Clinical trials: Interscalene Brachial Plexus Block
Pain, Postoperative
Analgesic Efficacy of Interscalene Nerve Block Versus Local Infiltration Analgesia Following Total Shoulder Arthroplasty
Total shoulder arthroplasty (TSA) is considered to be a major surgical procedure resulting in severe postoperative pain, especially in the first 48 hours after surgery.
- Trial name
- NCT02876055
- Testing
- Single shot interscalene nerve block, Continuous interscalene nerve block, Local Infiltration Analgesia (LIA)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Pain, Shoulder Arthroscopy
Interscalene Block With Low-dose IV vs. Perineural Dexamethasone for Shoulder Arthroscopy
Many patients undergoing ambulatory shoulder arthroscopy experience moderate to severe pain after surgery. Finding ways to minimize postoperative pain are ideal.
- Trial name
- Dex ISB (NCT02506660)
- Testing
- Bupivacaine, Perineural dexamethasone, Intravenous dexamethasone
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Hospital for Special Surgery, New York
Shoulder Arthroscopy, Interscalene Block
Effect of Local Anesthetic Dose on Interscalene Block
The purpose of this study is to determine if a decrease in the standard volume of local anesthetic used to numb your shoulder area before shoulder arthroscopy will provide adequate anesthesia for the procedure and decrease the…
- Trial name
- Low Dose ISB (NCT01701115)
- Testing
- Low Dose (20 ml) Local Anesthetic Volume for Interscalene Block, Control Dose (40 mL) Local Anesthetic Volume for Interscalene Block, Low Dose (20 mL) Local Anesthetic (Mepivacaine:Bupivacaine)
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Surgery, Shoulder Impingement
Pupillary Pain Index to Evaluate Interscalene Block and Postoperative Pain in Patients Underwent Shoulder Surgery
When an individual encounters nociceptive pain stimuli, the pupil dilates in a unique manner known as Pupil reflex dilation (PRD).The degree of pupillary reflex dilatation can be further quantified into an objective parameter…
- Trial name
- NCT05590767
- Testing
- Patients scheduled to undergo shoulder rotators repair surgery
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Paresis
Bupivacaine Versus Ropivacaine on Diaphragmatic Motility and Ventilatory Function
Background: Outpatient continuous interscalene brachial plexus blocks are used to control pain after shoulder surgery, with infusions of 0.125% bupivacaine or 0.2% ropivacaine.
- Trial name
- NCT02059070
- Testing
- Ropivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Anesthesiology WSU/DMC-NorthStar
Joint Disease, Pain
Interscalene Block Versus Superior Trunk Block
Sparing the phrenic nerve by administering ultrasound-guided low volume superior trunk block (STB) and interscalene block (ISB) for arthroscopic shoulder surgery (labral repair, stabilization, rotator cuff repair).
- Conditions
- Joint Disease, Pain, Pain, Acute, Pain, Chronic
- Trial name
- STB (NCT03272139)
- Testing
- Bupivacaine, Ultrasound
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Hospital for Special Surgery, New York
Shoulder Pain, Rotator Cuff Tear
Efficacy of Interscalene Brachial Plexus Block With Liposomal Bupivacaine for Arthroscopic Shoulder Surgery
The purpose of this study is to compare the quality and duration of pain relief after shoulder surgery provided by a single injection of liposomal bupivacaine versus standard bupivacaine when administered as an interscalene…
- Trial name
- NCT01977352
- Testing
- Liposomal bupivacaine, Bupivacaine 0.25%
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Anesthesia, Local
Analgesia Duration of Dexamethasone, Buprenorphine, or Clonidine With Ropivacaine for Interscalene Nerve Block
This is a prospective randomized controlled triple-masked study looking at the duration of nerve block analgesia when using the listed adjuvants (dexamethasone, buprenorphine and clonidine) plus ropivacaine versus plain…
- Trial name
- NCT03117140
- Testing
- Ropivacaine 0.75%, Ropivacaine 0.75% + 300 mcg Buprenorphine, Ropivacaine 0.75% + 75 mcg clonidine
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Melinda Seering
Postoperative Pain, Adverse Effects
Continuous Interscalene Block Results in Superior Recovery Throughout the First Postoperative Week
The investigators undertook this prospective, randomized trial to compare the recovery profile throughout the first postoperative week in patients receiving continuous (CISB) interscalene brachial plexus block, single injection…
- Trial name
- NCT01881776
- Testing
- ISB
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Pain, Postoperative, Brachial Plexus Block
Liposomal Bupivacaine Single-Injection Interscalene Block vs. Continuous Interscalene Block for Primary Total Shoulder Arthroplasty
This study aims to assess analgesia efficacy between liposomal bupivacaine single injection interscalene blockade vs. continuous interscalene nerve block for patients undergoing primary total shoulder arthroplasty.
- Trial name
- NCT05005260
- Testing
- Bupivacaine HCl, Liposomal bupivacaine + Bupivacaine Hcl 0.5% Inj
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Mayo Clinic
Shoulder Arthroplasty
Interscalene Block With Liposomal Bupivacaine vs. Interscalene Block With Bupivacaine and Adjuvants
The purpose of this study is to determine whether the use of plain bupivacaine with common adjuvants for interscalene block (ISB) provides non-inferior analgesic results compared to the use of liposomal bupivacaine for ISB, in…
- Trial name
- NCT03845894
- Testing
- Liposomal bupivacaine, Bupivacaine with adjuvants
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Shoulder Arthroscopy
Pulmonary Function and Interscalene Block
The objective of our study is to compare the degree of phrenic nerve blockade after interscalene block using 0.1% ropivacaine or 0.2% ropivacaine.
- Trial name
- NCT02181296
- Testing
- ropivacaine
- Volunteers
- 50 people
- Sponsor
- University of Pennsylvania
Shoulder Pain
Dexmedetomidine vs Propofol TIVA (Total Intravenous Anesthesia) and Interscalene Block
The standard hospital procedure calls for the patient to undergo Interscalene block under ultrasound with or without nerve stimulation guidance prior to going to operating room (OR).
- Trial name
- TIVA (NCT02469961)
- Testing
- Dexmedetomidine, Propofol, Interscalene block
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Maimonides Medical Center
Rotator Cuff Tear, Pain, Postoperative
Single Shot Liposomal Bupivicaine in Rotator Cuff Surgery
This document is a protocol for a human research study. This study is to be conducted according to United States standards of Good Clinical Practice in accordance with applicable Federal regulations and institutional research…
- Trial name
- NCT03822182
- Testing
- liposomal bupivicaine, Dexamethasone
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Indiana University
Phrenic Nerve Paralysis
Evaluation of Diaphragm Movement After an Interscalene Block
The purpose of this study is to evaluate the movement of the diaphragm after an interscalene block with liposome bupivacaine (LB) compared to interscalene block (IB) with bupivacaine.
- Trial name
- NCT03636542
- Testing
- liposomal bupivacaine, bupivacaine
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Minnesota
Rotator Cuff Injury
Interscalene Brachial Plexus Block Combined With Suprascapular Nerve Block
The investigators compared the results of sono-guided interscalene brachial plexus block (ISB) combined with arthroscopy-guided suprascapular nerve block (SSNB) with those of ISB alone within the first 48 h after arthroscopic…
- Trial name
- NCT02424630
- Testing
- Ultrasound-guided ISB, Arthroscopy-guided SSNB, Ropivacaine
- Volunteers
- 52 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Pain
Intravenous Dexamethasone to Increase the Analgesic Duration of Interscalene Block
Interscalene brachial plexus block provides excellent but time limited analgesia. Intravenous dexamethasone increases the analgesic duration of a single-shot interscalene block with ropivacaine for shoulder arthroscopic surgery.
- Trial name
- NCT02412657
- Testing
- Dexamethasone, Normal Saline
- Where
- 3 sites in Canada
- Volunteers
- 75 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Shoulder Pain
Liposomal Bupivacaine vs Dexamethasone ISB
In this study, patients receiving shoulder arthroscopy will receive an interscalene block for pain management containing either liposomal bupivacaine and standard bupivacaine or standard bupivacaine and dexamethasone.
- Trial name
- NCT04047446
- Testing
- Exparel 133 MG Per 10 ML Injection, Dexamethasone
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- Hospital for Special Surgery, New York
Opioid Use, Unspecified
the Analgesic Duration of Dexmedetomidine Compared to Dexamethasone as Adjuncts to Single Shot Interscalene Block
The purpose of the study is to determine if perineural dexmedetomidine can provide increased prolongation of analgesia when compared to perineural dexamethasone in patients receiving regional block for shoulder surgery.
- Trial name
- NCT02653144
- Testing
- Ropivacaine, Dexmedetomidine, Dexamethasone
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Montefiore Medical Center
Post-operative Pain
Initial Local Anesthetic Dose With Continuous Interscalene Analgesia
Objective: To determine a minimally effective initial local anesthetic bolus required to provide satisfactory analgesia using continuous brachial plexus infusion following arthroscopic shoulder surgery using a double-blind…
- Trial name
- NCT00672100
- Testing
- Ropivacaine
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- Corewell Health East