Clinical trials: Intra-abdominal Surgery
Complication, Anastomotic Leak
Prediction of Intra-abdominal Infectious Complication by Drainage Fluid Analysis
In our previous study, a nomogram model was established to predict intra-abdominal infectious complications after gastrointestinal surgery.
- Conditions
- Complication, Anastomotic Leak, Intraabdominal Infections, Inflammatory Response
- Trial name
- APPEAL-GC (NCT03862378)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University
Patients Undergoing Major Abdominal Surgery
Peri-operative Expression Analysis of Pancreatic Stone Protein in a Surgical Study Population
The purpose of this study is to analyze the peri-operative expression of pancreatic stone protein and pancreatitis-associated protein in surgical patients following major abdominal surgery by blood samples.
- Trial name
- NCT01258179
- Testing
- Analysis of PSP and PAP from venous blood samples
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University of Zurich
Blood Loss, Surgical
Evaluation of Fibrin Sealant 2 in Retroperitoneal or Intra-Abdominal Surgery
A comparison of fibrin sealant 2 versus Surgicel® as an addition to standard surgical practice in stopping mild to moderate soft tissue bleeding during retroperitoneal or intra-abdominal surgery.
- Trial name
- NCT00307515
- Testing
- Fibrin Sealant 2 (FS2), Oxidized Regenerated Cellulose (Surgicel)
- Where
- 16 sites in United States
- Volunteers
- 135 people
- Sponsor
- Ethicon, Inc.
Gynecologic Surgical Procedures
Comparing Intra-Abdominal Pressure During Gynecologic Laparoscopy
The goal of this clinical trial is to learn if the level of intra-abdominal pressure during benign gynecologic laparoscopic surgery impacts postoperative pain.
- Trial name
- NCT07221487
- Testing
- abdominal pressure
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Nassau University Medical Center
Intra-abdominal Perforation
the Influence of Prophylactic and Empirical Anti-fungal Treatment in Severe Sepsis Patients With Perforations
This prospective intended to observe the influence of prophylactic and empirical anti-fungal treatment on Severe Sepsis patients with perforations.
- Trial name
- NCT02941068
- Testing
- fluconazole and caspofungin
- Volunteers
- 223 people
- Sponsor
- Nanjing PLA General Hospital
Cardiac Index
Effects of Neuromuscular Blockade Level and Intra-abdominal Pressure on Surgical Conditions and Cardiopulmonary Responses During Laparoscopic Colon Surgery With the Trendelenburg Position
The purpose of this study is to find out the effect of low abdominal pressure vs. standard abdominal pressure on the cardiac and respiratory function of the patients undergoing laparoscopic colon surgery in Trendelenberg…
- Trial name
- NCT02249585
- Testing
- Standard abdominal pressure, Low abdominal pressure, Conventional neuromuscular blockade
- Where
- South Korea
- Volunteers
- 131 people
- Sponsor
- Seoul National University Hospital
Sepsis
Persistent Inflammation, Immunosuppression and Catabolism Syndrome (PICS): A New Horizon for Surgical Critical Care and Induced Frailty
The purpose of this study is to define the natural history and causes of chronic critical illness (CCI) in surgical intensive care patients who have had sepsis.
- Trial name
- NCT02711709
- Testing
- Frailty Measurements, Modified Minnesota Leisure Time Activities, Computed tomography morphometrics
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- University of Florida
Surgery, Pancreatitis
Active Versus Non Active Drainage for the Treatment of Infected Intra-abdominal Collection
The Percutaneous drainage of symptomatic intra-abdominal collection (primary or secondary to surgery)is the treatment of choice in the absence of peritonitis signs.
- Conditions
- Surgery, Pancreatitis, Diverticulitis, Appendicitis
- Trial name
- NCT01513421
- Testing
- Percutaneous drainage of intra-abdominal collection
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Peritoneal Surface Malignancy, Postoperative Adhesion
SurgiPerito Trial: High-Purity Type-I Collagen for Peritoneal Reconstruction After Cytoreductive Surgery
This dual-centre, randomized controlled trial evaluates the safety and efficacy of high-purity Type-I collagen-based biomaterial, as a peritoneal substitute following peritonectomy in patients undergoing cytoreductive surgery…
- Conditions
- Peritoneal Surface Malignancy, Postoperative Adhesion, Bowel Obstruction, Wound Complications
- Trial name
- NCT07241091
- Testing
- High-Purity Type-I Collagen Scaffold, Standard Peritonectomy Closure
- Where
- 2 sites in India
- Volunteers
- 60 people
- Sponsor
- Adichunchanagiri Institute of Medical Sciences, B G Nagara
Ventral Hernia Repair
ORION Study: Mesh Position and Risk During Subsequent Minimally Invasive Abdominal Surgery
Ventral hernia repair is one of the most commonly performed abdominal surgical procedures worldwide, increasingly carried out using minimally invasive techniques.
- Trial name
- ORION (NCT07384962)
- Where
- Italy
- Volunteers
- 790 people
- Sponsor
- Istituto Auxologico Italiano
Abdominal Aorta Aneurysm, Abdominal Aorta Atheroma
Impact of Intra- and Postoperative Continuous Infusion of Lidocaine on Analgesia in Vascular Anaesthesia
The aim of the study is to test the effectiveness and safety of the use of lidocaine infusion in multimodal analgesic management.
- Conditions
- Abdominal Aorta Aneurysm, Abdominal Aorta Atheroma, Surgery, Pain, Postoperative
- Trial name
- NCT04691726
- Testing
- lidocaine 10mg/ml, Metamizole, Morphine
- Where
- Poland
- Volunteers
- 87 people
- Sponsor
- Łukasz Krzych
Morbid Obesity, Acidosis
Intraoperative Fluid Management in Laparoscopic Bariatric Surgery
The objective of this study is to evaluate the effects of 'high' versus 'low' volume intraoperative fluid administration (Ringer Lactate, RL) on intra- and postoperative parameters, in obese patients undergoing laparoscopic…
- Conditions
- Morbid Obesity, Acidosis, Intra-Abdominal Abscess, Hemorrhage
- Trial name
- NCT00905502
- Testing
- Lactated Ringer's solution
- Where
- Israel
- Volunteers
- 107 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Hemoperitoneum, Ascites
Free Fluid Detection With Telementored eFAST
This feasibility study will evaluate the accuracy of telementored eFAST (Extended Focused Assessment with Sonography in Trauma) in detecting abdominal free fluid in patients who have recently undergone liver surgery.
- Conditions
- Hemoperitoneum, Ascites, Intra-Abdominal Fluid Collection, Postoperative Complications
- Trial name
- NCT06594562
- Testing
- Telementored eFAST
- Where
- Norway
- Volunteers
- 34 people
- Sponsor
- Oslo University Hospital
Laparoscopic Surgery, Pneumoperitoneum
The Effect of Intra-abdominal Pressure on Peritoneal Perfusion During Laparoscopic Colorectal Surgery
Peritoneal perfusion during laparoscopic surgery is quantified by video recording after intravenous injection of indocyanine green at a pneumoperitoneum pressure of 8, 12 and 16 mmHg.
- Trial name
- PERFUSION (NCT03928171)
- Testing
- Intra-abdominal pressure during laparoscopy
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Radboud University Medical Center
Acute Kidney Injury, Arterial Hypertension
Study Evaluating Novel Biomarkers of AKI (Acute Kidney Injury) in Post-operative Patients
To validate the use of [TIMP-2]●[IGFBP-7] to predict AKI in patients undergoing major intra abdominal surgery.
- Conditions
- Acute Kidney Injury, Arterial Hypertension, Obesity, Cardio Vascular Disease
- Trial name
- NCT02499185
- Testing
- Nephro Check Test, serum creatinine measurement
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Universitair Ziekenhuis Brussel
Postoperative Pulmonary Complications, Intra-abdominal Infection
The Effect of Continuous Intravenous Infusion of Lidocaine on PPCs and Prognosis in Emergency Surgical Patients With IAI
The main purpose of this study is to evaluate the impact of continuous 24-hour intravenous infusion of lidocaine on the incidence of PPCs in patients undergoing emergency laparotomy for intra-abdominal infection (IAI).The…
- Trial name
- PPCs (NCT06304779)
- Testing
- Lidocaine
- Where
- China
- Volunteers
- 428 people
- Sponsor
- Shanghai Zhongshan Hospital
Laparoscopic Cholecystectomy Surgery, Analgeisa
Pain Relief Following Laparoscopic Cholecystectomy While Comparing Intra Abdominal Versus Sub Cutaneous Local Anesthetic Administration
Laparoscopic cholecystectomy involves removal of gallbladder through small incision ports resulting in faster recovery. Small incisions are less painful and hence local anesthesis administered can be effective for pain…
- Conditions
- Laparoscopic Cholecystectomy Surgery, Analgeisa, Local Anesthetic Infiltration
- Trial name
- NCT07409688
- Testing
- Intraoperitoneal local anesthetic administration, Sub cutaneous administration of local anesthetic
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rawalpindi Medical College