Clinical trials: Interstitial Cystitis/Painful Bladder Syndrome
Bladder Pain Syndrome, Interstitial Cystitis
Diagnosis of Bladder Pain Syndrome / Interstitial Cystitis
To identify new, simple and reliable biomarkers for bladder pain syndrome/interstitial cystitis (BPS/IC) for diagnosis of this disease.
- Conditions
- Bladder Pain Syndrome, Interstitial Cystitis, Overactive Bladder
- Trial name
- NCT03023241
- Testing
- biopsy
- Where
- Switzerland
- Volunteers
- 300 people
- Sponsor
- Cantonal Hospital, Frauenfeld
Interstitial Cystitis
Therapeutic Effects of Endoscopic Ablation of Hunner Lesions in Interstitial Cystitis/ Bladder Pain Syndrome Patients
efficacy of endoscopic ablation of Hunner lesions in patients with IC/BPS and the characteristics of HLs based on a long-term follow-up
- Trial name
- NCT03468530
- Testing
- Transurethral ablation
- Where
- South Korea
- Volunteers
- 442 people
- Sponsor
- Samsung Medical Center
Painful Bladder Syndrome, Interstitial Cystitis
Study of URG101 in Painful Bladder Syndrome and Interstitial Cystitis
A double-blind, placebo-controlled study to evaluate changes in pain, urgency and urinary frequency following administration of URG101 compared to placebo.
- Conditions
- Painful Bladder Syndrome, Interstitial Cystitis, Bladder Pain Syndrome
- Trial name
- NCT00517868
- Testing
- URG101
- Where
- 6 sites in United States
- Volunteers
- 28 people
- Sponsor
- Urigen
Interstitial Cystitis
Platelet Activating Factor Stability in Urine
The investigator's hypothesis is that smoking induces inflammation in the bladder wall. This may predispose to the development of Interstitial cystitis(IC) / bladder pain syndrome(BPS).
- Trial name
- NCT03103477
- Testing
- Urine stability
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- St. Louis University
Cystitis, Interstitial, Ulcer
A Safety and Efficacy Study of LiRIS® in Females With Interstitial Cystitis With Hunner's Lesions
This is a safety and efficacy study of LiRIS® in females with interstitial cystitis with Hunner's lesions.
- Trial name
- NCT02395042
- Testing
- LiRIS®
- Where
- 19 sites in United States, Canada
- Volunteers
- 59 people
- Sponsor
- Allergan
Vulvodynia
A Trial of Intravesical Therapy for Interstitial Cystitis in Patients With Generalized Vulvodynia
In order to investigate whether the pain in women with vulvodynia may represent bladder origin pain, we will be performing a diagnostic test for interstitial cystitis (IC) in women with generalized vulvodynia.
- Trial name
- VV/IC (NCT01048177)
- Testing
- Bladder instillation with heparin/ lidocaine
- Where
- United States
- Sponsor
- Scripps Health
Incontinence, Prostate Cancer
Urology Database to Evaluate Clinical Information and Improve Patient Care.
The purpose of initiating the Urology Database is to evaluate the outcomes of urology procedures and medical management to enhance the care and treatment of urology patients.
- Conditions
- Incontinence, Prostate Cancer, Interstitial Cystitis, Urinary Retention
- Trial name
- NCT00376298
- Where
- United States
- Volunteers
- 215 people
- Sponsor
- Kenneth Peters, MD
Cystitis, Interstitial, Painful Bladder Syndrome
Bladder Directed vs. Pelvic Floor Therapy in IC/BPS
Women with interstitial cystitis/bladder pain syndrome (IC/BPS) have debilitating urinary frequency and urgency, and chronic pelvic or bladder pain perceived to be related to the bladder.
- Trial name
- NCT02870738
- Testing
- Pelvic Floor Physical Therapy, Bladder Instillations
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Corewell Health East
Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS)
Study of BOTOX Injections to Assess Change in Disease Activity and Adverse Events in Adult Female Participants With Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS)
Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) is a chronic and debilitating urological complex of disorders characterized by symptoms of bladder pain or discomfort, mostly upon bladder filling, and often accompanied by…
- Trial name
- IC/BPS POC (NCT05141006)
- Testing
- BOTOX
- Where
- 43 sites in United States, Canada
- Volunteers
- 83 people
- Sponsor
- AbbVie
Bladder Diseases, Interstitial Cystitis
Efficacy of Amitriptyline for Painful Bladder Syndrome (PBS)
This is a randomized clinical trial study to test the efficacy and safety of amitriptyline in the treatment of patients newly diagnosed with painful bladder syndrome (PBS).
- Trial name
- IC01 (NCT00124306)
- Testing
- Amitriptyline
- Where
- 10 sites in United States, Canada
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Interstitial Cystitis
Intravesical Liposomes for Ulcerative Cystitis
The objective is to instill liposomes reconstituted with sterile water into the bladder as a compassionate use treatment in one patient with ulcerative interstitial cystitis (IC).
- Trial name
- NCT01083979
- Testing
- Liposomes
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Kenneth Peters, MD
Interstitial Cystitis, Bladder Pain Syndrome
Intravesical Ozone Therapy for Interstitial Cystitis/Bladder Pain Syndrome
This randomized, double-blind, placebo-controlled trial evaluated the efficacy and safety of intravesical ozone therapy in 60 patients with interstitial cystitis (IC).
- Trial name
- NCT06863220
- Testing
- Intravesical Ozone Therapy, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Cystitis, Interstitial
Treatment of Interstitial Cystitis/Painful Bladder Syndrome Using Alternative Techniques: Exercise, Meditation, Tai Chi
Complementary and alternative medicine (CAM) is the term for medical products and/or practices that are not part of the current standard of care.
- Trial name
- NCT00661050
- Testing
- Alternative Medicine, Tai Chi instruction and class participation or walking exercise and sitting meditation
- Where
- United States
- Sponsor
- Stanford University
Hunner Type Interstitial Cystitis
A Clinical Study of ONO-1110 in Patients With Hunner Type Interstitial Cystitis
To Evaluate the Efficacy and Safety of ONO-1110 in Patients with Hunner Type Interstitial Cystitis
- Trial name
- NCT06752603
- Testing
- ONO-1110
- Where
- 20 sites in Japan
- Volunteers
- 57 people
- Sponsor
- Ono Pharmaceutical Co., Ltd.
Interstitial Cystitis
Safety, Tolerability and Efficacy Study of LiRIS® 400 mg in Women With Interstitial Cystitis
The purposes of the study is to determine if LiRIS®, an investigational drug-delivery system, is safe and tolerable in women with Interstitial Cystitis (IC), and to evaluate any change in IC symptoms following LiRIS…
- Trial name
- NCT01824303
- Testing
- LiRIS 400 mg
- Where
- 17 sites in United States, Canada
- Volunteers
- 31 people
- Sponsor
- Allergan
Painful Bladder Syndrome
A Comparison of Electrical Ilioinguinal Nerve Stimulation With Intravesical Irrigation for Bladder Pain Syndrome
The purpose of this study is to determine whether electrical ilioinguinal nerve stimulation (EINS) is more effective than intravesical irrigation (II) in treating bladder pain syndrome.
- Trial name
- NCT02856022
- Testing
- Electrical ilioinguinal nerve stimulation, Intravesical Irrigation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Institute of Acupuncture, Moxibustion and Meridian
Interstitial Cystitis
Observational Study of Hunner's Ulcer in Patient With Interstitial Cystitis/Bladder Pain Syndrome
The purpose of this study is to observe change of distribution pattern of Hunner's ulcer in patient with interstitial cystitis/bladder pain syndrome
- Trial name
- NCT02150811
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Asan Medical Center
IC - Interstitial Cystitis
Phenotyping Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) by Intravesical Contrast Enhanced - Magnetic Resonance Imaging (ICE-MRI) Bladder Permeability Assay
Each participant will be asked to participate in this research study which distinguishes different types of Interstitial Cystitis/Bladder Pain Syndrome. Research studies include only people who wish to participate.
- Trial name
- NCT05811377
- Testing
- Ferumoxytol, Gadobutrol
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Christopher J Chermansky, MD
Urinary Bladder Neoplasms, BCG-Induced Cystitis
Early vs Delayed Intravesical Blad-Care During BCG Therapy
Intravesical Bacillus Calmette-Guérin (BCG) therapy is the standard adjuvant treatment for patients with intermediate- and high-risk non-muscle-invasive bladder cancer (NMIBC).
- Trial name
- PRO-GAG (NCT07495072)
- Testing
- Hyaluronic Acid and Chondroitin Sulfate (Blad-Care™)
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- BLAD-HYA Group
Interstitial Cystitis
Intranasal Ketorolac Tromethamine (Sprix) for Acute Pain of Interstitial Cystitis Flare of Pain
Intranasal Ketorolac tromethamine has a potential role as a short term pain management tool for Interstitial Cystitis without the risk and undesirable effects of narcotics.
- Trial name
- NCT02000401
- Testing
- Ketorolac Tromethamine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Citrus Valley Medical Research, Inc.