Disorder (SAD), Oppositional Defiant Disorder
ACTsocially: The (Dis)Similarities of ACT for Changing Internalizing and Externalizing Symptomatology in Adolescence
Social functioning, fundamental to adolescent's development and mental health, may be impaired by polarizing problematic social functioning, namely externalizing symptoms manifested by Oppositional Defiant Disorder and…
- Trial name
- ACTsocially (NCT07456631)
- Testing
- ACTsocially
- Where
- Portugal
- Volunteers
- 54 people
- Sponsor
- University of Coimbra
General Psychopathology, Fatigue
An Energetic View on Creativity, Psychopathology and Intelligence: The Brain2Business Study
The interventional part of the study aims to assess the acute effect of the Brain2Business (B2B) tool on creative thinking (primary objective) in adults with psychological disorders.
- Conditions
- General Psychopathology, Fatigue, Depressive Disorder, Major
- Trial name
- B2B (NCT05544877)
- Testing
- Integrated 5-day Gratitude Exercise and Behavioral Activation Program
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Psychiatrische Dienste Thurgau
Anxiety, Depression
Evaluating Knowledge Insight Tools (KIT) for Reducing Anxiety and Low Mood in UK Secondary School Students
Background and Study Aims: Secondary school students are reporting unprecedented levels of anxiety and mood difficulties. To ensure that the needs of all young people are met, there is a need to evaluate more accessible forms of…
- Conditions
- Anxiety, Depression, Internalizing Problems, Low Mood
- Trial name
- NCT06188962
- Testing
- CBT-informed school-based counselling
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- University College, London
Common Mental Health Problems, Anxiety
Trial of an Online Group Psychotherapy Intervention for Common Mental Health Disorders
The goal of this clinical trial is to understand how to deliver online group therapy for adults with common mental health problems in a personalised way.
- Conditions
- Common Mental Health Problems, Anxiety, Depression Disorders
- Trial name
- UpLift-X (NCT06722781)
- Testing
- Unified Protocol
- Where
- 2 sites in United Kingdom
- Volunteers
- 660 people
- Sponsor
- Rotherham Doncaster and South Humber NHS Foundation Trust
Chronic Stress, Anxiety
Preventing Internalizing in Preadolescents Exposed to Chronic Stress
Racial and socioeconomic disparities in physical and mental health problems are large, persistent, and severe; begin during childhood; and stem from in part damage to physiologic stress response systems caused by chronic stress.
- Conditions
- Chronic Stress, Anxiety, Depression
- Trial name
- NCT02764138
- Testing
- Building a Strong Identity and Coping Skills
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Penn State University
Antisocial, Aggressive
Effect of Omega-3 Supplementation on Child Behavior Problems
The primary purpose of this study was to assess the effectiveness of omega-3 supplementation on behavior problems in children.
- Conditions
- Antisocial, Aggressive, Externalizing Behavior Problems, Internalizing Behavior Problems
- Trial name
- NCT02016079
- Testing
- omega-3
- Where
- Mauritius
- Volunteers
- 200 people
- Sponsor
- Joint Child Health Project, Mauritius
Psychopathology, Child Mental Health
Experimental Evidence of the Impact of Parental Income on Child Mental Health and Neuroimmune Function
Growing up in a lower-income family robustly predicts worse mental health in adolescence and early adulthood. How does variability in family income "get under the skin" of the developing child and via what mechanisms does it…
- Conditions
- Psychopathology, Child Mental Health, Anxiety Disorders, Mental Disorders
- Trial name
- NCT07641244
- Testing
- Psychological fMRI task
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Northwestern University
Anxiety, Depression
Brief Cognitive Behavioral Therapy (CBT) for Pediatric Anxiety and Depression in Primary Care
The purpose of this study is to determine whether a brief (12 week) psychological treatment program, based in primary care, can help youths struggling with anxiety and/or depression.
- Trial name
- BCBT-PC (NCT01147614)
- Testing
- Brief Cognitive Behavioral Therapy (BCBT), Specialty mental health care referral (SMHC)
- Where
- 2 sites in United States
- Volunteers
- 185 people
- Sponsor
- San Diego State University
Child Neglect, Internalizing Disorder
Child and Parent-directed Individualized Psychotherapy (CPIP)
With CPIP the investigators opt for a manualized modular psychotherapy designed especially to meet the needs of children with internalizing disorders that suffered or still suffer from emotional or physiological neglect.
- Trial name
- AMIS-II-RCT (NCT05128669)
- Testing
- CPIP, ECS
- Where
- 2 sites in Germany
- Volunteers
- 200 people
- Sponsor
- University of Leipzig
Internalizing Psychopathologies (IPs) Depression and Anxiety
Negative Valence Brain Targets and Predictors of Anxiety and Depression Treatment
Internalizing psychopathologies (IPs) involving depression and anxiety are among the most prevalent, costly and disabling illnesses.
- Trial name
- NCT01903447
- Testing
- SSRI, CBT
- Where
- United States
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Anxiety Disorders, Depressive Disorder
Brief Transdiagnostic Group CBT for Adolescents With Internalizing Problems: A Randomized Waitlist Controlled Trial
The investigators will evaluate a brief group-based cognitive-behavioral treatment program for adolescents aged 13-17 years with internalizing problems.
- Conditions
- Anxiety Disorders, Depressive Disorder, Anxiety, Depression
- Trial name
- NCT04716777
- Testing
- Brief Transdiagnostic group-based Cognitive-Behavioral Treatment
- Where
- Iceland
- Volunteers
- 50 people
- Sponsor
- University of Iceland
Anxiety Disorders, Social Anxiety Disorder
Transdiagnostic Internet-delivered REBT Intervention for Adolescents' Internalizing Problems
To investigate the efficacy and mechanisms of change of an Internet-delivered transdiagnostic REBT intervention for adolescents with internalizing problems.
- Conditions
- Anxiety Disorders, Social Anxiety Disorder, Generalized Anxiety Disorder, Panic Disorder
- Trial name
- REBTonAd (NCT04179526)
- Testing
- Transdiagnostic Internet-delivered REBT
- Where
- Romania
- Volunteers
- 106 people
- Sponsor
- Babes-Bolyai University
Mental Health, Parenting / Maternal Behavior
Healing Hearts: A Mindfulness App for Parents Navigating Divorce or Separation
This study examines online programs for parents navigating divorce or separation. Researchers will study whether a self-guided mindfulness app called Healing Hearts, followed by a self-guided online parenting program called the…
- Conditions
- Mental Health, Parenting / Maternal Behavior, Parenting Anxiety, Parenting Behavior
- Trial name
- NCT07871916
- Testing
- Healing Hearts, electronic New Beginnings Program, Curated internet resources
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Emotional Problem, Anxiety
A Transdiagnostic Internet Intervention for Parents of Children With Anxiety and Depressive Symptoms
The purpose of this study is to evaluate the efficacy of a transdiagnostic, parent-led, Internet-delivered intervention in reducing child and adolescent internalizing problems.
- Conditions
- Emotional Problem, Anxiety, Depression, Psychological Distress
- Trial name
- ParentKIT (NCT05341297)
- Testing
- ParentKIT
- Where
- Romania
- Volunteers
- 111 people
- Sponsor
- Babes-Bolyai University
Anxiety Disorders, Depressive Disorder
Transdiagnostic Internet-delivered Intervention for Adolescents With Anxiety and Depression
The goal of this clinical trial is to test the efficacy of a transdiagnostic Internet-delivered interventions for Romanian adolescents with anxiety and/ or depression.
- Conditions
- Anxiety Disorders, Depressive Disorder, Social Anxiety Disorder, Major Depressive Disorder
- Trial name
- NEURO4C (NCT06724666)
- Testing
- Transdiagnostic Internet-delivered intervention
- Where
- 2 sites in Romania
- Volunteers
- 198 people
- Sponsor
- Babes-Bolyai University
Well-Being (Psychological Flourishing), Internalizing Mental Health Symptoms
Micropractices for Unhoused LGBTQ Youth
In the present study, the investigators will conduct a pilot randomized controlled trial to evaluate the feasibility, acceptability, and preliminary efficacy of brief, co-designed mindfulness and identity-affirming micropractices…
- Conditions
- Well-Being (Psychological Flourishing), Internalizing Mental Health Symptoms, Substance Abuse
- Trial name
- NCT07566273
- Testing
- Mindfulness and Identity-Based Micropractice, Control Condition Micropractice
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cornell University
Alcohol Use Disorder (AUD)
Online Interventions to Prevent Alcohol Use Disorders
Background: Internet-based interventions can improve access to non-treatment-seeking populations, preventing the onset or progression of alcohol use disorder (AUD).
- Trial name
- NCT07373405
- Testing
- Internet-Based Brief Alcohol Intervention, Unguided Internet-Based Cognitive Behavioral Therapy, Guided Internet-Based Cognitive Behavioral Therapy
- Volunteers
- 3,519 people
- Sponsor
- University of Southern Denmark