Clinical trials: Intervention Condition
Emergencies
Comparison of Propofol-fentanyl and Midazolam-fentanyl for Conscious Sedation
Sixty patients who refer to the emergency ward and need any painful procedure in the ward are randomized into 2 groups. One group is sedated before the procedure using propofol-fentanyl and the other with midazolam-fentanyl, with…
- Trial name
- NCT01749579
- Testing
- Propofol, Midazolam, Fentanyl
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Tehran University of Medical Sciences
Coronary Artery Disease, Chronic Renal Failure
Coronary Rotational Atherectomy Elective vs. Bailout in Severely Calcified Lesions and Chronic Renal Failure
The current role of the rotational atherectomy is for non-dilatable coronary lesions and for severely calcified lesions that may interfere with optimal stent expansion.
- Trial name
- CRATER (NCT05353946)
- Testing
- Percutaneous coronary intervention (PCI)
- Where
- Spain
- Volunteers
- 124 people
- Sponsor
- Guillermo Galeote; MD, PhD
Sarcopenia, Gait Disorders in Old Age
A Double-blind, Placebo-controlled, Randomized INTerventional Clinical Trial (SARA-INT)
The main objective of the study is to evaluate the effect of two daily doses of BIO101 versus placebo on mobility function as measured by gait speed using the 400MW test.
- Conditions
- Sarcopenia, Gait Disorders in Old Age, Muscle Weakness
- Trial name
- SARA-INT (NCT03452488)
- Testing
- BIO101
- Where
- 22 sites in United States, Belgium
- Volunteers
- 233 people
- Sponsor
- Biophytis
Post-COVID / Long-COVID, POST-Covid 19
Effects of Hydrotherapy During Post-COVID-19 Rehabilitation
This randomized controlled study evaluates the effects of cold water hydrotherapy as an adjunct to standard rehabilitation in patients with Post-COVID Syndrome.
- Conditions
- Post-COVID / Long-COVID, POST-Covid 19, Post COVID Syndrome, Post-COVID Condition
- Trial name
- HydroCoVital A (NCT07013903)
- Testing
- Standard rehabilitation plus cold water hydrotherapy, Standard rehabilitation only
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Schön Klinik Berchtesgadener Land
Cardiovascular Disease
Mussel Intake and Vitamin D Status in Humans
A significant proportion of the United Kingdom population have inadequate levels of vitamin D in their blood. Vitamin D is a fat-soluble vitamin that is essential for the growth and maintenance of healthy bones through increasing…
- Trial name
- Mussel (NCT02982525)
- Testing
- No Mussels, One mussel portion, Two mussel portions
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Diabetes Mellitus, Type 2, Prediabetic State
Improving Physical Activity Through a mHealth Intervention in Cardio-metabolic Risk Patients
The goal of this study is to explore the effects of FeatForward on physical activity and cardio-metabolic risk factors. The study will be implemented as a 2-arm randomized controlled trial (RCT) comparing the effects of…
- Conditions
- Diabetes Mellitus, Type 2, Prediabetic State, Hypertension, Prehypertension
- Trial name
- NCT02551640
- Testing
- FeatForward App (on study smartphone)
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Massachusetts General Hospital
Rheumatoid Arthritis, Arthritis, Rheumatoid
Educational Intervention to Improve Patient-Physician Awareness of Cardiovascular Risk in Rheumatoid Arthritis.
This study will provide an educational intervention through means of a video to educate subjects on the risk of cardiovascular health on Rheumatoid arthritis.
- Trial name
- NCT03495791
- Testing
- YouTube Video
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Rush University Medical Center
End-Stage Renal Disease, Hemodialysis
Hemocontrol and Blood Pressure Control in Dialysis Patients
Volume overload contributes significantly to the pathogenesis of hypertension in hemodialysis patients. The Hemocontrol(HC)system (Gambro), which automatically adjusts ultrafiltration rate and dialysate conductivity according to…
- Trial name
- NCT00319774
- Testing
- Hemocontrol Biofeedback System
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Université de Montréal
Adolescent Problem Behavior, Truancy; Unsocialized
Substance Use Interventions for Truant Adolescents
This study evaluates a brief motivation-building intervention for parents and teens to reduce truancy and substance use. It is hypothesized that the motivational intervention will result in better outcomes compared to an…
- Conditions
- Adolescent Problem Behavior, Truancy; Unsocialized, Marijuana Abuse, Truancy; Socialized
- Trial name
- GOALS (NCT03655574)
- Testing
- Motivational + Family Check-up (MET+FCU), Psychoeducation
- Where
- 2 sites in United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Brown University
Evidence of an Intervention on Childhood BMI z Score
The Impact of an Intervention Taught by Trained Teachers on Childhood BMI z Score
The purpose of this study is to assess the effects of a six months nutrition intervention, delivered and taught by classroom teachers with in-service nutrition training, on the prevention of overweight and obesity among children…
- Trial name
- NCT01397123
- Testing
- Training teachers on healthier lifestyles
- Where
- Portugal
- Volunteers
- 464 people
- Sponsor
- University of Minho
Medication Adherence, Stroke
Improving Medication Adherence Through SMS (Short Messaging Service) in Adult Stroke Patients: a Randomised Controlled Behaviour Intervention Trial
The impact of medications used for secondary stroke prevention relies heavily upon patient adherence. Adherence is defined as "the extent to which a person's behavior - taking medication, following a diet, and/or executing…
- Trial name
- NCT01986023
- Testing
- SMS- Short Messaging Service
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Aga Khan University
Schizophrenia, Medical Complication
Adapting Critical Time Intervention to Support Inpatient Medical Care Transition
We are pursuing a pilot study to assess the feasibility and preliminary effectiveness of adapting a critical time intervention (CTI) approach for adults with schizophrenia who have been admitted for the inpatient treatment of…
- Trial name
- NCT03637296
- Testing
- Critical time intervention
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- New York State Psychiatric Institute
Childhood Obesity
Therapeutic Education Groups for Childhood Obesity
The goal of this clinical trial is to test the efficacy of an educational therapeutic intervention in treating obesity in a pediatric population.
- Trial name
- GET-Obesity (NCT06239662)
- Testing
- Therapeutic Group, Usual care
- Volunteers
- 318 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Coronary Artery Disease, Percutaneous Coronary Intervention
Cutting Balloon Predilation Prior to Abluminus Sirolimus-eluting Stent Implantation (CUT-DRESS).
Drug-eluting stents iterations has significantly improved the results of percutaneous revascularization among patients undergoing coronary revascularization thanks to thinner struts, more biocompatible polymer coatings and new…
- Conditions
- Coronary Artery Disease, Percutaneous Coronary Intervention, Cutting Balloon
- Trial name
- CUT-DRESS (NCT05801003)
- Testing
- Predilation with cutting balloon., Predilation with conventional balloon
- Where
- 3 sites in Spain
- Volunteers
- 96 people
- Sponsor
- Hospital Universitario La Fe
Respiratory Disease
HDDO-1801 Intervention Trial
A randomized, open-label, single-dose, 3-period, 6-sequence, 3-way crossover study
- Trial name
- NCT04097951
- Testing
- Combinations
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hyundai Pharmaceutical Co., LTD.
Obesity, Weight Loss
Impact of Group Size in Weight Loss Interventions
The present study will assess whether the size of treatment groups (groups of 10 vs. 30 participants) affects short- and long-term weight loss.
- Trial name
- NCT01165151
- Testing
- behavioral weight loss program
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Florida State University
Pain Measurement
Pain Assessment Via Force Measurement Using eEgg After Blockade of the Lumbar Facet Joints
The emotion Egg, or "eEgg" for short, is a sample series of a device for testing a new pain measurement method that is not yet on the market.
- Trial name
- SMeEgg (NCT05881551)
- Testing
- eEgg, NRS
- Where
- Germany
- Volunteers
- 53 people
- Sponsor
- University of Witten/Herdecke
Open-angle Glaucoma, Pseudoexfoliation Glaucoma
Vitamin Mix (B6, B9, B12, And Choline) For Glaucoma Patients
This study aims to determine whether a combination of vitamins (B6, B9, B12, and choline) can help protect the eyes of people with glaucoma and slow vision loss.
- Trial name
- IVMGS (NCT06885827)
- Testing
- Vitamin B-mix, Standard Care
- Where
- 2 sites in Sweden
- Volunteers
- 80 people
- Sponsor
- Karolinska Institutet
Ulcerative Colitis (UC)
A Long-Term Registry of Humira® (Adalimumab) in Patients With Moderately to Severely Active Ulcerative Colitis (UC)
This is a registry study to evaluate the long-term safety and effectiveness of adalimumab in patients with moderately to severely active UC who are treated as recommended in the product label.
- Trial name
- LEGACY (NCT01848561)
- Where
- 512 sites in United States, Australia and 19 more
- Volunteers
- 8,250 people
- Sponsor
- AbbVie
High Intensity Exercise, Normal Cognition
CYCLE-AD (CYcling to Cease or Limit the Effects of Alzheimer's Disease)
The overall goal of the CYCLE-AD trial is to determine the role of long-term, high intensity exercise in slowing or delaying the onset of cognitive and AD-related brain changes in e4 carriers.
- Conditions
- High Intensity Exercise, Normal Cognition, Exercise Intervention
- Trial name
- CYCLE-AD (NCT04748861)
- Testing
- Indoor Cycling (IC)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic