Clinical trials: Intervention Effectiveness
Cancer Pain
Study to Evaluate Effectiveness and Tolerability of OROS Hydromorphone for Cancer Pain Treatment in Korean Patients
The purpose of this study is to evaluate the effectiveness and tolerability of Once-Daily OROS ("Osmotic Release Oral System" [a controlled release oral medication delivery system in the form of a tablet]) hydromorphone for…
- Trial name
- NCT01621100
- Testing
- OROS hydromorphone
- Where
- 6 sites in South Korea
- Volunteers
- 106 people
- Sponsor
- Janssen Korea, Ltd., Korea
Bipolar Disorder
Effectiveness of Family-Focused Treatment Plus Pharmacotherapy for Bipolar Disorder in Adolescents
This study will evaluate the effectiveness of family-focused treatment (FFT) plus pharmacotherapy in treating adolescents with bipolar disorder.
- Trial name
- NCT00332098
- Testing
- Family-Focused Treatment Plus Pharmacotherapy, Enhanced Care Plus Pharmacotherapy
- Where
- 3 sites in United States
- Volunteers
- 145 people
- Sponsor
- University of California, Los Angeles
Diet, Mediterranean, Health Behavior
Feeding America's Bravest: Mediterranean Diet-Based Interventions to Change Firefighters' Eating Habits
The purpose of this study is to modify the food culture of the fire service by motivating firefighters and their families to incorporate Mediterranean diet principles at work and home through behavior change strategies that…
- Conditions
- Diet, Mediterranean, Health Behavior, Program Sustainability, Program Effectiveness
- Trial name
- NCT02941757
- Testing
- Mediterranean diet Intervention
- Where
- United States
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Nonsquamous Non-small Cell Lung Cancer
Safety and Efficacy Study of Pemetrexed + Platinum Chemotherapy + Pembrolizumab (MK-3475) With or Without Lenvatinib (MK-7902/E7080) as First-line Intervention in Adults With Metastatic Nonsquamous Non-small Cell Lung Cancer (MK-7902-006/E7080-G000-315/LEAP-006)
The purpose of this study is to assess the safety and efficacy of pemetrexed + platinum chemotherapy + pembrolizumab (MK-3475) with or without lenvatinib (MK-7902/E7080) as first-line intervention in adults with metastatic…
- Trial name
- NCT03829319
- Testing
- Pembrolizumab, Carboplatin, Cisplatin
- Where
- 158 sites in United States, Argentina and 15 more
- Volunteers
- 761 people
- Sponsor
- Merck Sharp & Dohme LLC
Autism Spectrum Disorder
Cognitive Support Technology for Postsecondary Students With Autism Spectrum Disorder
This study will fill important knowledge gaps in the availability of best practices that use innovative methods to integrate the cognitive and vocational needs of students with Autism Spectrum Disorder (ASD) who will be…
- Trial name
- NCT04980963
- Testing
- Cognitive Support Technology (CST)
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kent State University
Insomnia
Implementation of CBT-I in Cancer Clinics
Insomnia affects 30-60% of cancer patients, thus making it one of the most common disturbances in this population. When untreated, which is the rule rather than the exception, insomnia often becomes chronic.
- Trial name
- NCT04817163
- Testing
- Web-based cognitive-behavioral therapy for insomnia (CBT-I), Professionally-administered booster face-to-face CBT-I sessions
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- CHU de Quebec-Universite Laval
Developmental Delay
Development and Effectiveness of Home-based Programs for Preschool Children With Developmental Delay
Early intervention refers to the provision of early detection, early diagnosis, and early intervention for infants and young children with special needs.
- Trial name
- NCT02115334
- Testing
- professional therapists delivering the PHPA, parents executing the PHPA, health education
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Smoking
Medical Student INtervention to Promote Effective Nicotine Dependence and Tobacco HEalthcare
Background: Smoking counselling during hospitalisation with post-discharge follow-up increases quitting. However, provision of cessation care for hospitalised patients is suboptimal.
- Trial name
- MIND-THE-GAP (NCT02601599)
- Testing
- Motivational interviewing
- Where
- Ireland
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Royal College of Surgeons, Ireland
Healthy Eating
In-person and Online Healthy Eating Promotion Through Self-regulation (HEP-S)
Obesity has more than doubled worldwide since 1980. The challenge with obesity, as with many other modern diseases, is that the solution may not rely on the medical side of the chain but rather on the individual via modifiable…
- Trial name
- HEP-S (NCT04099498)
- Testing
- Online Program: Healthy Eating Promotion with Self-regulation, Enhanced Online Program: Healthy Eating Promotion with Self-regulation
- Where
- Portugal
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Minho
Splenectomized Patients, Splenectomy
Evaluation of the Effectiveness of an Educational Intervention in Splenectomized Patients
The absence or dysfunction of the spleen is associated with a substantially increased risk of invasive infections that may rapidly progress to fulminant sepsis, including overwhelming post-splenectomy infection (OPSI), a medical…
- Conditions
- Splenectomized Patients, Splenectomy, Splenectomy; Status, Asplenia
- Trial name
- SPLE-VAC (NCT07354893)
- Testing
- Educational intervention for asplenic patients
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Quality of Life, Self Efficacy
Oral Health Education Interventions Among Seniors
The study aims to assess the efficacy of an oral health education group based activity versus an individual based oral health education activity in terms of changes in oral health related quality of life (OHRQoL), self-efficacy…
- Conditions
- Quality of Life, Self Efficacy, Knowledge
- Trial name
- NCT03301714
- Testing
- Oral Health Education
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Temple University
Non-specific Chronic Low Back Pain, Central Sensitization
Exercise Interventions for Overweight Men With Chronic Low Back Pain
This randomized controlled trial aims to compare the effectiveness of motor control exercise, aerobic walking exercise, and muscle strengthening exercise in overweight male adults with non-specific chronic low back pain and…
- Trial name
- MAMS-CLBP (NCT07688564)
- Testing
- Motor Control Exercise, Aerobic Walking Exercise, Muscle Strengthening Exercise
- Where
- Saudi Arabia
- Volunteers
- 156 people
- Sponsor
- Universiti Sains Malaysia
Myocardial Infarction
Studying the Effectiveness of Early Invasive Treatment in Elderly Patients With High-risk Non-ST-segment Elevation Acute Coronary Syndrome.
The goal of this is observational study is to compare about MACE events and predisposing factors related to MACE events in elderly patients with high-risk non-ST acute coronary syndromes receiving early versus late invasive…
- Trial name
- NCT06486233
- Where
- Vietnam
- Volunteers
- 385 people
- Sponsor
- Gia Dinh People Hospital
Depression
Cost- Effectiveness and Quality of Life Assessment in Major Depression Disorder
To evaluate the effectiveness of one algorithm for Major Depression Disorder (MDD) using medications available in the Brazilian Public Healthcare System (SUS), and assessment of the quality of life of these patients.
- Trial name
- NCT02901249
- Testing
- sertraline, Nortriptyline, Lithium
- Volunteers
- 68 people
- Sponsor
- Federal University of Rio Grande do Sul
Stunting in Under-2 Children
Evaluating Bundling of Nutrition-specific Interventions
Background: 1. Burden: The prevalence of stunting among the under-five children in Bangladesh was >55% in 1997, which reduced to 41.9% in 2011.
- Trial name
- NCT02768181
- Testing
- Nutrition-specific Behaviour change communication (BCC), Nutrient supplement to pregnant women (PNS), Nutrienr supplement to children 6m to 2 years
- Where
- Bangladesh
- Volunteers
- 2,880 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Pregnancy
Educational Program on Exercise During Pregnancy
This study aims to evaluate whether a short educational session about safe therapeutic exercise during pregnancy can improve knowledge, confidence, and physical activity levels in pregnant women.
- Trial name
- EDUPREG (NCT07486999)
- Testing
- Educational Session on Therapeutic Exercise During Pregnancy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Oviedo
Insomnia, Behavioral Intervention
The Effectiveness of an Educational Intervention Based on Self-help for Sleep Hygiene Promotion on Patients With Insomnia
This plan will be implemented on the staff of the Qazvin University of Medical Sciences. The Insomnia Severity Index questionnaire will be used to screen for insomnia and low sleep health.
- Trial name
- NCT03605732
- Testing
- self help sleep hygiene intervention application, patients education
- Where
- Iran
- Volunteers
- 312 people
- Sponsor
- Qazvin University Of Medical Sciences
Non-Hodgkin Lymphoma, B-cell, Acute Lymphoblastic Leukemia ALL
An Extension Study to Evaluate the Safety and Efficacy of an Anti-CD19 CAR-T Product in Patients with B-cell Lymphoproliferative Disorders
This follow-up study is designed to evaluate the long-term safety and effectiveness of a treatment called anti-CD19 CAR-T cell therapy in adults with certain B-cell blood cancers.
- Trial name
- NCT06721598
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- National Research Center for Hematology, Russia
Breast Cancer Female, Side Effects
Rehabilitation Through Hippotherapy for the Management of Women After Primary Treatment of Breast Cancer
Breast cancer is the most common women's cancer and the third leading cause of death. Advances in prevention, detection and primary treatment have improved overall survival leading to its growing acceptance as a long-term…
- Conditions
- Breast Cancer Female, Side Effects, Psychological Distress, Physical Disability
- Trial name
- HippoBreastCa (NCT04350398)
- Testing
- Hippotherapy, Conventional therapy
- Where
- France
- Volunteers
- 83 people
- Sponsor
- Alliance Equiphoria
Primary Osteoporosis
The Study of Chinese Medicine for the Treatment of Primary Osteoporosis
The purpose of this study is to evaluate the efficacy and possible mechanism of traditional Chinese medicine in the treatment of primary osteoporosis (Kidney Yang Deficiency Syndrome).It is a randomized, placebo-controlled trial.
- Trial name
- NCT05370898
- Testing
- Caltrate D, Chinese medicine prescription
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Wangjing Hospital, China Academy of Chinese Medical Sciences
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