Clinical trials: Intestinal Neoplasm, open to volunteers
Ampulla of Vater Carcinoma, Appendix Carcinoma
Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays
This clinical trial is being done to learn whether using the proactive, graduated dose modification algorithm for leucovorin, 5-fluorouracil (5-FU), and oxaliplatin (FOLFOX) (PAGODA) algorithm to guide chemotherapy dosing for the…
- Conditions
- Ampulla of Vater Carcinoma, Appendix Carcinoma, Carcinoma of Unknown Primary With Gastrointestinal Profile, Colon Carcinoma
- Trial name
- NCT07283939
- Testing
- PAGODA algorithm, Oxaliplatin, Folinic Acid
- Where
- 398 sites in United States, Guam and 1 more
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Alliance for Clinical Trials in Oncology
Functional Dyspepsia, Gastritis
The Prevalence and the Pathophysiological Role of Non-Helicobacter Pylori Helicobacter Spp. in Well-defined Gastric Diseases and (Pre-) Malignancies
The goal of this clinical trial is to discover the prevalence of NHPH bacteria (Non-Helicobacter pylori Helicobacter species) in patients with one of the following conditions: 1.
- Conditions
- Functional Dyspepsia, Gastritis, Gastritis Chronic, Gastric Cancer (GC)
- Trial name
- HELIS (NCT07770126)
- Where
- 3 sites in Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Gastric Cancer (GC), Premalignant Lesion
AI-Based Risk Prediction Model for Upper Digestive Tract Cancer
Upper digestive tract cancers are often preceded by pre-malignant lesions, but there is limited evidence regarding optimal risk prediction models and screening strategies for disease progression and cancer development.
- Conditions
- Gastric Cancer (GC), Premalignant Lesion, Gastric Intestinal Metaplasia, Atrophic Gastritis
- Trial name
- NCT07605312
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Gastric Atrophy, Gastric Intestinal Metaplasia
A Study Collecting Health Information to Understand and Prevent Gastric Cancer
The purpose of this study is to create a registry of participants with precursor lesions for gastric cancer, including gastric atrophy, intestinal metaplasia, and dysplasia.
- Conditions
- Gastric Atrophy, Gastric Intestinal Metaplasia, Dysplasia, Gastric Adenocarcinoma
- Trial name
- NCT06370143
- Testing
- Questionnaire
- Where
- 7 sites in United States
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer, Bowel Cancer
EQUITA - A Feasibility Trial of a Faith-placed Intervention to Increase Screening Uptake in Black Adults
The goal of this randomised feasibility trial is to examine feasibility and acceptability of a co-produced and faith-placed intervention to increase uptake of breast, cervical, bowel, and abdominal aortic aneurysm (AAA) screening…
- Conditions
- Breast Cancer, Bowel Cancer, Cervical Cancer, Abdominal Aortic Aneurysm
- Trial name
- EQUITA (NCT06981182)
- Testing
- Faith-placed intervention to promote breast, cervical, bowel, and AAA screening uptake in Black communities.
- Where
- 3 sites in United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Sunderland
Colorectal Cancer, Small Intestinal Bacterial Overgrowth Syndrome (SIBO)
Urine Metabolites in the Diagnosis of Disease
The goal of this observational study is to validate a non-invasive, urine-based diagnostic technology for the detection and differentiation of various gastrointestinal (GI) diseases.
- Conditions
- Colorectal Cancer, Small Intestinal Bacterial Overgrowth Syndrome (SIBO), Crohn Disease, Celiac Disease
- Trial name
- NCT06710067
- Where
- 4 sites in United States
- Volunteers
- 1,250 people, healthy volunteers welcome
- Sponsor
- Luventix, Inc.
Oncology, Hematologic Malignancy
AUD Biomarkers Study (Proteomic and Genomic Analysis of Biospecimens)
Study purpose: to explore the entire spectrum of proteomic and genomic changes (amongst others) involved in diseases and in healthy/control populations.
- Conditions
- Oncology, Hematologic Malignancy, Gastro-Intestinal Disorder, Autoimmune Diseases
- Trial name
- NCT05889806
- Testing
- Observational Study Only. NO Intervention.
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Audubon Bioscience
Gastric Cancer, Gastric Intestinal Metaplasia
Surveillance of Patients With Precancerous Lesions of the Stomach
The project will aim to identify and determine subgroups of patients with different risks of progression to gastric cancer and to assess appropriate follow-up intervals.
- Conditions
- Gastric Cancer, Gastric Intestinal Metaplasia, Gastric Atrophy, Gastric Dysplasia
- Trial name
- NCT03250091
- Testing
- Upper endoscopy with biopsies, Plasma/serum sampling, Biopsies for gastric microbiota
- Where
- Latvia
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Latvia