Clinical trials: Intervention Effectiveness
Temporomandibular Disorders (TMD), Bruxism
Behavioral Interventions for Controlling Oral Behaviors
Ecological momentary assessment (EMA) interventions via mobile devices can be implemented to monitor an individual's negative health behaviors in real-time, increase awareness, and assist patients in overting those behaviors.
- Conditions
- Temporomandibular Disorders (TMD), Bruxism, Masseter
- Trial name
- NCT07022795
- Testing
- Educational video combined with daily surveys, Educational video only
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Communication, Hypercholesterolemia
Influence of Intervention Methodologies on Patient Choice of Therapy
Few studies have explored how specific formats of effectiveness information effect on real patients' decisions. We only know little about what kind of format would be the optimal to help patients make well-informed real-life…
- Trial name
- IMPACT (NCT01414751)
- Testing
- Absolute risk reduction, Prolongation of life
- Volunteers
- 248 people
- Sponsor
- University of Southern Denmark
Dementia
A Home-based Training Program for Elderly Patients With Dementia
The illness course and symptoms of dementia is usually very long and characterized with behavioral, psychological and physical changes. Family caregivers' stresses change during the illness trajectory as well.
- Trial name
- NCT02667951
- Testing
- A home-based caregiver-training program
- Volunteers
- 129 people
- Sponsor
- Chang Gung Memorial Hospital
HIV Infections
Connecting Youth and Young Adults to Optimize ART Adherence: YouTHrive Efficacy Trial
YouTHrive (YT) is a two-arm randomized control trial (RCT) to test the efficacy of an adapted version of the Thrive With Me (TWM) intervention for youth living with HIV (YLWH).
- Trial name
- NCT03149757
- Testing
- YouTHrive, Information-only Control
- Where
- 7 sites in United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Caregiver Burden, Self Efficacy
An Online Ecoaching RCT Intervention for Carers: Enhancing Wellbeing and Resilience Through Self-Help Strategies
The goal of this three-armed, double-blind randomized controlled trial (RCT) is to compare the effectiveness of an online self-help eCoaching intervention designed for caregivers.
- Conditions
- Caregiver Burden, Self Efficacy, Quality of Life, Anxiety Depression
- Trial name
- NCT06604481
- Testing
- eCoaching for Caregivers of Older Adults, eCoaching (need specific) for Caregivers of Older Adults, Control Intervention for Caregivers of Older Adults
- Where
- Hong Kong
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Hip Fracture, Surgical Intervention
Efficacy and Safety of Intravenous Iron Sucrose in Patients With Hip Fracture to Prevent Perioperative Anemia
The purpose of this study is to evaluate the safety and efficacy of intravenous iron sucrose in patients with hip fracture and surgical intervention to prevent perioperative anemia.
- Trial name
- NCT01084122
- Testing
- Iron sucrose
- Where
- Spain
- Volunteers
- 360 people
- Sponsor
- Hospital Clinic of Barcelona
Cancer-related Problem/Condition, Cancer-related Fatigue
Engagement and Acceptability of the Untire mHealth App
The aim of this study will be to assess the engagement and acceptability of the Untire mHealth intervention for adults with cancer related fatigue. Acceptability will be assessed after 2, 4, 6 and 12 weeks of app use.
- Trial name
- NCT05891431
- Testing
- Untire mobile app
- Where
- 2 sites in United Kingdom
- Volunteers
- 34 people
- Sponsor
- University of Bath
Anemia, Iron Deficiency
Efficacy of Double Fortified Salt (DFS) to Improve Work Productivity in Women in India
The main objective of the present study is to assess the impact of double fortified salt containing iron and iodine on work performance (productivity) of women plantation workers in India.
- Trial name
- DFS (NCT01032005)
- Testing
- double fortified salt
- Where
- India
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- Micronutrient Initiative
Smoking, Pain
Pain and Smoking Study
This purpose of this study is to test the telephone delivery of a cognitive behavioral intervention (CBI), for smoking cessation among Veteran smokers with chronic pain
- Conditions
- Smoking, Pain, Smoking Cessation
- Trial name
- PASS (NCT02971137)
- Testing
- Smoking Cessation plus CBI, Smoking Cessation Standard
- Where
- 2 sites in United States
- Volunteers
- 371 people
- Sponsor
- VA Office of Research and Development
Thrombosis
Optical Coherence Tomography to Evaluate Ticagrelor and Clopidogrel
A number of 352 patients scheduled for elective percutaneous coronary intervention (PCI) with a native coronary stenosis suitable for DES implantation and OCT imaging are openly randomized 1:1 to either BRILINTA™ (ticagrelor) or…
- Trial name
- NCT02140801
- Testing
- Ticagrelor, Clopidogrel
- Where
- China
- Volunteers
- 352 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Breastfeeding Self-Efficacy, Exclusive Breastfeeding
Breastfeeding Simulation in Prenatal Education
Breastfeeding education should be initiated during pregnancy. Simulation is an effective educational technique that has been little explored in the context of prenatal education.
- Trial name
- NCT06701227
- Testing
- In Situ Simulation
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
Eating Behavior
Healthy Online Parental Education Project to Increase Fruit and Vegetable Intake and Active Playtime Among Toddlers
The research proposal will be an 8-week randomized control trial (RCT) to examine the efficacy of an eHealth intervention, namely Healthy Parental Online Education (HOPE), on fruit and vegetable intake and active playtime among…
- Trial name
- HOPE (NCT05085041)
- Testing
- Multi-Component eHealth Intervention, namely Healthy Online Parental Education (HOPE)
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Employee Well-being, Work-related Outcomes
Effectiveness of a Multi-Modal Workplace Rest Cabin on Worker Well-Being
This study examines whether access to a rest cabin in the workplace supports employee well-being. Employees of a Canadian insurance company are randomly assigned to one of two groups: immediate access to the rest cabin or a…
- Trial name
- RECHARJME-RCT (NCT07322354)
- Testing
- Recharjme Multi-Modal Rest Cabin
- Where
- 4 sites in Canada
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Laval University
Diabetes Mellitus
Effects of a Patient Portal Intervention to Address Diabetes Care Gaps
The purpose of this study is to evaluate the effect of a novel patient portal intervention on the number of patients with diabetes care gaps (e.g., no diabetes eye exam i the last 12 months).
- Trial name
- NCT04894903
- Testing
- Diabetes Care Gaps Patient Portal Intervention
- Where
- United States
- Volunteers
- 440 people
- Sponsor
- Vanderbilt University Medical Center
No Specific Conditions
Acceptance and Commitment Therapy for Informal Caregivers of People With Dementia
Dementia has a major impact on people with dementia and their family. Informal caregivers of people with dementia are at higher risk of developing depressive symptoms compared to informal caregivers of people with other chronic…
- Trial name
- ACT-IC (NCT05064969)
- Testing
- Blended intervention based in acceptance and commitment therapy
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Psoriatic Arthritis
Psoriatic Oligoarthritis Intervention With Symptomatic thErapy
POISE is a two arm interventional trial nested within a cohort (Trials Within Cohorts or TWiCs design). This tests less aggressive early therapy in patients newly diagnosed with low impact oligoarticular PsA.
- Trial name
- POISE (NCT03797872)
- Testing
- Methotrexate, Sulfasalazine, Leflunomide
- Where
- United Kingdom
- Volunteers
- 1 people
- Sponsor
- University of Oxford
Liver Fibrosis
Effect of Imatinib in Advance Liver Fibrosis Patients
When a recurrent, long-term injury and inflammation of the liver causes an excessive accumulation of damaged tissue, a dangerous condition called liver fibrosis develops. Most chronic liver diseases eventually lead to fibrosis.
- Trial name
- NCT05224128
- Testing
- Imatinib 200mg
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Research Institute for Gastroenterology and Liver Diseases (RIGLD)
Coronary Artery Disease
Evaluation of Effectiveness and Safety of Xience Skypoint Stents in Routine Clinical Practice
The objective of this study is to evaluate the effectiveness and safety of XIENCE Skypoint stents in comparison to other drug-eluting stents (DES) in real-world practice.
- Trial name
- IRIS Skypoint (NCT05981911)
- Testing
- XIENCE Skypoint™ stent
- Where
- South Korea
- Volunteers
- 2,000 people
- Sponsor
- Seung-Jung Park
Mindful Leadership
Exploring the Efficacy of Mindful Leadership Interventions in Public Administration
The goal of this clinical trial is to evaluate the effectiveness of a mindful leadership intervention compared to a management skills training program in executive staff working in public administration.
- Trial name
- NCT07132931
- Testing
- Mindful Leadership Intervention, Management Skills Training
- Where
- Spain
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Pulmonary Disease, Chronic Obstructive
Vahelva Respimat Regulatory Post-marketing Surveillance in Korean Patients With Chronic Obstructive Pulmonary Disease
To monitor the safety profile and effectiveness of Vahelva Respimat in Korean patients with COPD in a routine clinical practice setting
- Trial name
- NCT02864407
- Testing
- Vahelva® Respimat® (Tiotropium + Olodaterol fixed dose combination)
- Where
- South Korea
- Volunteers
- 3,223 people
- Sponsor
- Boehringer Ingelheim
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