Clinical trials: Intestinal Obstruction, active
Hemorrhoids
Evaluation of the Analgesic Efficacy of an Ultrasound-guided Transperineal Pudendal Block in Outpatient Hemorrhoidal Surgery
In a population of patients undergoing hemorrhoidal surgery under general anesthesia and divided into two equal groups based on the method used for intraoperative pudendal nerve block and its branches in the ischioanal fossa…
- Trial name
- BACH (NCT07015775)
- Testing
- Neurostimulation, Ultrasound
- Where
- France
- Volunteers
- 202 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Hemorrhoids
Ultrasound-guided Sacral Erector Spinae Plane Block as a Sole Anesthetic Technique Versus Saddle Block in Hemorrhoidectomy
Study interventions: The patients will be randomized into two equal groups, Group A and Group B. Group A: Patients will receive an Ultrasound guided sacral erector spinae plane block (SESPB) Group B: Patients will receive Saddle…
- Trial name
- NCT06969274
- Testing
- Ultrasound guided sacral erector spinae plane block (SESPB), Saddle block.
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Aortic Stenosis, Gut Microbiome
Impact of Transcatheter Aortic Valve Implantation (TAVI) on the Gut Microbiota in Patients With Aortic Valve Stenosis
This study investigates the impact of transcatheter aortic valve implantation (TAVI) on the composition and function of the gut microbiota in patients with severe aortic valve stenosis.
- Conditions
- Aortic Stenosis, Gut Microbiome, Gut Microbiota, TAVI
- Trial name
- GUT-TAVI (NCT07052071)
- Testing
- TAVI
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Hippocration General Hospital
Colorectal Cancer, Neoadjuvant Chemotherapy
Camrelizumab Combined With Neoadjuvant Chemotherapy After Stent Placement for Left-Sided Obstructive Colonic Cancer
Patients with obstruction are associated with worse oncologic outcomes compared with those having nonobstructive tumors. Conventionally, patients with malignant large bowel obstruction receive emergency surgery, with morbidity…
- Conditions
- Colorectal Cancer, Neoadjuvant Chemotherapy, Stent, Obstruction
- Trial name
- NACSOC-02 (NCT05202314)
- Testing
- Immunotherapy (Camrelizumab)
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Beijing Chao Yang Hospital
Superior Mesenteric Artery Syndrome
Ultrasound Evaluation of Superior Mesenteric Artery Measurements in a Healthy Pediatric Population
Multicenter, prospective, observational research project on children aged from 10 to 15 years old undergoing abdominal ultrasound examinations during routine clinical practice.
- Trial name
- NCT04515251
- Testing
- Ultrasound measurements
- Where
- 2 sites in Switzerland
- Volunteers
- 289 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Gastrointestinal Complication, Intestinal Obstruction
The Influence of Feeding Source on the Gut Microbiome and Time to Full Feeds in Neonates With Congenital Gastrointestinal Pathologies
This study explores the use of an exclusive human milk diet versus standard feeding practices to compare the influence on feeding outcomes and the gut bacteria in infants with intestinal differences.
- Conditions
- Gastrointestinal Complication, Intestinal Obstruction, Gastroschisis, Hirschsprung Disease
- Trial name
- NCT06072976
- Testing
- Standard of Care, Exclusive Human Milk
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Seattle Children's Hospital
Adhesive Small Bowel Obstruction
Optimizing Treatment of Adhesive Small Bowel Obstruction
Small bowel obstruction (SBO) is one of the most common causes of serious gastrointestinal disease in the US. Adhesion-related SBO (aSBO) is usually treated by the placement of a nasogastric tube (NGT) to decompress the stomach…
- Trial name
- NCT06182319
- Testing
- Gastrografin, Saline, SBO Treatment Without NG Tubes
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, Los Angeles
Acute Abdomen, Ileus
Rectus Sheath Catheters Following Midline Laparotomy
Rectus sheath catheters (RSC) are used for postoperative analgesia following midline laparotomies. Local anesthetics are applied to the posterior rectus sheath via the RSC.
- Conditions
- Acute Abdomen, Ileus, Colorectal Carcinoma
- Trial name
- NCT07099924
- Testing
- Ropivacaine 0.2%, Saline 0.9%
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Asklepios Kliniken Hamburg GmbH
Kidney Transplant, Familial Hypercholesterolaemia
Cardiovascular Risk in Children With Chronic Conditions Study
Children living with chronic health conditions face a higher risk of developing cardiovascular diseases than their peers, largely due to the accelerated aging of the heart and blood vessels.
- Conditions
- Kidney Transplant, Familial Hypercholesterolaemia, Type 1 Diabetes Mellitus (T1DM), Type 2 Diabetes Mellitus (T2DM)
- Trial name
- CR3C (NCT07086989)
- Where
- 3 sites in Hungary
- Volunteers
- 300 people
- Sponsor
- Semmelweis University
Pancreatic Cancer Non-resectable, Bile Duct Cancer
Treatment of Distal Malignant Biliary Obstruction by Uncovered, Partially Covered, or Fully Covered Metal Stents
The goal of this randomized controlled trial is to compare uncovered, partially covered, and fully covered self-expandable metal stents (SEMS) in the palliative treatment of distal malignant biliary obstruction in a Swedish…
- Conditions
- Pancreatic Cancer Non-resectable, Bile Duct Cancer, Papillary Carcinoma, Duodenal Cancer
- Trial name
- NCT06453590
- Testing
- Randomization to uncovered SEMS treating jaundice due to distal malignant biliary obstruction., Randomization to partially covered SEMS treating jaundice due to distal malignant biliary obstruction., Randomization to fully covered SEMS treating jaundice due to distal malignant biliary obstruction.
- Where
- 12 sites in Sweden
- Volunteers
- 450 people
- Sponsor
- Region Stockholm
Appendicitis, Postoperative Pain
Comparison of Outcome of Open Appendectomy With and Without Transversus Abdominis Plane (TAP) Block
This study is being conducted to compare two types of pain management techniques in patients undergoing open appendectomy (surgical removal of the appendix through a traditional incision).
- Trial name
- NCT06943456
- Testing
- Transversus Abdominis Plane (TAP) Block for Postoperative Pain Management, Standard Open Appendectomy with Postoperative Pain Management
- Volunteers
- 136 people
- Sponsor
- University of Health Sciences Lahore
Gastric Outlet Obstruction, Small Bowel Obstruction
GT Metabolic Magnet System in Adults With Gastrointestinal Disorders
Evaluate the performance and safety of the GT Metabolic Magnet System for the creation of side-to-side compression anastomosis in the stomach and/or small bowel in conditions requiring an anastomosis as part of the underlying…
- Conditions
- Gastric Outlet Obstruction, Small Bowel Obstruction, Superior Mesenteric Artery Syndrome
- Trial name
- NCT07317076
- Testing
- Magnet System
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- GT Metabolic Solutions, Inc.
Post-COVID-19 Condition, Ulcerative Colitis
Emerging Indications for Hyperbaric Oxygen Treatment
This study will evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) on treating emerging indications (i.e., conditions that have shown to potentially benefit from HBOT) using the Multicenter Registry for Hyperbaric…
- Conditions
- Post-COVID-19 Condition, Ulcerative Colitis, Crohn Disease, Calciphylaxis
- Trial name
- NCT07240649
- Testing
- Hyperbaric oxygen treatment (HBOT), 100% Oxygen
- Volunteers
- 100 people
- Sponsor
- Jay C. Buckey Jr.
Large Bowel Obstruction
International Multi-center Profile of Emergency Large-Bowel Obstruction Management and Outcomes
Mechanical large-bowel obstruction is a common and high-risk emergency surgical condition with substantial variation in diagnostic evaluation, operative timing, and management strategies across institutions and healthcare…
- Trial name
- IMPEL (NCT07458867)
- Volunteers
- 500 people
- Sponsor
- European Society for Trauma and Emergency Surgery
Adhesive Small Bowel Obstruction
Predictors of Laparoscopy Conversion in Adhesive Small Bowel Obstruction
The goal of this observational study is to reveal predictors of unsuccessfull laparoscopic intervention in adult patients with adhesive small bowel obstruction.
- Trial name
- NCT07350447
- Testing
- Laparoscopic adhesiolysis, Laparotomic adhesiolysis
- Where
- 7 sites in Russia
- Volunteers
- 170 people
- Sponsor
- Almazov National Medical Research Centre
Incarcerated Hernia, Appendicitis Acute
Prevention of Postoperative Hernias in Emergency Surgery
The aim of this observational study is to understand the risk factors and incidence of postoperative hernias among patients undergoing emergency surgery.
- Conditions
- Incarcerated Hernia, Appendicitis Acute, Cholecystitis, Acute, Ileus
- Trial name
- PROPHECY (NCT06815822)
- Where
- Poland
- Volunteers
- 500 people
- Sponsor
- Jan Kochanowski University
Small Bowel Obstruction
Contribution of Point of Care Ultrasound by the Emergency Physician to Rule Out the Small Bowel Obstruction: a Diagnostic, Multicenter Study
Small Bowel Obstruction (SBO) is a frequent pathology in the emergency department (ED). Diagnosis is currently based on abdominal CT scan (CT).
- Trial name
- OCCLUS-POCUS (NCT06803628)
- Testing
- Point of care ultrasound
- Where
- 18 sites in France
- Volunteers
- 667 people
- Sponsor
- Nantes University Hospital
Small Bowel Adhesion, Obstruction Bowel
Intestinal Obstruction Surgery. Acute Abdominal Pathology. №9:05/05/2026
Abstract and Study Objectives Adhesive small bowel obstruction (ASBO) is a common indication for surgical intervention. Intra-abdominal adhesions are the leading cause of small bowel obstruction, particularly in patients with a…
- Conditions
- Small Bowel Adhesion, Obstruction Bowel, Adhesiolysis, Laparoscopic Abdominal Surgeries
- Trial name
- AIO-S/AAP (NCT07905300)
- Testing
- surgical operation
- Where
- Kazakhstan
- Volunteers
- 1,500 people
- Sponsor
- Astana Medical University
Small Bowel Obstruction
Water-Soluble Contrast Induced Intestinal Stimulation for the Treatment of Small Bowel Obstruction: A Feasibility Study
Small bowel obstruction (SBO) is common yet, how to best manage it remains unknown. One approach is to administer water soluble oral contrast (WSC) and the obtain x-rays to determine how well the bowel is functioning.
- Trial name
- NCT07099300
- Testing
- Abdominal Radiography
- Volunteers
- 60 people
- Sponsor
- University of California, Los Angeles
Colon Cancer, Splenic Flexure Mobilization
Surgical Outcomes in Splenic Flexure Cancers: A Multicenter Comparison of Segmental vs. Extended Hemicolectomy (SPARROW Study)
SPARROW Study: Surgical Outcomes in Splenic Flexure Cancer Colonic cancers located at the splenic flexure where the transverse colon turns into the descending colon are uncommon and represent less than 10% of all colorectal…
- Conditions
- Colon Cancer, Splenic Flexure Mobilization, Right Hemicolectomy, Left Hemicolectomy
- Trial name
- SPARROW (NCT07289568)
- Testing
- Colectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Acibadem University