Clinical trials: Interstitial Cystitis/Bladder Pain Syndrome
Interstitial Cystitis, Bladder Pain Syndrome
Biopsychosocial and Conventional Approach in Bladder Pain Syndrome
The aim of the present study is to compare the effects of biopsychosocial and conventional approach on symptom severity, pain parameters (pain intensity and pain cognitions), disability, psychological distress and quality of life…
- Trial name
- NCT05155384
- Testing
- Pain Neuroscience Education, Relaxation exercises, Cognition target exercise
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hacettepe University
Interstitial Cystitis, Bladder Pain Syndrome
Clinical Trial Comparing Two Bladder Instillations for IC/BPS
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a condition that results in long-term bladder and pelvic pain. IC/BPS affects women more often than men. How the disorder develops is not completely known.
- Trial name
- NCT03463915
- Testing
- Bladder instillation WITH triamcinolone acetonide, Bladder instillation WITHOUT triamcinolone acetonide
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Olivia Cardenas-Trowers, M.D.
Bladder Pain Syndrome, Interstitial Cystitis
Intravesical Injection of Dextrose to Improve Lower Urinary Tract Symptoms Caused by Chronic Cystitis
The pathogenesis of bladder pain syndrome/interstitial cystitis (BPS/IC) is currently unclear. Scholars have put forward different hypotheses, including the function of the extracellular matrix surface of the glycosaminoglycan…
- Trial name
- NCT04821882
- Testing
- Dextrose
- Where
- Taiwan
- Volunteers
- 29 people
- Sponsor
- National Defense Medical Center, Taiwan
Interstitial Cystitis, Painful Bladder Syndrome
Physical Therapy in Women With Interstitial Cystitis
There are many different treatments that doctors recommend for patients with IC/PBS. Only a few research studies have been done to evaluate treatments given to patients.
- Trial name
- IC03 (NCT00733603)
- Testing
- Global Therapeutic Massages (GTM), Myofascial Tissue Manipulation (MTM)
- Where
- 11 sites in United States, Canada
- Volunteers
- 81 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Interstitial Cystitis, Chronic, Bladder Pain Syndrome
Evaluation of Response to Use of Intravesical Ozone Gas in Interstitial Cystitis /Bladder Pain Syndrome
Interstitial Cystitis / bladder pain syndrome (CI / BPS) is a debilitating pathology with a negative impact on the quality of life of affected individuals.
- Trial name
- NCT04789135
- Testing
- Ozone
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Anhembi Morumbi University
Bladder Pain Syndrome, Interstitial Cystitis
Hypnosis for Bladder Pain Syndrome
This is a pilot randomized control trial of 30 women with interstitial cystitis/bladder pain syndrome to determine the feasibility of delivering a hypnosis intervention or usual care on bladder pain (primary outcome) and cerebral…
- Trial name
- NCT04010513
- Testing
- Hypnosis, Standard of Care
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Pennsylvania
Interstitial Cystitis Bladder Pain Syndromes
PTNS Versus Sham Efficacy in Treatment of BPS
This is a prospective, single center, double-blind, randomized, controlled trial comparing the efficacy of percutaneous tibial nerve stimulation to sham in the treatment of Bladder Pain Syndrome/Interstitial Cystitis (BPS/IC)…
- Trial name
- NCT02747420
- Testing
- NURO TM
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- NYU Langone Health
Interstitial Cystitis, Bladder Pain Syndrome
The CBD-IC Randomized Controlled Trial: Evaluation of Hemp Cannabidiol SuppositoRies for Pain and Urinary SymptOms in INterstitial Cystitis (CHRONIC)
This study seeks to exploit bladder cannabidiol receptors as a therapeutic drug target by conducting a double-masked, placebo-controlled randomized trial evaluating the effects of vaginal hemp cannabidiol (CBD) suppositories on…
- Trial name
- CHRONIC (NCT04349930)
- Testing
- Cannabidiol vaginal suppository
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of New Mexico
Bladder Pain Syndrome, Pentosan Polysulfate
Efficacy Study of Pentosan Polysulfate Sodium,Hydrodistension and Combination Therapy for Bladder Pain Syndrome
The efficacy of pentosan polysulfate sodium, hydrodistension and combination therapy in patients with bladder pain syndrome.
- Conditions
- Bladder Pain Syndrome, Pentosan Polysulfate, Hydrodistension
- Trial name
- NCT01895153
- Where
- South Korea
- Volunteers
- 91 people
- Sponsor
- Samsung Medical Center
Urinary Frequency/Urgency, Bladder Irritable
Mirabegron for the Treatment of Pain Motivated Urinary Frequency and Urgency in Women
The specific purpose of this study is to provide objective data in prospective open label design (n=40) to support the use of Mirabegron as a treatment for pain related urinary frequency and urgency.
- Conditions
- Urinary Frequency/Urgency, Bladder Irritable, Bladder Pain Syndrome
- Trial name
- NCT02981459
- Testing
- Mirabegron
- Where
- United States
- Sponsor
- State University of New York at Buffalo
Bladder Pain Syndrome
The Safety and Efficacy of Gefapixant (AF-219/MK-7264) in Female Participants With Interstitial Cystitis /Bladder Pain Syndrome (MK-7264-005)
The purpose of this study is to assess the efficacy of gefapixant (AF-219/MK-7264) in female participants with moderate to severe pain associated with interstitial cystitis/bladder pain syndrome (IC/BPS) after 4 weeks of…
- Trial name
- NCT01569438
- Testing
- Gefapixant
- Where
- 41 sites in United States
- Volunteers
- 107 people
- Sponsor
- Afferent Pharmaceuticals, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Chronic Prostatitis With Chronic Pelvic Pain Syndrome, Chronic Bacterial Prostatitis
Diagnostic Challenges in IC (and Male CPPS)
The etiology and pathogenesis of interstitial cystitis (IC) and its related condition in men, chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) has remained elusive.
- Conditions
- Chronic Prostatitis With Chronic Pelvic Pain Syndrome, Chronic Bacterial Prostatitis, Asymptomatic Inflammatory Prostatitis, Painful Bladder Syndrome
- Trial name
- NCT00672087
- Testing
- Genomic and proteomic biomarker discovery
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Prolapse, Urinary Incontinence
What is the Prevalence of Female Pelvic Floor Disorders in Minnesota?
To determine the prevalence of pelvic organ prolapse and urinary incontinence among women in Minnesota using a short web-based self-administered questionnaire.
- Conditions
- Prolapse, Urinary Incontinence, Fecal Incontinence, Bladder Pain Syndrome
- Trial name
- NCT03536221
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Interstitial Cystitis, Bladder Pain Syndrome
Platelet Enriched Plasma for Treatment of Interstitial Cystitis
A prospective randomized trial will be conducted aiming at evaluation the efficacy and safety of platelet enriched plasma for management of bladder pain syndrome .
- Conditions
- Interstitial Cystitis, Bladder Pain Syndrome, Platelet Enriched Plasma
- Trial name
- NCT04118946
- Testing
- platelet enriched plasma
- Where
- Egypt
- Volunteers
- 33 people
- Sponsor
- Mansoura University
Interstitial Cystitis, Bladder Pain Syndrome
Comparing the Effect of Fulguration Versus Fulguration and Hydrodistension in Interstitial Cystitis/Bladder Pain Syndrome
This study is a randomized controlled trial. Subject population is adult patients with Hunner-type interstitial cystitis. The objective of this study is to compare the therapeutic effect between the two surgical modality; TUF…
- Trial name
- NCT03987594
- Testing
- Transurethral fulguration of the Hunner lesion, Combination treatment of bladder hydrodistension and transurethral fulguration of the Hunner lesion
- Where
- South Korea
- Volunteers
- 55 people
- Sponsor
- Yonsei University
Interstitial Cystitis, Painful Bladder Syndrome
OXN PR vs Placebo in Opioid-naive Subjects Suffering From Severe Pain Due to Bladder Pain Syndrome (BPS)
The study compares the analgesic efficacy of OXN PR vs placebo in opioid-naive subjects suffering from severe pain due to Bladder Pain Syndrome.
- Conditions
- Interstitial Cystitis, Painful Bladder Syndrome, Pain
- Trial name
- NCT01197261
- Testing
- Oxycodone naloxone prolonged release tablets
- Where
- 5 sites in Czechia, Germany and 3 more
- Volunteers
- 120 people
- Sponsor
- Mundipharma Research GmbH & Co KG
Interstitial Cystitis, Bladder Pain Syndrome
Efficacy and Safety of 2 Doses of AQX-1125 in Subjects With Interstitial Cystitis / Bladder Pain Syndrome
This study evaluates the effects of two doses of oral AQX-1125 on bladder pain and other urinary symptoms in subjects with interstitial cystitis/bladder pain syndrome.
- Conditions
- Interstitial Cystitis, Bladder Pain Syndrome, Painful Bladder Syndrome, Chronic Interstitial Cystitis
- Trial name
- LEADERSHIP 301 (NCT02858453)
- Testing
- AQX-1125 100 mg, AQX-1125 200 mg
- Where
- 120 sites in United States, Belgium and 10 more
- Volunteers
- 433 people
- Sponsor
- Aquinox Pharmaceuticals (Canada) Inc.
Bladder Pain Syndrome
Comparison of the Efficacy Between Transurethral Coagulation and Transurethral Resection of Ulcer in Bladder Pain Syndrome Patients
On the EAU (European Association of Urology) guidelines, the ulcer type bladder pain syndrome (BPS) should be treated with transurethral resection (TUR) or coagulation (TUC) of ulcer.
- Trial name
- NCT01963988
- Testing
- Transurethral Coagulation (TUC), Transurethral Resection(TUR)
- Where
- South Korea
- Volunteers
- 126 people
- Sponsor
- Samsung Medical Center
Interstitial Cystitis, Bladder Pain Syndrome
Efficacy and Safety of AQX-1125 in IC/BPS
The primary objective of this study is to evaluate the effect of 6 weeks of treatment with once daily administration of AQX-1125 compared to placebo on average daily pain in subjects with interstitial cystitis/bladder pain…
- Trial name
- LEADERSHIP (NCT01882543)
- Testing
- AQX-1125
- Where
- 29 sites in United States, Canada
- Volunteers
- 69 people
- Sponsor
- Aquinox Pharmaceuticals (Canada) Inc.
Prostatitis, Chronic Prostatitis
Microbiome of Urologic Chronic Pelvic Pain Syndrome
This research is being done to learn more about the bacteria that live in the genito-urinary tract in subjects with urologic chronic pelvic pain syndrome (UCPPS).
- Conditions
- Prostatitis, Chronic Prostatitis, Interstitial Cystitis, Painful Bladder Syndrome
- Trial name
- NCT03027076
- Testing
- Genitourinary Specimen Collection, Collect midstream urine samples
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University