Clinical trials: Intervention Effectiveness
Internet-based Treatment for Depression
Internet Delivered Intervention Program for the Prevention and Treatment of Depression
The purpose of this study is to determine the differential effectiveness of a self applied treatment delivered via Internet for the prevention and treatment of depression, with or without support by the therapist, compared to a…
- Trial name
- NCT02148354
- Testing
- Smiling is Fun
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Universitat Jaume I
Plantar Fasciopathy
Efficacy of a Self-managed Versus a Predetermined Resistance Training Protocol in Reducing Pain in Individuals With Plantar Fasciopathy
The purpose of this trial is to investigate whether a self-managed resistance training protocol is more effective than a predetermined resistance training protocol in improving the Foot Health Status Questionnaire pain domain…
- Trial name
- NCT03304353
- Testing
- Self-managed protocol, Predetermined protocol
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Aalborg University
Tinnitus
FR-taVNS Tinnitus Tria
Tinnitus is a common neurosensory symptom affecting 12-30% of adults and is closely associated with anxiety, sleep disturbance, and autonomic dysregulation.
- Trial name
- NCT07711639
- Testing
- True Foot Reflexology, True ta-VNS, True Auricular Acupressure
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- Tzu Chi University
Drug Safety
Data-driven Quality Improvement in Primary Care - Trial
A cluster randomised controlled trial to test the effectiveness of an informatics tool, educational and financial incentives to reduce high risk prescribing of non-steroidal anti-inflammatory drugs and anti-platelet agents.
- Trial name
- DQIP (NCT01425502)
- Testing
- DQIP Intervention
- Where
- 2 sites in United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Dundee
Dietary and Lifestyle Behaviour Change
Personalised Behavioural Intervention in Cancer Screening Programmes
The aim of this clinical trial is to find out whether CANVIA can help adults improve dietary and lifestyle habits related to cancer prevention.
- Trial name
- CANVIA (NCT07722442)
- Testing
- Personalised baseline feedback report, CANVIA mobile app intervention, Additional health professional support
- Where
- Spain
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears
Depression
Empower@Home: Hybrid Effectiveness-Implementation Randomized Controlled Trial (RCT)
This study is a randomized Type I hybrid effectiveness-implementation trial aimed at evaluating the effectiveness of Empower@Home, an internet-delivered cognitive-behavioral therapy (CBT) program supported by aging service…
- Trial name
- NCT06584422
- Testing
- Empower@Home: An online cognitive-behavioral therapy self-care program for geriatric depression, Telephone friendly visits
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- University of Michigan
Knee Osteoarthritis
Observation of the Clinical Efficacy of Two Surgical Procedures for Varus Knee Osteoarthritis
The purpose of this study is to conduct a prospective randomized controlled trial to compare the effects between two surgical procedures in the treatment of varus knee osteoarthritis.The hypothesis was that there would be no…
- Trial name
- NCT05382429
- Testing
- OWHTO, CWHTO
- Where
- China
- Volunteers
- 160 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Kidney Failure, End Stage Renal Disease
Enhancing the Cardiovascular Safety of Hemodialysis Care (Dialysafe)
The purpose of this study is reduce episodes of intradialytic hypotension, low blood pressure during a hemodialysis session, in patients with End Stage Renal Disease (ESRD).
- Conditions
- Kidney Failure, End Stage Renal Disease, Hypotension, Cardiovascular Diseases
- Trial name
- Dialysafe (NCT03171545)
- Testing
- Patient Activation, Provider Education
- Where
- United States
- Volunteers
- 1,431 people
- Sponsor
- University of Michigan
Football Player
Plyometric Training, in the Improvement of Explosive Strength and Speed in Soccer Players
Football requires a high number of actions at high speed and intensity. The application of plyometrics can improve explosive strength and speed levels in soccer players.
- Trial name
- NCT04289896
- Testing
- Plyometric exercise
- Where
- Spain
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Investigación en Hemofilia y Fisioterapia
Suicide, Attempted
Study About Treatment After a Suicide Attempt
Effective, brief, low-cost interventions for individuals who attempt suicide are needed to save lives and achieve the goals of the National Strategy for Suicide Prevention.
- Trial name
- NCT03894462
- Testing
- Attempted Suicide Short Intervention Program, Zero Suicide Usual Care
- Where
- 3 sites in United States
- Volunteers
- 443 people
- Sponsor
- University of Rochester
Stroke
Behavioral Intervention and Guided Stepping Training Early Post-Stroke
Low daily steps and prolonged sedentary behavior are associated with reduced functional outcomes and quality of life in patients with stroke.
- Trial name
- BIG STEPS (NCT07702643)
- Testing
- Behavior and guided stepping training intervention (BIG STEPS), DELAYED Behavior and guided stepping training intervention
- Where
- 6 sites in Canada
- Volunteers
- 150 people
- Sponsor
- University of Alberta
Hypochondroplasia
An Interventional Study of Infigratinib in Children With Hypochondroplasia
ACCEL2/3 is a Phase 2/3 study. The purpose of the Phase 2 portion of the study (ACCEL2/3) is to evaluate the efficacy and safety of infigratinib in children with hypochondroplasia (HCH) receiving infigratinib at one of two doses…
- Trial name
- HCH (NCT06873035)
- Testing
- infigratinib 0.128 mg/kg/day, infigratinib 0.25 mg/kg/day
- Where
- 24 sites in United States, Australia and 8 more
- Volunteers
- 24 people
- Sponsor
- QED Therapeutics, a BridgeBio company
Wound, Wound and Injuries
Virtual Pain Care Trial
The main objective of this study is to evaluate the effect on pain of Virtual Reality Therapy as add-on therapy during wound care procedures in adults.
- Conditions
- Wound, Wound and Injuries, Pain
- Trial name
- NCT05772468
- Testing
- Virtual Reality ('VRelax' VR system)
- Where
- Netherlands
- Volunteers
- 32 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Cataract, Posterior Capsule Opacification
Two Different Cataract Surgical Procedures to Prevent Posterior Capsule Opacification
In this study, the investigators introduce a new "capsule-reserved" cataract surgical procedure in which anterior lens capsule is reserved and attached onto posterior lens capsule in the purpose of preventing posterior capsule…
- Trial name
- NCT02445274
- Testing
- Anterior lens capsule was reserved
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Sun Yat-sen University
Hospital Fire Safety Preparedness
Augmented Reality for Hospital Fire Safety
This study evaluated the effectiveness of augmented reality-based hospital fire-safety education among hospitalized patients and accompanying caregivers.
- Trial name
- NCT07732959
- Testing
- Augmented Reality Fire-Safety Education, Traditional Fire-Safety Education
- Where
- Taiwan
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Chou Yun Jyuan
Elder Abuse, Self Neglect
Effectiveness of RISE as a Community-Based Stand-Alone Elder Abuse Intervention Model
The goal of this randomized clinical trial is to learn if the RISE intervention can improve the well being of older adults who are at risk of or experiencing elder abuse or self-neglect (EASN).
- Trial name
- NCT07527962
- Testing
- RISE Model, Brief Consultation and Resource Sharing
- Where
- 2 sites in Canada
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- RISE Collaborative
Hypertension, Hypercholesterolemia
Multicenter, Prospective, Non-interventional, Observational Study to Confirm the Long-term Efficacy and Safety of Rosuampin Tab. in Patients With Hypertension and Hypercholesterolemia
This study is to confirm the long-term efficacy and safety of Rosuampin Tab. in patients with hypertension and hypercholesterolemia
- Trial name
- NCT06293261
- Testing
- Rosuampin 5/5mg, 10/5mg, 20/5mg, 10/10mg
- Where
- 39 sites in South Korea
- Volunteers
- 5,047 people
- Sponsor
- Yuhan Corporation
Lupus Erythematosus, Systemic
NIS to Examine Disease Activity in SLE Patients Treated With Subcutaneous Anifrolumab in Routine Care
VIOLET is a prospective, single-arm, multi-centre, non-interventional study (NIS) evaluating real-world clinical and patient-reported outcome (PRO) data in adult patients who are initiated on subcutaneous anifrolumab treatment of…
- Trial name
- VIOLET (NCT07424261)
- Where
- 21 sites in Germany
- Volunteers
- 125 people
- Sponsor
- AstraZeneca
COVID-19 Infection
A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised
This is a Phase 3, randomized, actively controlled, double-blinded, double-dummy, superiority study to evaluate the efficacy and safety of ibuzatrelvir alone and in combination with remdesivir IV compared to remdesivir IV alone…
- Trial name
- NCT07013474
- Testing
- ibuzatrelvir, remdesivir
- Where
- 159 sites in United States, Argentina and 16 more
- Volunteers
- 300 people
- Sponsor
- Pfizer
Presbyopia
LaserACE® Procedure Restore Visual Function and Range of Accommodation LaserACE® Procedure
A new minimally invasive procedure for treating presbyopia is being evaluated to determine if there is improvement in near and intermediate vision after treatment.
- Trial name
- NCT01491360
- Testing
- LaserACE(R)
- Where
- Taiwan
- Volunteers
- 8 people
- Sponsor
- ACE Vision Group, Inc.
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