Clinical trials: Intestinal Transplant
Graft Versus Host Disease, Postbiotics
Intestinal Microbiome-based Research for the Prevention of Acute GVHD
Hematopoietic stem cell transplantation consists of preconditioning chemotherapy, stem cell infusion, and engraftment of hematopoietic stem cells.
- Conditions
- Graft Versus Host Disease, Postbiotics, Butyrate
- Trial name
- NCT05808985
- Testing
- sodium butyrate
- Where
- South Korea
- Volunteers
- 15 people
- Sponsor
- Soonchunhyang University Hospital
Colorectal Cancer, Liver Metastases
Liver Transplantation for Non-resectable Colorectal Liver Metastases: Translational Research
The patients with non-resectable colorectal liver metastases (CRLM) have always being considered a particular subgroup of CRLM in which the therapeutic approach, is focused on strategies that allow a potential surgery like…
- Conditions
- Colorectal Cancer, Liver Metastases, Genetic Change
- Trial name
- NCT05398380
- Testing
- Liver transplantation
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- Hospital Vall d'Hebron
Crohn's Disease
Transplantation of Bone Marrow Mesenchymal Stem Cell in Crohn's Disease
This study is a prospective, randomized, parallel, phase 1 trial to assess the safety and feasibility of the transplantation of bone marrow derived mesenchymal stem cells (MSCs) in fistulizing Crohn's disease.
- Trial name
- NCT01874015
- Testing
- mesenchymal cell transplantation, mesenchymal cell and fibroblast injection
- Where
- Iran
- Volunteers
- 10 people
- Sponsor
- Royan Institute
Transplantation
Prospective Study of Drug Resistant Pathogens Among Liver, Intestinal and Multivisceral Transplant Recipients
Infections caused by multidrug resistant bacteria have become more prevalent at many tertiary care and academic centers. These infections are associated with increased morbidity and mortality.
- Trial name
- NCT00235664
- Testing
- Collection of stool and endotracheal aspirate samples
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Pittsburgh
Inflammatory Bowel Diseases, Fecal Microbiota Transplantation
Clinical Response and Safety Following FMT for UC
The study aims to evaluate the clinical efficacy and safety of fecal microbiota transplantation by automatic methods in the treatment of moderate to severe active ulcerative colitis.
- Trial name
- NCT04294615
- Testing
- FMT through a naso-jejunal tube, FMT through TET
- Volunteers
- 9 people
- Sponsor
- Air Force Military Medical University, China
Fecal Incontinence
Fecal Microbial Transplantation for the Treatment of Fecal Incontinence in Women
Open label pilot study assessing FMT to treat fecal incontinence in women 50 years of age and older.
- Trial name
- FMT for FI (NCT04201821)
- Testing
- fecal microbial transplantation (FMT)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Pennsylvania
Fecal Incontinence
Fat Grafting Technique for Fecal Incontinence
Fecal Incontinence affects an estimated 2-20% of the general population, and up to 50% of the elderly and institutionalized population.
- Trial name
- NCT03882632
- Testing
- Fat Grafting for Fecal Incontinence
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Melanie Salerno, RN
Acute Myeloid Leukemia, Graft-versus-host-disease
Changes in the Gut Microbiota of Patients Undergoing Allogeneic Stem Cell Transplantation (COLLECT)
COLLECT is a monocentric, prospective, observational study, which aims to assess the association between changes in the intestinal microbiota and the incidence of gastrointestinal graft-versus-host diseases (GvHD).
- Conditions
- Acute Myeloid Leukemia, Graft-versus-host-disease, Allogeneic Hematopoietic Stem Cell Transplantation, Stem Cell Transplant Complications
- Trial name
- COLLECT (NCT03148197)
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- University of Cologne
Chronic Myeloproliferative Disorders, Graft Versus Host Disease
Stem Cell Transplantation in Treating Patients With Hematologic Cancer
RATIONALE: Peripheral stem cell transplantation may be able to replace immune cells that were destroyed by chemotherapy and radiation therapy used to kill tumor cells.
- Conditions
- Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma
- Trial name
- NCT00004904
- Testing
- anti-thymocyte globulin, filgrastim, cladribine
- Where
- United States
- Sponsor
- Northwestern University
Acute Myeloid Leukemia With FLT3/ITD Mutation, Allogeneic Hematopoietic Stem Cell Transplantation
The Gut Microbiome and Sorafenib Maintenance Therapy in FLT3-ITD Positive AML After Allo-HSCT
This prospective trial investigates the effect of sorafenib maintenance therapy in FLT3-ITD positive AML patients after allo-HSCT in terms of gut microbiome.
- Trial name
- NCT05596968
- Testing
- Sorafenib
- Where
- China
- Volunteers
- 37 people
- Sponsor
- Nanfang Hospital, Southern Medical University