Clinical trials: Intervention Effectiveness
Primary and Secondary Immunodeficiency and Other Conditions Requiring Regular Administration of Octagam 5% or 10% IVIG
Non-Interventional Study on the Tolerability and Efficacy of IVIG
Non-Interventional Study on the Tolerability and Efficacy of octagam® 10%
- Trial name
- GAM 10-06 (NCT02303093)
- Testing
- Octagam IVIG 5% or 10%, Panzyga
- Where
- 38 sites in Austria, Canada and 3 more
- Volunteers
- 344 people
- Sponsor
- Octapharma
Metastatic Breast Cancer
European Treatment Patterns and Outcomes Associated With First-Line CDK4/6 Inhibition and Hormonal Therapies
A retrospective observational analysis of de-identified data from a multinational medical record review to describe patient characteristics, treatment patterns, and effectiveness of palbociclib + AI as first-line therapy among…
- Trial name
- EUCHARIS (NCT05043506)
- Testing
- Palbociclib + aromatase inhibitor, Aromatase inhibitor
- Where
- 64 sites in Austria, Belgium and 5 more
- Volunteers
- 1,939 people
- Sponsor
- Pfizer
Bone Loss in Jaw
Evaluation of Efficacy and Safety of Wishbone HA as Bone Graft Substitute, a Pre-market Clinical Investigation
Evaluation of efficacy and safety of Wishbone HA as bone graft substitute, a pre-market clinical investigation. Group1: Extraction Socket management Group 2: Sinus lift
- Trial name
- NCT04054219
- Testing
- Bone graft substitute
- Where
- Belgium
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Wishbone SA
Asthma, Asthma Patients
Fixed Triple Inhaled Combination in Asthmatic Patients in a Real-life Setting
The mainstay of asthma treatment are ICSs, mostly and usually combined with LABA. In the past decade LAMA had been accepted as an add-on treatment for patients on GINA treatment Steps 4 and 5.
- Conditions
- Asthma, Asthma Patients, Asthma Bronchiale
- Trial name
- STRENGTH (NCT06786767)
- Testing
- BDP/FF/G (Beclomethasone diprprionate, formoterol fumarate, glycopyrronium bromide) 172/5/9 μg
- Where
- 14 sites in Bulgaria
- Volunteers
- 281 people
- Sponsor
- Chiesi Bulgaria
Carcinoma, Hepatocellular, Metastatic Liver Cancer
Safety and Effectiveness of BioTraceIO Lite for Tissue Damage Assessment Following Liver Tissue Ablation Procedures
Clinical study planned to demonstrate that the BioTraceIO Lite, available post-procedure, is effective at estimating the area of tissue damage as measured on 24-hour post-procedure (T=24hrs) CECT scan and that it is safe, based…
- Trial name
- NCT04970212
- Testing
- BioTraceIO Lite
- Where
- 6 sites in United States
- Volunteers
- 65 people
- Sponsor
- Techsomed Medical Technologies LTD
Doctor-patient Communication Improvement
A Study of the Effect of Patient Education (Talking Health Together) in Improving Doctor-patient Communication
This study is being carried out to see if patients make the lifestyle changes or take their medication as instructed by their doctor during their visit as a result of the T.H.T. patient-education training.
- Trial name
- NCT00879736
- Testing
- THT PACE Training
- Where
- 5 sites in Canada
- Volunteers
- 322 people
- Sponsor
- AstraZeneca
Chronic Venous Disease
Chronic VEnous dIsorders maNagement and Treatment effectivenesS evaluaTion in Chronic vEnous Disease, an International Program
The primary objective of this study is to assess in real-life settings the effectiveness of conservative treatments on symptoms, signs and quality of life, in patients consulting for CVD
- Trial name
- VEIN STEP (NCT04574375)
- Where
- France
- Volunteers
- 6,419 people
- Sponsor
- Servier Affaires Médicales
Diabetes, Diabetes Mellitus, Type 1
Investigating the Safety and Effectiveness of Insulin Degludec in a Real World Population With Type 1 and 2 Diabetes Mellitus
This study is conducted in Europe. The aim of this non-interventional study is to investigate the safety and effectiveness of insulin degludec (Tresiba®) in a real world population with type 1 (T1DM) and 2 (T2DM) diabetes…
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- ReFLeCT (NCT02392117)
- Testing
- insulin degludec
- Where
- 8 sites in Denmark, Germany and 6 more
- Volunteers
- 1,262 people
- Sponsor
- Novo Nordisk A/S
Surgical Skin Preparation, Surgical Procedure, Unspecified
In Vivo Preoperative Skin Preparation Efficacy Study Within a Defined Product Coverage Area
This study evaluates reduction of resident flora produced by the test product within a defined prepped area of skin.
- Trial name
- NCT03681990
- Testing
- 3M CHG/IPA Prep
- Where
- Romania
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Solventum US LLC
Periorbital Hyperpigmentation (Dark Circles)
A Study to Determine the Safety & Efficacy of Autologous Human Platelet Lysate (HPL) in Treatment of Dark Circles
This is a multicentre, open label, randomized, pilot study to evalute safety and efficacy of Human Platelet Lysate (HPL) in subjects with Periorbital Hyperpigmentation.
- Trial name
- NCT01644448
- Testing
- Autologous Human Platelet Lysate, Standard Therapy
- Where
- India
- Volunteers
- 20 people
- Sponsor
- Kasiak Research Pvt. Ltd.
Hepatitis C, Chronic
An Observational Study of Dual and Triple Therapies Based on Pegasys (Peginterferon Alfa-2a) in Patients With Chronic Hepatitis C
This multi-center, observational study will evaluate the efficacy and safety of dual and triple therapies based on Pegasys (peginterferon alfa-2a) in patients with chronic hepatitis C.
- Trial name
- NCT01604291
- Where
- 21 sites in Israel
- Volunteers
- 991 people
- Sponsor
- Hoffmann-La Roche
Pain
Evaluation of DEX-IN During Outpatient Procedures
The primary objective of this study is to evaluate the analgesic efficacy of DEX-IN compared with placebo and active control (fentanyl), in subjects undergoing painful outpatient and office based procedures.
- Trial name
- NCT03348423
- Testing
- DEX-IN, Fentanyl
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Baudax Bio
Open Angle Glaucoma
Study of the CycloPen Micro-Interventional System and Long-Term Clinical Outcomes
This observational study will enroll adults with open angle glaucoma (OAG) who had surgery to reduce intraocular pressure (IOP) using the CycloPen Micro-Interventional System.
- Trial name
- CREST (NCT05506423)
- Testing
- CycloPen Cyclodialysis System
- Where
- 16 sites in United States, Panama
- Volunteers
- 300 people
- Sponsor
- Iantrek, Inc.
Postoperative Pain
Safety and Efficacy of Tapentadol Immediate Release (IR) and Oxycodone IR for Treatment of Acute Post-op Pain Following Elective Arthroscopic (Surgery Using a Thin Flexible Scope) Shoulder Surgery
The purpose of this study is to evaluate how tapentadol immediate release (IR) and oxycodone IR treat moderate to severe post-operative pain after elective arthroscopic shoulder surgery.
- Trial name
- NCT00814580
- Testing
- Tapentadol IR, Oxycodone IR
- Volunteers
- 382 people
- Sponsor
- Ortho-McNeil Janssen Scientific Affairs, LLC
Non-inflammatory Degenerative Joint Disease, Osteoarthritis
Study to Evaluate the Safety and Effectiveness of REAL INTELLIGENCE™ CORI™ in Unicondylar Knee Arthroplasty (UKA) Procedures
This is a prospective study to demonstrate the safety and effectiveness of CORI and to register CORI in China mainland.
- Conditions
- Non-inflammatory Degenerative Joint Disease, Osteoarthritis, Avascular Necrosis, Requires Correction of Functional Deformity
- Trial name
- CORI RCT UKA (NCT04797897)
- Testing
- CORI, Conventional
- Where
- 3 sites in Australia, Hong Kong and 1 more
- Volunteers
- 4 people
- Sponsor
- Smith & Nephew, Inc.
Pulmonary Disease, Chronic Obstructive
Effectiveness of Tiotropium + Olodaterol Versus Inhaled Corticosteroids (ICS) + Long-acting β2-agonists (LABA) Among COPD Patients in Taiwan
The real world study aims to assess effectiveness and safety profile between tiotropium/olodaterol (Tio/Olo) and inhaled corticosteroids(ICS) / Long-acting β2-agonists (LABA) in patients with chronic obstructive pulmonary disease…
- Trial name
- NCT05402020
- Testing
- Tiotropium (Tio), Inhaled corticosteroids (ICS), Olodaterol (Olo)
- Where
- China
- Volunteers
- 17,018 people
- Sponsor
- Boehringer Ingelheim
Skin Breakdown
Study to Demonstrate the Efficacy and Safety of Convatec ConvaFoam™ Silicone, ConvaFoam™ Border and ConvaFoam™ Non-adhesive Dressings to Protect Against Skin Breakdown
A prospective, multi centre, interventional, non-comparator, open label study to demonstrate the efficacy, safety, and performance of ConvaFoam™ Silicone, ConvaFoam™ Border and ConvaFoam™ Non-adhesive to protect against skin…
- Trial name
- DONNA (NCT05902182)
- Testing
- ConvaFoam
- Volunteers
- 130 people
- Sponsor
- ConvaTec Inc.
Chronic Spontaneous Urticaria
Remibrutinib in Real-world Clinical Practice - a US Sub-study
Prospective, non-interventional study in patients with CSU where the treatment decision prior enrolment has been made to either escalate current sgH1-AHs treatment or escalate/switch current treatment to remibrutinib.
- Trial name
- REASSERT (NCT07358780)
- Where
- United States
- Volunteers
- 505 people
- Sponsor
- Novartis Pharmaceuticals
Fabry Disease
Efficacy and Safety of Enzyme Replacement Therapy in Patients With Fabry Disease
The goal of this observational study is to learn how enzyme replacement therapy works in patients with Fabry disease. The main question it aims to answer is: What medical problems do participants have? Participants already on…
- Trial name
- FAVORIT (NCT06880250)
- Where
- 23 sites in Russia
- Volunteers
- 100 people
- Sponsor
- NPO Petrovax
Caregivers, Community Health Workers
Intervention to Help Orient Men to Excel (IN-HOME) Phase II Study
The goal of the study is to examine the effect of outreach from IN-HOME-trained CHWs on changes in male informal caregiver knowledge/skills, positive attitudes, self-efficacy, and intentions about caregiving topics.
- Conditions
- Caregivers, Community Health Workers, Knowledge, Attitude
- Trial name
- IN-HOME (NCT07704060)
- Testing
- Intervention to Help Orient Men to Excel (IN-HOME), Supplying Useful Perimenopause Through Post-menopause Online Resources and Tools (SUPPORT)
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- KDH Research & Communication
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.