Clinical trials: Intra-osseous
Radius Fracture
Magnesium Sulfate and Bupivacaine for Rehabilitation After Distal Radius Fractures
This study evaluates the effect of 10% magnesium sulfate in the rehabilitation of the wrist mobility in patients with distal radius fracture treated with percutaneous pinning and plaster
- Trial name
- NCT02514343
- Testing
- Magnesium Sulfate, Bupivacaine
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Fractures, Comminuted, Fracture Fixation, Internal
Comparative Study of Fixation or Fusion of Calcaneal Fractures
A multicentre randomized controlled trial that will be conducted at Level 1 trauma centres across Canada. It will compare patients who receive open reduction, internal fixation for Sanders IV calcaneal fractures to patients who…
- Trial name
- Sanders IV (NCT00679393)
- Testing
- Open reduction internal fixation, Fusion
- Where
- 4 sites in Canada
- Volunteers
- 26 people
- Sponsor
- University of Calgary
Implant Site Reaction
Peri Implant Marginal Bone Height and Bone Density
This study aims to evaluate the effect of mandibular implant supported removable overdenture on bone height and density and compare it with implant supported fixed overdenture in single mandibular overdenture.
- Trial name
- NCT05974215
- Testing
- assessment of change in bone height by cone beam computed tomography
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Menatallah Mohamed Elhotieby
Distal Radius Fractures, Survey
Predicting Outcomes of Distal Radius Fractures: a Surgeon Survey
The goal of this surgeon survey is to find out if orthopedic and trauma surgeons can predict outcomes in older adults with distal radius fractures.
- Conditions
- Distal Radius Fractures, Survey, Distal Radius Fracture
- Trial name
- SSDART (NCT05942950)
- Where
- Netherlands
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- JointResearch
Myeloid Neoplasms With Myelofibrosis
An Exploratory Study on the Use of Gecacitinib in Patients With Myeloid Malignancies and Myelofibrosis During the Peri-transplant Period Following Allogeneic Hematopoietic Stem Cell Transplantation
This is a single-arm, single-center exploratory study evaluating the safety and efficacy of gecacitinib administered in the peri-transplant period in patients with myeloid neoplasms and myelofibrosis (MF) who are scheduled to…
- Trial name
- JAK-PeriMF (NCT07883382)
- Testing
- gecacitinib Hydrochloride Tablets
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Ruijin Hospital
Peri-Implantitis, Bone Resorption
Surgical Treatment of Peri-implantitis With Adjunctive Application of Platelet Rich Fibrin (PRF)
Platelet-rich fibrin (PRF) is a second-generation platelet concentrate used for tissue and bone regeneration. PRF releases growth factors such as TGF-β, PDGF, VEGF, IGF, and FGF, which are known to promote wound healing and bone…
- Conditions
- Peri-Implantitis, Bone Resorption, Platelet-Rich Fibrin
- Trial name
- PRF (NCT06679283)
- Testing
- Open flap debridement with a chemo-electric device + PRF, Open flap debridement with a chemo-electric device alone (control)
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Bern
Alveolar Bone Loss, Peri-Implantitis
Radiological Bone Loss on Different Levels of Dental Implants
One of the criteria used for long-term implant success is the evaluation of radiographic bone loss. It is known that the keratinized mucosa over the alveolar crest forms a protective barrier against inflammatory infiltration.
- Conditions
- Alveolar Bone Loss, Peri-Implantitis, Bone Loss in Jaw
- Trial name
- NCT05595746
- Testing
- dental implant placement
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Medication Related Osteonecrosis of the Jaw
Comparing Implant Retention Versus Removal for MRONJ at Implant Sites
Medication-related osteonecrosis of the jaw (MRONJ) is a condition that can occur in patients who take medications such as antiresorptive drugs for osteoporosis and other bone-related systemic diseases.
- Trial name
- NCT07435259
- Testing
- Implant Retention Surgery, Implant Removal Sugery
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Kyunghee University Dental Hospital
Osteosarcoma, Bone Cancer
Intra-arterial Cisplatin Plus Rh-endostatin Combined With Systematic Chemotherapy in Osteosarcoma
The goal of this clinical trial is to learn the efficacy and safety of intra-arterial cisplatin plus anti-angiogenesis inhibitor rh-endostatin (Endostar) combined with systematic chemotherapy in osteosarcoma.
- Trial name
- IACE-OS (NCT06562673)
- Testing
- intra-arterial cisplatin plus anti-angiogenesis inhibitor rh-endostatin (Endostar)
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Shanghai 6th People's Hospital