Clinical trials: Intestinal Obstruction and Ileus
Chronic Nasal Congestion, Lung Infection
Biomarker for Cystic Fibrosis
International, multicenter, observational, longitudinal study to identify biomarker/s for Cystic fibrosis and to explore the clinical robustness, specificity, and long-term variability of these biomarker/s
- Conditions
- Chronic Nasal Congestion, Lung Infection, Breathlessness, Clubbing Toes
- Trial name
- BioCyFi (NCT02710383)
- Where
- 5 sites in Albania, Georgia and 3 more
- Volunteers
- 54 people
- Sponsor
- CENTOGENE GmbH Rostock
Obstruction, Cancer
Intravenous Nutrition in Hospitalized Patients: Comparison of Two Oils
Intravenous nutrition is an important therapy for the recovery of many patients. It is indicated when the patients cannot take food by mouth or use their intestines for feeding.
- Conditions
- Obstruction, Cancer, Ileus, Malnutrition
- Trial name
- NCT01943409
- Testing
- Intralipid, ClinOleic
- Where
- Canada
- Volunteers
- 303 people
- Sponsor
- Johane Allard
Ostomy - Ileostomy or Colostomy, Canser
The Effect of Ostomy Care Education Applied With the Teach-Back Method to Ostomy-Opened Individuals on Self-Care Power, Ostomy Adjustment, and Anxiety
The aim of this study is to examine the effect of ostomy care education-delivered to patients who have undergone ostomy surgery using the Teach-back method on patients' self-care ability, ostomy compliance, and anxiety levels.
- Conditions
- Ostomy - Ileostomy or Colostomy, Canser, Ileus, Intestinal Cancer
- Trial name
- NCT07788079
- Testing
- TEACH BACK METHOD
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Saglik Bilimleri Universitesi
Cancer Debulking, Enlarged Uterus
Comparing Intrathecal Morphine and Intraoperative Lidocaine Infusion to Epidural Anesthesia With Postoperative PCA for Patients Undergoing Exploratory Laparotomy
To determine if opioid consumption postoperatively among patients undergoing non-emergent laparotomy by the gynecologic oncology service who receive intrathecal morphine with intraoperative lidocaine (IML) infusion are lower than…
- Conditions
- Cancer Debulking, Enlarged Uterus, Fibroid Uterus, Adnexal Mass
- Trial name
- NCT05017246
- Testing
- Bupivacaine, Morphine, Lidocaine
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Washington University School of Medicine
Bowel Ileus, Cesarean Section Complications
Effect of Chewing Gum and Drinking Fennel Tea
Aim: Postoperative ileus after cesarean section is a problem that significantly prolongs hospital stay and increases perioperative costs.
- Trial name
- NCT06403215
- Testing
- Chewing gum group, Fennel tea group, Chewing gum+Fennel tea group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Marmara University
Gum Chewing, Preoperative
Preoperative Chewing Gum on Anxiety and Postoperative Nausea and Vomiting, Gastrointestinal Function
The aim of this study was to investigate the effects of chewing gum before surgery on preoperative anxiety, postoperative gastrointestinal functions (time to first gas, time to first defecation, bowel sounds, abdominal…
- Conditions
- Gum Chewing, Preoperative, Anxiety, Postoperative Nausea and Vomiting
- Trial name
- NCT06603025
- Testing
- chewing gum
- Where
- Cyprus
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
PIPO
Role of ACTG2 Variants in Smooth Muscle Determination and Function in Pediatric Intestinal Pseudo-obstruction.
The primary objective of this study is to describe the transcriptional impact of R178, R257, R40 or A136 variants of the ACTG2 gene on iPS differentiation mechanisms up to organoids derived from PIPO patient samples versus those…
- Trial name
- SMOOTH-PIPO (NCT06687564)
- Testing
- Biopsy
- Where
- 3 sites in France
- Volunteers
- 4 people
- Sponsor
- University Hospital, Grenoble
Gynecologic Disease, Postoperative Ileus
Postoperative Chewing Gum and Gynecological Laparoscopic Surgery
The authors aimed to evaluate the effects of postoperative gum chewing on laparoscopic gynecological surgery, gastrointestinal function-intestinal mobility and early postoperative recovery.
- Conditions
- Gynecologic Disease, Postoperative Ileus, Paralytic Ileus
- Trial name
- NCT03884244
- Testing
- chewing gum
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Bowel Ileus, Flatus
Chewing Gum on Postoperative Ileus in Children
Traditional postoperative care has been challenged recently to improve and speedup recovery (including the return of bowel function) such that patients can be discharged to home more quickly.
- Trial name
- GUM_1 (NCT03666377)
- Testing
- Gum chewing
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Stomach Cancer
Effect of Mosapride Citrate on Gastrointestinal Motility After Laparoscopic Gastrectomy
"Mosapride citrate is a 5-hydroxytryptamine 4 receptor agonist, and is widely used as an agent to increase intestinal motility. Mosapride citrate has been demonstrated in in vitro and in vivo studies to increase both gastric and…
- Trial name
- NCT04493125
- Testing
- Mosapride citrate
- Where
- South Korea
- Volunteers
- 104 people
- Sponsor
- Gangnam Severance Hospital
Meconium Obstruction of Prematurity, Respiratory Distress Syndrome in Premature Infant
Risk Factors of Meconium Obstruction and Respiratory Distress Syndrome in Preterm Infants
Although the pathophysiology of meconium obstruction of prematurity (MOP) is not clear, it is known that the decrease of the intestinal peristalsis due to decreased intestinal perfusion during antenatal or perinatal period.
- Trial name
- NCT03513640
- Where
- South Korea
- Volunteers
- 48 people
- Sponsor
- Seoul National University Hospital
Stoma Ileostomy, Stoma Colostomy
Conventional Hand Sewn End-To-End Anastomosis Versus Side-To-Side Anastomosis for Stoma Reversal: A Prospective Study
The goal of this clinical trial is to compare approaches to enterostomy reversal by hand-sewn end-to-end anastomosis versus side-to-side anastomosis (sub-divided into hand-sewn side-to-side anastomosis and stapled side-to-side…
- Conditions
- Stoma Ileostomy, Stoma Colostomy, Anastomosis, Ileus
- Trial name
- NCT05753709
- Testing
- Hand sewn end-to-end anastomosis, Hand sewn side-to-side anastomosis, Stapled side-to-side anastomosis
- Where
- India
- Volunteers
- 38 people
- Sponsor
- Sawai Mansingh Medical College
Colon Cancer, Splenic Flexure Mobilization
Surgical Outcomes in Splenic Flexure Cancers: A Multicenter Comparison of Segmental vs. Extended Hemicolectomy (SPARROW Study)
SPARROW Study: Surgical Outcomes in Splenic Flexure Cancer Colonic cancers located at the splenic flexure where the transverse colon turns into the descending colon are uncommon and represent less than 10% of all colorectal…
- Conditions
- Colon Cancer, Splenic Flexure Mobilization, Right Hemicolectomy, Left Hemicolectomy
- Trial name
- SPARROW (NCT07289568)
- Testing
- Colectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Acibadem University
Meconium Ileus
Impact of Visceral Osteopathic Treatment on Meconium Evacuation in Preterm Infants
Timing of the first and last meconium stool is critical for oral feeding tolerance and proper gastrointestinal function. The time until premature infants pass their first meconium ranges from 1 hour to 27 days (median: 43 hours).
- Trial name
- NCT02140710
- Testing
- Osteopathic treatment
- Where
- Austria
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Severe Acute Pancreatitis, Intra-abdominal Hypertension
Efficacy and Safety of Da-Cheng-Qi Decoction in Severe Acute Pancreatitis
This single-center prospective randomized controlled trial evaluated Da-Cheng-Qi Decoction (DCQD) as the acute-stage intervention of an integrated traditional Chinese and Western medicine whole-stage treatment protocol for severe…
- Trial name
- NCT07816900
- Testing
- Da-Cheng-Qi Decoction Plus Standard Western Treatment, Standard Western Treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Irritable Bowel Syndrome
Efficacy, Safety, and Tolerability of JNJ-27018966 (Eluxadoline) in the Treatment of Irritable Bowel Syndrome With Diarrhea
The purpose of this study is to determine the efficacy, safety, and tolerability of different doses of JNJ-27018966 (eluxadoline) compared with placebo in the treatment of patients with irritable bowel syndrome with diarrhea…
- Trial name
- NCT01130272
- Testing
- Eluxadoline
- Where
- 288 sites in United States
- Volunteers
- 807 people
- Sponsor
- Furiex Pharmaceuticals, Inc
Ileus; Mechanical, Contrast-induced Nephropathy
Investigation of Relationship Between Contrast Nephropathy and Caval Index Measurement in Patients With Ileus in ED
In this study, the investigators aimed to evaluate the incidence of vena cava inferior diamater on ultrasound guidance of intravascular volume before diagnosis of contrast enhanced CT for diagnostic purposes in ileus patients and…
- Trial name
- NCT03261518
- Testing
- inferior vena cava ultrasound
- Volunteers
- 250 people
- Sponsor
- Derince Training and Research Hospital
Intestinal Obstruction and Ileus, Perforated Viscus
Preoperative High-dose Dexamethasone and Emergency Laparotomy
The aim of this trial is to evaluate the effect of high-dose glucocorticoid on inflammatory response and recovery after emergency laparotomy in participants with intestinal obstruction and perforated viscus.
- Conditions
- Intestinal Obstruction and Ileus, Perforated Viscus, Sepsis, Pathophysiology
- Trial name
- NCT04791566
- Testing
- Dexamethasone 1 mg/kg, Physiologic saline
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Mirjana Cihoric
Fracture of Hip, Ileus
Peripheral Perfusion Index, Haemoglobin and Blood Transfusion in Acute Surgical Patients
The peripheral perfusion index (PPI) is a non-invasive, feasible measure of peripheral perfusion and, assumed, the overall circulation, which all patients are monitored by.
- Conditions
- Fracture of Hip, Ileus, Perforated Viscus, Anastomotic Leak
- Trial name
- NCT03795467
- Where
- Denmark
- Volunteers
- 1,500 people
- Sponsor
- Hvidovre University Hospital
Constipation, Ileus
Study About Effect of Preoperative Bowel Preparation Versus no Bowel Preparation Before Spinal Surgery
This study investigated the effect of preoperative bowel preparations for patients undergoing spinal fusion surgery.
- Conditions
- Constipation, Ileus, Surgery
- Trial name
- NCT01879605
- Testing
- Docusate natrium and sorbitol, Bisacodyl
- Where
- Norway
- Volunteers
- 45 people
- Sponsor
- Oslo University Hospital