Clinical trials: Interstitial Cystitis/Painful Bladder Syndrome
Painful Bladder Syndrome, Interstitial Cystitis
Acupuncture for Female IC/PBSyndrome and Its Effect on the Urinary Microbiome: A Randomized Controlled Trial
The investigators central hypothesis is that women with Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS) will benefit from acupuncture compared with sham treatment and acupuncture responders will have a differential…
- Trial name
- NCT02232282
- Testing
- standard acupuncture treatment
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Loyola University
Interstitial Cystitis, Levator Spasm
A Multidisciplinary, Multimodal Bundled Care Approach to Chronic Pelvic Pain
The goal of this clinical trial is to compare two different treatment patterns in patients with chronic bladder pain. The main questions the investigators are seeking to answer is if bladder pain improves before and after…
- Conditions
- Interstitial Cystitis, Levator Spasm, Bladder Pain Syndrome
- Trial name
- NCT05658874
- Testing
- Multimodal Bundle Drugs, Operative Cystoscopy, Behavioral health consultation/therapy
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Jocelyn Fitzgerald
Bladder Cancer, Prostate Cancer
Medtronic Hugo™ Robotic Assisted Surgery (RAS) System in Urologic Surgery (Expand URO)
This study will evaluate the safety and performance of the Medtronic Hugo™ RAS System when used for urologic RAS procedures.
- Conditions
- Bladder Cancer, Prostate Cancer, Kidney Cancer, Pelvic Tumor
- Trial name
- NCT05696444
- Testing
- RAS Prostatectomy, RAS Cystectomy, RAS Nephrectomy
- Where
- 6 sites in United States
- Volunteers
- 144 people
- Sponsor
- Medtronic - MITG
Interstitial Cystitis, Bladder Pain Syndrome
Transvaginal Botulinum Toxin A for Interstitial Cystitis / Bladder Pain Syndrome
Interstitial cystitis / bladder pain syndrome (IC/BPS) is a debilitating condition that affects millions of women in the United States.
- Trial name
- T3STOPBPS (NCT05485207)
- Testing
- Transvaginal botulinum toxin A (BTA) injection
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Stanford University
Cystitis, Interstitial, Painful Bladder Syndrome
A Study to Determine the Role of Toll-like Receptor-4 Expression in Patients With Interstitial Cystitis/Bladder Pain Syndrome
This is a prospective pilot study, with a recruitment goal of 60 patients. Patients who are female, above the age of 18, and with a diagnosis of IC/BPS based on clinical criteria and O'Leary Sant ICPI and ICSI scores undergoing…
- Trial name
- NCT02868775
- Testing
- cystoscopy, bladder hydrodistention and bladder biopsy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Philadelphia Urosurgical Associates
Interstitial Cystitis, Bladder Pain Syndrome
Efficacy and Safety of 2 Doses of AQX-1125 in Subjects With Interstitial Cystitis / Bladder Pain Syndrome
This study evaluates the effects of two doses of oral AQX-1125 on bladder pain and other urinary symptoms in subjects with interstitial cystitis/bladder pain syndrome.
- Conditions
- Interstitial Cystitis, Bladder Pain Syndrome, Painful Bladder Syndrome, Chronic Interstitial Cystitis
- Trial name
- LEADERSHIP 301 (NCT02858453)
- Testing
- AQX-1125 100 mg, AQX-1125 200 mg
- Where
- 120 sites in United States, Belgium and 10 more
- Volunteers
- 433 people
- Sponsor
- Aquinox Pharmaceuticals (Canada) Inc.
Interstitial Cystitis
Interstitial Cystitis
Patients with interstitial cystitis who meet eligibility requirements will be randomized to one of four treatment arms (3 RTX, Placebo). Study drug is administered as a single instillation within the urinary bladder.
- Trial name
- NCT00056251
- Testing
- H&P; ECG; Blood tests; voiding diary; Cystoscopy
- Where
- 24 sites in United States
- Volunteers
- 150 people
- Sponsor
- ICOS Corporation
Cystitis, Interstitial, Dysmenorrhea
Chronic Pain Risk Associated With Menstrual Period Pain
The purpose of this study is to determine if some women with dysmenorrhea (painful periods) are at higher future risk of developing chronic pelvic pain (CPP) and if oral contraceptives (OC) can be used to reverse this chronic…
- Conditions
- Cystitis, Interstitial, Dysmenorrhea, Migraine Disorders, Pelvic Pain
- Trial name
- CRAMPP (NCT02214550)
- Testing
- cyclic microgestin 1/20, continuous microgestin 1/20
- Where
- United States
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Interstitial Cystitis
Genetic and Histopathologic Characteristics of Interstitial Cystitis
Genetic and Histopathologic Characteristics of Interstitial Cystitis
- Trial name
- NCT03523559
- Testing
- bladder tissue of Interstitial Cystitis and normal bladder tissue
- Where
- South Korea
- Volunteers
- 14 people
- Sponsor
- Samsung Medical Center
Vulvodynia
Relationship: Interstitial Cystitis & Vulvodynia-Part 2
The etiology of pain in women with IC is often difficult to identify resulting in unnecessary medical and surgical treatments (e.g. hysterectomies).
- Trial name
- NCT00751010
- Where
- United States
- Volunteers
- 127 people
- Sponsor
- Corewell Health East
Chronic Fatigue Syndrome, Fibromyalgia
Proteomics of Cerebrospinal Fluid in Chronic Fatigue Syndrome
The purpose of this study is: 1. To identify specific set of proteins in the cerebrospinal fluid (fluid surrounding the brain and the spinal cord), that are believed to be seen in Chronic fatigue syndrome (CFS) patients, but not…
- Conditions
- Chronic Fatigue Syndrome, Fibromyalgia, Gulf War Illness, Multiple Chemical Sensitivity
- Trial name
- NCT00810329
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Bladder Pain Syndrome, Interstitial Cystitis
Intravesical Injection of Dextrose to Improve Lower Urinary Tract Symptoms Caused by Chronic Cystitis
The pathogenesis of bladder pain syndrome/interstitial cystitis (BPS/IC) is currently unclear. Scholars have put forward different hypotheses, including the function of the extracellular matrix surface of the glycosaminoglycan…
- Trial name
- NCT04821882
- Testing
- Dextrose
- Where
- Taiwan
- Volunteers
- 29 people
- Sponsor
- National Defense Medical Center, Taiwan
Interstitial Cystitis
Interstitial Cystitis and Urinary pH
This is a pilot study to assess the correlation between urinary pH and Interstitial Cystitis (IC) pain, with emphasis placed on exploring the type and severity of pain.
- Trial name
- NCT03024619
- Testing
- Pain and Urinary pH
- Volunteers
- 20 people
- Sponsor
- St. Louis University
Healthy
Safety and Tolerability Study of the Taris Placebo System
The aim of this protocol is to evaluate the tolerability of the Taris placebo system for the development program and to provide key safety and tolerability data for the Taris platform.
- Trial name
- NCT01051336
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- TARIS Biomedical, Inc.
IC, Interstitial Cystitis and Bladder Pain Syndrome
The Study is Being Conducted to Find a New Treatment for Patients Suffering From Interstitial Cystitis Without Hunner's Lesions.
To evaluate the efficacy and safety of Neovasculgen in interstitial cystitis and the prevention of secondary bladder shrinkage with a decrease in its volume.
- Conditions
- IC, Interstitial Cystitis and Bladder Pain Syndrome, Interstitial Cystitis, Chronic
- Trial name
- NCT07391306
- Testing
- Neovasculgen®
- Where
- Russia
- Volunteers
- 180 people
- Sponsor
- JSC NextGen
Bladder Pain Syndrome, Pregabalin
Efficacy and Safety of Pregabalin Combined With Educational and Behavioral Intervention for Bladder Pain Syndrome/Interstitial Cystitis
Bladder pain syndrome/interstitial cystitis (IC/BPS) brings long-term pelvic pain, frequent urination and poor sleep quality, which severely lowers patients' daily life quality.
- Conditions
- Bladder Pain Syndrome, Pregabalin, Educational Behavioral Intervention, Urinary Urgency
- Trial name
- PEBI-ICBPS (NCT07752134)
- Testing
- Educational and Behavioral Management Program (EBMP), Pregabalin
- Volunteers
- 200 people
- Sponsor
- Beijing Tiantan Hospital
Bladder Pain Syndrome, Pentosan Polysulfate
Efficacy Study of Pentosan Polysulfate Sodium,Hydrodistension and Combination Therapy for Bladder Pain Syndrome
The efficacy of pentosan polysulfate sodium, hydrodistension and combination therapy in patients with bladder pain syndrome.
- Conditions
- Bladder Pain Syndrome, Pentosan Polysulfate, Hydrodistension
- Trial name
- NCT01895153
- Where
- South Korea
- Volunteers
- 91 people
- Sponsor
- Samsung Medical Center
Interstitial Cystitis and Bladder Pain Syndrome
Learning to THRIVE (L2T) Program Pilot
This pilot study evaluated the feasibility and potential effects of Learning to THRIVE (L2T), a six-week online educational self-management program for adults who self-identified as women or female and had interstitial…
- Trial name
- L2T (NCT07797010)
- Testing
- Learning to THRIVE (L2T) Program
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Indianapolis
Interstitial Cystitis, Sacroiliac Joint Somatic Dysfunction
Osteopathic Manipulation for Female Interstitial Cystitis Patients With Sacroiliac Joint Dysfunction
The proposed study will evaluate the effectiveness of Osteopathic manipulation of the sacro-iliac joint (SIJ) and the lumbar spine in symptomatic female interstitial cystitis (IC) patients with sacro-iliac joint dysfunction.
- Trial name
- NCT01311479
- Testing
- Osteopathic Manipulation Therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Pelvic and Sexual Health Institute
Interstitial Cystitis, IC
Efficacy and Safety of Intravesical Instillations of Botulinum Toxin in TC-3 Gel in IC Patients
The investigators believe that this study is of importance of several aspects: 1. It evaluates a new mode of bladder instillation that may bypass the drawbacks of the current instillation mode. 2.
- Trial name
- NCT01997983
- Testing
- TC-3 Gel mixed with Botox (BTX)
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- UroGen Pharma Ltd.