Clinical trials: Intervention Effectiveness
Engagement, Positive Parenting
ParentText User Engagement and Effectiveness Study
The study has two main aims. The first aim is to optimise user engagement in ParentText. The goal is to identify the optimal delivery of ParentText for parents/caregivers from low- and middle-income countries, using a randomised…
- Conditions
- Engagement, Positive Parenting, Child Maltreatment, Intimate Partner Violence
- Trial name
- NCT05003518
- Testing
- ParentText
- Where
- Malaysia
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Constipation - Functional
Efficacy of Educational Intervention as Supporting Element in the Treatment of Functional Constipation in Children
The purpose of this study is to determine whether educational intervention (recommendation of adequate fluid intake) is effective as an element supporting the treatment of functional constipation in children.
- Trial name
- NCT05191810
- Testing
- Educational information
- Volunteers
- 110 people
- Sponsor
- Medical University of Warsaw
Self-management, Quality of Life
Stroke - 65 Plus. Continued Active Life.
Since august 2016, the researchers at a highly specialized neurorehabilitation hospital in a Danish region with 1.2 inhabitants have in cooperation with health professionals from a specialized neurorehabilitation in a Danish…
- Trial name
- Stroke65+ (NCT03183960)
- Testing
- Mentor
- Where
- 2 sites in Denmark
- Volunteers
- 69 people
- Sponsor
- Central Jutland Regional Hospital
Underage Drinking
Efficacy of a Web-Based Alcohol Intervention for High School Students
This study evaluates the efficacy of the eCHECKUP TO GO as an intervention to reduce underage drinking and the associated negative consequences among high school seniors.
- Trial name
- NCT03613818
- Testing
- eCHECKUP TO GO
- Where
- United States
- Volunteers
- 311 people, healthy volunteers welcome
- Sponsor
- Boise State University
Stroke, Hemiparesis
Efficacy of a Combined Transcranial Direct Current Stimulation and Virtual Reality Intervention
Rehabilitation options for stroke survivors who present severe hemiparesis in chronic stages are limited and may end in compensation techniques that involve the use of the less affected arm to achieve some degree of functional…
- Conditions
- Stroke, Hemiparesis, Chronic Stroke, Upper Limb Injury
- Trial name
- REACT01 (NCT03528018)
- Testing
- REACt system, Physical therapy
- Where
- Spain
- Volunteers
- 14 people
- Sponsor
- Hospitales Nisa
Mild Cognitive Impairment
Efficacy of the Cognitive Training Based on Location Information and Activity in People With Mild Cognitive Impairment
The purpose of this study is to examine therapeutic efficacy of cognitive Training based on location information and activity in people with mild cognitive impairment
- Trial name
- NCT03928613
- Testing
- tablet based Cognitive Training based on location information
- Where
- South Korea
- Volunteers
- 43 people
- Sponsor
- Seoul National University Bundang Hospital
Procedural Pain, Procedural Anxiety
Effect of Virtual Reality Distraction on Procedural Pain for Children and Adolescents in Onco-Hematology Unit.
Demonstrate the effectiveness of the Virtual Reality (VR) distraction on pain reduction in children and adolescents in onco-hematology unit compared to standard practice.
- Conditions
- Procedural Pain, Procedural Anxiety, Virtual Reality
- Trial name
- ReVaDo (NCT03888690)
- Testing
- Virtual Reality Headset
- Where
- France
- Volunteers
- 96 people
- Sponsor
- Central Hospital, Nancy, France
Rheumatic Heart Disease
Effectiveness of Edutainment-Based Interventions in Increasing Knowledge of Rheumatic Fever and Rheumatic Heart Disease Among School-Going Children in Nepal: Study Protocol for Colors to Save Hearts Quasi-Experimental Pretest-Posttest Study
Background: Acute rheumatic fever (ARF) and its sequela, rheumatic heart disease (RHD), remain significant public health concerns in low- and middle-income countries, including Nepal.
- Trial name
- NCT07065474
- Testing
- education material
- Where
- Nepal
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Kathmandu Institute of Child Health
Emotional Regulation, Examining the Emotion Regulation Effectiveness to be Given to Adolescents
Emotional Management in Adolescents
This study aims to give information about the content of the school-based emotion regulation program study designed for adolescent children to develop their emotion regulation skills.
- Trial name
- NCT06849310
- Testing
- Group that will receive emotional regulation training
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ankara Medipol University
Diabetic Macular Edema
Laser (Selective Retina Therapy) and Drug Combined Intervention in Clinically Significant Diabetic Macular Edema
The objective of this clinical trial is to compare and evaluate the safety and efficacy of Ranibizumab (Lucentis®; Novartis AG, Basel, Switzerland) monotherapy and Ranibizumab combined with R:GEN (Selective Retina Therapy) in…
- Trial name
- NCT03759860
- Testing
- R:GEN laser treatment (Selective Retina Therapy) and Lucentis (ranibizumab) combination therapy
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- CynosureLutronic
Subjective Cognitive Decline (SCD), Subjective Cognitive Impairment
Testing the Cog-Fun Aging Program for Older Adults With Subjective Cognitive Decline
The goal of this clinical trial is to learn if the Cog-Fun Aging program helps older adults with Subjective Cognitive Decline (SCD) manage memory challenges and improve their daily lives.
- Conditions
- Subjective Cognitive Decline (SCD), Subjective Cognitive Impairment, Subjective Memory Complaints
- Trial name
- NCT06816797
- Testing
- Cog Fun Ageing intervention, Cog-Fun Aging Crossover
- Where
- 3 sites in Israel
- Volunteers
- 27 people
- Sponsor
- Hebrew University of Jerusalem
Dental Anxiety
Smartphone Application in Reducing Dental Anxiety
evaluating the effectiveness of smartphone applications (Tell-Play-Do) (TPD) in reduction of preoperative anxiety in children undergoing restorative treatment, as measured by heart rate and Venham's Picture Test.
- Trial name
- NCT04719299
- Testing
- Tell-Play-Do, Tell-Show-Do
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Hams Hamed Abdelrahman
Autism Spectrum Disorder
Efficacy and Mechanism of Repetitive Transcranial Magnetic Stimulation in Children With Autism Spectrum Disorders
This study is a prospective, multicenter, randomized, single-blind controlled trial to enroll 200 children with autism spectrum disorders (ASD).
- Trial name
- NCT05927792
- Testing
- repeated transcranial magnetic stimulation (continuous theta-burst stimulation)
- Where
- 3 sites in China
- Volunteers
- 200 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Executive Function Deficits (EFD)
Unstuck-Early Childhood Effectiveness & Implementation Trial
The goal of this clinical trial is to learn if a new school-based, Tier 2 (selective) cognitive-behavioral intervention called Unstuck and On Target for Early Childhood (Unstuck-EC) can treat executive function deficits in young…
- Trial name
- NCT07832344
- Testing
- Unstuck and On Target for Early Childhood
- Volunteers
- 90 people
- Sponsor
- Children's National Research Institute
Stroke, Intracranial Atherosclerotic Stenosis
SeQuent ® Please CIS for the Treatment of INtracranial Atherosclerotic Stenosis
This study is aiming to evaluate the safety and efficacy of SeQuent® Please CIS in the endovascular treatment of symptomatic intracranial atherosclerotic stenosis and restenosis after interventional therapy.
- Trial name
- SPINAS (NCT06047964)
- Testing
- DCB, POBA
- Where
- 9 sites in China
- Volunteers
- 281 people
- Sponsor
- B. Braun Medical International Trading Company Ltd.
Childhood Obesity
Efficacy of ENTREN-F Program: A Psycho-family Intervention in Childhood Obesity
ENTREN-F Programme describes a novel structured psychosocial family-based intervention from Primary Care using a train trip metaphor aimed at improving healthy lifestyles for the whole family.
- Trial name
- ENTREN-OB (NCT04465799)
- Testing
- ENTREN, ENTREN-F, Control group
- Where
- Spain
- Volunteers
- 180 people
- Sponsor
- Universidad Autonoma de Madrid
Children's Socio-emotional Skills and Psychiatric Symptoms
Yhteispeli - Effectiveness Study on Promoting Childrens' Socio-emotional Skills in School
The purpose of this cluster randomised trial is to investigate whether the Yhteispeli whole school programme is effective in improving children's socio-emotional skills and mental health and socio-emotional skills.
- Trial name
- NCT02178332
- Testing
- Yhteispeli, whole school programme, Two theoretical lectures
- Where
- Finland
- Volunteers
- 4,400 people, healthy volunteers welcome
- Sponsor
- Finnish Institute for Health and Welfare
Fibrodysplasia Ossificans Progressiva
An Efficacy and Safety Study of Palovarotene for the Treatment of Fibrodysplasia Ossificans Progressiva.
Fibrodysplasia Ossificans Progressiva (FOP) is a rare, severely disabling disease characterized by heterotopic ossification (HO) often associated with painful, recurrent episodes of soft tissue swelling (flare-ups) that lead to…
- Trial name
- MOVE (NCT03312634)
- Testing
- Palovarotene
- Where
- 16 sites in United States, Argentina and 9 more
- Volunteers
- 107 people
- Sponsor
- Clementia Pharmaceuticals Inc.
Doctor-patient Communication Improvement
A Study of the Effect of Patient Education (Talking Health Together) in Improving Doctor-patient Communication
This study is being carried out to see if patients make the lifestyle changes or take their medication as instructed by their doctor during their visit as a result of the T.H.T. patient-education training.
- Trial name
- NCT00879736
- Testing
- THT PACE Training
- Where
- 5 sites in Canada
- Volunteers
- 322 people
- Sponsor
- AstraZeneca
Suspected CSF Shunt Obstruction
ShuntCheck-Micro-Pumper Pediatric Clinical Outcomes Study
Primary objective is to demonstrate that data collected from ShuntCheck-Micro-Pumper (SCMP) testing results can be used in conjunction with imaging to diagnose shunt patency or obstruction in pediatric/adolescent subjects…
- Trial name
- NCT01881711
- Testing
- ShuntCheck-Micro-Pumper (SCMP), Imaging
- Where
- 11 sites in United States
- Volunteers
- 400 people
- Sponsor
- NeuroDx Development
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