Clinical trials: Intestinal Motility
Gastroparesis
Evaluation of Single Doses of GSK962040 in Critically Ill Patients With Enteral Feed Intolerance
The aims of MOT112571 are to assess the pharmacodynamic effects, safety, tolerability, pharmacokinetics, and potential therapeutic benefit of single doses of GSK962040 in critically ill patients with delayed gastric emptying and…
- Trial name
- NCT01039805
- Testing
- GSK962040 (50 mg), GSK962040 (75 mg)
- Where
- Australia
- Volunteers
- 34 people
- Sponsor
- GlaxoSmithKline
Irritable Bowel Syndrome, Gallstone Disease
Pharmacokinetics, Bioequivalence, and Safety Study of Trimedat® 76,95 mg Orally Disintegrating Tablets and Trimedat® 100 mg Tablets in Healthy Volunteers.
This study aims to evaluate pharmacokinetic profile, safety and establish bioequivalence of the investigational drug Trimedat® 76,95 mg orally disintegrating tablets compared to the reference drug Trimedat® 100 mg tablets in…
- Conditions
- Irritable Bowel Syndrome, Gallstone Disease, GERD, Biliary Dyskinesia
- Trial name
- NCT07421011
- Testing
- Trimedat®
- Where
- Russia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Valenta Pharm JSC
Hypertension, Depression
Patient-Centred Innovations for Persons With Multimorbidity - Quebec
The aim of Patient-Centred Innovations for Persons With Multimorbidity (PACE in MM) study is to reorient the health care system from a single disease focus to a multimorbidity focus; centre on not only disease but also the…
- Conditions
- Hypertension, Depression, Anxiety, Musculoskeletal Pain
- Trial name
- PACEinMM-QC (NCT02789800)
- Testing
- DIMAC02
- Where
- 2 sites in Canada
- Volunteers
- 284 people
- Sponsor
- Université de Sherbrooke
GERD
Electronic Health Record (EHR)-Based Intervention for Gastroesophageal Reflux Disease (GERD) and Chronic Non-steroidal Anti-inflammatory Drug (NSAID) Use
The purpose of the study is to examine the impact of augmented, high-quality physician-coordinated care executed via an electronic health record (EHR)-based intervention on quality of care for gastroesophageal reflux disease…
- Trial name
- NCT00691171
- Volunteers
- 5,234 people
- Sponsor
- AstraZeneca
Diabetes Mellitus, Type 1, Gastroparesis
The Effect of Gluten-free Diet in Type 1 Diabetics With Dyspepsia Symptoms
Patients with type-1 diabetes are more susceptible to motility-related upper gastrointestinal symptoms. Dietary interventions are one of the treatment pillars for these symptoms.
- Conditions
- Diabetes Mellitus, Type 1, Gastroparesis, Dyspepsia, Gluten Sensitivity
- Trial name
- NCT03089632
- Testing
- Gluten-free diet
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- McMaster University
Achalasia, Esophageal, GERD (Gastroesophageal Reflux Disease)
Sling-Fiber Preservation POEM vs. Conventional POEM for Reducing Post-POEM GERD
Peroral endoscopic myotomy (POEM) is an effective, minimally invasive treatment for achalasia, offering excellent rates of symptom relief.
- Trial name
- SFP-POEM (NCT07178821)
- Testing
- Conventional POEM, Sling Fiber-Preserving POEM
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of California, Irvine
Flatulence, Constipation in Postnatal Women
Effects of Chewing Gum, Fennel, and Ginger Tea on Intestinal Motility and Comfort After Cesarean
This randomized controlled trial aims to evaluate the effects of chewing gum, fennel tea, and ginger tea consumption on intestinal motility and postpartum comfort in women following cesarean section.
- Trial name
- NCT07125742
- Testing
- Chewing gum, Fennel Tea, Ginger Tea
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Uşak University
Crohn's Disease, Inflammatory Bowel Disease
GI Symptoms and Sleep Disturbances in Patients With Quiescent Crohns Disease
In this study we would like to clarify the effect of long lasting Crohn's Disease on motility of the gastrointestinal system in patient and the effect regarding sleep disturbances.
- Conditions
- Crohn's Disease, Inflammatory Bowel Disease, Sleep Disturbances
- Trial name
- NCT02245594
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Gastrointestinal Motility Disorders
Safety and Efficacy Study of the FTRD System for Obtaining Full-thickness Intestinal Biopsies
The aim of this study is to evaluate FTRD (full-thickness resection device) in terms of obtaining full-thickness biopsies form the gastrointestinal tract endoscopically in the work-up of patients with gastrointestinal motility…
- Trial name
- NCT02673983
- Testing
- Endoscopic full-thickness biopsy
- Sponsor
- Region Skane
Cesarean Section, Gum Chewing
Role of Gum Chewing in Post-operative Gut Motility After Cesarean Section
Many women deliver by caesarean section nowadays. The proportion of women who deliver by caesarean section ranges from 15% to over 50%, in some countries.
- Conditions
- Cesarean Section, Gum Chewing, Gut Motility
- Trial name
- NCT06952985
- Testing
- Sugar free chew gum, Nil Per Oral
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr Maryam Aslam
Neurogenic Bowel Dysfunction
Stimulation for Colonic Motility
The investigators are testing the effect of electrical stimulation of the rectum on colonic motility. Most individuals with spinal cord injury develop neurogenic bowel dysfunction, which includes slowed colonic motility, which…
- Trial name
- NCT02641483
- Testing
- Electrical Rectal Stimulation
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- VA Office of Research and Development