Clinical trials: Interventional Study
Obesity
Personalized Nutrition and eHealth: Lifestyle Intervention (LION) Study for Weight Loss Maintenance
Despite standardized intervention strategies, weight loss and weight loss maintenance largely differ from person to person. Factors which may contribute to these individual differences is current object of research.
- Trial name
- LION (NCT04023942)
- Testing
- Weight maintenance intervention
- Where
- Germany
- Volunteers
- 272 people
- Sponsor
- Technical University of Munich
Psoriasis
A Study of Guselkumab for the Treatment of Palmoplantar-non-Pustular Psoriasis
The purpose of this study is to evaluate the efficacy of guselkumab for the treatment of palmoplantar psoriasis.
- Trial name
- G-PLUS (NCT03998683)
- Testing
- Guselkumab 100 mg
- Where
- 26 sites in France, Germany and 3 more
- Volunteers
- 117 people
- Sponsor
- Janssen-Cilag Ltd.
Renal Injury
Different Vascular and Renal Parameters in Living Kidney Donors
Chronic kidney disease (CKD) has a high prevalence globally and is a global health concern. CKD is associated with increased risks of cardiovascular morbidity, mortality and therefore decreased quality of life in any stage of the…
- Trial name
- NCT06056466
- Where
- Germany
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Hereditary Tyrosinemia, Type I
A Non-interventional, Post-Marketing Study to Describe Outcome of Nitisinone Treatment in HT-1 Patients
This is a prospective, non-interventional, non-comparative, multicenter study to collect data on HT-1 patients in China treated with Nitisinone in a routine clinical setting. No tests or examinations are mandated in the study.
- Trial name
- NCT06227429
- Testing
- Nitisinone
- Where
- 4 sites in China
- Sponsor
- Swedish Orphan Biovitrum
Eating Disorders, Binge Eating
Study of Efficacy and Safety of WELT-ED for Eating Disorder (WCTP-ED-B-01)
The purpose of this clinical trial is to evaluate the safety and efficacy of a digital therapeutic device (WELT-ED) based on Cognitive Behavioral Therapy (CBT) for the treatment of eating disorders.
- Conditions
- Eating Disorders, Binge Eating, Binge-Eating Disorder
- Trial name
- NCT06294353
- Testing
- WELT-ED (CBT based DTx), Standard Treatment
- Where
- 2 sites in South Korea
- Volunteers
- 134 people
- Sponsor
- WELT corp
Older Adults
Exercise Intervention for Pre-frail Elderly
The aim of this study is to evaluate the effectiveness of multicomponet exercise for reversing pre-frailty among Chinese community-dwelling pre-frail older adults.Meanwhile,to explore the effects of multicomponent exercise on…
- Trial name
- NCT06519695
- Testing
- Multicomponent exercises
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Hangzhou Normal University
Children Sedation
Comparison of Chlorpromazine or Pentobarbital Premedications for Pediatric Imaging Procedures
Sedation is often required for pediatric medical imaging procedures to ensure compliance and quality images. Recommendations exist regarding pediatric sedation, but there are currently no guidelines regarding the choice of the…
- Trial name
- PREIMAPED (NCT04350528)
- Testing
- Chlorpromazine or Pentobarbital
- Where
- France
- Volunteers
- 254 people
- Sponsor
- University Hospital, Brest
Laparoscopic Entry Technique
COMPARATIVE STUDY BETWEEN TERNAMIAN BLADELESS TROCAR ENTRY and VISUAL TRANSPARENT BLADED TROCAR ENTRY in LAPAROSCOPIC PROCEDURES
To compare the efficacy and safety between Ternamian bladeless trocar entry and visual, transparent bladed trocar entry in laparoscopic procedures.
- Trial name
- NCT06645392
- Testing
- visual transparent bladed trocar of, Ternamian bladeless trocar
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Severe Obesity, Bariatric Surgery
Study on Impact of Lifestyle Change and Weight Loss Before Bariatric Surgery
The purpose of the trial is to determine whether a preoperative lifestyle intervention (targeting diet, exercise, and preparation for surgery) will favorably impact obesity-related parameters prior to bariatric surgery and…
- Trial name
- PREP (NCT00623792)
- Testing
- Preoperative lifestyle Intervention
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Duquesne University
Congenital Bleeding Disorder, Haemophilia A With Inhibitors
Non-Interventional Study of NovoSeven® Used as On-demand Treatment of Bleeds in Patients With Haemophilia A and B With Inhibitors
This study is conducted in Japan. The aim of this registry study is to observe the use of single dose and multi-dose use of eptacog alpha (NovoSeven®) and to compare short-term outcomes, including effectiveness, safety, quality…
- Conditions
- Congenital Bleeding Disorder, Haemophilia A With Inhibitors, Haemophilia B With Inhibitors
- Trial name
- NCT01586936
- Testing
- eptacog alfa (activated)
- Where
- Japan
- Volunteers
- 9 people
- Sponsor
- Novo Nordisk A/S
Healthy
A Study Validating the Use of Candin as a Challenge Agent in Healthy Participants - Intervention Specific Appendix 2
The purpose of this study is to characterize the delayed-type hypersensitivity (DTH) response at the site of Candin intradermal injection in the presence of a targeted immune pathway inhibitor.
- Trial name
- NCT04611971
- Testing
- Benlysta, Candin
- Where
- Belgium
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Mortality, Complication, Postoperative
Periinterventional Outcome Study in the Elderly
The POSE study will predict critical stages and outcome in a large sample of all surgical and non-surgical interventional patients ≥80 years of age in Europe.
- Trial name
- POSE (NCT03152734)
- Testing
- Surgical or non-surgical intervention
- Where
- 177 sites in Austria, Belgium and 18 more
- Volunteers
- 9,500 people
- Sponsor
- Mark Coburn
Fluid Therapy
Fluid Day Spanish Observational Study
Perioperative fluid therapy has undergone a huge change in clinical practice in recent years. The patterns of replacement and / or restoration of volemia described in the classic anaesthesiology books were supported by weak…
- Trial name
- Fluid Day (NCT03630744)
- Testing
- Fluid therapy
- Where
- Spain
- Volunteers
- 3,500 people
- Sponsor
- Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor
Hip Fractures, Knee Arthroplasty
Continuous Spinal Anesthesia Versus Combined Spinal Epidural Block
In major orthopaedic surgery of the lower extremities both continuous spinal anesthesia (CSA) and combined spinal epidural anesthesia (CSE) are safe and reliable anaesthesia methods.
- Conditions
- Hip Fractures, Knee Arthroplasty, Femur Fracture
- Trial name
- Spinocath (NCT00616044)
- Testing
- continuous spinal anesthesia, Spinocath a catheter for continuous spinal anesthesia, combined spinal epidural anesthesia
- Where
- Brazil
- Volunteers
- 240 people
- Sponsor
- Sao Jose do Rio Preto Medical School
Patient Satisfaction
Evaluation of Patient Information in Interventional Radiology
Interventional radiology is developing. Patient information modalities are also evolving, in particular information videos.
- Trial name
- NCT06354075
- Testing
- Questionary
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Alopecia, Chemotherapy Effects
A 6-month Post-interventional Follow-up Extension of VOLUME Study (VOLUME-2)
We would suggest to conduct "VOLUME-2" study, as an extension of the ongoing "VOLUME" study with all subjects already included. After completion of VOLUME study, the study will be directly extend with an "open-label design".
- Trial name
- VOLUME2 (NCT02986412)
- Testing
- CG428
- Where
- South Korea
- Volunteers
- 19 people
- Sponsor
- Samsung Medical Center
Psychological Well-being, Hope Level
A Hope-Fostering Counseling Program to Promote Psychological Well-being Among Post-Abortion Primigravida Mothers: A Pilot Intervention Development and Feasibility Study
This study aims to investigate the feasibility of a hope-fostering counseling program among post-abortion primigravida mothers. The counseling program is composed of 6 counseling sessions based on individualized discussion.
- Conditions
- Psychological Well-being, Hope Level, Post-abortion, Hope Fostering Counseling Program
- Trial name
- NCT07488130
- Testing
- Hope-Fostering Counseling Program
- Where
- Jordan
- Volunteers
- 8 people
- Sponsor
- University of Jordan
Diabetes
Diabetes Survival Skills + (DSS+) Training Intervention for Incarcerated Persons Transitioning to the Community (TTC)
The purpose was to examine the feasibility and acceptability of a Diabetes Survival Skills intervention training with and without a support group for incarcerated persons transitioning to the community.
- Trial name
- NCT05510531
- Testing
- Diabetes Survival Skills Training
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- University of Connecticut
Acute Myelogenous Leukemia (AML), Acute Lymphoblastic Leukemia (ALL)
Non-interventional, Long-term Follow-up of Subjects Who Completed ApoGraft-01 Study
This is a non-interventional, long-term follow-up study in subjects who received ApoGraft in study ApoGraft-01. Up to 12 subjects who completed ApoGraft-01 study will be offered to participate in this follow-up study.
- Conditions
- Acute Myelogenous Leukemia (AML), Acute Lymphoblastic Leukemia (ALL), Non Hodgkin Lymphoma (NHL), Hodgkin Lymphoma, Adult
- Trial name
- NCT03260101
- Testing
- non intervational
- Where
- Israel
- Volunteers
- 12 people
- Sponsor
- Cellect Biotechnology
Stress, Relaxation
Decreasing Stress Via Virtual Reality and Binaural Beats in Non-Clinical Adults
This study is a non-clinical substudy conducted within the DESTRESS research program (NCT05036538), which investigates the effects of relaxation interventions on physiological and psychological parameters.
- Conditions
- Stress, Relaxation, Virtual Reality, Binaural Beats
- Trial name
- DESTUD (NCT07387107)
- Testing
- Virtual Reality-Based Natural Environment, Binaural Auditory Stimulation, Control Condition (No Relaxation Intervention)
- Where
- Germany
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Heart and Brain Research Group, Germany