Clinical trials: Intra-Abdominal Abscess
Abdominal Abscess
Abdominal aBscess Catheter Sclerotherapy (ABCS)
This is a single center, two arm phase I/II clinical trial exploring the use of chemical sclerosants (ethanol and povidone iodine) in decreasing the time needed for catheter drainage for patients with non-fistulous intraabdominal…
- Trial name
- ABCS (NCT06906029)
- Testing
- Catheter Sclerotherapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Appendicitis, Cholecystitis
Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection (cIAI)
This is a study of the safety and efficacy of tigecycline to ceftriaxone sodium plus metronidazole in hospitalized subjects with cIAI. Subjects will be followed for efficacy through the test-of-cure assessment.
- Conditions
- Appendicitis, Cholecystitis, Diverticulitis, Intra-Abdominal Abscess
- Trial name
- NCT00230971
- Testing
- tigecycline, ceftriaxone plus metronidazole
- Where
- 68 sites in Australia, China and 17 more
- Volunteers
- 473 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Liver Abscess, Pyogenic, Liver Abscess
An Observational Study of Risk Factors and Long-term Prognosis of Patients With Liver Abscess in the "Real-world"
Pyogenic liver abscess is one of the most common visceral abscesses, its incidence is increasing worldwide. According to the previous literature, the mortality rate of pyogenic liver abscess is as high as 31% and become a serious…
- Conditions
- Liver Abscess, Pyogenic, Liver Abscess, Abscess, Infections
- Trial name
- NCT05213949
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Abdominal Abscess
Antibiotic Irrigations for Intra-Abdominal Drains
Intra-abdominal abscesses are pus-filled pouches in the abdominal cavity. Current standard of care includes drain placement in the abscess cavity to reach source control as well as administration of systemic antibiotics.
- Trial name
- AID (NCT03476941)
- Testing
- Gentamicin Sulfate Inj 20mg/2ml vial for injection, Clindamycin phosphate 6 mg/1ml for injection
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Appendicitis, Abdominal Abscess
Irrigation Versus Suction in Complicated Acute Appendicitis
This study evaluates the intraabdominal abscess rate after laparoscopic appendectomy in complicated acute appendicitis performing irrigation of the abdominal cavity or only suction without lavage.
- Conditions
- Appendicitis, Abdominal Abscess, Acute Disease, Cecal Diseases
- Trial name
- ISAAC (NCT02688244)
- Testing
- Irrigation, No irrigation
- Where
- Spain
- Volunteers
- 210 people
- Sponsor
- Hospital Universitario Virgen de la Arrixaca
Liver Abscess, Pyogenic
Antibiotics for Klebsiella Liver Abscess Study
Background: Klebsiella pneumoniae liver abscess is the most common etiology of liver abscess in Singapore and much of Asia, and its incidence is increasing.
- Trial name
- NCT01723150
- Testing
- Ciprofloxacin, Ceftriaxone, Trimethoprim/sulfamethoxazole
- Where
- 3 sites in Singapore
- Volunteers
- 152 people
- Sponsor
- National University Hospital, Singapore
Crohn's Disease
Exclusive Enteral Nutrition Therapy for Active and Complicated Crohn's Disease
The goal of this observational study is to evaluate the effectiveness and safety of exclusive enteral nutrition (EEN) in adults with active Crohn's disease (CD), particularly in patients with complicated disease such as…
- Trial name
- EEN-CD (NCT07504510)
- Testing
- Exclusive Enteral Nutrition
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Pancreaticoduodenectomy, Distal Pancreatectomy
Randomized Trial of Early Versus Standard Drainage Removal After Pancreatic Resections
Despite a substantial decrease in postoperative mortality, morbidity after pancreatic resections is still high, even at high-volume centers.
- Conditions
- Pancreaticoduodenectomy, Distal Pancreatectomy, Pancreatic Fistula, Abdominal Abscess
- Trial name
- NCT00931554
- Testing
- Postoperative drain removal
- Where
- Italy
- Volunteers
- 114 people
- Sponsor
- Universita di Verona
Secondary Peritonitis, Abscess, Intra-Abdominal
Moxifloxacin i.v. in the Treatment of Complicated Intra-Abdominal Infection (cIAI)
This study is a local, prospective, open-label, company-sponsored, non interventional, multi-center study. Patients documented must suffer from a cIAI and take at least one dose of Moxifloxacin infusion.The primary objective is…
- Trial name
- NCT01096511
- Testing
- Moxifloxacin (Avelox, BAY12-8039)
- Where
- China
- Volunteers
- 1,001 people
- Sponsor
- Bayer
Acute, Perforated Appendicitis
Povidone-iodine Irrigation for Prevention of Intra-abdominal Abscess in Pediatric Perforated Appendicitis: a Multi-center Stepped Wedge Cluster Randomized Study
The purpose of this study is to determine the effect of intra-abdominal irrigation with povidone-iodine (PVI) versus usual care on the rate of 30-day postoperative intra-abdominal abscesses (IAA) and to determine the effect of…
- Trial name
- PAPPA (NCT04200729)
- Testing
- Irrigation with PVI, Usual care
- Where
- United States
- Volunteers
- 1,750 people
- Sponsor
- The University of Texas Health Science Center, Houston
Perforated Appendicitis
APPI-Cost Trial for Perforated Appendicitis
The purpose of this study to assess the clinical effectiveness and cost-effectiveness of povidone-iodine (PVI) irrigation in perforated appendicitis, to investigate barriers and facilitators to future implementation of PVI…
- Trial name
- NCT06705842
- Testing
- PVI, Usual Care
- Where
- United States
- Volunteers
- 346 people
- Sponsor
- The University of Texas Health Science Center, Houston
Autoimmune Hepatitis, Primary Sclerosing Cholangitis
Liver-gut Axis Study Through Identification of Liver Disease-specific Microbiome
In this study, we aim to identify gut microbiomes specific to patients with chronic refractory liver disease and to conduct a gut-liver axis study on the pathogenesis and disease progression.
- Conditions
- Autoimmune Hepatitis, Primary Sclerosing Cholangitis, Non-Alcoholic Fatty Liver Disease, Liver Abscess
- Trial name
- LGAS (NCT06519162)
- Where
- South Korea
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Chungnam National University Hospital
Peritoneal Contamination After Ileocolonic Anastomosis, Wound Infection
Microbiological Spectrum of the Intraperitoneal Surface After Elective Right-sided Colon Cancer
Despite performing colonic surgery with strict asepsia measures, minimizing the contact of the colon lumen with the peritoneum, some contamination is nearly impossible to avoid.
- Conditions
- Peritoneal Contamination After Ileocolonic Anastomosis, Wound Infection, Intra-abdominal Abscess
- Trial name
- NCT01458353
- Testing
- Stapled anastomosis, Handsewn anastomosis
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Hospital General Universitario Elche
TACE, HCC - Hepatocellular Carcinoma
Prediction and Prognostic Analysis of Liver Abscess Formation After Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma (CHANCE 2407)
Liver abscess is a rare but serious complication of hepatocellular carcinoma after TACE, with an incidence of less than 1% reported in previous literature.
- Conditions
- TACE, HCC - Hepatocellular Carcinoma, Liver Abscess
- Trial name
- NCT06483594
- Volunteers
- 400 people
- Sponsor
- Shengjing Hospital
Bowel Perforation, Abscess
Clinical Significance of Intra-abdominal Hypertension in Surgical Patients With Severe Sepsis
Intra-abdominal pressure(IAP) is defined as a steady state pressure of the abdominal cavity many studies have proved IAP as a prognostic factor that elevated IAP influences hemodynamics and multiple organs dysfunction In previous…
- Conditions
- Bowel Perforation, Abscess, Leakage, Peritonitis
- Trial name
- NCT01784458
- Volunteers
- 46 people
- Sponsor
- University of Ulsan
Intraabdominal Abscess After Procedure, Leakage
Outcome After Laparoscopic Surgery for Peptic Ulcer Perforation
Despite advances in laparoscopic surgery for perforated peptic ulcer (PPU), intra-abdominal abscess (IAA) is recognized as one of the commonly reported complications with relation to the extent of infectious abdominal…
- Conditions
- Intraabdominal Abscess After Procedure, Leakage, Pneumonia, Operation Wound; Infection
- Trial name
- NCT05147870
- Testing
- Peritoneal irrigation, Suction only
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Chang Wei-Jung