Clinical trials: Intra Abdominal Pressure
Ventral Hernia, Incisional Hernia
The Impact of Abdominal Wall Reconstruction on Abdominal Wall Tension and Intra-Abdominal Pressure
This is a prospective cohort study. Patients have an incisional or parastomal hernia with >20 cm fascial defect on pre-operative imaging who will undergo an anticipated open bilateral transversus abdominis release with…
- Conditions
- Ventral Hernia, Incisional Hernia, Parastomal Hernia
- Trial name
- NCT06575166
- Testing
- Abdominal wall tension, Intra-abdominal pressure
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Postpartum Period, Pelvic Floor Disorders
Therapeutic Exercise for Postpartum Recovery
Pelvic floor dysfunctions (PFDs) are common conditions that affect women, especially after vaginal childbirth. These disorders can cause urinary or fecal incontinence, pain during sexual activity, and prolapse of pelvic organs…
- Trial name
- PelviRecover (NCT07313683)
- Testing
- Therapeutic Education (TE), Pelvic Floor Exercises (PFMT), Lumbopelvic Stabilization Exercises (LSE)
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- University of Alcala
Laparoscopic Surgery
Predictive Variables of the Hemodynamic Effect During the Laparoscopic Surgery in Children
This prospective observational study aimed to identify the intraoperative variables to predict the hemodynamic change according to intra-abdominal pressure in the children undergoing laparoscopic surgery.
- Trial name
- Lapa-BP (NCT02536521)
- Where
- South Korea
- Volunteers
- 123 people
- Sponsor
- Seoul National University Hospital
Critically Ill, Liver Cirrhosis
The Influence of Paracentesis on Intra-abdominal Pressure and Kidney Function in Critically Ill Patients With Liver Cirrhosis and Ascites: an Observational Study
Patients with liver cirrhosis are at risk for development of renal failure, usually after a precipitating event such as infection or bleeding.
- Conditions
- Critically Ill, Liver Cirrhosis, Ascites
- Trial name
- NCT01091233
- Testing
- paracentesis
- Where
- Belgium
- Sponsor
- University Hospital, Ghent
Hernia, Ventral, Hernia Incisional
Renal- and Pulmonary Function in Relation to Abdominal Hypertension After Abdominal Reconstruction
An incisional hernia is technically challenging to operate and is the most frequent long-term complication after open surgery, resulting in impaired quality of life and reduced physical ability.
- Conditions
- Hernia, Ventral, Hernia Incisional, Acute Kidney Injury, Restrictive Lung Disease
- Trial name
- REPARE (NCT04143776)
- Testing
- Abdominal reconstruction
- Where
- Denmark
- Sponsor
- Bispebjerg Hospital
Intra Abdominal Pressure, Abdominal Compartment Syndrome
Intra-abdominal Hypertension and Abdominal Compartment Syndrome in Patients After Pancreatic Procedures.
This study investigates the development of intra-abdominal hypertension and compartment syndrome in patients undergoing elective pancreatic procedures.
- Conditions
- Intra Abdominal Pressure, Abdominal Compartment Syndrome, Pancreatic Surgery, Pancreatic Fistula After Pancreaticoduodenectomy
- Trial name
- HYPA (NCT06672601)
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- Charles University, Czech Republic
Peritoneal Dialysis
Intra-abdominal Pressure in Peritoneal Dialysis Patients
Patients treated with peritoneal dialysis (PD) are at increased risk of developing mechanical complications such as dialysate leaks and hernias thought to be related to an increase in intra-abdominal pressure (IAP) secondary to…
- Trial name
- NCT02811640
- Testing
- Study Participants
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Ottawa Hospital Research Institute
Acute Kidney Injury, Intra-Abdominal Hypertension
Cumulative Intra-Abdominal Pressure Burden and Acute Kidney Injury After Emergency Abdominal Surgery
The goal of this observational study is to learn whether increased pressure inside the abdomen over time is associated with acute kidney injury in adults receiving intensive care after emergency abdominal surgery.
- Trial name
- IAP-AKI (NCT07891026)
- Testing
- Serial Intra-Abdominal Pressure Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Ugur Duman
Intra-Abdominal Hypertension, Postoperative Complications
The Impact of Intra-Abdominal Pressure on Mortality and Morbidity in Patients Undergoing Open-Heart Surgery
This prospective observational study evaluated whether increased intra-abdominal pressure, meaning increased pressure inside the abdomen, is associated with postoperative complications and mortality in adults undergoing elective…
- Trial name
- NCT07752082
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Urinary Catheter, Laparoscopic Surgery
Validation of Serenno CUO and IAP Measuring Device
Serenno Medical Automatic Urine Output measuring device is intended to measure volumetric flow rate (total volume and rate) of urine produced per minute over long periods by a patient with a urinary catheter as well as high…
- Trial name
- NCT05121454
- Testing
- Serenno Sentinel, model Alpha 2.0, software version: 8.0
- Where
- Israel
- Volunteers
- 31 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Pseudomyxoma Peritonei, Colorectal Cancer
HIPEC Using High Intra-abdominal Pressure
Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) is a promising therapy for peritoneal carcinomatosis (PC) of various origins.
- Trial name
- HIPEC-IAP (NCT02949791)
- Testing
- Cytoreductive surgery, Low Intra abdominal pressure HIPEC, High Intra abdominal pressure HIPEC
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Intra-Abdominal Hypertension
First-In-Human Study of PDT to Detect IAH
PDT is a continuous pressure monitoring for Intra-Abdominal hypertension (IAH) designed to be less invasive than pan-endoscopic evaluation, more tolerable than abdominal tapping, and more effective than intravesical pressure…
- Trial name
- NCT06333366
- Testing
- Intra-gastrointestinal monitoring device (PDT)
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- Chang Gung Memorial Hospital
Septic Shock, Septicemia
Efficacy of Targeted Abdominal Perfusion Pressure in Septic Shock
Septic shock is a clinical condition that is defined as a subset of sepsis that causes very high mortality and morbidity. Surviving sepsis campaign guideline states that the target mean arterial pressure should be 65 mmHg and…
- Conditions
- Septic Shock, Septicemia, Intraabdominal Hypertension, Renal Injury
- Trial name
- NCT05358912
- Testing
- Vasopressor Agent, Crystalloid Solutions, Invasive Blood Pressure Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Bozyaka Training and Research Hospital
Citrulline, Organ Failure, Multiple
INtestinal Failure, multiPle Organ Failure ANd CItrulline Assessment
The gastrointestinal dysfunction occurs frequently during the intensive care unit (ICU) stay and is associated with a worse prognosis.
- Conditions
- Citrulline, Organ Failure, Multiple, Gastro Intestinal Failure, Intra Abdominal Pressure
- Trial name
- IN-PANCIA (NCT02520440)
- Testing
- Monitoring of plasmatic levels of Citrulline, Intra-abdominal pressure monitoring, Monitoring of plasmatic levels of Arginine and Glutamine
- Volunteers
- 42 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Obesity, Intra-Abdominal Hypertension
Chest Wall Influence on Respiratory System Mechanics in Morbidly Obese Patients
The goal of this study is to describe the influence of the chest wall on the respiratory system mechanics in morbidly obese patients and in patients with high intra-abdominal pressure.
- Trial name
- NCT02105220
- Testing
- Respiratory mechanics assessment
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Massachusetts General Hospital
Septic Peritonitis
Effects of Dexmedetomidine vs Propofol in Patients With Intra-abdominal Sepsis
Sepsis is defined as systemic response to infection ,and it is a main problem in ICU and despite advance in supportive care, the mortality rate in patients with severe sepsis continues to exceed 30% [Bone RC 1993].The effects of…
- Trial name
- NCT04718714
- Testing
- Midazolam, Propofol, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Increased Intracranial Pressure Disorders, Perioperative Complication
Optic Nerve Sheath Diameter Changes in Laparoscopic Cholecystectomy
Purpose The goal of this clinical trial is to learn how different intra-abdominal pressures during laparoscopic cholecystectomy affect the optic nerve sheath diameter (ONSD), which is a non-invasive marker of intracranial…
- Conditions
- Increased Intracranial Pressure Disorders, Perioperative Complication, Pneumoperitoneum
- Trial name
- NCT07162922
- Testing
- 8 mmHg pressure group, 14 mmHg pressure group
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Engin Çetin
Lumbar Spine Fusion
Early Initiation of a Strength Training Based Rehabilitation After Lumbar Spine Fusion Improves Core Muscle Strength
To analyze safety and the effects of early initiation of the rehabilitation. Including the objective measurement outcomes after lumbar spine fusion, based on the principles of strength training.
- Trial name
- NCT03349580
- Testing
- The training group
- Volunteers
- 27 people
- Sponsor
- Dejan Kernc
Acute Pancreatitis, Intra-Abdominal Hypertension
Predictive Ability of Intra-Abdominal Pressure for Mortality in Patients With Severe Acute Pancreatitis
Severe Acute Pancreatitis (SAP) is an acute inflammatory condition of the pancreas characterized by organ dysfunction and increased mortality.
- Trial name
- NCT04525027
- Testing
- intra-abdominal pressure in severe acute pancreatitis
- Where
- India
- Volunteers
- 360 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Obesity, Intra-Abdominal Fat
Effect of a Probiotic on Visceral Fat Accumulation
The study's main objective is to investigate if an extract containing the probiotic Bifidobacterium animalis subsp. lactis BPL1 (CECT 8145) has a positive effect on the accumulation of abdominal visceral fat in people with…
- Conditions
- Obesity, Intra-Abdominal Fat, Subcutaneous Fat, Abdominal
- Trial name
- BIFFAT (NCT02921217)
- Testing
- Active Probiotic, Inactivated probiotic, Control
- Where
- Spain
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Biopolis S.L.