Clinical trials: Intervention Effectiveness
Depression
Effectiveness of Story-Centred Care Intervention Program in Older Persons Living in Long-term Care Facilities
The study aim is to evaluate the effectiveness of Story-Centred Care Intervention Program on reducing depressive symptoms, improving cognitive function, HRV, Blood pressure and quality of life in older adults living in a…
- Trial name
- NCT02965937
- Testing
- Story-centred care intervention program, Health consultation control condition
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Shoulder Pain
Effectiveness of Action Observation and Motor Imagery Intervention Plus Exercise for Chronic Painful Shoulder in Primary Care
Objective: to evaluate the effectiveness of an action observation program (OA) and motor imagery (MI) -integrated into routine physiotherapy practice- to reduce disability associated with chronic shoulder pain in primary care…
- Trial name
- OPTIMIST (NCT04118439)
- Testing
- Motor Imaginery and Action Observation
- Volunteers
- 100 people
- Sponsor
- Universidad Autonoma de Madrid
Musculoskeletal Injury
Psychologically-Based Physical Therapy Treatment for Deployed U.S. Sailors and Marines With Musculoskeletal Injuries
The main objective of this pilot project is to demonstrate the effectiveness of a psychologically-based physical therapy (PBPT) intervention for the prevention of disability in Active Duty Service Members who sustained a…
- Trial name
- NCT02472067
- Testing
- Psychologically - Based Physical Therapy
- Volunteers
- 175 people
- Sponsor
- NYU Langone Health
Older Adults
Remote Interactive Intervention for Loneliness
Background: During the COVID-19 pandemic, governments around the world adopted the practice of physical distancing, which increased the loneliness experienced by seniors and indirectly affected their quality of life and social…
- Trial name
- NCT05459103
- Testing
- Bidirectional remote interaction intervention, Unidirectional remote interaction intervention
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yang Shang-Yu
Mental Health Issue
Determining the Effectiveness of Working Out Dads to Reduce Mental Health Difficulties in Fathers of Young Children
This is an individually randomised trial, where Working Out Dads (WOD) will be delivered as a group intervention. Participants will be randomised to one of two groups: either WOD or usual care.The trial aims to test the…
- Trial name
- WOD (NCT04813042)
- Testing
- Working Out Dads, Usual care
- Where
- Australia
- Volunteers
- 293 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Breast Cancer
A Non-interventional Study for Women With HR-positive, HER2-negative Locally Advanced or Metastatic Breast Cancer to Evaluate the Real-world Effectiveness of Treatment Algorithms Beginning With Ribociclib + AI/FUL, or With Endocrine Therapy or Chemotherapy as First Line Treatment
This is a non-interventional observational study conducted in Germany to evaluate the real-world effectiveness, tolerability, safety, and quality of life in patients with locally advanced/metastatic HR+/HER2- breast cancer…
- Trial name
- RIBANNA (NCT06311383)
- Testing
- First-line Ribociclib + endocrine therapy, First-line endocrine therapy, First-line chemtherapy
- Where
- 265 sites in Germany
- Volunteers
- 2,610 people
- Sponsor
- Novartis Pharmaceuticals
Driving Risk Factors Among Adolescents With ADHD
The Effectiveness of Cognitive-Functional Intervention to Reduce Driving Risk Factors of Adolescents With ADHD
Background: Attention deficit hyperactivity disorder (ADHD) is associated with a high risk for driving accidents. Adolescents with ADHD are 1.2 to 4 times more prone to be involved in car accidents.
- Trial name
- NCT05832957
- Testing
- Drive fun, educational intervention, No intervention
- Where
- Israel
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Hospital-Acquired Pneumonia
Efficacy and Safety of Ceftazidime-Avibactam (CAZ-AVI) in Chinese Participants With HAP (Including VAP)
This is a prospective, single arm, open-label, multi-center clinical study evaluating the effectiveness and safety of CAZ-AVI in participants with HAP (including VAP), who have initiated treatment with CAZ-AVI in an inpatient…
- Trial name
- NCT04774094
- Testing
- Zavicefta, Ceftazidime-Avibactam
- Where
- 56 sites in China
- Volunteers
- 235 people
- Sponsor
- Pfizer
Carcinoma, Non-Small-Cell Lung
Symbiotic-Lung-10: A Study to Learn About PF-08634404 Alone or in Combination in Early-stage or Locally Advanced NSCLC
This study is being done to learn more about a new medicine called PF-08634404. The study team wants to understand how well it works when given alone or with chemotherapy.
- Conditions
- Carcinoma, Non-Small-Cell Lung, Lung Cancer (NSCLC), Lung Neoplasms
- Trial name
- NCT07489066
- Testing
- PF-08634404, Chemotherapy Regimen 1, Chemotherapy Regimen 2
- Where
- 37 sites in United States, Australia and 9 more
- Volunteers
- 120 people
- Sponsor
- Pfizer
Sexual Assault
Using VR to Assess the Efficacy of a Motivational Interviewing Intervention to Increase Bystander Behaviors
With the present project, we will a evaluate a new, motivational interviewing (MI) intervention for increasing bystander behaviors to prevent sexual violence.
- Trial name
- VR (NCT04160702)
- Testing
- Motivate-The-Bystander (MTB)
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Stroke, Self Efficacy
Visual Arts-based Intervention for Community-dwelling Stroke Survivors
Stroke is the major cause of disability worldwide and leads to psychosocial issues for community-dwelling stroke survivors in their recovery journey.
- Conditions
- Stroke, Self Efficacy, Psychosocial Problem
- Trial name
- NCT06395857
- Testing
- Visual arts-based intervention
- Where
- Macau
- Volunteers
- 32 people
- Sponsor
- The Nethersole School of Nursing
Coronary Artery Disease
Technology-Enhanced Continuous Nursing System (TECNS) for Post-CABG Recovery
This is a prospective, randomized controlled trial to evaluate the effectiveness of a Technology-Enhanced Continuous Nursing System (TECNS) compared to routine care for patients after coronary artery bypass grafting (CABG).
- Trial name
- NCT07117331
- Testing
- Technology-Enhanced Continuous Nursing System, Routine Postoperative Care
- Where
- China
- Volunteers
- 358 people
- Sponsor
- The First Hospital of Hebei Medical University
Menopause, Perimenopausal Disorder
Effectiveness of Assessment and Educational Intervention on Motor Control of the Pelvic Floor Muscle in Women
The goal of the present study is to evaluate the short and long term effectiveness of a tailored assessment and educational intervention on motor control of the pelvic floor muscle in menopausal and non-menopausal women.
- Trial name
- MENO_edu (NCT03220672)
- Testing
- Tailored assessment and educational
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Malaga
Coronary Artery Disease
IRIS-Synergy Cohort in the IRIS-DES Registry
The purpose of this study is to evaluate the relative effectiveness and safety of Synergy stent compared to other drug eluting stents.
- Trial name
- IRIS Synergy (NCT02720419)
- Where
- 28 sites in South Korea
- Volunteers
- 3,000 people
- Sponsor
- Jung-min Ahn
Methicillin-Resistant Staphylococcus Aureus, Recurrence
Patient-Centered Comparative Effectiveness Research (CER) Study of Home-based Interventions to Prevent CA-MRSA Infection Recurrence
The overall goal of the project is to develop and evaluate a home-based intervention to prevent re-infection and transmission of Community-Acquired Methicillin-resistant Staphylococcus aureus (CA-MRSA) in patients presenting to…
- Conditions
- Methicillin-Resistant Staphylococcus Aureus, Recurrence, Staphylococcal Skin Infections, Antibiotic Resistance
- Trial name
- CAMP-2 (NCT02566928)
- Testing
- 2% mupirocin ointment, Chlorhexidine wash, Hygiene protocol
- Where
- 6 sites in United States
- Volunteers
- 278 people
- Sponsor
- Clinical Directors Network
Hypertension, Primary Care
Fixed-Dose Combinations Pragmatic Randomized Implementation Trial for Blood Pressure Control
The proposed study is an effectiveness-implementation hybrid type II trial designed to evaluate the impact of provider- and patient-directed interventions on FDC use.
- Trial name
- NCT07228065
- Testing
- Provider nudge, Patient nudge, Pharmacist Virtual Visit
- Where
- United States
- Volunteers
- 720 people
- Sponsor
- Brigham and Women's Hospital
Locally Advanced Breast Cancer, Metastatic Breast Cancer
A Study to Evaluate the Effectiveness and Safety of Inavolisib in Participants With Endocrine-resistant, PIK3CA-mutated, Hormone Receptor-positive, HER2-negative Locally Advanced or Metastatic Breast Cancer
The main purpose of this study is to evaluate the effectiveness of inavolisib based regimen in participants with endocrine-resistant, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha gene (PIK3CA)-mutated…
- Trial name
- reaINAVO (NCT07347600)
- Testing
- Inavolisib, Palbociclib, Fulvestrant
- Where
- 32 sites in China
- Volunteers
- 500 people
- Sponsor
- Hoffmann-La Roche
Acute Myocardial Infarction (AMI), Percutaneous Coronary Intervention (PCI)
Efficacy and Safety of Shexiang Baoxin Pill(MUSKARDIA) in the Treatment of Acute Myocardial Infarction
This study aims to evaluate the value of Shexiang Baoxin Pill (MUSKARDIA) in patients with acute myocardial infarction (AMI) through a prospective, multicenter, pragmatic randomized controlled real-world study.
- Trial name
- MUST Ⅱ (NCT07153744)
- Testing
- Aspirin, Shexiang Baoxin Pill
- Where
- China
- Volunteers
- 9,588 people
- Sponsor
- Shanghai Hutchison Pharmaceuticals Limited
Hypertension, Hypertension (Without Type 2 Diabetes Mellitus)
Effectiveness of Phone Call and Video-based Interventions to Improve Adherence to Medications in Hypertensive Patients
The goal of this clinical trial is to find out if phone call and video-based interventions that seek to educate people with uncontrolled high blood pressure and also remind them to take their medicines will improve adherence to…
- Trial name
- NCT06927271
- Testing
- phone call based intervention, Video based intervention, Usual Care
- Where
- Ghana
- Volunteers
- 1,400 people
- Sponsor
- University of Ghana
Chronic Kidney Disease 5D, Secondary Hyperparathyroidism
A Observational Study to Evaluate the Efficacy and Safety of Pacitol Inj.
The purpose of this study is to evaluate the efficacy and safety of pacitol Inj.(paricalcitol) for secondary hyperparathyroidism with stage 5D chronic kidney disease (CKD 5D) receiving hemodialysis
- Trial name
- NCT06126016
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Boryung Pharmaceutical Co., Ltd
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