Clinical trials: Interoception
Major Depressive Episode, Major Depressive Disorder
Depression-Reduction by Accelerated Personalized NeuroModulation and Its Effects on Sleep
Advances in repetitive transcranial magnetic stimulation (rTMS) protocols with intermittent theta-burst stimulation (iTBS) have significantly decreased the duration for one single session and thereby enabled accelerated treatment…
- Conditions
- Major Depressive Episode, Major Depressive Disorder, Borderline Personality Disorder
- Trial name
- DREAMS (NCT04832750)
- Where
- Germany
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Oldenburg
Functional Neurological Disorder, Functional Movement Disorder
Additive Effects of Interoceptive Training to Physiotherapy in Functional Movement Disorders (interoPTfmd)
Functional movement disorder (FMD) is a common source of neurological disability that imposes a significant financial burden on healthcare systems.
- Trial name
- interoPTfmd (NCT06792760)
- Testing
- Physiotherapy, Specific Breathing Techniques
- Where
- Czechia
- Volunteers
- 80 people
- Sponsor
- Charles University, Czech Republic
Impaired Awareness of Hypoglycemia, Interoceptive Awareness
Adapted Mindfulness Training for Diabetic Patients With Impaired Hypoglycemia Awareness
The purpose of this randomized controlled trial is to evaluate the effectiveness of an 8-week interoception-integrated adapted mindfulness training program for patients with type 1 or type 2 diabetes who experience impaired…
- Conditions
- Impaired Awareness of Hypoglycemia, Interoceptive Awareness, Mindfulness-based Intervention
- Trial name
- NCT07586527
- Testing
- Adapted Mindfulness Training, Routine Intervention
- Volunteers
- 100 people
- Sponsor
- Yangzhou University
Healthy
BreatheWell: Train Your Breathing, Relax Your Body, Open Your Mind
The goal of this study is to determine whether tasks related to breathing training (daily inspiratory muscle training (IMT) and increased access to health data/awareness) performed for 12 weeks leads to positive changes in mental…
- Trial name
- NCT06920407
- Testing
- Breathing training device (Inspiratory Muscle Training), Oura Ring
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Chronic Pain
Interoception-Based Yoga for Chronic Pain
The purpose of this research is to examine the feasibility and acceptability of an interoception-based yoga program for chronic pain.
- Trial name
- NCT06268197
- Testing
- Yoga Intervention
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Illinois at Urbana-Champaign
Functional Neurological Disorder
The Role of Oxytocin and Interoception in Functional Neurological Disorder
The main goal of this project is to better understand the role of oxytocin and Interoception in FND. More specifically oxytocin's association with precision weighing, prediction errors and priors in the interoceptive domains will…
- Trial name
- NCT06084325
- Testing
- Respiration resistance sensitivity task (RRST), Heartbeat Tracking (HBT), Heartbeat evoked potential (HEP)
- Where
- 2 sites in Switzerland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Fribourg
Post Traumatic Stress Disorder, Insomnia
Evaluation of Yoga for Sleep Disturbances in Post Traumatic Stress Disorder (PTSD)
The primary objective of this preliminary study is to estimate sleep outcome effect sizes and determine feasibility for a novel yoga treatment of insomnia in participants with post traumatic stress disorder (PTSD).
- Trial name
- NCT01556074
- Testing
- Yoga treatment
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Brigham and Women's Hospital
Healthy
Serotonin, Anxiety and Visceral Sensation
The goal of this crossover study was to learn about the potential regulatory role of serotonin in interoceptive processing and its relationship to levels of state anxiety.
- Trial name
- NCT06212284
- Testing
- Citalopram 20mg
- Where
- United Kingdom
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Sussex
Depression - Major Depressive Disorder
Modulating Spinal Interoceptive Pathways to Evaluate Their Role and Therapeutic Potential in MDD Symptomatic Domains
Spinal interoceptive pathways (SIPs) convey bodily signals to an interoceptive system in the brain and their dysregulation is linked to major depressive disorder (MDD).
- Trial name
- MOSPID (NCT06795451)
- Testing
- transcutaneous spinal direct current stimulation
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of Cincinnati
Stress, Anxiety
Effects of HRV Biofeedback, Interoceptive Training, and Mindfulness on Stress in University Students and Staff
The goal of this clinical trial is to learn if Heart Rate Variability Biofeedback (HRV-BF), Mindfulness programs, and Interoception training can reduce stress, improve well-being, and induce brain changes in university students…
- Trial name
- BIMStress (NCT06695715)
- Testing
- Mindfulness Training Program, HRV Biofeedback, Interoception Training
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Seville
Healthy Volunteers
Vestibular Perception Gates Autonomic Responses to Sinusoidal Galvanic Vestibular Stimulation
Brief Summary This randomized, double-blind, sham-controlled clinical trial is designed to investigate whether repeated sinusoidal galvanic vestibular stimulation (GVS) influences cardiac autonomic regulation in healthy adults…
- Trial name
- GVS-HRV (NCT07715227)
- Testing
- Galvanic Vestibular Stimulation (GVS) using BrainPatch device
- Where
- 2 sites in Kazakhstan
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Al-Farabi Kazakh National University
Obesity, Childhood, Eating Behavior
Interoception and Eating Behaviors in Children
The purpose of this study is to examine how individual differences in interoception (the ability to sense, interpret, and act on bodily feelings like hunger, fullness, thirst, hot, cold, etc.) relate to eating behaviors in…
- Trial name
- I-EAT (NCT06504654)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Penn State University
Anorexia Nervosa
Gastrointestinal Interoception in Anorexia Nervosa
Anorexia nervosa (AN) has among the highest mortality rate of any psychiatric illness, yet we have a poor understanding of the biological causes of this disorder.
- Trial name
- NCT05111977
- Testing
- Vibrant capsule
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Obesity
Interoception and Illness Perception Before and After Bariatric Surgery: Impact on Disordered Eating (Interoceptiv-BAR)
Obesity is associated with alterations in the perception and interpretation of internal bodily signals (interoception), which may influence eating behaviors, emotional regulation, and long-term weight outcomes.
- Trial name
- NCT07594275
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Healthy
Interoception and Body Scan
Body scan meditation has been assumed to be an interoceptive intervention, and the evidence for its effects on interoceptive processes is unclear.
- Trial name
- NCT06237530
- Testing
- Visceral body scan (VBS), Somatosensory body scan (SBS), External control meditation (ECM)
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Safety, Psychological, Acceptability of Health Care
Body-oriented Psychotherapy for Individuals With a History of Child Maltreatment and Trauma-related Symptoms
This Pilot Randomized Controlled Trial (RCT) overall aim is to establish the safety, feasibility, acceptability and preliminary effects of a body-oriented psychotherapy, Somatic Experiencing (SE), on social functioning and mental…
- Conditions
- Safety, Psychological, Acceptability of Health Care, Psychological Safety, Maltreatment, Child
- Trial name
- NCT06549777
- Testing
- SE-group, Control
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Monique Pfaltz
Stress, Pain
State-dependent Interoception, Value-based Decision-making, and Introspection
Background: Negative emotional states can affect a person s behavior as they make decisions. For example, hunger may make people more impatient; they may then make riskier choices.
- Conditions
- Stress, Pain, Emotions, Craving
- Trial name
- NCT05666726
- Testing
- Pain, Stress, Craving
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Stroke, Ischemic, Transient Ischemic Attack
Pathophysiology and Risk of Atrial Fibrillation Detected After Ischemic Stroke
This prospective non-interventional cohort study investigates the pathophysiology of Atrial Fibrillation Detected After Stroke or transient ischemic attack (AFDAS) by comparing the autonomic function and inflammation between…
- Conditions
- Stroke, Ischemic, Transient Ischemic Attack, Atrial Fibrillation
- Trial name
- PARADISE (NCT03275155)
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Musculoskeletal Pain, Chronic Pain
Sense to Act: An Interoceptive Sensibility Intervention for Musculoskeletal Pain
The ability to be connected and act according to bodily information is fundamental in chronic pain adjustment. This study aims to test the feasibility of an intervention designed to improve interoceptive sensibility, i.e., the…
- Trial name
- NCT06285864
- Testing
- Interoception-based intervention
- Where
- 2 sites in Portugal
- Volunteers
- 71 people
- Sponsor
- Iscte-University Institute of Lisbon
Healthy Lifestyle
Improving Wellbeing Through the Brain-Gut-Microbiota Axis
Well-being is a state defined as the optimal psychological functioning and the experience associated with it, integrating physical and subjective factors.
- Trial name
- IBMA (NCT04823533)
- Where
- Chile
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile