Clinical trials: Intervention Effectiveness
Coronary Artery Disease, Angina, Unstable
Study on Safety and Effectiveness of Three Doses of Argatroban as Anticoagulant in Percutaneous Coronary Intervention (PCI)
This is a phase II multi-centre study in 140 patients undergoing elective PCI to obtain the information on dose-response of argatroban in pharmacodynamic markers and to assess the anticoagulation, safety and efficacy of…
- Trial name
- NCT00508924
- Testing
- Argatroban, Heparin
- Where
- 8 sites in Belgium, Germany
- Volunteers
- 140 people
- Sponsor
- Tanabe Pharma Corporation
COVID-19 Pandemic, Transplant-Related Disorder
EVALUATION OF DIFFERENT PROPHYLACTIC INTERVENTIONS TOWARD COVID-19 IN SOLID ORGAN TRANSPLANT PATIENTS
The goal of this observational study is to evaluate the immune response after COVID-19 vaccination in Liver(LT) and Kidney(KT) transplant recipient.
- Trial name
- NCT05629923
- Testing
- tixagevimab-cilgavimab(AZD7442, AstraZeneca)
- Where
- Italy
- Volunteers
- 306 people
- Sponsor
- University of Rome Tor Vergata
Hypertension
COmpliance and Efficacy in Mono and Combination Tablet Study ATacand/Atacand Plus
To evaluate compliance and patients' satisfaction in mono and combination treatment of Candesartan cilexetil (Atacand)/ Candesartan cilexetil 16mg, hydrochlorothiazide 12.5mg (Atacand plus) in hypertension.
- Trial name
- COMBAT (NCT00526279)
- Where
- 3 sites in South Korea
- Volunteers
- 9,000 people
- Sponsor
- AstraZeneca
Coronary Disease
Multi-Center Clinical Trial: Evaluation of Effectiveness and Safety
This trial aims to demonstrate the non-inferiority of the CI-CMS-005 Coronary Stent System to the study device as well as to the TAXUS™ Express2™ Drug-Eluting Coronary Stent System in in-segment late lumen loss at 9 months after…
- Trial name
- NCT00415961
- Testing
- CoStar Paclitaxel Drug-Eluting Coronary Stent System
- Where
- Japan
- Volunteers
- 120 people
- Sponsor
- Conor Medsystems
HIV, Patient Compliance
Intervention to Improve Engagement in Care Among Newly Diagnosed HIV-positive Men
The study involves delivering one of two interventions - either Promoting Action Towards Health (PATH) or Personalized Cognitive Counseling (PCC) - to 440 men who have sex with men (MSM) who have recently been diagnosed with HIV…
- Trial name
- NCT01559805
- Testing
- Positive Choices, Personalized Cognitive Counseling
- Where
- 4 sites in United States
- Volunteers
- 202 people
- Sponsor
- Columbia University
Pulmonary Mucormycosis
Efficacy and Safety of Systematic Therapy and Bronchoscopic Interventional Treatment for Pulmonary Mucormycosis
Evaluation of the effectiveness and safety of transbronchoscopic local precision infusion of amphotericin B + transoral nebulized inhalation of amphotericin B + transbronchoscopic interventional debridement + liposomal…
- Trial name
- NCT06495905
- Testing
- transbronchoscopic interventional debridement
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Mental Health Issue, Young Adult
A Feasibility Study for Evaluating the Effectiveness of Mindhelper - a National Youth Mental Health Promotion Website
The feasibility study will investigate the potential of online recruitment for a randomized trial of the effectiveness of Mindhelper.
- Conditions
- Mental Health Issue, Young Adult, Feasibility Studies, Randomized Controlled Trial
- Trial name
- NCT04650906
- Testing
- Mindhelper - a national youth mental health promotion website
- Where
- 2 sites in Denmark
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Bulimia Nervosa
Smartphone-based Aftercare for Inpatients With Bulimia Nervosa
Inpatient treatment for patients with bulimia nervosa (BN) is recommended in extreme or severe cases and/or after failure of outpatient treatment and is highly effective.
- Trial name
- SMART-BN (NCT05728021)
- Testing
- Recovery Record Aftercare, Treatment as usual (TAU)
- Where
- 4 sites in Germany
- Volunteers
- 172 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Social Anxiety Disorder
Effect of Nursing Interventions Using Roy Adaptation Model with Virtual Reality on Social Anxiety in Youth
The study was conducted to determine the effect of nursing practices based on the RAM integrated with VR on the social anxiety level of young people.The main questions it aims to answer are: H1: "Nursing practices based on the…
- Trial name
- NCT06586944
- Testing
- Nursing Practices Based On Roy Adaptation Model Integrated With Virtual Reality, Roy Adaptation Model
- Where
- Turkey (Türkiye)
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Aytuğ Türk
Frailty, Pre-Frailty
In-Person, Online, and Hybrid Healthy-Aging Education for Pre-Frailty and Frailty in Older Adults
The goal of this clinical trial is to determine whether a 6-month healthy-aging education program delivered in person, online, or in a hybrid format reduces frailty and is cost-effective compared with usual care in…
- Trial name
- FRAGSALUD-ON (NCT07738393)
- Testing
- In-person healthy aging education program, Hybrid healthy aging education program, Online healthy aging education program
- Where
- Spain
- Volunteers
- 276 people
- Sponsor
- University of Cadiz
Resilience
"resiLIR Healthcare Professionals": A Psychological Online Intervention to Enhance Resilience in Healthcare Professionals
The goal of this clinical trial is to evaluate an online resilience intervention with healthcare professionals. Participants will receive a 6-week online intervention addressing resilience and stress with a specific focus on…
- Trial name
- NCT05812716
- Testing
- resiLIR Healthcare Professionals
- Where
- Germany
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Leibniz-Institut für Resilienzforschung (LIR) gGmbH
COVID-19
Developing an Effective Intervention to Address Post-Corona-Virus-Disease-2019 Balance Disorders, Weakness and Muscle Fatigue in Individuals Aged 65+
The long-term consequences and sequelae of COVID-19 are still unclear; however, a vast number of elderly individuals have reported prolonged general weakness and muscular fatigue, leading to significant functional decline…
- Trial name
- NCT05934279
- Testing
- Resistance Training
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Józef Piłsudski University of Physical Education
Paroxysmal Atrial Fibrillation
Safety and Efficacy Study of the Combined Ablation Procedure to Treat Paroxysmal Atrial Fibrillation
This is a multi-center, prospective, open label, feasibility clinical study,evaluating the safety and efficacy of the combined ablation procedure for the treatment of symptomatic paroxysmal atrial fibrillation.
- Trial name
- CAP STOPS AF (NCT01103674)
- Testing
- Numeris®-AF Guided Coagulation System with VisiTrax®
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- nContact Surgical Inc.
Body Esteem
A School Program for Teenagers to Promote Positive Body Image Using Social Media Education and Self-Compassion-Based Activities
Background and study aims Many teenagers feel unhappy with their bodies, which can lead to problems like eating disorders, low self-esteem, and depression.
- Trial name
- IMPACTREEL (NCT07103213)
- Testing
- IMPACTREEL programme
- Where
- Spain
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Universidad Miguel Hernandez de Elche
Diabetes Mellitus Type 2
Continuous Care Intervention in Primary Care to Improve Type 2 Diabetes Control in Terres de l'Ebre, Catalonia
This randomized, parallel-group clinical trial evaluates the effectiveness of a continuity of care intervention to improve metabolic control in adults with type 2 diabetes mellitus (T2DM) in the Terres de l'Ebre health region.
- Trial name
- NCT07124923
- Testing
- Continuity-of-Care intervention
- Where
- 12 sites in Spain
- Volunteers
- 7,792 people
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Depression in Old Age
Programme Evaluation on Effectiveness of The Use of Movement-based x 'Elderspirituality - Fu Le Mun Sum' Intervention to Support Elderly People With Depressive Symptoms
Depression is one of the most common mood disorders in old age, and yet it is frequently under-detected and under-treated. Adopting a train-the-trainer approach, this project intends to utilize the dance movement therapy (DMT)…
- Trial name
- NCT05308082
- Testing
- Dance Movement Therapy (DMT)
- Where
- Hong Kong
- Volunteers
- 135 people
- Sponsor
- The University of Hong Kong
Chemotherapy Induced Peripheral Neuropathy (CIPN)
Improving Chemotherapy Induced Peripheral Neuropathy in Children With Leukemia: A Study of Transcutaneous Acupoints Electrical Stimulation and Auricular Acupressure Interventions
The goal of this clinical trial is to compare the effectiveness of Transcutaneous Acupoints Electrical Stimulation (TAES) and Auricular Acupressure (AA) on subject CIPN symptoms, sensory function, motor and physical function…
- Trial name
- NCT07279818
- Testing
- Transcutaneous Acupoints Electrical Stimulation (TAES), Auricular Acupressure (AA), No intervention
- Where
- China
- Volunteers
- 132 people
- Sponsor
- The Hong Kong Polytechnic University
Advanced Cancer
FOCUSau: A Dyadic Digital Health Intervention to Improve the Wellbeing of People With Advanced Cancer and Their Carers
FOCUS is a dyadic, psychoeducational intervention developed in the USA, shown to improve the wellbeing and quality of life (QoL) of patients with advanced cancer and their primary family carers.
- Trial name
- FOCUSau (NCT06082128)
- Testing
- FOCUSau
- Where
- 5 sites in Australia
- Volunteers
- 433 people
- Sponsor
- University of Melbourne
Aged, Experiential Learning
Community Beauty and Health Program for Older Adults: An Experiential Learning Trial
This study develops and evaluates a "Senior Beauty and Health Care" course designed to improve students' awareness, attitudes, and skills in caring for older adults' appearance and well-being.
- Conditions
- Aged, Experiential Learning, Health Education
- Trial name
- NCT07053592
- Testing
- Geriatric Ｂeauty and Ｈealth Care Learning Program
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung University of Science and Technology
Internal Carotid Artery Stenosis
Safety and Efficacy of Carotid Artery Stenting Combined With Intermittent Hypoxia Intervention in Patients With Severe Internal Carotid Artery Stenosis
This study aims to explore the efficacy of Intermittent Hypoxia Treatment (IHT) in preventing peri-operative embolism-related microinfarcts among patients with severe internal carotid artery stenosis (ICAS) undergoing carotid…
- Trial name
- NCT07837011
- Testing
- intermittent hypoxia intervention, Carotid Artery Stenting (CAS), Standard Medical Therapy
- Where
- China
- Volunteers
- 176 people
- Sponsor
- Capital Medical University
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