Clinical trials: Intracranial Aneurysm Rupture
Ruptured and Unruptured Intracranial Aneurysms
Mid-term Data Collection of the Treatment of Intracranial Aneurysms With the WEB™ Aneurysm Embolization System
Flow disruption is a new endovascular approach for treatment of both ruptured and unruptured intracranial aneurysms, which involves placement of an endosaccular device (WEB) which modifies the blood flow at the level of the neck…
- Trial name
- NCT03379714
- Testing
- WEB aneurysm embolization system
- Where
- Belgium
- Sponsor
- Medical Therapy Solutions
Subarachnoid Hemorrhage, Aneurysmal
Safety/Pharmacokinetic Study Comparing Intracisternal EG-1962 to Standard of Care Enteral Nimodipine in Adults With aSAH
Safety and Pharmacokinetic study comparing intracisternal EG-1962 to enternal nimopidine in the treatment of aneurysmal subarachnoid hemorrhage.
- Trial name
- NCT02893826
- Testing
- EG-1962 (nimodipine microparticles), Enteral Nimodipine
- Where
- 4 sites in United States, Canada
- Volunteers
- 6 people
- Sponsor
- Edge Therapeutics Inc
Aneurysmal Subarachnoid Hemorrhage, Cerebral Vasospasm
Safety Study of Carotid Body Neurostimulation to Treat Cerebral Vasospasm
The purpose of this study is to evaluate the safety and performance of the Delta system in the treatment of cerebral vasospasm post aneurysmal subarachnoid hemorrhage (aSAH) patients.
- Trial name
- NCT02129413
- Testing
- Delta system
- Where
- 7 sites in Czechia, Germany and 1 more
- Volunteers
- 23 people
- Sponsor
- Samson NeuroSciences
Ruptured Cerebral Aneurysm
Aneurysm Embolization System for Intracranial Aneurysms
The purpose of this clinical study was to evaluate the safety and efficacy of the aneurysm embolization system produced by Jiangsu Changyida Medical Technology Co., Ltd.
- Trial name
- NCT06485492
- Testing
- Implant an aneurysm embolization system
- Volunteers
- 150 people
- Sponsor
- Jiangsu CED Medtech Co., Ltd
Subarachnoid Hemorrhage, Ruptured Intracranial Aneurysm
Safety and Efficacy Study of a Single Dose of NA-1 in Patients Undergoing Endovascular Repair of Ruptured Aneurysms
This is a randomized, double-blind, placebo-controlled, single-dose study investigating the safety and efficacy of NA-1 in patients with subarachnoid hemorrhage (SAH) undergoing endovascular repair of ruptured intracranial…
- Trial name
- ENACT-2 (NCT02056574)
- Testing
- NA-1
- Where
- 12 sites in United States, Canada
- Sponsor
- NoNO Inc.
Aneurysms
TRUfill®'s Line in Intracranial aNeurysm Embolisation
The objective of this study is to evaluate the long term efficacy and safety of the CODMAN TRUFILL®'s line of coils in the treatment of patients with intracranial ruptured or non-ruptured aneurysms in real-life routine clinical…
- Trial name
- TRULINE (NCT01503775)
- Where
- 7 sites in France
- Volunteers
- 171 people
- Sponsor
- Codman & Shurtleff
Ruptured Aneurysm
European, Multi-center, Exploratory Trial to Assess WEB Versus Other Endovascular Treatment in Ruptured Aneurysms.
Comparison of efficacy and safety between WEB and other endovascular techniques
- Trial name
- WAVE (NCT06511245)
- Testing
- Randomisation
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Microvention-Terumo, Inc.
Intracranial Aneurysm, Ruptured Aneurysm
EvaLuate EndoVascular Treatment of Acutely Ruptured Shallow Intradural Aneurysms With the Pipeline™ Flex Embolization Device With Shield TEchnology™ (ELEVATE)
The purpose of the study is to assess the safety and effectiveness of the Pipeline™ Flex Embolization Device with Shield Technology™ in the treatment with acutely ruptured intracranial aneurysms.
- Trial name
- ELEVATE (NCT04391803)
- Testing
- Pipeline™ Flex Embolization Device with Shield Technology™
- Where
- 7 sites in United States
- Volunteers
- 25 people
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Aneurysm, Intracranial Aneurysm
Appraising the Embolization of Aneurysms Using Balt Optima™ Coil System (APPLY Study)
In recent years, many developments have been made to the tools and techniques used to treat IAs via endovascular intervention. Specifically, to the detachable coils themselves.
- Conditions
- Aneurysm, Intracranial Aneurysm, Ruptured Aneurysm, Subarachnoid Hemorrhage, Aneurysmal
- Trial name
- APPLY (NCT04499508)
- Testing
- Optima Coil System
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Vascular Neurology of Southern California Inc.
Intracranial Aneurysm
Medina Embolization Device In Neurovascular Aneurysm Study
A global prospective, multi-center, single-arm, post-market clinical follow-up (PMCF) study conducted to assess the performance of the Medina Embolization Device when used in unruptured and ruptured intracranial aneurysms.
- Trial name
- MEDINA (NCT02982200)
- Where
- 3 sites in Austria, Italy and 1 more
- Volunteers
- 15 people
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Ruptured and Unruptured Intracranial Aneurysms
Mid-term Data Collection of the Treatment of Intracranial Aneurysms With the WEB™ Aneurysm Embolization System
Flow disruption is a new endovascular approach for treatment of both ruptured and unruptured intracranial aneurysms, which involves placement of an endosaccular device (WEB) which modifies the blood flow at the level of the neck…
- Trial name
- NCT03312725
- Testing
- WEB aneurysm embolization system
- Where
- Belgium
- Volunteers
- 1 people
- Sponsor
- Medical Therapy Solutions
Subarachnoid Hemorrhage, Aneurysmal
Study of EG-1962 Compared to Standard of Care Oral Nimodipine in Adults With Aneurysmal Subarachnoid Hemorrhage
This study compares EG-1962 to enteral nimodipine in the treatment of aneurysmal subarachnoid hemorrhage.
- Trial name
- NEWTON2 (NCT02790632)
- Testing
- EG-1962 (nimodipine microparticles), Enteral Nimodipine
- Where
- 79 sites in United States, Australia and 9 more
- Volunteers
- 374 people
- Sponsor
- Edge Therapeutics Inc
Brain Aneurysm
CLARYS: CLinical Assessment of WEB® Device in Ruptured aneurYSms
An observational non-randomized, multi-center, prospective assessment of the clinical utility of the WEB Aneurysm Embolization System in subjects with ruptured intracranial aneurysms deemed appropriate for endovascular treatment.
- Trial name
- CLARYS (NCT02687607)
- Testing
- WEB Aneurysm Embolization System
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Microvention-Terumo, Inc.
Intracranial Saccular Aneurysm, Either Rupture or Unruptured, Wide Neck Aneurysm
Solitaire Aneurysm Remodeling Registry
The objective of the registry is to evaluate the effectiveness and performance of the Solitaire Neurovascular Remodeling Device when used with embolic coils in the treatment of intracranial aneurysms.
- Trial name
- NCT04905303
- Where
- France
- Sponsor
- Medtronic Neurovascular Clinical Affairs