Clinical trials: Interoception, active
Functional Dyspepsia, Anorexia Nervosa
Identifying Multidimensional Signatures of Gastric Interoception in Functional Dyspepsia
This study is being conducted to investigate gut-brain communication in individuals with functional dyspepsia and anorexia nervosa.
- Trial name
- IMAGINE (NCT07772167)
- Testing
- Functional magnetic resonance imaging (fMRI)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Cardiovascular Diseases, Coronary Artery Disease
Depressive Symptoms After Cardiac Surgery
The primary goal of this project is to develop a predictive model for clinically significant depressive symptoms (CSDS) in patients undergoing coronary artery bypass graft (CABG) surgery, using pre- and perioperative data.
- Conditions
- Cardiovascular Diseases, Coronary Artery Disease, Heart Diseases, Depression
- Trial name
- PCD (NCT06706323)
- Where
- 2 sites in Switzerland
- Volunteers
- 300 people
- Sponsor
- Roland von Känel
Interoception, Pulmonary Hypertension
Interoceptive Intervention for Pulmonary Hypertension
Background Pulmonary hypertension is a rare and incurable condition characterised by fatigue and breathlessness. The effects of pulmonary hypertension has a significant impact on an individual's emotional wellbeing and there are…
- Trial name
- NCT06443580
- Testing
- interoceptive group based intervention
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- Golden Jubilee National Hospital
Healthy
Individual Differences in Cognitive Control Predict Real-time fMRI Neurofeedback Performance
The goal of this study is to investgate whether individual differences of cognitive control capacity could predict neurofeedback performance and the behavioral effects resulting from successful anterior insula regulation via…
- Trial name
- NCT07211269
- Testing
- Real-time fMRI neurofeedback training
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Functional Neurological Disorder, Functional Movement Disorder
Additive Effects of Interoceptive Training to Physiotherapy in Functional Movement Disorders (interoPTfmd)
Functional movement disorder (FMD) is a common source of neurological disability that imposes a significant financial burden on healthcare systems.
- Trial name
- interoPTfmd (NCT06792760)
- Testing
- Physiotherapy, Specific Breathing Techniques
- Where
- Czechia
- Volunteers
- 80 people
- Sponsor
- Charles University, Czech Republic
Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Interoceptive Awareness
Interoception and Symptom Perception in Acute COPD Exacerbation
Interoception refers to the process of perceiving and interpreting internal physiological signals and plays a central role in symptom perception.
- Trial name
- NCT07719231
- Testing
- No Intervention: Observational Cohort
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Saglik Bilimleri Universitesi
Depression - Major Depressive Disorder
Modulating Spinal Interoceptive Pathways to Evaluate Their Role and Therapeutic Potential in MDD Symptomatic Domains
Spinal interoceptive pathways (SIPs) convey bodily signals to an interoceptive system in the brain and their dysregulation is linked to major depressive disorder (MDD).
- Trial name
- MOSPID (NCT06795451)
- Testing
- transcutaneous spinal direct current stimulation
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of Cincinnati
University Students
Pain Prediction Via Machine Learning: Electrical Thresholds and Interoception
The goal of this observational study is to predict (retrospective and prospective) musculoskeletal pain in university students using machine learning models based on electrical threshold measurements and interoceptive awareness.
- Trial name
- NCT07839520
- Testing
- No Intervention: Observational Cohort
- Where
- Turkey (Türkiye)
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Amasya University
Stroke
Interoception in Stroke
This study aims to examine the associations of interoceptive awareness and interoceptive accuracy with plantar superficial sensory threshold, knee joint proprioception, pain intensity, and dynamic balance performance in…
- Trial name
- NCT07669246
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istinye University
Constipation, Irritable Bowel Disease
Relationship Between Interoception and Postural Control in Constipation-Predominant Irritable Bowel Syndrome
This cross-sectional, observational, controlled comparative study aims to investigate the relationship between interoception and postural control in individuals with constipation-predominant irritable bowel syndrome (IBS-C) and…
- Trial name
- NCT07870915
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Chronic Stroke Patients
Mindfulness-Based Stress Reduction for Emotional Recovery After Stroke
The goal of this pilot study is to examine the feasibility, acceptability, and preliminary effects of mindfulness-based stress reduction (MBSR) on interoception (your understanding of your body's internal senses), emotional…
- Trial name
- NCT07491861
- Testing
- Mindfulness-Based Stress Reduction (MBSR)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- HealthPartners Institute
Bodily Self-Consciousness, Interoception
Hyperventilation Effects on Bodily Self-Consciousness
This study examines how voluntary fast, deep breathing (hyperventilation) affects the way healthy adults perceive their own body.
- Conditions
- Bodily Self-Consciousness, Interoception, Healthy Volunteers
- Trial name
- HYPERSELF (NCT07769710)
- Testing
- Voluntary hyperventilation (guided paced breathing), Normal spontaneous breathing (within-subject control), Synchronous respiratory-visual VR feedback
- Where
- Switzerland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Fribourg
Anorexia Nervosa, Body Image Disturbance
Interoceptive Mechanisms of Body Image Disturbance in Anorexia Nervosa
The proposed study utilizes a randomized experimental therapeutics design to test a mechanistic framework linking interoceptive processing and disturbed body image, with the purpose of informing the development of future…
- Conditions
- Anorexia Nervosa, Body Image Disturbance, Interoception
- Trial name
- NCT06332963
- Testing
- Floatation-REST, IFT, EFT
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Depression, Postpartum
Multimodal Biomarkers and Precision TMS for Postpartum Depression
The purpose of this study is to identify multimodal biological markers associated with postpartum depression (PPD) and to evaluate the effectiveness of precision brain stimulation treatment.
- Trial name
- MOTHER-TMS (NCT07757815)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- 2 sites in Macau
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- University of Macau
Duchenne / Becker Muscular Dystrophy, Osteogenesis Imperfecta (OI)
Social Cognition in Dystrophinopathies and Neurodevelopmental Disorders
The primary aim of this observational study is to investigate specific aspects of social cognition in dystrophinopathies. Body awareness, interpersonal distance and emotional processing will be measured in a sample of patients…
- Conditions
- Duchenne / Becker Muscular Dystrophy, Osteogenesis Imperfecta (OI), Social Cognition
- Trial name
- NCT06874166
- Testing
- Electroencephalography (EEG), Social Cognition Tasks
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Obesity
Interoception and Illness Perception Before and After Bariatric Surgery: Impact on Disordered Eating (Interoceptiv-BAR)
Obesity is associated with alterations in the perception and interpretation of internal bodily signals (interoception), which may influence eating behaviors, emotional regulation, and long-term weight outcomes.
- Trial name
- NCT07594275
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Interoception, Congenital Heart Disease
Interoceptive Intervention for Congenital Heart Disease
Adults living with congenital heart disease (CHD) commonly experience physical symptoms alongside emotional and social challenges, which can affect wellbeing and health-related quality of life.
- Trial name
- NCT07697755
- Testing
- Interoceptive-Based Group Intervention
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- University of Glasgow
Restless Legs Syndrome
Functional Connectivity of the Interoceptive Network in RLS
Restless Legs Syndrome (RLS) is a sensorimotor disorder primarily characterized by an irresistible urge to move the legs while at rest.
- Trial name
- IntoRLS (NCT07001891)
- Testing
- Clinical assessment, auto-questionnaires (PSQI, ISI, ESS and HADS), Ecological Momentary Assessment (EMA)
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Chronic Pain, Persistent Pain
Pleasant Touch Perception in Persistent Pain.
The goal of this observational study is to learn how individuals with chronic pain experience pleasant touch and how often they are exposed to such touch in their daily lives.
- Trial name
- NCT07551687
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Göteborg University
Healthy
BreatheWell: Train Your Breathing, Relax Your Body, Open Your Mind
The goal of this study is to determine whether tasks related to breathing training (daily inspiratory muscle training (IMT) and increased access to health data/awareness) performed for 12 weeks leads to positive changes in mental…
- Trial name
- NCT06920407
- Testing
- Breathing training device (Inspiratory Muscle Training), Oura Ring
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles