Clinical trials: Intervention Effectiveness
Mental Health
Supporting Refugee and Immigrant Youth's Mental Health
The purpose of this study is to examine the effectiveness of STRONG on the mental health of refugee and immigrant students using a group randomized waitlist control design (e.g., randomization by school/group).
- Trial name
- NCT05208359
- Testing
- Supporting Transition Resilience Of Newcomer Groups (STRONG)
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Loyola University Chicago
Lyme Disease
A School-Based Intervention to Reduce Lyme Disease
Our overall purpose of this study is evaluate whether a short in-class Lyme Disease education program based on social learning theory and the Health Belief Model can impact a child's knowledge, attitude, and preventive behavior.
- Trial name
- NCT00594997
- Testing
- Education, Control (pre and post surveys)
- Volunteers
- 3,570 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Substance Use, Sexual Risk
Examining Community-based Effectiveness of a Substance Use and HIV Risk Reduction Intervention for Young Men of Color
This study will conduct an effectiveness trial of the 4-session evidence-based YMHP intervention for young men who have sex with men (YMSM) of color ages 15-29 at two CBOs in New York City, compared to usual care.
- Trial name
- YMHP-CBO (NCT03488914)
- Testing
- YMHP Intervention, Enhanced Treatment as Usual
- Where
- 2 sites in United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Hunter College of City University of New York
COVID-19
Treatment of COVID-19 Patients With Anti-interleukin Drugs
The purpose of this study is to test the safety and effectiveness of individually or simultaneously blocking IL-6 and IL-1 versus standard of care on blood oxygenation and systemic cytokine release syndrome in patients with…
- Trial name
- COV-AID (NCT04330638)
- Testing
- Usual Care, Anakinra, Siltuximab
- Where
- 15 sites in Belgium
- Volunteers
- 342 people
- Sponsor
- University Hospital, Ghent
Atrial Fibrillation
EdoxabaN or Warfarin Therapy In Device Procedures in Patients With Non-Valvular Atrial Fibrillation
This is a prospective randomized comparative evaluation of Edoxaban and Warfarin for safety and efficacy in perioperative use in patients with non-valvular atrial fibrillation (AF) undergoing clinically indicated implantation or…
- Trial name
- ENTICED-AF (NCT02561897)
- Testing
- Edoxaban, Warfarin
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Electrophysiology Research Foundation
Multiple Sclerosis
Teleconference Fatigue Management for People With Multiple Sclerosis
Approximately 60% of individuals with multiple sclerosis (MS) describe fatigue as their most disabling symptom. Energy conservation education involves teaching people with MS different strategies to manage fatigue and reduce its…
- Trial name
- NCT00591721
- Testing
- Energy conservation education
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- University of Illinois Chicago
Pneumonia, Ventilator Associated
Pilot Study of Lateral Rotation Interventions for Efficacy and Safety in ICU Care
Intensive care unit (ICU) patients on respirators are at high risk for preventable pulmonary complications (PPC). Turning these patients from side to side may reduce PPC, but carries the burden of decreases in blood pressure and…
- Trial name
- NCT00542321
- Testing
- Manual turn, kinetic therapy bed
- Volunteers
- 16 people
- Sponsor
- The University of Texas Health Science Center, Houston
Childhood Obesity
Motivational Interviewing for Weight Loss
The investigators studied the effect of motivational interviewing (MI) on self-efficacy, health behaviors, and health outcomes in overweight children and adolescents (ages ranging from 10 to 18 years).
- Trial name
- NCT01246349
- Testing
- Motivational Interviewing (Treatment Group), Social Skills Training (Control Group)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- The Hospital for Sick Children
Communicable Diseases, Prevention
SAFE Workplace Intervention for People With IDD
The purpose of this study is to examine the feasibility and efficacy of a systematic training approach targeting behaviors to increase safety and prevention of airborne diseases such as COVID-19 in the workplace for individuals…
- Conditions
- Communicable Diseases, Prevention, Workplace Intervention
- Trial name
- NCT06112249
- Testing
- SAFE Employment Training
- Where
- 2 sites in United States
- Volunteers
- 67 people
- Sponsor
- Temple University
Fibrodysplasia Ossificans Progressiva
An Efficacy and Safety Study of Palovarotene to Treat Preosseous Flare-ups in FOP Subjects
Fibrodysplasia ossificans progressiva (FOP) is a rare, severely disabling disease characterized by painful, recurrent episodes of soft tissue swelling (flare-ups) that result in abnormal bone formation in muscles, tendons, and…
- Trial name
- NCT02190747
- Testing
- Palovarotene
- Where
- 4 sites in United States, France and 1 more
- Volunteers
- 40 people
- Sponsor
- Clementia Pharmaceuticals Inc.
Type 2 Diabetes Mellitus in Obese
REmote SUpport for Low-Carbohydrate Treatment of Type 2 Diabetes
Excess adiposity is a key causal factor in developing type 2 diabetes and weight loss improves glycaemia and can put diabetes in to remission. There is evidence that low carbohydrate diets also reduce glycaemia.
- Trial name
- RESULT (NCT04916314)
- Testing
- Low Carbohydrate diet
- Where
- United Kingdom
- Volunteers
- 115 people
- Sponsor
- University of Oxford
Weight Change, Body
Healthy Homes/Healthy Families (HH/HF) Intervention in 2-1-1 Callers
This trial will evaluate a healthy eating and weight gain prevention intervention for delivery through calls to the 2-1-1 number.
- Trial name
- NCT04373434
- Testing
- Health Homes/Healthy Families (HH/HF) Intervention, Control
- Where
- United States
- Volunteers
- 512 people
- Sponsor
- Emory University
Post Abortion Care
Contraceptive Counseling Following an Abortion
The purpose of this study is to determine whether contraceptive counseling is effective on acceptance and use of methods in women following an abortion.
- Trial name
- APA (NCT00756314)
- Testing
- Personalized contraceptive counseling
- Where
- Brazil
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Anxiety, Self-Efficacy
Musically-Guided Paced Breathing Improves Mental Health in War-Affected Adolescents
Examine the impact of a mindfulness condition, a guided paced breathing audiovisual intervention condition, and a guided paced breathing audiovisual intervention plus take-home application condition compared to a matched control…
- Conditions
- Anxiety, Self-Efficacy, Depression Not Otherwise Specified
- Trial name
- NCT06988800
- Testing
- Paced breathing wellness breathing sessions, Mindfulness video sessions
- Where
- Palestinian Territories
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Muvik Labs
Insomnia, Mental Health Issue
Investigating a Sleep Intervention for Adolescents Attending Mental Health Services
The overall objectives of the study are to: 1. To assess the feasibility of delivering the Strathclyde Sleep Intervention to adolescents with co-morbid insomnia and mental health attending a mental health services The following…
- Trial name
- NCT05870228
- Testing
- Strathclyde Sleep Intervention
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- Stephanie McCrory
Smoking
Computer-Assisted Intervention for Smoking During Pregnancy
This study will develop: 1. Develop the computer-based brief intervention and Contingency Management (CM) components, with repeated feedback from experts, prenatal clinic staff, and participants. 2.
- Trial name
- HPP (NCT01028131)
- Testing
- Computer-delivered brief intervention (5As), Contingency Management
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Wayne State University
Cardiac Diagnostic Procedure, Cardiac Interventional Procedure
The Safety and Efficacy of an Extravascular, Water-Soluble Sealant for Venous Access-Site Closure
Evaluate the safety of the MynxGrip™ extravascular sealant for common femoral vein closure following both diagnostic and interventional procedures as assessed by clinical and imaging criteria.
- Conditions
- Cardiac Diagnostic Procedure, Cardiac Interventional Procedure, Femoral Access Site Closure
- Trial name
- NCT02438475
- Testing
- Mynx Vascular Closure System, Manual Compression
- Where
- 2 sites in United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Severe Aplastic Anemia
Eltrombopag Combined With Cyclosporine as First Line Therapy in Patients With Severe Acquired Aplastic Anemia
The purpose of this study was to evaluate the efficacy and safety of eltrombopag in combination with cyclosporine alone as first-line therapy on overall hematologic response
- Trial name
- SOAR (NCT02998645)
- Testing
- eltrombopag, Cyclosporine
- Where
- 20 sites in Brazil, Hong Kong and 7 more
- Volunteers
- 54 people
- Sponsor
- Novartis Pharmaceuticals
Heart Failure
Efficacy of Oral Bisoprolol on Heart Rate Reduction in Chinese Chronic Heart Failure Participants
This is a single-arm, open label, interventional, multi-center, phase 4 pilot study.
- Trial name
- Biso-CHF (NCT03026088)
- Testing
- Bisoprolol
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Suicide, Psychosis
Cognitive Behavioral Suicide Prevention for Psychosis: Aim 1
The investigators are modifying and testing the preliminary effectiveness and implementation of a Cognitive Behavioral Suicide Prevention for psychosis (CBSPp) intervention.
- Trial name
- NCT04689867
- Testing
- Cognitive Behavioral Suicide Prevention for psychosis CBSPp)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Michigan