Clinical trials: Intervention Effectiveness
Cancer Pain
An Interventional Study for Patient With Cancer Pain to Evaluate the Efficacy and Safety of OxyNorm® Compared to Morphine Sulfate Through the IV Continuous Infusion.
The purpose of this study is to compare of difference in NRS scores from baseline to the completion of treatment (5 days) in patients with administration of morphine sulfate versus oxycodone hydrochloride.
- Trial name
- SWITCH (NCT02660229)
- Testing
- Oxycodone Hydrochloride, Morphine Sulphate
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Mundipharma Korea Ltd
Percutaneous Coronary Intervention, Dual Antiplatelet Therapy
Efficacy and Safety of Short Duration of DAPT After GENOSS® DES Implantation in Patients with Coronary Artery Disease
The objective of study is to evaluate the efficacy and safety of short duration of DAPT after GENOSS® DES Implantation in patients with coronary artery disease.
- Trial name
- DAPTShort (NCT06075420)
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Genoss Co., Ltd.
Depression, Anxiety, Mental Health Issue
Clinical Outcomes of a Digital Mental Health Intervention for Moderate/Severe Depression and Anxiety
A digital mental health intervention (BetterHelp, Mountain View, CA) provides users with access to online therapy care for treatment of depression and anxiety.
- Conditions
- Depression, Anxiety, Mental Health Issue, Mental Health Wellness 2
- Trial name
- NCT07081061
- Testing
- BetterHelp
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Teladoc Health
Overweight, Obesity
Brain Breaks Exercise Videos for Overweight and Obese Children
This randomized controlled study evaluated the effects of a 4-week Brain Breaks® exercise video intervention on physical activity and Transtheoretical Model-related psychosocial factors among overweight and obese children and…
- Trial name
- NCT07826624
- Testing
- Video-Guided Physical Activity Program
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Guangzhou University
HIV Infections
Efficacy of Serious Game Interventions on HCV Education for HIV Patients
Hepatitis C transmission has a high rate of infection and re-infection among PLWH men who have sex with men (MSM), and co-infection increases liver and HIV morbidity.
- Trial name
- NCT05497388
- Testing
- Serious Game
- Where
- Taiwan
- Volunteers
- 162 people
- Sponsor
- National Taiwan University Hospital
Proprioceptive Disorders
Proprioceptive Neuromuscular Facilitation in the Flexibility and Strength of Flexor Muscles and Hamstrings
Introduction: The loss of normal values of ROM due to the lack of flexibility and strength in the hip flexors, quadriceps and hamstrings in soccer players can cause a loss of mobility of the hip and knee joint.
- Trial name
- NCT03875170
- Testing
- Experimental, Control
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Investigación en Hemofilia y Fisioterapia
HPV-Related Cervical Carcinoma
Effectiveness of Targeted Educational Interventions at Increasing HPV Vaccine Acceptability and Uptake
This study aims to assess the effectiveness of targeted educational interventions in increasing the acceptability and knowledge of the HPV vaccine among females ages 12 through 26.
- Trial name
- NCT03337269
- Testing
- Educational video, Educational handout, Control
- Where
- United States
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Overweight and Obesity During Pregnancy
Effectiveness of Nutrition Counseling on Gestational Weight Gain Among Overweight and Obese Pregnant Women in Lebanon
A high percentage of women are either overweight or obese before pregnancy and many women are exceeding the gestational weight gain recommendations when pregnant.
- Trial name
- NCT07279337
- Testing
- Intervention group that received detailed nutrition assessment, counseling, and monitoring
- Where
- Lebanon
- Volunteers
- 60 people
- Sponsor
- University of Nicosia
Cancer Screening, Lung Cancer
Precision Navigation to Improve Community Cancer Screening Participation
This study will evaluate whether a precision navigation intervention can help community residents at high risk for cancer complete recommended cancer screening.
- Conditions
- Cancer Screening, Lung Cancer, Breast Cancer, Colorectal Cancer
- Trial name
- NCT07676383
- Testing
- Precision Navigation Intervention, Usual Health Education
- Where
- 3 sites in China
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Hunan Cancer Hospital
Atopic Dermatitis
Real-world Effectiveness Study of Long-term Treatment With Dupilumab in Participants ≥6 Years With Atopic Dermatitis
This is a Prospective, non-interventional (NIS) observational study in patients (≥6 years) with atopic dermatitis (AD) receiving dupilumab for the prospective evaluation of signs and symptoms, quality of life and disease control.
- Trial name
- PROTYPE2 (NCT06039241)
- Where
- 55 sites in Germany
- Volunteers
- 572 people
- Sponsor
- Sanofi
Chronic Pain
Mindfulness Self-Compassion Intervention Versus a Cognitive-Behavioral Intervention to Improve Self-care in Chronic Pain
Approximately 10-23% of people suffer from chronic pain in our country. Chronic pain is associated with emotional distress (anxiety and depression), physical and social impairment and reduction of quality of life in patients who…
- Trial name
- NCT03386422
- Testing
- MSC, CBT
- Where
- Spain
- Volunteers
- 159 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Child Anxiety, Depression
Kind Minds Program for Youth With Anxiety and Depression
Rates of anxiety and depression in youth are substantial, causing a major unmet need for effective interventions. Participation in mindfulness interventions has been demonstrated to reduce anxiety and depressive symptoms among…
- Trial name
- KMP (NCT05353751)
- Testing
- Kind Minds Program
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of California, Los Angeles
PostPartum Depression
The Effect of Exercise on Preventing PostPartum Depression
The purpose of this study is to examine the feasibility and efficacy of an exercise intervention for the prevention of postpartum depression.
- Trial name
- NCT00961402
- Testing
- Wellness Control, Exercise Intervention
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Myoma;Uterus
Safety & Efficacy of Non-Invasive Procedures Using Ultrasound-Guided HIFU 'Sonotrip V20' in Symptomatic Uterine Fibroids
This is a single-arm clinical trial evaluating the safety and efficacy of ultrasound-guided HIFU (Sonotrip V20) for symptomatic uterine fibroids. 57 cases will be enrolled at a Korean institution.
- Trial name
- NCT05972642
- Testing
- HIFU-treatment
- Volunteers
- 30 people
- Sponsor
- Seoul National University Hospital
Ischemic Heart Disease Chronic
Effectiveness and Cost-effectiveness of a VCoP to Empowerment of Patients With Ischaemic Heart Disease in PHC: Cluster-RCT
Objective: to evaluate the effectiveness and estimate the costs of a Virtual Community of Practice in the improvement of the activation of patients with Ischemic Heart Disease in Primary Care .
- Trial name
- Empodera-dos (NCT03959631)
- Testing
- Virtual Communities of practice
- Where
- Spain
- Volunteers
- 123 people
- Sponsor
- Gerencia de Atención Primaria, Madrid
Post Operative Pain, Opioid Analgesic Adverse Reaction
Postoperative Analgesia Intervention With Non-opioid Alternatives (PAIN-Alt) Trial - Breast Surgery
North America is experiencing a crisis of opioid use and abuse, partially caused by excessive prescribing by doctors. People often receive their first opioid prescription for pain treatment after outpatient breast surgery (i.e.…
- Conditions
- Post Operative Pain, Opioid Analgesic Adverse Reaction, Surgery, Postoperative Pain
- Trial name
- PAIN-Alt (NCT06507345)
- Testing
- Opioid Analgesia (OA) [Multimodal analgesia including opioid drugs], Opioid-Free Analgesia (OFA) [Multimodal analgesia not including opioid drugs]
- Where
- Canada
- Volunteers
- 540 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Adhesive Capsulitis
Ultrasound-guided Hydrodistension in Patients With Adhesive Capsulitis
The present study aims to compare the efficacy of assisted rehabilitation treatment, in terms of improvement of pain and shoulder articulation, in patients with stage 2 adhesive capsulitis compared with unassisted home…
- Trial name
- CAVD21 (NCT06062654)
- Testing
- Hospital-assisted Rehabilitation, Home-based Rehabilitation
- Where
- Italy
- Volunteers
- 46 people
- Sponsor
- Istituto Ortopedico Rizzoli
Musculoskeletal Pain
Effectiveness of an Interdisciplinary Pain Education Program in Public Health: a Pragmatic Clinical Trial
The objective of this study is to evaluate the effectiveness of an interdisciplinary pain education program in improving self-efficacy and promoting quality of life in patients with chronic musculoskeletal pain in public health.
- Trial name
- NCT05544383
- Testing
- Interdisciplinary Pain Education Program, Conventional Physiotherapy treatment
- Volunteers
- 108 people
- Sponsor
- Federal University of Espirito Santo
Diabetes
EFFECTIVENESS OF A TRIPLE NUTRITIONAL INTERVENTION AND PHYSICAL IN PREDIABETIC PATIENRS
Diabetes represents a substantial burden on health care systems. People with prediabetes IGT (impaired glucose tolerance) or IFG (impaired fasting glucose) are at high risk of developing diabetes, and up to 50% progress to…
- Trial name
- NCT06820775
- Testing
- A TRIPLE INTERVENTION NUTRITION AND PHYSICAL ACTIVITY
- Where
- Spain
- Volunteers
- 82 people
- Sponsor
- Bioaraba Health Research Institute
Staff Support
A Pilot RCT Examining the Effectiveness of CMT for Healthcare Staff
The COVID-19 pandemic has highlighted the critical need for evidence-based interventions to support the psychological wellbeing of healthcare staff, particularly within Occupational Health settings.
- Trial name
- NCT07411183
- Testing
- Compassionate Mind Training, Staffcare Counselling
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
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