Clinical trials: Intervention Effectiveness
HIV Infections
Effectiveness of Communication Technology in Disseminating HIV Prevention Training to Non-governmental Organizations
This study will compare the effectiveness of face-to-face training versus Web-based training seminars in disseminating HIV prevention interventions to nongovernmental organizations in Eastern Europe and Central Asia.
- Trial name
- NCT00698529
- Testing
- Face-to-face training, Distance training, Popular Opinion Leader (POL)
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Peripheral Artery Disease
AcoArt Ⅱ/ BTK China: Drug-eluting Balloon for Below-The-Knee Angioplasty Evaluation in China
The purpose of this study is to determine whether DEB is more effective than common PTA balloon using under in long-term vessel patency and inhibiting restenosis in the infrapopliteal artery.
- Trial name
- NCT02137577
- Testing
- DEB catheter, common PTA balloon catheter
- Where
- 11 sites in China
- Volunteers
- 120 people
- Sponsor
- Acotec Scientific Co., Ltd
Retinal Vein Occlusion, Age Related Macular Degeneration
Efficacy and Safety of Lucentis® (Ranibizumab Intravitreal Injections) in Chilean Patients With Diabetic Macular Edema.
Ranibizumab is a humanized anti-vascular endothelial growth factor (VEGF) monoclonal antibody fragment approved in Chile by the Instituto de Salud Pública for the treatment of diabetic macular edema (DME), retinal vein occlusion…
- Trial name
- NCT02140411
- Testing
- Ranibizumab Intravitreal injections
- Where
- Chile
- Volunteers
- 21 people
- Sponsor
- Novartis Pharmaceuticals
Computed Tomography-guided Nasotracheal Intubation, The Space Where the Tube Will be Passed in the Internal Nasal Valve Region
Computed Tomography-Guided Nasotracheal Intubation Procedure
Background: Nasotracheal intubation can lead to severe complications like epistaxis with excessive bleeding. The advancement difficulty of the tube faced during nasal intubation is one of the fundamental causes of this condition.
- Trial name
- NCT05525754
- Testing
- computed tomography-guided nasotracheal intubation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
No Disease
Web-based Acceptance and Commitment Therapy (ACT) Intervention for University Students
University students frequently experience psychological distress, reduced wellbeing, and academic challenges associated with the transition to higher education.
- Trial name
- NCT07753837
- Testing
- Web-based ACT intervention for University Students
- Where
- Pakistan
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- National University of Modern Languages
Fasciitis
Effects of Different Foot Structures on Plantar Fasciitis and Therapeutic Footwear Intervention
Excessive repetitive loading concentrating upon plantar fascia is considered as the most influential factor in plantar fasciitis development. Abnormal foot structure may lead to high risk of plantar fasciitis.
- Trial name
- NCT01363375
- Testing
- Foot orthosis, footwear
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Dental Anxiety of Hearing Impairment
Effectiveness of Virtual Reality vs Show-Do Technique on Dental Anxiety in Children With Hearing Impairment
This randomized controlled clinical trial aims to compare the effectiveness of virtual reality (VR) eyewear used as a distraction method in combination with the Show-Do (SD) technique versus the traditional Show-Do technique…
- Trial name
- NCT07245030
- Testing
- virtual reality distraction, show-do technique
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- October University for Modern Sciences and Arts
Diabetes Mellitus, Type 2
Effectiveness of App-based Positive Psychological Intervention on Patients Newly Diagnosed With Type 2 Diabetes
The aim of this experimental study is to explore the effectiveness of app-based positive psychology intervention (PPI) on patients newly diagnosed with type 2 diabetes (T2DM).
- Trial name
- NCT05174975
- Testing
- App-based Positive Psychological Intervention
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Breast Cancer, Sleep Hygiene
Feasibility and Effectiveness of a Sleep Hygiene Education Program for Sleep Issues in Breast Cancer Survivors
The proposed research will assess the feasibility and preliminary effectiveness of a Sleep Hygiene Program for Breast Cancer Survivors.
- Trial name
- NCT04232319
- Testing
- Sleep Hygiene Training
- Where
- United States
- Sponsor
- University of Toledo Health Science Campus
Peripheral Artery Disease, Peripheral Vascular Disease
Investigational Device Exemption Study to Determine the Safety and Efficacy of the Astron and Pulsar Stents
The objective of this study is to separately demonstrate the safety and efficacy of BIOTRONIK's Astron and Pulsar stents. The Pulsar stent will be used for the treatment of femoro-popliteal lesions, located in the native…
- Trial name
- BIOFLEX-I (NCT01319812)
- Testing
- Astron Stents, Pulsar Stents
- Where
- 35 sites in United States, Canada
- Volunteers
- 463 people
- Sponsor
- Biotronik, Inc.
Depression, Anxiety
Efficacy of COMET on Prolific Participants
In this study, the investigators will test the effectiveness of a digital, single-session mental health intervention. There will be two conditions: the COMET intervention and the control group.
- Conditions
- Depression, Anxiety, Emotion Regulation
- Trial name
- COMET-Prol (NCT05379881)
- Testing
- Common Elements Toolbox (COMET)
- Where
- United States
- Volunteers
- 829 people, healthy volunteers welcome
- Sponsor
- Indiana University
Healthy Men Age 50 Who Are Considering PSA Screening
Decision Support Interventions (DESI) for Prostate Cancer Screening - Study 1
In this study we will compare 3 strategies for systematic delivery of prostate cancer screening decision support interventions (DESI) to usual care and examine their impact on screening decisions and subsequent healthcare…
- Trial name
- NCT01241656
- Testing
- DESI for home viewing, DESI for viewing at Shared Medical Appointment, Option of SMA and DESI or DESI only
- Where
- 2 sites in United States
- Volunteers
- 2,521 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Airway Management
Comparison of I-gel LMA, Classical LMA With a New Supraglottic Airway the Baska Mask® in Urological Surgery
The most used airway management strategies are different types of supraglottic airway devices (SAD) for transurethral resection of bladder and ureteroscopy in urological surgery .
- Trial name
- BCIM (NCT03002857)
- Testing
- LMA-C, Baska Mask, I-gel
- Volunteers
- 150 people
- Sponsor
- Adiyaman University Research Hospital
Maternal Health Service
Checklist Based Box System Interventions
Maternal mortality is still high in Ethiopia. Antenatal care (ANC), use of skilled delivery attendants and postnatal care (PNC) services are key maternal health care services that can significantly reduce maternal mortality.
- Trial name
- CBBSI (NCT03891030)
- Testing
- Checklist Based Box system intervention
- Where
- Ethiopia
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Jimma University
STEMI With Multivessel Coronary Disease
Safety and Efficacy of Bivalirudin During Short-term Intervention of Non-infarction Related Artery After PPCI of STEMI
This is a randomized, open label, cohort study, in which a total of 100 patients will be enrolled and randomly assigned to receive bivalirudin or heparin in a 1:1 ratio during short-term intervention of non-infarction related…
- Trial name
- NCT04475835
- Testing
- Bivalirudin, Heparin
- Where
- China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Wound Care, Pain Intensity
Pain Medicine for Wound Care Procedures
This is a randomized double-blind study to determine if the administration of a small-dose of ketamine (an anesthetic)added to morphine (an opioid) contributes to reducing pain intensity during open wound care procedure (WCP)in…
- Conditions
- Wound Care, Pain Intensity, Hyperalgesia, Nausea
- Trial name
- NCT00701909
- Testing
- Morphine plus Ketamine
- Where
- 2 sites in United States, Puerto Rico
- Volunteers
- 12 people
- Sponsor
- University of California, San Francisco
Pain, Other Surgical Procedures
Influence of Genotype of CYP2C9 on Clinical Efficacy and Pharmacokinetics of Piroxicam After Lower Third Molar Surgery
Pharmacogenetics is an area of Pharmacology that studies the contribution of genetic factors to individual responses to drugs. This branch of science involves the variability in pharmacodynamics and pharmacokinetics through the…
- Conditions
- Pain, Other Surgical Procedures, Impacted Third Molar Tooth, Cytochrome P450 CYP2C9 Enzyme Deficiency
- Trial name
- NCT02450487
- Testing
- Piroxicam
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Coronary Heart Disease, Low Protein Intake
Protein Intake in Patients With Coronary Heart Disease
Sarcopenia is a skeletal muscle disease, characterised by low muscle strength and muscle mass, and associated with higher medical care costs, shorter life expectancy and physical dependence.
- Conditions
- Coronary Heart Disease, Low Protein Intake, Sarcopenia
- Trial name
- NCT04999358
- Testing
- Protein education, Standard education
- Where
- United Kingdom
- Volunteers
- 35 people
- Sponsor
- Northumbria University
ADHD
Efficacy of an Occupational Intervention for Improving Quality of Work Life in Adults Living With ADHD
An adaptation of the Minds@Work intervention to improve quality of life at work for adults living with attention deficit disorder with/without hyperactivity (ADHD), following a group format.
- Trial name
- NCT06774378
- Testing
- Minds@Work-ADHD-Quality of Life, Minimal contact
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Université du Québec a Montréal
Intimate Partner Violence (IPV), Interpersonal Psychotherapy
Effectiveness of Interpersonal Relationship Psychotherapy Intervention for Female Victims of Intimate Partner Violence
This interventional study aims to examine the impact of the Interpersonal Relationship Psychotherapy-Based Intervention Program on the psychosocial well-being of female victims of intimate partner violence.
- Conditions
- Intimate Partner Violence (IPV), Interpersonal Psychotherapy, Interpersonal Relations
- Trial name
- NCT06687278
- Testing
- Interpersonal Relationship Psychotherapy-Based Intervention Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
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