Clinical trials: Intra-operative Anesthesia
Pain, Postoperative, Opioid Use
Spinal Anesthesia and Peri-operative Opioid Consumption in Open Abdominal Prostatectomy
Retrospective analysis to assess the impact of spinal anesthesia on peri-operative opioid consumption during open abdominal prostatectomy.
- Conditions
- Pain, Postoperative, Opioid Use, Analgesia
- Trial name
- SAPOC (NCT03565705)
- Testing
- Open abdominal prostatectomy
- Where
- Germany
- Volunteers
- 636 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Neurological Morbidity, Surgical Complication
The Implementation of the Classification of Intraoperative Adverse Events (ClassIntra) for Neurosurgical Procedures
In the planned study, the ClassIntra score will be assessed after all neurosurgical procedures in the upcoming 6 months and correlated with all pre- and postoperative data.
- Conditions
- Neurological Morbidity, Surgical Complication, Anesthesia Morbidity
- Trial name
- NCT04956835
- Where
- Germany
- Volunteers
- 750 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Monitoring, Physiologic, Intraoperative Neurophysiological Monitoring
Analyzing the Noxious Autonomic Response During Shoulder Arthroscope Surgery
To record the digital data from monitoring instruments (standard patient monitor) containing cardiovascular system information, and from depth-of-anesthesia monitoring modules (Bispectral index, Entropy module, Surgical…
- Conditions
- Monitoring, Physiologic, Intraoperative Neurophysiological Monitoring, Anesthesia and Analgesia, Arthroscopy
- Trial name
- NCT03688529
- Volunteers
- 40 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Anesthesia
Magnesium for Shivering in Epidural Lidocaine Deliveries
Magnesium has been shown to decrease the shivering experienced from neuraxial anesthesia. This study aims to investigate whether magnesium decreases the shivering experienced in parturients undergoing labor epidural anesthesia…
- Trial name
- Mag-SHIELD (NCT03439358)
- Testing
- Magnesium Sulfate, Normal Saline
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Arthritis, Degenerative
Intraoperative Sedatives and Postoperative Pain
In this study, based on the hypothesis that dexmedetomidine administered intraoperatively for sedation can reduce postoperative pain than that of propofol, the investigators examined the ability of dexmedetomidine to reduce…
- Trial name
- NCT02784626
- Testing
- Dexmedetomidine, Propofol
- Where
- South Korea
- Volunteers
- 48 people
- Sponsor
- Seoul National University Bundang Hospital
Intraoperative Awareness, Postoperative Pain
Role of Intraoperative Beta Blocker for Morbid Obese Patients Undergoing Laparoscopic Bariatric Surgery
Using esmolol during anesthetic maintenance of laparoscopic bariatric surgery significantly decreases anesthetic, analgesic requirements, postoperative pain, PNV and postoperative hypoxia.
- Trial name
- NCT04086940
- Testing
- Esmolol
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Breast Cancer, Breast Surgery
Hemodynamic Effects of Intradermal Methylene Blue During Breast Surgery Under General Anesthesia
This prospective observational study aims to evaluate the effects of intradermal methylene blue injection on intraoperative hemodynamic stability in patients undergoing breast surgery under general anesthesia.
- Conditions
- Breast Cancer, Breast Surgery, Sentinel Lymph Node Biopsy, Methylene Blue
- Trial name
- NCT07040540
- Testing
- Methylene Blue, Standard Surgical Care Without Dye
- Where
- Turkey (Türkiye)
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Intraoperative Bleeding
Comparison Between Atenolol,Propnalol and Ivabradine
The aim of this work is to compare atenolol, propranolol, and ivabradine as a premedication to achieve bloodless field anesthesia primarily controlling heart rate in lumbar spine surgery.
- Trial name
- NCT06670690
- Testing
- Atenolol 50 MG, Propranolol Pill, Ivabradine
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Postoperative Sore Throat, Cough, Hoarseness
Air Versus Lignocaine for Endotracheal Tube Cuff Inflation and Effect on Postoperative Sore Throat and Intracuff Pressure
Endotracheal Tube (ETT) is frequently used for GA (general anesthesia) to deliver oxygen and volatile anesthetic agents to the patient and serves as a channel for anesthetic gases.
- Trial name
- NCT07315490
- Testing
- Xylocaine
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- PAEC General Hospital, Islamabad
Burst Suppression, General Anesthesia
Interrater Variability for the Identification of Anesthetic-induced Burst Suppression EEG
Burst suppression describes a specific EEG pattern that can generally indicate a too deep general anesthesia. The pathophysiology of anesthetic-induced Burst Suppression may be distinctly different from the pathophysiology of…
- Conditions
- Burst Suppression, General Anesthesia, Electroencephalogram
- Trial name
- NCT05508386
- Testing
- MATLAB-based interface, showing 50 EEG traces, classification of the EEG-pattern as Burst Suppression possible, yes, no.
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Breast Reconstruction
The Effect of Intraoperative Binaural Beats on Remimazolam Dose Required for Maintenance of General Anesthesia
This prospective randomized controlled trial evaluates whether intraoperative binaural beats reduce the remimazolam dose required for general anesthesia in 88 adults undergoing breast surgery.
- Trial name
- NCT07311642
- Testing
- biaural beat, control
- Volunteers
- 88 people
- Sponsor
- Seoul National University Hospital
Hip Surgery, Femoral Neck Fractures
Comparison of Lumbar Erector Spinae Plane Block and Spinal Anesthesia in Hip and Proximal Femur Surgery
Hip and proximal femur surgeries are commonly performed in elderly patients and require anesthetic techniques that provide adequate surgical anesthesia while minimizing the need for additional opioid administration.
- Trial name
- L-ESP-HIP Stud (NCT07427082)
- Testing
- Ultrasound-Guided Lumbar Erector Spinae Plane Block (L4), Spinal Anesthesia (L4-L5)
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Gaziantep City Hospital
Hypothermia
Effects of Heat and Moisture Exchanger in Combination With Air Forced Warming Blankets or Warming Intravenous Solutions on Intraoperative Hypothermia Prevention in Obese and Non Obese Patients During Intravenous Anesthesia
The aim of the present study was to evaluate if the combination of heat and moisture exchanger with air forced warming blankets or warming intravenous fluids prevents intraoperative hypothermia in obese and non obese women under…
- Trial name
- NCT01026766
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Inflammation, Postoperative Delirium
Propofol and Dexmedetomidine on Inflammation
Dexmedetomidine, was reported to prevent postoperative delirium in elderly patients following its use in intensive care units. Possible mechanisms included improved quality of sleep and an inhibitory effect on inflammation.
- Conditions
- Inflammation, Postoperative Delirium, Anesthesia
- Trial name
- NCT03600727
- Testing
- Propofol, Dexmedetomidine
- Volunteers
- 200 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
General Anesthesia, Aged
Remimazolam Versus Midazolam for General Anesthesia Induction in Elderly Patients Undergoing Non-Cardiac Surgery
This prospective observational cohort study evaluates the effectiveness and safety of two benzodiazepine sedatives-remimazolam and midazolam-used for general anesthesia induction in elderly patients (≥65 years) undergoing…
- Conditions
- General Anesthesia, Aged, Intraoperative Hypotension, Anxiety
- Trial name
- NCT07746505
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Major Depressive Disorder, Surgery
Intraoperative Ketamine Versus Saline in Depressed Patients Undergoing Anesthesia for Non-cardiac Surgery
This study evaluates whether ketamine, given as part of an anesthetic, improves depression symptoms in depressed patients undergoing non-cardiac surgery.
- Conditions
- Major Depressive Disorder, Surgery, Orthopedic Disorder
- Trial name
- NCT03861988
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Stanford University